ATE410681T1 - Funktionelles screenungsverfahren mittels protein translokation/redistribution - Google Patents
Funktionelles screenungsverfahren mittels protein translokation/redistributionInfo
- Publication number
- ATE410681T1 ATE410681T1 AT03765149T AT03765149T ATE410681T1 AT E410681 T1 ATE410681 T1 AT E410681T1 AT 03765149 T AT03765149 T AT 03765149T AT 03765149 T AT03765149 T AT 03765149T AT E410681 T1 ATE410681 T1 AT E410681T1
- Authority
- AT
- Austria
- Prior art keywords
- redistribution
- screening method
- functional screening
- protein translocation
- protein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 230000007398 protein translocation Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000011331 genomic analysis Methods 0.000 abstract 1
- 238000012804 iterative process Methods 0.000 abstract 1
- 230000004853 protein function Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0216674.2A GB0216674D0 (en) | 2002-07-18 | 2002-07-18 | Functional screening method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE410681T1 true ATE410681T1 (de) | 2008-10-15 |
Family
ID=9940685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03765149T ATE410681T1 (de) | 2002-07-18 | 2003-07-10 | Funktionelles screenungsverfahren mittels protein translokation/redistribution |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050272035A1 (de) |
| EP (1) | EP1523678B1 (de) |
| JP (1) | JP4532270B2 (de) |
| AT (1) | ATE410681T1 (de) |
| AU (1) | AU2003254442B2 (de) |
| CA (1) | CA2493409C (de) |
| DE (1) | DE60323983D1 (de) |
| DK (1) | DK1523678T3 (de) |
| ES (1) | ES2314249T3 (de) |
| GB (1) | GB0216674D0 (de) |
| IL (1) | IL166238A0 (de) |
| WO (1) | WO2004009847A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101147147B1 (ko) | 2004-04-01 | 2012-05-25 | 머크 샤프 앤드 돔 코포레이션 | Ｒｎａ 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드 |
| GB0410105D0 (en) * | 2004-05-06 | 2004-06-09 | Amersham Biosciences Uk Ltd | Method for characterising compounds |
| US7923207B2 (en) * | 2004-11-22 | 2011-04-12 | Dharmacon, Inc. | Apparatus and system having dry gene silencing pools |
| AU2007299705B2 (en) | 2006-09-22 | 2012-09-06 | Dharmacon, Inc. | Duplex oligonucleotide complexes and methods for gene silencing by RNA interference |
| GB0624462D0 (en) * | 2006-12-07 | 2007-01-17 | Ge Healthcare Ltd | Method for determining gentoxicity |
| US8188060B2 (en) | 2008-02-11 | 2012-05-29 | Dharmacon, Inc. | Duplex oligonucleotides with enhanced functionality in gene regulation |
| US8741591B2 (en) | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
| WO2016013008A1 (en) * | 2014-07-21 | 2016-01-28 | Novellusdx Ltd. | Methods and systems for determining oncogenic index of patient specific mutations |
| CN111500545A (zh) * | 2020-04-30 | 2020-08-07 | 中国农业科学院农业质量标准与检测技术研究所 | 基于转基因工程细胞株测定糖皮质激素类混合物的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69804446T3 (de) * | 1997-04-07 | 2006-08-24 | Bioimage A/S | Verfahren um quantitativen informationen über einflüsse auf zelluläre reaktionen zu entnehmen |
| AU1957299A (en) * | 1998-01-09 | 1999-07-26 | Governing Council Of The University Of Toronto, The | Presenilin protein interactions |
| AU5790199A (en) * | 1998-10-05 | 2000-04-26 | Duke University | Method and apparatus for detecting binding interactions (in vivo) |
| WO2000068661A2 (en) * | 1999-05-12 | 2000-11-16 | Gordon Adrienne S | Detection of cellular exposure to addictive drugs |
-
2002
- 2002-07-18 GB GBGB0216674.2A patent/GB0216674D0/en not_active Ceased
-
2003
- 2003-07-10 JP JP2004522291A patent/JP4532270B2/ja not_active Expired - Fee Related
- 2003-07-10 DE DE60323983T patent/DE60323983D1/de not_active Expired - Lifetime
- 2003-07-10 AT AT03765149T patent/ATE410681T1/de not_active IP Right Cessation
- 2003-07-10 CA CA002493409A patent/CA2493409C/en not_active Expired - Fee Related
- 2003-07-10 WO PCT/GB2003/002983 patent/WO2004009847A2/en not_active Ceased
- 2003-07-10 EP EP03765149A patent/EP1523678B1/de not_active Expired - Lifetime
- 2003-07-10 ES ES03765149T patent/ES2314249T3/es not_active Expired - Lifetime
- 2003-07-10 US US10/521,495 patent/US20050272035A1/en not_active Abandoned
- 2003-07-10 AU AU2003254442A patent/AU2003254442B2/en not_active Ceased
- 2003-07-10 DK DK03765149T patent/DK1523678T3/da active
-
2005
- 2005-01-11 IL IL16623805A patent/IL166238A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60323983D1 (de) | 2008-11-20 |
| EP1523678A2 (de) | 2005-04-20 |
| CA2493409A1 (en) | 2004-01-29 |
| ES2314249T3 (es) | 2009-03-16 |
| EP1523678B1 (de) | 2008-10-08 |
| IL166238A0 (en) | 2006-01-15 |
| WO2004009847A3 (en) | 2004-04-15 |
| JP4532270B2 (ja) | 2010-08-25 |
| CA2493409C (en) | 2009-06-09 |
| WO2004009847A2 (en) | 2004-01-29 |
| DK1523678T3 (da) | 2009-02-02 |
| AU2003254442B2 (en) | 2006-11-02 |
| US20050272035A1 (en) | 2005-12-08 |
| GB0216674D0 (en) | 2002-08-28 |
| AU2003254442A1 (en) | 2004-02-09 |
| JP2005532817A (ja) | 2005-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |