ATE405671T1 - Zusammensetzungen zur verbesserung der card(catalyzed reporter deposition)-technik - Google Patents
Zusammensetzungen zur verbesserung der card(catalyzed reporter deposition)-technikInfo
- Publication number
- ATE405671T1 ATE405671T1 AT02747995T AT02747995T ATE405671T1 AT E405671 T1 ATE405671 T1 AT E405671T1 AT 02747995 T AT02747995 T AT 02747995T AT 02747995 T AT02747995 T AT 02747995T AT E405671 T1 ATE405671 T1 AT E405671T1
- Authority
- AT
- Austria
- Prior art keywords
- substituent
- enhancing
- group
- alkyl
- heteroatom
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000008021 deposition Effects 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 6
- 230000002708 enhancing effect Effects 0.000 abstract 5
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 102000003992 Peroxidases Human genes 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 150000002894 organic compounds Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
- 125000005015 aryl alkynyl group Chemical group 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/895,937 US6617125B2 (en) | 2001-06-29 | 2001-06-29 | Compositions for enhanced catalyzed reporter deposition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405671T1 true ATE405671T1 (de) | 2008-09-15 |
Family
ID=25405324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02747995T ATE405671T1 (de) | 2001-06-29 | 2002-06-28 | Zusammensetzungen zur verbesserung der card(catalyzed reporter deposition)-technik |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6617125B2 (de) |
| EP (1) | EP1414955B1 (de) |
| JP (2) | JP4251984B2 (de) |
| AT (1) | ATE405671T1 (de) |
| AU (1) | AU2002318436B2 (de) |
| CA (1) | CA2451582C (de) |
| DE (1) | DE60228454D1 (de) |
| WO (1) | WO2003002733A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0487435A (ja) * | 1990-07-31 | 1992-03-19 | Fujitsu Ltd | 回線分岐方式 |
| US6617125B2 (en) * | 2001-06-29 | 2003-09-09 | Perkinelmer Life Sciences, Inc. | Compositions for enhanced catalyzed reporter deposition |
| WO2003006676A2 (en) | 2001-07-13 | 2003-01-23 | Nanosphere, Inc. | Method for immobilizing molecules onto surfaces |
| US7297553B2 (en) | 2002-05-28 | 2007-11-20 | Nanosphere, Inc. | Method for attachment of silylated molecules to glass surfaces |
| JP2007089548A (ja) * | 2005-09-30 | 2007-04-12 | Univ Of Tokushima | シグナル増幅方法 |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| JP5639889B2 (ja) | 2007-09-18 | 2014-12-10 | ダコ デンマーク アクティーゼルスカブ | 生物学的標的の高速で高感度な検出方法 |
| EP2282742A1 (de) * | 2008-04-09 | 2011-02-16 | Infinity Pharmaceuticals, Inc. | Inhibitoren von fettsäureamidhydrolase |
| US8541581B2 (en) | 2009-04-07 | 2013-09-24 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| US8546564B2 (en) | 2009-04-07 | 2013-10-01 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| MX361692B (es) | 2010-02-03 | 2018-12-13 | Infinity Pharmaceuticals Inc | Inhibidores de amida hidrolasa de ácido graso. |
| SG10201804238TA (en) | 2010-12-30 | 2018-06-28 | Ventana Med Syst Inc | Enhanced deposition of chromogens utilizing pyrimidine analogs |
| CA2867144C (en) | 2012-03-27 | 2019-07-02 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| CN108368543B (zh) | 2015-10-12 | 2023-06-13 | 领先细胞医疗诊断有限公司 | 高噪声样品中原位检测核苷酸变体及相关的组合物和方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4521511A (en) | 1982-09-22 | 1985-06-04 | Enzyme Technology Company | Catalyzed colorimetric and fluorometric substrates for peroxidase enzyme determinations |
| EP0116454B1 (de) | 1983-02-11 | 1987-04-29 | National Research Development Corporation | Erhöhte lumineszierende oder luminometrische Prüfung |
| GB8420053D0 (en) | 1984-08-07 | 1984-09-12 | Secr Social Service Brit | Enhanced luminescent/luminometric assay |
| US5196306A (en) | 1989-03-29 | 1993-03-23 | E. I. Du Pont De Nemours And Company | Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system |
| GB9119920D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| US5629168A (en) * | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
| US5467287A (en) | 1994-02-09 | 1995-11-14 | Johnson Service Company | Enthalpy calculator |
| JP3727711B2 (ja) | 1996-04-10 | 2005-12-14 | 富士通株式会社 | 画像情報処理装置 |
| US5688966A (en) | 1996-07-26 | 1997-11-18 | E. I. Du Pont De Nemours And Company | Compounds and method for synthesizing sulfoindocyanine dyes |
| US5863748A (en) | 1997-03-14 | 1999-01-26 | New Life Science Products, Inc. | p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system |
| US6372937B1 (en) * | 1998-11-09 | 2002-04-16 | Mark Norman Bobrow | Enhanced catalyzed reporter deposition |
| US6617125B2 (en) * | 2001-06-29 | 2003-09-09 | Perkinelmer Life Sciences, Inc. | Compositions for enhanced catalyzed reporter deposition |
-
2001
- 2001-06-29 US US09/895,937 patent/US6617125B2/en not_active Expired - Lifetime
-
2002
- 2002-06-28 AU AU2002318436A patent/AU2002318436B2/en not_active Expired
- 2002-06-28 WO PCT/US2002/020460 patent/WO2003002733A2/en not_active Ceased
- 2002-06-28 CA CA2451582A patent/CA2451582C/en not_active Expired - Lifetime
- 2002-06-28 EP EP02747995A patent/EP1414955B1/de not_active Expired - Lifetime
- 2002-06-28 AT AT02747995T patent/ATE405671T1/de not_active IP Right Cessation
- 2002-06-28 JP JP2003509095A patent/JP4251984B2/ja not_active Expired - Fee Related
- 2002-06-28 DE DE60228454T patent/DE60228454D1/de not_active Expired - Lifetime
-
2008
- 2008-07-23 JP JP2008189947A patent/JP2009268459A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2451582A1 (en) | 2003-01-09 |
| AU2002318436B2 (en) | 2007-11-01 |
| JP2005500040A (ja) | 2005-01-06 |
| WO2003002733A2 (en) | 2003-01-09 |
| EP1414955A2 (de) | 2004-05-06 |
| EP1414955B1 (de) | 2008-08-20 |
| EP1414955A4 (de) | 2004-10-06 |
| US6617125B2 (en) | 2003-09-09 |
| DE60228454D1 (de) | 2008-10-02 |
| JP4251984B2 (ja) | 2009-04-08 |
| CA2451582C (en) | 2011-05-31 |
| US20030017460A1 (en) | 2003-01-23 |
| WO2003002733A3 (en) | 2003-02-20 |
| JP2009268459A (ja) | 2009-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |