BRPI0513149A - uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituìdas no tratamento de náuseas e vÈmito - Google Patents

uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituìdas no tratamento de náuseas e vÈmito

Info

Publication number
BRPI0513149A
BRPI0513149A BRPI0513149-9A BRPI0513149A BRPI0513149A BR PI0513149 A BRPI0513149 A BR PI0513149A BR PI0513149 A BRPI0513149 A BR PI0513149A BR PI0513149 A BRPI0513149 A BR PI0513149A
Authority
BR
Brazil
Prior art keywords
dicyano
nausea
vomiting
thio
phenyl
Prior art date
Application number
BRPI0513149-9A
Other languages
English (en)
Inventor
Thomas Krahn
Wolfgang Thielemann
Ulrich Rosentreter
Nicole Diedrichs
Thomas Kromer
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of BRPI0513149A publication Critical patent/BRPI0513149A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

USO DE 2-TIO-3,5-DICIANO-4-FENIL-6-AMINOPIRIDINAS SUBSTITUìDAS NO TRATAMENTO DE NáUSEA E VÈMITO. A presente invenção refere-se ao uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituídas de fórmula (I) para preparação de um medicamento para profilaxia e/ou tratamento de náusea e vómito.
BRPI0513149-9A 2004-07-06 2005-06-23 uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituìdas no tratamento de náuseas e vÈmito BRPI0513149A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004032651A DE102004032651A1 (de) 2004-07-06 2004-07-06 Verwendung von substituierten 2-Thio-3,5-dicyano-4-phenyl-6-aminopyriden bei der Behandlung von Übelkeit und Erbrechen
PCT/EP2005/006779 WO2006002823A1 (de) 2004-07-06 2005-06-23 Verwendung von substituierten 2-thio-3,5-dicyano-4-phenyl-6-aminopyridinen bei der behandlung von übelkeit und erbrechen

Publications (1)

Publication Number Publication Date
BRPI0513149A true BRPI0513149A (pt) 2008-04-29

Family

ID=34970906

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513149-9A BRPI0513149A (pt) 2004-07-06 2005-06-23 uso de 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituìdas no tratamento de náuseas e vÈmito

Country Status (18)

Country Link
US (1) US7709504B2 (pt)
EP (1) EP1765343B1 (pt)
JP (1) JP2008505139A (pt)
KR (1) KR20070041561A (pt)
CN (1) CN101014342A (pt)
AT (1) ATE446753T1 (pt)
AU (1) AU2005259506A1 (pt)
BR (1) BRPI0513149A (pt)
CA (1) CA2572990A1 (pt)
DE (2) DE102004032651A1 (pt)
EC (1) ECSP077130A (pt)
ES (1) ES2333805T3 (pt)
IL (1) IL180551A0 (pt)
MA (1) MA28707B1 (pt)
MX (1) MX2007000224A (pt)
NO (1) NO20070608L (pt)
RU (1) RU2007104234A (pt)
WO (1) WO2006002823A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10110747A1 (de) * 2001-03-07 2002-09-12 Bayer Ag Substituierte 2,6-Diamino-3,5-dicyano-4-aryl-pyridine und ihre Verwendung
DE102004042607A1 (de) * 2004-09-03 2006-03-09 Bayer Healthcare Ag Substituierte Phenylaminothiazole und ihre Verwendung
DE102006042143A1 (de) * 2006-09-08 2008-03-27 Bayer Healthcare Aktiengesellschaft Neue substituierte Bipyridin-Derivate und ihre Verwendung
DE102006056739A1 (de) * 2006-12-01 2008-06-05 Bayer Healthcare Ag Substituierte 4-Amino-3,5-dicyano-2-thiopyridine und ihre Verwendung
DE102006056740A1 (de) * 2006-12-01 2008-06-05 Bayer Healthcare Ag Cyclisch substituierte 3,5-Dicyano-2-thiopyridine und ihre Verwendung
DE102007035367A1 (de) 2007-07-27 2009-01-29 Bayer Healthcare Ag Substituierte Aryloxazole und ihre Verwendung
DE102007036076A1 (de) 2007-08-01 2009-02-05 Bayer Healthcare Aktiengesellschaft Dipeptoid-Produgs und ihre Verwendung
DE102007061764A1 (de) * 2007-12-20 2009-06-25 Bayer Healthcare Ag Anellierte Cyanopyridine und ihre Verwendung
DE102007061763A1 (de) * 2007-12-20 2009-06-25 Bayer Healthcare Ag Substituierte azabicyclische Verbindungen und ihre Verwendung
DE102008013587A1 (de) * 2008-03-11 2009-09-17 Bayer Schering Pharma Aktiengesellschaft Heteroaryl-substituierte Dicyanopyridine und ihre Verwendung
JP2011520997A (ja) * 2008-05-29 2011-07-21 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト ２−アルコキシ置換ジシアノピリジン類およびそれらの使用
DE102008062567A1 (de) 2008-12-16 2010-06-17 Bayer Schering Pharma Aktiengesellschaft Dipeptoid-Prodrugs und ihre Verwendung
DE102009006602A1 (de) * 2009-01-29 2010-08-05 Bayer Schering Pharma Aktiengesellschaft Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs
DE102010030688A1 (de) 2010-06-30 2012-01-05 Bayer Schering Pharma Aktiengesellschaft Substituierte Dicyanopyridine und ihre Verwendung
US20120058983A1 (en) * 2010-09-02 2012-03-08 Bayer Pharma Aktiengesellschaft Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension
TWI903299B (zh) 2018-03-08 2025-11-01 美商英塞特公司 作為PI3K-γ抑制劑之胺基吡嗪二醇化合物
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
WO2025038781A1 (en) * 2023-08-15 2025-02-20 Lucy Therapeutics, Inc. Adenosine ligands for the treatment of neurological disorders or chronic heart failure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0105469D0 (en) * 2001-03-06 2001-04-25 Glaxo Group Ltd Medicaments
DE10115922A1 (de) * 2001-03-30 2002-10-10 Bayer Ag Cyclisch substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
DE10134481A1 (de) * 2001-07-16 2003-01-30 Bayer Ag Substituierte 2-Thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre Verwendung
DE10238113A1 (de) * 2001-12-11 2003-06-18 Bayer Ag Substituierte 2-Thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre Verwendung
PL372145A1 (en) * 2002-02-19 2005-07-11 Cv Therapeutics, Inc. Partial and full agonists of a sb 1 /sb adenosine receptors

Also Published As

Publication number Publication date
NO20070608L (no) 2007-02-01
KR20070041561A (ko) 2007-04-18
CN101014342A (zh) 2007-08-08
US20080249133A1 (en) 2008-10-09
CA2572990A1 (en) 2006-01-12
EP1765343B1 (de) 2009-10-28
DE102004032651A1 (de) 2006-02-16
AU2005259506A1 (en) 2006-01-12
MA28707B1 (fr) 2007-06-01
ES2333805T3 (es) 2010-03-01
ATE446753T1 (de) 2009-11-15
ECSP077130A (es) 2007-02-28
EP1765343A1 (de) 2007-03-28
WO2006002823A1 (de) 2006-01-12
MX2007000224A (es) 2007-06-15
JP2008505139A (ja) 2008-02-21
DE502005008416D1 (de) 2009-12-10
IL180551A0 (en) 2008-03-20
US7709504B2 (en) 2010-05-04
RU2007104234A (ru) 2008-08-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]