ATE406936T1 - Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten - Google Patents

Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten

Info

Publication number
ATE406936T1
ATE406936T1 AT00926064T AT00926064T ATE406936T1 AT E406936 T1 ATE406936 T1 AT E406936T1 AT 00926064 T AT00926064 T AT 00926064T AT 00926064 T AT00926064 T AT 00926064T AT E406936 T1 ATE406936 T1 AT E406936T1
Authority
AT
Austria
Prior art keywords
electroporation
gene
protein
array
drug delivery
Prior art date
Application number
AT00926064T
Other languages
English (en)
Inventor
Luyi Sen
Guanggen Cui
Jack Judy
Hillel Laks
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE406936T1 publication Critical patent/ATE406936T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT00926064T 1999-04-16 2000-04-17 Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten ATE406936T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12981799P 1999-04-16 1999-04-16

Publications (1)

Publication Number Publication Date
ATE406936T1 true ATE406936T1 (de) 2008-09-15

Family

ID=22441736

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00926064T ATE406936T1 (de) 1999-04-16 2000-04-17 Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten

Country Status (6)

Country Link
US (1) US6593130B1 (de)
EP (1) EP1210144B1 (de)
AT (1) ATE406936T1 (de)
AU (1) AU4465600A (de)
DE (1) DE60040156D1 (de)
WO (1) WO2000062855A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
US7729756B2 (en) * 2000-01-18 2010-06-01 Siemens Aktiengesellschaft Measurement system for examining a section of tissue on a patient and the use of a measurement system of this type
JP4310108B2 (ja) * 2001-04-06 2009-08-05 中外製薬株式会社 脈管系又は尿管を介して遺伝子を導入する方法
WO2003047689A1 (en) * 2001-11-29 2003-06-12 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US7104985B2 (en) * 2003-03-06 2006-09-12 Martinelli Michael A Apparatus and method for causing selective necrosis of abnormal cells
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US8802643B1 (en) 2003-05-30 2014-08-12 University Of South Florida Method for the treatment of malignancies
CN1798502A (zh) 2003-05-30 2006-07-05 南佛罗里达大学 治疗恶性肿瘤的方法
US7297786B2 (en) * 2004-07-09 2007-11-20 University Of Iowa Research Foundation RNA interference in respiratory epitheial cells
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US7776373B2 (en) * 2004-11-19 2010-08-17 Eteka Llc Apparatus and method for the enhancement of food properties and food prepared therefrom
US7923251B2 (en) * 2005-02-23 2011-04-12 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for avalanche-mediated transfer of agents into cells
US8101169B2 (en) * 2005-02-23 2012-01-24 The Board Of Trustees Of The Leland Stanford Junior University Ocular gene therapy using avalanche-mediated transfection
US20080182251A1 (en) * 2005-03-19 2008-07-31 Luyi Sen Ultra Low Strength Electric Field Network-Mediated Ex Vivo Gene, Protein and Drug Delivery in Cells
EP1759714A1 (de) * 2005-09-02 2007-03-07 Bioalliance Pharma Elektrotransfer von Nukleinsäuren in Gewebezellen
WO2007117651A2 (en) * 2006-04-07 2007-10-18 University Of South Florida Passive electric field focus system for in vivo and in vitro applications
US20100121253A1 (en) * 2007-03-14 2010-05-13 The Regents Of The University Of California Method and Apparatus of Low Strength Electric Field Network-Mediated Delivery of Drug, Gene, SI-RNA, SH-RNA Protein, Peptide, Antibody or Other Biomedical and Therapeutic Molecules and Reagents in Solid Organs
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
JP2011513004A (ja) * 2008-03-06 2011-04-28 ボストン サイエンティフィック サイムド,インコーポレイテッド 折り目を有するバルーンを備えたバルーンカテーテル器具
CN101274120B (zh) 2008-04-29 2013-03-13 圣太科医疗科技(上海)有限公司 生物与医用多路低电压微电场发生仪
KR101719824B1 (ko) 2008-05-09 2017-04-04 호라이라 인코포레이티드 기관지나무 치료용 시스템, 어셈블리 및 방법
JP2011520448A (ja) * 2008-05-13 2011-07-21 バイオ−ラッド ラボラトリーズ,インコーポレイティド 密集した電極のアレイでの付着細胞の電気穿孔法
EP2319579A4 (de) * 2008-07-18 2012-12-26 Suntek Medical Scient And Technologies Shanghai Gerät zur abgabe eines arzneimittels an ein zellziel in der leber unter verwendung eines elektrischen feldnetzes geringer stärke
US20110117635A1 (en) * 2008-07-18 2011-05-19 Luyi Sen Multipurpose Micro Electric Field Network Cell Processing Device
US8207138B2 (en) 2009-05-19 2012-06-26 Medtronic, Inc. Methods and devices for improved efficiency of RNA delivery to cells
US20100298697A1 (en) * 2009-05-19 2010-11-25 Medtronic, Inc. Method and devices for improved efficiency of rna delivery to cells
US8932055B2 (en) * 2009-06-11 2015-01-13 Roberto Armanino Method employing electric fields to selectively kill microbes in a root canal preparation
EP2445584A4 (de) 2009-06-24 2014-06-11 Internat Scient Pty Ltd Vorrichtung und behandlungsverfahren mit einem variierenden elektromagnetischen energisierungsprofil
WO2011028419A1 (en) * 2009-08-27 2011-03-10 Boston Scientific Scimed, Inc. Balloon catheter devices with drug-coated sheath
EP2926757B1 (de) 2009-10-27 2023-01-25 Nuvaira, Inc. Freisetzungsvorrichtungen mit kühlbaren energieemissionsanordnungen
WO2011057137A1 (en) 2009-11-05 2011-05-12 Neuronexus Technologies Waveguide neural interface device
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
AU2010319477A1 (en) 2009-11-11 2012-05-24 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US20120070829A1 (en) 2010-09-10 2012-03-22 Bio-Rad Laboratories, Inc. Size selection of dna for chromatin analysis
WO2012112606A1 (en) 2011-02-15 2012-08-23 Bio-Rad Laboratories, Inc. Detecting methylati0n in a subpopulation of genomic dna
US8728987B2 (en) 2011-08-03 2014-05-20 Bio-Rad Laboratories, Inc. Filtering small nucleic acids using permeabilized cells
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
WO2019147613A1 (en) * 2018-01-23 2019-08-01 The Regents Of The University Of California Downstream delivery of agents in solid organ transplantation
US10918861B2 (en) * 2018-07-24 2021-02-16 Wisconsin Alumni Research Foundation In vivo gene therapy delivery procedure and device
CN113677392B (zh) * 2018-10-26 2024-09-17 凯拓盘公司 用于电穿孔的装置、系统和套件及其使用方法
WO2025186424A1 (en) 2024-03-07 2025-09-12 Diagenode S.A. Methods for cut&tag
EP4613870A1 (de) 2024-03-07 2025-09-10 Diagenode S.A. Verfahren für cut&tag

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236413B1 (en) 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
US5507724A (en) 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US5304120A (en) 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
US5807306A (en) 1992-11-09 1998-09-15 Cortrak Medical, Inc. Polymer matrix drug delivery apparatus
US5795755A (en) * 1994-07-05 1998-08-18 Lemelson; Jerome H. Method of implanting living cells by laser poration at selected sites
US6041252A (en) * 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
US6090617A (en) * 1996-12-05 2000-07-18 Entremed, Inc. Flow electroporation chamber with electrodes having a crystalline metal nitride coating
CA2285056C (en) 1997-04-03 2004-12-14 Iacob Mathiesen Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle
US6010573A (en) * 1998-07-01 2000-01-04 Virginia Commonwealth University Apparatus and method for endothelial cell seeding/transfection of intravascular stents

Also Published As

Publication number Publication date
WO2000062855A1 (en) 2000-10-26
AU4465600A (en) 2000-11-02
DE60040156D1 (de) 2008-10-16
US6593130B1 (en) 2003-07-15
EP1210144B1 (de) 2008-09-03
EP1210144A1 (de) 2002-06-05

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