ATE406936T1 - Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten - Google Patents
Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamentenInfo
- Publication number
- ATE406936T1 ATE406936T1 AT00926064T AT00926064T ATE406936T1 AT E406936 T1 ATE406936 T1 AT E406936T1 AT 00926064 T AT00926064 T AT 00926064T AT 00926064 T AT00926064 T AT 00926064T AT E406936 T1 ATE406936 T1 AT E406936T1
- Authority
- AT
- Austria
- Prior art keywords
- electroporation
- gene
- protein
- array
- drug delivery
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 238000004520 electroporation Methods 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000012377 drug delivery Methods 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12981799P | 1999-04-16 | 1999-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406936T1 true ATE406936T1 (de) | 2008-09-15 |
Family
ID=22441736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00926064T ATE406936T1 (de) | 1999-04-16 | 2000-04-17 | Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6593130B1 (de) |
| EP (1) | EP1210144B1 (de) |
| AT (1) | ATE406936T1 (de) |
| AU (1) | AU4465600A (de) |
| DE (1) | DE60040156D1 (de) |
| WO (1) | WO2000062855A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8177743B2 (en) | 1998-05-18 | 2012-05-15 | Boston Scientific Scimed, Inc. | Localized delivery of drug agents |
| US7729756B2 (en) * | 2000-01-18 | 2010-06-01 | Siemens Aktiengesellschaft | Measurement system for examining a section of tissue on a patient and the use of a measurement system of this type |
| JP4310108B2 (ja) * | 2001-04-06 | 2009-08-05 | 中外製薬株式会社 | 脈管系又は尿管を介して遺伝子を導入する方法 |
| WO2003047689A1 (en) * | 2001-11-29 | 2003-06-12 | Microlin Llc | Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices |
| US7104985B2 (en) * | 2003-03-06 | 2006-09-12 | Martinelli Michael A | Apparatus and method for causing selective necrosis of abnormal cells |
| US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
| US8802643B1 (en) | 2003-05-30 | 2014-08-12 | University Of South Florida | Method for the treatment of malignancies |
| CN1798502A (zh) | 2003-05-30 | 2006-07-05 | 南佛罗里达大学 | 治疗恶性肿瘤的方法 |
| US7297786B2 (en) * | 2004-07-09 | 2007-11-20 | University Of Iowa Research Foundation | RNA interference in respiratory epitheial cells |
| US7729761B2 (en) * | 2004-07-14 | 2010-06-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlled gene or protein delivery |
| US7776373B2 (en) * | 2004-11-19 | 2010-08-17 | Eteka Llc | Apparatus and method for the enhancement of food properties and food prepared therefrom |
| US7923251B2 (en) * | 2005-02-23 | 2011-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for avalanche-mediated transfer of agents into cells |
| US8101169B2 (en) * | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
| US20080182251A1 (en) * | 2005-03-19 | 2008-07-31 | Luyi Sen | Ultra Low Strength Electric Field Network-Mediated Ex Vivo Gene, Protein and Drug Delivery in Cells |
| EP1759714A1 (de) * | 2005-09-02 | 2007-03-07 | Bioalliance Pharma | Elektrotransfer von Nukleinsäuren in Gewebezellen |
| WO2007117651A2 (en) * | 2006-04-07 | 2007-10-18 | University Of South Florida | Passive electric field focus system for in vivo and in vitro applications |
| US20100121253A1 (en) * | 2007-03-14 | 2010-05-13 | The Regents Of The University Of California | Method and Apparatus of Low Strength Electric Field Network-Mediated Delivery of Drug, Gene, SI-RNA, SH-RNA Protein, Peptide, Antibody or Other Biomedical and Therapeutic Molecules and Reagents in Solid Organs |
| US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
| JP2011513004A (ja) * | 2008-03-06 | 2011-04-28 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 折り目を有するバルーンを備えたバルーンカテーテル器具 |
| CN101274120B (zh) | 2008-04-29 | 2013-03-13 | 圣太科医疗科技(上海)有限公司 | 生物与医用多路低电压微电场发生仪 |
| KR101719824B1 (ko) | 2008-05-09 | 2017-04-04 | 호라이라 인코포레이티드 | 기관지나무 치료용 시스템, 어셈블리 및 방법 |
| JP2011520448A (ja) * | 2008-05-13 | 2011-07-21 | バイオ−ラッド ラボラトリーズ,インコーポレイティド | 密集した電極のアレイでの付着細胞の電気穿孔法 |
| EP2319579A4 (de) * | 2008-07-18 | 2012-12-26 | Suntek Medical Scient And Technologies Shanghai | Gerät zur abgabe eines arzneimittels an ein zellziel in der leber unter verwendung eines elektrischen feldnetzes geringer stärke |
| US20110117635A1 (en) * | 2008-07-18 | 2011-05-19 | Luyi Sen | Multipurpose Micro Electric Field Network Cell Processing Device |
| US8207138B2 (en) | 2009-05-19 | 2012-06-26 | Medtronic, Inc. | Methods and devices for improved efficiency of RNA delivery to cells |
| US20100298697A1 (en) * | 2009-05-19 | 2010-11-25 | Medtronic, Inc. | Method and devices for improved efficiency of rna delivery to cells |
| US8932055B2 (en) * | 2009-06-11 | 2015-01-13 | Roberto Armanino | Method employing electric fields to selectively kill microbes in a root canal preparation |
| EP2445584A4 (de) | 2009-06-24 | 2014-06-11 | Internat Scient Pty Ltd | Vorrichtung und behandlungsverfahren mit einem variierenden elektromagnetischen energisierungsprofil |
| WO2011028419A1 (en) * | 2009-08-27 | 2011-03-10 | Boston Scientific Scimed, Inc. | Balloon catheter devices with drug-coated sheath |
| EP2926757B1 (de) | 2009-10-27 | 2023-01-25 | Nuvaira, Inc. | Freisetzungsvorrichtungen mit kühlbaren energieemissionsanordnungen |
| WO2011057137A1 (en) | 2009-11-05 | 2011-05-12 | Neuronexus Technologies | Waveguide neural interface device |
| US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
| AU2010319477A1 (en) | 2009-11-11 | 2012-05-24 | Holaira, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
| US20120070829A1 (en) | 2010-09-10 | 2012-03-22 | Bio-Rad Laboratories, Inc. | Size selection of dna for chromatin analysis |
| WO2012112606A1 (en) | 2011-02-15 | 2012-08-23 | Bio-Rad Laboratories, Inc. | Detecting methylati0n in a subpopulation of genomic dna |
| US8728987B2 (en) | 2011-08-03 | 2014-05-20 | Bio-Rad Laboratories, Inc. | Filtering small nucleic acids using permeabilized cells |
| US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
| WO2019147613A1 (en) * | 2018-01-23 | 2019-08-01 | The Regents Of The University Of California | Downstream delivery of agents in solid organ transplantation |
| US10918861B2 (en) * | 2018-07-24 | 2021-02-16 | Wisconsin Alumni Research Foundation | In vivo gene therapy delivery procedure and device |
| CN113677392B (zh) * | 2018-10-26 | 2024-09-17 | 凯拓盘公司 | 用于电穿孔的装置、系统和套件及其使用方法 |
| WO2025186424A1 (en) | 2024-03-07 | 2025-09-12 | Diagenode S.A. | Methods for cut&tag |
| EP4613870A1 (de) | 2024-03-07 | 2025-09-10 | Diagenode S.A. | Verfahren für cut&tag |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5236413B1 (en) | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
| US5507724A (en) | 1992-07-01 | 1996-04-16 | Genetronics, Inc. | Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells |
| US5304120A (en) | 1992-07-01 | 1994-04-19 | Btx Inc. | Electroporation method and apparatus for insertion of drugs and genes into endothelial cells |
| US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
| US5634899A (en) * | 1993-08-20 | 1997-06-03 | Cortrak Medical, Inc. | Simultaneous cardiac pacing and local drug delivery method |
| US5807306A (en) | 1992-11-09 | 1998-09-15 | Cortrak Medical, Inc. | Polymer matrix drug delivery apparatus |
| US5795755A (en) * | 1994-07-05 | 1998-08-18 | Lemelson; Jerome H. | Method of implanting living cells by laser poration at selected sites |
| US6041252A (en) * | 1995-06-07 | 2000-03-21 | Ichor Medical Systems Inc. | Drug delivery system and method |
| US6090617A (en) * | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
| CA2285056C (en) | 1997-04-03 | 2004-12-14 | Iacob Mathiesen | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
| US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
-
2000
- 2000-04-14 US US09/549,904 patent/US6593130B1/en not_active Expired - Lifetime
- 2000-04-17 EP EP00926064A patent/EP1210144B1/de not_active Expired - Lifetime
- 2000-04-17 WO PCT/US2000/010337 patent/WO2000062855A1/en not_active Ceased
- 2000-04-17 AT AT00926064T patent/ATE406936T1/de not_active IP Right Cessation
- 2000-04-17 AU AU44656/00A patent/AU4465600A/en not_active Abandoned
- 2000-04-17 DE DE60040156T patent/DE60040156D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000062855A1 (en) | 2000-10-26 |
| AU4465600A (en) | 2000-11-02 |
| DE60040156D1 (de) | 2008-10-16 |
| US6593130B1 (en) | 2003-07-15 |
| EP1210144B1 (de) | 2008-09-03 |
| EP1210144A1 (de) | 2002-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |