ATE411300T1 - Neue cysteine protease hemmers und ihre therapeutische anwendungen - Google Patents

Neue cysteine protease hemmers und ihre therapeutische anwendungen

Info

Publication number
ATE411300T1
ATE411300T1 AT05291683T AT05291683T ATE411300T1 AT E411300 T1 ATE411300 T1 AT E411300T1 AT 05291683 T AT05291683 T AT 05291683T AT 05291683 T AT05291683 T AT 05291683T AT E411300 T1 ATE411300 T1 AT E411300T1
Authority
AT
Austria
Prior art keywords
hemmers
therapeutic applications
cysteine protease
new cysteine
new
Prior art date
Application number
AT05291683T
Other languages
English (en)
Inventor
Philippe Guedat
Guillaume Boissy
Catherine Borg-Capra
Frederic Colland
Laurent Daviet
Etienne Formstecher
Xavier Jacq
Jean-Christophe Rain
Remi Delansorne
Stefania Vallese
Matteo Colombo
Original Assignee
Hybrigenics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybrigenics Sa filed Critical Hybrigenics Sa
Application granted granted Critical
Publication of ATE411300T1 publication Critical patent/ATE411300T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT05291683T 2005-08-05 2005-08-05 Neue cysteine protease hemmers und ihre therapeutische anwendungen ATE411300T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05291683A EP1749822B1 (de) 2005-08-05 2005-08-05 Neue Cysteine Protease Hemmers und ihre therapeutische Anwendungen

Publications (1)

Publication Number Publication Date
ATE411300T1 true ATE411300T1 (de) 2008-10-15

Family

ID=35583351

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05291683T ATE411300T1 (de) 2005-08-05 2005-08-05 Neue cysteine protease hemmers und ihre therapeutische anwendungen

Country Status (4)

Country Link
EP (1) EP1749822B1 (de)
CN (1) CN101282946B (de)
AT (1) ATE411300T1 (de)
DE (1) DE602005010421D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011033502A2 (en) * 2009-09-16 2011-03-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pesticidal compositions comprising 4,5-dihydroxyindan-1-one
US20110177105A1 (en) 2010-01-15 2011-07-21 Roman Lopez Novel Selective Inhibitors of Ubiquitin Specific Protease 7, the Pharmaceutical Compositions Thereof and Their Therapeutic Applications
EP2686320B1 (de) * 2011-03-15 2016-05-18 Merck Sharp & Dohme Corp. Tricyclische gyrase-inhibitoren
EP2565186A1 (de) 2011-09-02 2013-03-06 Hybrigenics S.A. Spezifische und reversible Inhibitoren von ubiquitinspezifischer Protease 7
SG11201401608PA (en) * 2011-10-19 2014-07-30 Vivolux Ab Method for inhibition of deubiquitinating activity
EP2807165B1 (de) * 2012-01-27 2019-05-15 Université de Montréal Pyrimido-[4,5-b-]indolderivate und verwendung davon in der expansion von hämatopoetischen stammzellen
WO2016165007A1 (en) * 2015-04-17 2016-10-20 The University Of British Columbia Inhibitors of estrogen receptor alpha and their use as therapeutics for cancer
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Ｐｉｍ激酶抑制劑之鹽
CN111995589B (zh) 2015-11-10 2023-12-05 国立大学法人九州大学 2,5－二氰基－3,6－二卤代吡嗪的制造方法
MX383505B (es) * 2016-07-06 2025-03-14 Univ Texas Eliminación de la cistina mediada por enzimas humanas.
GB201617758D0 (en) 2016-10-20 2016-12-07 Almac Discovery Limited Pharmaceutical compounds
GB202001980D0 (en) 2020-02-13 2020-04-01 Almac Discovery Ltd Therapeutic mentods
GB202200753D0 (en) 2022-01-21 2022-03-09 Almac Discovery Ltd Pharmaceutical compounds
CN116621778A (zh) * 2022-04-29 2023-08-22 北京华森英诺生物科技有限公司 Usp抑制剂、其制备方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0798508B2 (ja) 1985-05-01 1995-10-25 ヤマハ発動機株式会社 小型船舶の船体構造
JP3219339B2 (ja) 1993-06-15 2001-10-15 株式会社リコー ピラジン化合物及びそれを含有する電子写真感光体
JPH07175235A (ja) 1993-12-20 1995-07-14 Ricoh Co Ltd 単層型電子写真用感光体
JP3255525B2 (ja) 1993-12-23 2002-02-12 株式会社リコー ピラジン化合物及びそれを含有する電子写真感光体
JPH07199486A (ja) 1993-12-30 1995-08-04 Ricoh Co Ltd 電子写真用感光体
JPH07199487A (ja) 1993-12-30 1995-08-04 Ricoh Co Ltd 電子写真用感光体
JPH07281460A (ja) 1994-04-14 1995-10-27 Ricoh Co Ltd 潜像転写用電子写真感光体
CN1245486A (zh) * 1996-12-11 2000-02-23 Basf公司 用作钙蛋白酶抑制剂的酮苯甲酰胺
JP2000122316A (ja) 1998-10-19 2000-04-28 Ricoh Co Ltd 電子写真感光体
JP2000128885A (ja) 1998-10-19 2000-05-09 Ricoh Co Ltd テトラピラジノポルフィラジン化合物及びその製造方法
AU2002305926A1 (en) * 2001-02-05 2002-10-08 Exegenics Inc. Cysteine protease inhibitors
WO2003005585A1 (en) 2001-07-06 2003-01-16 Telefonaktiebolaget L.M. Ericsson A signal generator device, method for generating a signal and devices including such a signal generator device
HUP0402344A2 (hu) * 2001-12-04 2005-02-28 F. Hoffmann-La Roche Ag Helyettesített 2-amino-cikloalkán-karboxamidok, felhasználásuk cisztein-proteáz-inhibitorként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
EP1537074B1 (de) * 2002-09-04 2019-02-27 Merck Canada Inc. Cathepsin-cystein-protease-inhibitoren

Also Published As

Publication number Publication date
CN101282946B (zh) 2013-08-14
EP1749822B1 (de) 2008-10-15
CN101282946A (zh) 2008-10-08
DE602005010421D1 (de) 2008-11-27
EP1749822A1 (de) 2007-02-07

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