ATE406379T1 - Einschlusskomplexe von perindopril - Google Patents

Einschlusskomplexe von perindopril

Info

Publication number: ATE406379T1
Authority: AT; Austria
Prior art keywords: perindopril; inclusion complexes; complexes; inclusion; perindopril erbumine
Prior art date: 2004-01-14

Application number

AT05700892T

Other languages

English (en)

Inventor

Rudolf Rucman

Original Assignee

Lek Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-14

Filing date

2005-01-13

Publication date

2008-09-15

2005-01-13 Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals

2008-09-15 Application granted granted Critical

2008-09-15 Publication of ATE406379T1 publication Critical patent/ATE406379T1/de

Links

IPVQLZZIHOAWMC-QXKUPLGCSA-N perindopril Chemical compound C1CCC[C@H]2C[C@@H](C(O)=O)N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H]21 IPVQLZZIHOAWMC-QXKUPLGCSA-N 0.000 title 1
229960002582 perindopril Drugs 0.000 title 1
229960003929 perindopril erbumine Drugs 0.000 abstract 1
IYNMDWMQHSMDDE-MHXJNQAMSA-N perindopril erbumine Chemical compound CC(C)(C)N.C1CCC[C@@H]2N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H](C(O)=O)C[C@@H]21 IYNMDWMQHSMDDE-MHXJNQAMSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Glass Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Battery Electrode And Active Subsutance (AREA)

AT05700892T 2004-01-14 2005-01-13 Einschlusskomplexe von perindopril ATE406379T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SI200400011A SI21703A (en)	2004-01-14	2004-01-14	Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia

Publications (1)

Publication Number	Publication Date
ATE406379T1 true ATE406379T1 (de)	2008-09-15

Family

ID=34793532

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05700892T ATE406379T1 (de)	2004-01-14	2005-01-13	Einschlusskomplexe von perindopril

Country Status (7)

Country	Link
EP (2)	EP2003142A1 (de)
AT (1)	ATE406379T1 (de)
DE (1)	DE602005009319D1 (de)
PL (1)	PL1709066T3 (de)
RU (1)	RU2372353C2 (de)
SI (2)	SI21703A (de)
WO (1)	WO2005068490A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20140476T1 (hr) *	2005-11-17	2014-07-18	Silverstone Pharma Est.	Stabilni oblik amorfnih soli perindoprila, postupak njihove pripreme, posebno industrijske pripreme i njihova uporaba u lijeäśenju hipertenzije
EP1815857A1 (de) *	2006-02-02	2007-08-08	LEK Pharmaceuticals D.D.	Pharmazeutische Zusammensetzung enthaltend Perindopril
EP1998749A1 (de) *	2007-04-13	2008-12-10	Helm AG	Verfahren zur herstellung von perindopril-ter-butylamin-adsorbaten
SI22542A (sl) *	2007-06-04	2008-12-31	Diagen D.O.O.	Stabilna formulacija amorfnih soli perindoprila, postopek za njeno pripravo v industrijskem merilu in njena uporaba za zdravljenje hipertenzije
SI22543A (sl)	2007-06-27	2008-12-31	Krka, Tovarna Zdravil, D.D., Novo Mesto	Nove soli perindoprila

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2503155A2 (fr)	1980-10-02	1982-10-08	Science Union & Cie	Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
US4508729A (en)	1979-12-07	1985-04-02	Adir	Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
FR2620709B1 (fr) *	1987-09-17	1990-09-07	Adir	Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
SI9500140A (en)	1995-04-24	1996-10-31	Genesis Para La Investigacion	Novel n-sulfoxy anhydrides, process for the preparation thereof and its use for the preparation of bioactive substances having ace inhibitory action
UA57734C2 (uk) *	1996-05-07	2003-07-15	Пфайзер Інк.	Комплекси включення арилгетероциклічних солей
FR2772615B1 (fr) *	1997-12-23	2002-06-14	Lipha	Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
FR2811320B1 (fr)	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811318B1 (fr)	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811319B1 (fr)	2000-07-06	2002-08-23	Adir	Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
HRP20000765A2 (en) *	2000-11-10	2002-06-30	Pliva D D	Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
AR036187A1 (es)	2001-07-24	2004-08-18	Adir	Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario
SI21506A (sl) *	2003-05-08	2004-12-31	LEK farmacevtska dru�ba d.d.	Postopek za pripravo perindoprila

2004
- 2004-01-14 SI SI200400011A patent/SI21703A/sl not_active IP Right Cessation
2005
- 2005-01-13 EP EP08162970A patent/EP2003142A1/de not_active Withdrawn
- 2005-01-13 DE DE602005009319T patent/DE602005009319D1/de not_active Expired - Lifetime
- 2005-01-13 RU RU2006129349/04A patent/RU2372353C2/ru not_active IP Right Cessation
- 2005-01-13 AT AT05700892T patent/ATE406379T1/de not_active IP Right Cessation
- 2005-01-13 EP EP05700892A patent/EP1709066B1/de not_active Expired - Lifetime
- 2005-01-13 PL PL05700892T patent/PL1709066T3/pl unknown
- 2005-01-13 SI SI200530479T patent/SI1709066T1/sl unknown
- 2005-01-13 WO PCT/EP2005/000282 patent/WO2005068490A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP1709066A1 (de)	2006-10-11
EP1709066B1 (de)	2008-08-27
RU2006129349A (ru)	2008-02-20
SI1709066T1 (sl)	2009-02-28
WO2005068490A1 (en)	2005-07-28
EP2003142A1 (de)	2008-12-17
SI21703A (en)	2005-08-31
DE602005009319D1 (de)	2008-10-09
PL1709066T3 (pl)	2009-02-27
RU2372353C2 (ru)	2009-11-10

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Legal Events

Date	Code	Title	Description
2009-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties