ATE406363T1 - Methylindole und methylpyrrolopyridine als alpha- 1-adrenerge agonisten - Google Patents
Methylindole und methylpyrrolopyridine als alpha- 1-adrenerge agonistenInfo
- Publication number
- ATE406363T1 ATE406363T1 AT04739120T AT04739120T ATE406363T1 AT E406363 T1 ATE406363 T1 AT E406363T1 AT 04739120 T AT04739120 T AT 04739120T AT 04739120 T AT04739120 T AT 04739120T AT E406363 T1 ATE406363 T1 AT E406363T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- alpha
- methylpyrrolopyridines
- methylindoles
- adrenergic agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46925503P | 2003-05-09 | 2003-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406363T1 true ATE406363T1 (de) | 2008-09-15 |
Family
ID=33435226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04739120T ATE406363T1 (de) | 2003-05-09 | 2004-04-30 | Methylindole und methylpyrrolopyridine als alpha- 1-adrenerge agonisten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6979696B2 (de) |
| EP (1) | EP1660484B1 (de) |
| JP (1) | JP4454622B2 (de) |
| KR (1) | KR100751163B1 (de) |
| CN (1) | CN100378097C (de) |
| AT (1) | ATE406363T1 (de) |
| AU (1) | AU2004235923B2 (de) |
| BR (1) | BRPI0410237A (de) |
| CA (1) | CA2523253C (de) |
| DE (1) | DE602004016177D1 (de) |
| ES (1) | ES2313019T3 (de) |
| MX (1) | MXPA05011841A (de) |
| PL (1) | PL1660484T3 (de) |
| RU (1) | RU2313524C2 (de) |
| WO (1) | WO2004099189A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05004929A (es) * | 2002-11-07 | 2005-08-18 | Akzo Nobel Nv | Indoles utiles en el tratamiento de enfermedades relacionadas a receptor de androgeno. |
| TW200602317A (en) * | 2004-04-23 | 2006-01-16 | Akzo Nobel Nv | Novel androgens |
| JP2009510066A (ja) * | 2005-09-29 | 2009-03-12 | ワイス | 血管運動症状（ｖｍｓ）の治療のためのモノアミン再取り込みのモジュレータである１−（１ｈ−インドール−１−イル）−３−（メチルアミノ）−１−フェニルプロパン−２−オール誘導体および関連の化合物 |
| CA2632284A1 (en) | 2005-11-30 | 2007-06-07 | F. Hoffmann-La Roche Ag | 3-amino-2-arylpropyl azaindoles and uses thereof |
| SI2658844T1 (sl) | 2010-12-28 | 2017-02-28 | Sanofi | Novi derivati pirimidina, njihova priprava in njihova farmacevtska uporaba kot inhibitorje AKT(PKB) fosforilacije |
| CN102702196B (zh) * | 2012-06-13 | 2015-01-14 | 南京药石药物研发有限公司 | 3-甲基-7-氮杂吲哚的合成方法 |
| KR102129842B1 (ko) | 2013-10-02 | 2020-07-06 | 주식회사 대웅제약 | 술포닐인돌 유도체 및 이의 제조방법 |
| US10358438B2 (en) * | 2014-07-21 | 2019-07-23 | Arizona Board Of Regents On Behalf Of The University Of Arizona | [3+2] annulation to produce 5-membered heterocyclic compounds |
| KR20250085735A (ko) * | 2022-10-14 | 2025-06-12 | 가부시키가이샤산와카가쿠켄큐쇼 | 이미다졸 유도체 |
| WO2024254218A2 (en) * | 2023-06-05 | 2024-12-12 | The Board Of Regents Of The University Of Texas System | Non-peptide small molecule fgf14:nav1.6 channel complex protein-protein interaction modulators |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3370063A (en) * | 1964-10-05 | 1968-02-20 | Mcneilab Inc | Substituted dimethoxy indoles and method of making the same |
| US3586695A (en) * | 1968-01-26 | 1971-06-22 | Dow Chemical Co | Substituted imidazolinyl indoles |
| GB9011335D0 (en) | 1990-05-21 | 1990-07-11 | Fujisawa Pharmaceutical Co | Indolebutyric acid derivatives and process for preparation thereof |
| WO1994029290A1 (en) | 1993-06-14 | 1994-12-22 | Pfizer Inc. | Secondary amines as antidiabetic and antiobesity agents |
| JPH0887346A (ja) * | 1994-09-14 | 1996-04-02 | Chino Kogyo:Kk | パソコン等デスク上を活用する為の卓上台座器具 |
| US6291489B1 (en) | 1996-11-14 | 2001-09-18 | Pfizer Inc. | Process for substituted pyridines |
| SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
| GB9910110D0 (en) * | 1999-04-30 | 1999-06-30 | Glaxo Group Ltd | Chemical compounds |
| AU2001262113A1 (en) | 2000-03-23 | 2001-10-03 | Bayer Aktiengesellschaft | Indoles for treating diseases that can be treated using thyroid hormones |
| DE10106214A1 (de) * | 2001-02-10 | 2002-08-14 | Boehringer Ingelheim Pharma | Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz |
| BR0307406A (pt) * | 2002-02-01 | 2004-12-28 | Hoffmann La Roche | Indóis substituìdos como agonistas alfa-1 |
-
2004
- 2004-04-30 RU RU2005138143/04A patent/RU2313524C2/ru not_active IP Right Cessation
- 2004-04-30 CA CA2523253A patent/CA2523253C/en not_active Expired - Fee Related
- 2004-04-30 KR KR1020057021188A patent/KR100751163B1/ko not_active Expired - Fee Related
- 2004-04-30 MX MXPA05011841A patent/MXPA05011841A/es active IP Right Grant
- 2004-04-30 BR BRPI0410237-1A patent/BRPI0410237A/pt not_active IP Right Cessation
- 2004-04-30 JP JP2006505343A patent/JP4454622B2/ja not_active Expired - Fee Related
- 2004-04-30 EP EP04739120A patent/EP1660484B1/de not_active Expired - Lifetime
- 2004-04-30 CN CNB2004800122944A patent/CN100378097C/zh not_active Expired - Fee Related
- 2004-04-30 PL PL04739120T patent/PL1660484T3/pl unknown
- 2004-04-30 AT AT04739120T patent/ATE406363T1/de active
- 2004-04-30 WO PCT/EP2004/004609 patent/WO2004099189A1/en not_active Ceased
- 2004-04-30 ES ES04739120T patent/ES2313019T3/es not_active Expired - Lifetime
- 2004-04-30 AU AU2004235923A patent/AU2004235923B2/en not_active Ceased
- 2004-04-30 DE DE602004016177T patent/DE602004016177D1/de not_active Expired - Lifetime
- 2004-05-07 US US10/841,288 patent/US6979696B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006525970A (ja) | 2006-11-16 |
| AU2004235923A1 (en) | 2004-11-18 |
| EP1660484B1 (de) | 2008-08-27 |
| US6979696B2 (en) | 2005-12-27 |
| EP1660484A1 (de) | 2006-05-31 |
| CA2523253C (en) | 2010-06-22 |
| US20040224973A1 (en) | 2004-11-11 |
| WO2004099189A1 (en) | 2004-11-18 |
| BRPI0410237A (pt) | 2006-05-09 |
| PL1660484T3 (pl) | 2009-02-27 |
| JP4454622B2 (ja) | 2010-04-21 |
| KR20060015590A (ko) | 2006-02-17 |
| CN1784397A (zh) | 2006-06-07 |
| ES2313019T3 (es) | 2009-03-01 |
| RU2005138143A (ru) | 2006-08-10 |
| CN100378097C (zh) | 2008-04-02 |
| RU2313524C2 (ru) | 2007-12-27 |
| MXPA05011841A (es) | 2006-01-26 |
| KR100751163B1 (ko) | 2007-08-22 |
| DE602004016177D1 (de) | 2008-10-09 |
| AU2004235923B2 (en) | 2008-01-24 |
| CA2523253A1 (en) | 2004-11-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20025641D0 (no) | Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptor-antagonister | |
| NO20025640D0 (no) | Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptor-antagonister | |
| MXPA04007414A (es) | Indoles sustituidos como agonistas alfa-1. | |
| ATE496620T1 (de) | 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren | |
| DE60208568D1 (de) | Prostaglandinanaloga als ep4-rezeptoragonisten | |
| ATE360630T1 (de) | Azabicyclische heterocyclen als modulatoren des cannabinoidrezeptors | |
| SE0302760D0 (sv) | New compounds | |
| DE60305484D1 (de) | Verbindungen und deren verwendung als 5-ht inhibitore | |
| DE602004009200D1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| ATE519486T1 (de) | Pharmazeutische zusammensetzung mit einem monoamin-neurotransmitter-wiederaufnahmehemmer und einem acetylcholinesterase-hemmer | |
| TW200508207A (en) | New benzimidazole derivatives | |
| SE0403171D0 (sv) | New compounds | |
| ATE386725T1 (de) | Heterocyclylverbindungen | |
| ATE417838T1 (de) | Arylsulfonyl-derivate mit 5-ht 6-rezeptor- affinität | |
| DE60313350D1 (de) | Pyrimidin-2,4-dion-derivate als matrix-metalloproteinase-hemmer | |
| PL374019A1 (en) | Benzoxazine derivatives as 5-ht6 modulators and uses thereof | |
| DE60208178D1 (de) | Chinolin-4-carboxamidderivate als nk-3 und nk-2 rezeptor antagonisten | |
| MXPA04005076A (es) | Derivados de 4-piperidinil alquilamina como antagonistas del receptor muscarinico. | |
| ATE406363T1 (de) | Methylindole und methylpyrrolopyridine als alpha- 1-adrenerge agonisten | |
| MXPA04005313A (es) | Derivados de aminotetralin como antagonistas del receptor muscarinico. | |
| ATE447575T1 (de) | Selektive spirocyclische glucocorticoid-rezeptor- modulatoren | |
| MXPA05011476A (es) | Imidazolin-2-il-aminofenil-amidas como antagonistas de prostaglandina i2. | |
| SE0403118D0 (sv) | New compounds 2 | |
| SE0301371D0 (sv) | New Compounds | |
| BR0112957A (pt) | Composto, método de tratamento, uso de um composto, e, composição farmacêutica |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1660484 Country of ref document: EP |