ATE411811T1 - Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie - Google Patents

Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie

Info

Publication number: ATE411811T1
Authority: AT; Austria
Prior art keywords: ophthalmology; synthetic peptides; complementary synthetic; peptides; complementary
Prior art date: 1999-03-09

Application number

AT00913818T

Other languages

English (en)

Inventor

Jeffrey Haddox

James Blalock

Robert Pfister

Matteo Villain

Original Assignee

Fornix Biosciences N V

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-09

Filing date

2000-03-08

Publication date

2008-11-15

2000-03-08 Application filed by Fornix Biosciences N V filed Critical Fornix Biosciences N V

2008-11-15 Application granted granted Critical

2008-11-15 Publication of ATE411811T1 publication Critical patent/ATE411811T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
230000000295 complement effect Effects 0.000 title abstract 2
BRPMXFSTKXXNHF-IUCAKERBSA-N (2s)-1-[2-[[(2s)-pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid Chemical group OC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H]1NCCC1 BRPMXFSTKXXNHF-IUCAKERBSA-N 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
239000002975 chemoattractant Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000224 granular leucocyte Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT00913818T 1999-03-09 2000-03-08 Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie ATE411811T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12340999P	1999-03-09	1999-03-09

Publications (1)

Publication Number	Publication Date
ATE411811T1 true ATE411811T1 (de)	2008-11-15

Family

ID=22408525

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00913818T ATE411811T1 (de)	1999-03-09	2000-03-08	Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie

Country Status (8)

Country	Link
US (2)	US6310041B1 (de)
EP (1)	EP1560590B1 (de)
AT (1)	ATE411811T1 (de)
AU (1)	AU3518700A (de)
CA (1)	CA2366678A1 (de)
DE (1)	DE60040623D1 (de)
ES (1)	ES2316356T3 (de)
WO (1)	WO2000053621A2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040202645A1 (en) *	2003-04-08	2004-10-14	Khan Nisar Ahmed	Administration of gene-regulatory peptides
US8680059B2 (en) *	1998-05-20	2014-03-25	Biotempt B.V.	Oligopeptide acetate and formulations thereof
US6921751B1 (en) *	1998-05-20	2005-07-26	Erasmus Universiteit Rotterdam	Immunoregulator
US20030220258A1 (en)	2001-12-21	2003-11-27	Robbert Benner	Treatment of ischemic events
US6844315B2 (en)	1998-05-20	2005-01-18	Erasmus Universiteit Rotterdam	Immunoregulator
US20050227925A1 (en) *	2004-04-08	2005-10-13	Robbert Benner	Compositions capable of reducing elevated blood urea concentration
EP1138692A1 (de)	2000-03-29	2001-10-04	Erasmus Universiteit Rotterdam	Fragmente des menschlichen Choriongonadotropins als Immunoregulatoren
ATE411811T1 (de) *	1999-03-09	2008-11-15	Fornix Biosciences N V	Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie
NL1011737C2 (nl) *	1999-04-06	2000-10-09	Ct For Immunopharmacology	Verbinding voor het remmen van de influx van polymorphonucleaire leukocyten (PMNs) in een weefsel, werkwijze voor het selecteren van een dergelijke verbinding, een farmaceutisch preparaat en een toepassing van de verbinding.
US7358330B2 (en) *	2001-03-29	2008-04-15	Biotempt B.V.	Immunoregulatory compositions
US7501391B2 (en) *	2001-12-21	2009-03-10	Biotempt B.V.	Treatment of transplant survival
US20040013661A1 (en) *	2001-12-21	2004-01-22	Gert Wensvoort	Stratification
US20030220260A1 (en) *	2001-12-21	2003-11-27	Khan Nisar Ahmed	Peptide compositions
US20030220257A1 (en) *	2001-12-21	2003-11-27	Robbert Benner	Treatment of trauma
US7786084B2 (en) *	2001-12-21	2010-08-31	Biotempt B.V.	Treatment of burns
US7560433B2 (en)	2001-12-21	2009-07-14	Biotempt B.V.	Treatment of multiple sclerosis (MS)
US20080242837A1 (en) *	2001-12-21	2008-10-02	Khan Nisar A	Peptide compositions
US20030220261A1 (en) *	2001-12-21	2003-11-27	Khan Nisar Ahmed	Treatment of iatrogenic disease
US20080318871A1 (en) *	2001-12-21	2008-12-25	Khan Nisar A	Treatment of neurological disorders
US20030224995A1 (en) *	2001-12-21	2003-12-04	Khan Nisar Ahmed	Treatment of burns
EP1509609B1 (de) *	2002-06-04	2015-04-22	DSM IP Assets B.V.	An tripeptiden reiches protein hydrolysat
US20090227505A1 (en) *	2004-01-07	2009-09-10	Biotempt B.V.	Methods and uses for protein breakdown products
RU2252778C1 (ru) *	2004-01-20	2005-05-27	Институт Молекулярной Генетики Российской Академии Наук (Имг Ран)	Применение трипептида pro-gly-pro в качестве средства профилактики и лечения диабета, способ профилактики и лечения диабета и фармацевтическая композиция для профилактики и лечения диабета
WO2007004869A2 (en) *	2005-07-05	2007-01-11	Biotempt B.V.	Treatment of tumors
WO2007035406A1 (en)	2005-09-16	2007-03-29	Orthologic Corp.	Antibodies to complementary peptides of thrombin or portions thereof
RU2303602C2 (ru) *	2006-02-17	2007-07-27	Закрытое акционерное общество "Синтез пептидов"	Способ получения трипептидов
EP1864692A1 (de)	2006-06-07	2007-12-12	Biotempt B.V.	Verwendung von peptiden zum Schutz von Strahlenschäden
KR101247641B1 (ko)	2010-10-22	2013-03-29	성균관대학교산학협력단	Ｃｘｃｒ２에 결합하는 펩타이드 리간드를 포함하는 감염성 및 염증성 질환 치료용 조성물
WO2017217728A1 (ko) *	2016-06-13	2017-12-21	부산대학교 산학협력단	Ac-pgp 펩타이드를 유효성분으로 포함하는 혈관 신생 촉진용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5077195A (en) *	1985-03-01	1991-12-31	Board Of Reagents, The University Of Texas System	Polypeptides complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known and methods of design therefor
US5242902A (en) *	1989-09-06	1993-09-07	The Regents Of The University Of California	Defensin peptide compositions and methods for their use
US5916872A (en) *	1996-07-24	1999-06-29	Intrabiotics Pharmaceuticals, Inc.	Cyclic peptides having broad spectrum antimicrobial activity
AU2459400A (en) *	1999-02-12	2000-08-29	Kyowa Hakko Kogyo Co. Ltd.	Peptides inhibiting vascular endothelial cell migration
ATE411811T1 (de) *	1999-03-09	2008-11-15	Fornix Biosciences N V	Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie
NL1011737C2 (nl) *	1999-04-06	2000-10-09	Ct For Immunopharmacology	Verbinding voor het remmen van de influx van polymorphonucleaire leukocyten (PMNs) in een weefsel, werkwijze voor het selecteren van een dergelijke verbinding, een farmaceutisch preparaat en een toepassing van de verbinding.

2000
- 2000-03-08 AT AT00913818T patent/ATE411811T1/de not_active IP Right Cessation
- 2000-03-08 WO PCT/US2000/006062 patent/WO2000053621A2/en not_active Ceased
- 2000-03-08 DE DE60040623T patent/DE60040623D1/de not_active Expired - Fee Related
- 2000-03-08 CA CA002366678A patent/CA2366678A1/en not_active Abandoned
- 2000-03-08 EP EP00913818A patent/EP1560590B1/de not_active Expired - Lifetime
- 2000-03-08 ES ES00913818T patent/ES2316356T3/es not_active Expired - Lifetime
- 2000-03-08 AU AU35187/00A patent/AU3518700A/en not_active Abandoned
- 2000-03-08 US US09/521,365 patent/US6310041B1/en not_active Expired - Fee Related
2001
- 2001-09-28 US US09/967,003 patent/US6762166B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1560590A4 (de)	2005-08-10
US20020107202A1 (en)	2002-08-08
ES2316356T3 (es)	2009-04-16
EP1560590A2 (de)	2005-08-10
WO2000053621A3 (en)	2005-06-16
CA2366678A1 (en)	2000-09-14
EP1560590B1 (de)	2008-10-22
DE60040623D1 (de)	2008-12-04
US6762166B2 (en)	2004-07-13
WO2000053621A2 (en)	2000-09-14
US6310041B1 (en)	2001-10-30
AU3518700A (en)	2000-09-28

Legal Events

Date	Code	Title	Description
2009-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60040623D1 (de)	2008-12-04	Komplementäre, synthetische peptide und ihre nutzung in der ophthalmologie
DE69938786D1 (de)	2008-07-03	Die verwendung von peptiden von il-2 und peptid-derivaten als therapeutische wirkstoffe
EA199901031A1 (ru)	2000-06-26	Производные бензимидазола
DE69434181D1 (de)	2005-01-13	Therapeutische Peptid Derivate
DE69616480D1 (de)	2001-12-06	Piperidinderivate als neurokininantagonisten
ATE218581T1 (de)	2002-06-15	Cyclosporinderivat, dessen herstellung und pharmazeutische zusammensetzung
DE60331546D1 (de)	2010-04-15	Verwendung von aspartic proteasen in den bereichen kosmetik und behandlung
IL112111A0 (en)	1995-03-15	Peptide derivatives and pharmaceutical compositions containing them
ATE313557T1 (de)	2006-01-15	Modifiziertes, als medikamentvorstufe anwendbares cyclosporin und dessen verwendung
ATE407947T1 (de)	2008-09-15	Proteine mit il-6 inhibitorischer wirkung
FI973221A0 (fi)	1997-08-04	1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina
ATE110742T1 (de)	1994-09-15	Peptid-verbindungen.
HUT76926A (hu)	1998-01-28	Új elasztáz inhibitorok
ATE414100T1 (de)	2008-11-15	Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen
DE69524971D1 (de)	2002-02-14	Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen
ATE201693T1 (de)	2001-06-15	Hämoregulierende peptide
BR9814188A (pt)	2000-10-03	"agonistas de 5-ht1f"
ATE165594T1 (de)	1998-05-15	Triarylethylenderivate zur therapeutischen verwendung
FI20012082A0 (fi)	2001-10-26	Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi
BR9611904A (pt)	1999-04-06	Dioxidos de ditiazol
YU70903A (sh)	2006-05-25	Novi peptid ligandi za integrine leukocita
TR199800850T2 (xx)	1998-09-21	Kan� d�zenleyici bile�imler.
LT2002131A (en)	2003-06-25	New use of fir oil for cosmetic
DE69937998D1 (de)	2008-03-06	Antiproliferative und antivirale proteine und peptide
ATE92934T1 (de)	1993-08-15	Synthetische peptide, die zellulaere immunitaet gegen den aids-virus und dessen proteine erzeugen.