ATE411974T1 - Verfahren zur gewinnung von gereinigtem hydroxytyrosol aus von dem olivenbaum erhaltenen produkten und nebenprodukten - Google Patents
Verfahren zur gewinnung von gereinigtem hydroxytyrosol aus von dem olivenbaum erhaltenen produkten und nebenproduktenInfo
- Publication number
- ATE411974T1 ATE411974T1 AT02710893T AT02710893T ATE411974T1 AT E411974 T1 ATE411974 T1 AT E411974T1 AT 02710893 T AT02710893 T AT 02710893T AT 02710893 T AT02710893 T AT 02710893T AT E411974 T1 ATE411974 T1 AT E411974T1
- Authority
- AT
- Austria
- Prior art keywords
- products
- hydroxytyrosol
- obtaining purified
- olive tree
- pomaces
- Prior art date
Links
- JUUBCHWRXWPFFH-UHFFFAOYSA-N Hydroxytyrosol Chemical compound OCCC1=CC=C(O)C(O)=C1 JUUBCHWRXWPFFH-UHFFFAOYSA-N 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 229940095066 hydroxytyrosol Drugs 0.000 title abstract 3
- 235000003248 hydroxytyrosol Nutrition 0.000 title abstract 3
- 239000006227 byproduct Substances 0.000 title abstract 2
- 239000000047 product Substances 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical class C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 240000007817 Olea europaea Species 0.000 abstract 1
- 235000002725 Olea europaea Nutrition 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000004880 explosion Methods 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/265—Adsorption chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200100346A ES2177457B1 (es) | 2000-10-06 | 2001-02-15 | Mejoras introducidas en la patente principal n- 200002422 relativa a un procedimiento de obtencion de hidroxitirosol purificado a partir de productos y subproductos derivados del olivo. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE411974T1 true ATE411974T1 (de) | 2008-11-15 |
Family
ID=8496750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02710893T ATE411974T1 (de) | 2001-02-15 | 2002-02-08 | Verfahren zur gewinnung von gereinigtem hydroxytyrosol aus von dem olivenbaum erhaltenen produkten und nebenprodukten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6849770B2 (de) |
| EP (1) | EP1369407B1 (de) |
| AT (1) | ATE411974T1 (de) |
| AU (1) | AU2002229784B2 (de) |
| DE (1) | DE60229501D1 (de) |
| ES (1) | ES2315351T3 (de) |
| MA (1) | MA26001A1 (de) |
| PT (1) | PT1369407E (de) |
| TN (1) | TNSN03056A1 (de) |
| WO (1) | WO2002064537A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6416808B1 (en) * | 2000-09-01 | 2002-07-09 | Creagri, Inc. | Method of obtaining a hydroxytyrosol-rich composition from vegetation water |
| US7713569B2 (en) * | 2000-09-01 | 2010-05-11 | Creagri, Inc. | Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof |
| CA2474798C (en) * | 2002-02-13 | 2012-12-04 | Creagri, Inc. | Method and composition for treatment of inflammation and aids-associated neurological disorders |
| ES2199069B1 (es) * | 2002-07-17 | 2005-02-01 | Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas, (C.I.E.M.A.T) | Procedimiento para la extraccion de compuestos fenolicos a partir de un material vegetal residual mediante un tratamiento hidrotermico. |
| US20050103711A1 (en) * | 2003-11-18 | 2005-05-19 | Wayne Emmons | Isolation of oleuropein aglycon from olive vegetation water |
| WO2006020588A1 (en) * | 2004-08-09 | 2006-02-23 | Creagri, Inc. | Olive compositions and methods for treating inflammatory conditions |
| WO2007039262A1 (en) * | 2005-09-30 | 2007-04-12 | Dsm Ip Assets B.V. | Novel compositions containing polyphenols |
| ES2291111B1 (es) | 2006-02-17 | 2009-03-16 | Universidad De Granada | Procedimiento de aprovechamiento industrial de tirosol e hidroxitirosol contenidos en los subproductos solidos de la molturacion industrial de la aceituna. |
| US8968811B2 (en) | 2007-01-26 | 2015-03-03 | Probelte Pharma, S.A. | Hydroxytrosol containing extract obtained from olives and solids containing residues of olive oil extraction |
| US8236993B2 (en) * | 2007-01-26 | 2012-08-07 | Probelte Pharma, S.A. | Process and apparatus for the production of hydroxytyrosol containing extract from olives and solids containing residues of olive oil extraction |
| EP1982707A1 (de) * | 2007-04-18 | 2008-10-22 | DSMIP Assets B.V. | Verwendung von Hydroxytyrosol als Mittel gegen des Altern |
| US20100130620A1 (en) * | 2007-04-18 | 2010-05-27 | Jiankang Liu | Novel use of hydroxytyrosol and olive extracts/concentrates containing it |
| CN101298411B (zh) * | 2007-04-30 | 2010-05-19 | 天津市尖峰天然产物研究开发有限公司 | 从橄榄提取液中提取羟基酪醇的方法 |
| ES2311401B1 (es) * | 2007-05-22 | 2009-12-22 | Ges-Biolives, S.L. | Procedimiento para la obtencion de extractos con alto contenido en hidroxitirosol a partir de productos derivados de la oliva. |
| JP2010536352A (ja) * | 2007-08-21 | 2010-12-02 | ディーエスエム アイピー アセッツ ビー.ブイ. | 蒸留されたオリーブ果汁抽出物の製造方法 |
| ES2341526B1 (es) * | 2008-12-19 | 2011-06-08 | Consejo Superior De Investigaciones Cientificas (Csic) | Procedimiento de purificacion de 3,4-dihidroxifenilglicol (dhfg) a partir de productos vegetales. |
| IT1395509B1 (it) * | 2009-09-02 | 2012-09-28 | Bionap Srl | Composizione per il trattamento della patologia emorroidaria e delle patologie correlate |
| US8465939B2 (en) * | 2010-03-02 | 2013-06-18 | Nox Technologies, Inc. | Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof |
| ES2395317B1 (es) * | 2011-07-08 | 2014-04-16 | Consejo Superior De Investigaciones Cientificas (Csic) | Procedimiento para la obtención de extracto de hidroxitirosol, extracto mezcla de hidroxitirosol y 3,4-dihidroxifenilglicol, y extracto de acetato de hidroxitirosilo, a partir de subproductos del olivo y su purificación. |
| ES2367734B2 (es) * | 2011-07-11 | 2012-03-16 | Universidad De Granada | Procedimiento de extracción de �?cidos triterpénicos e hidroxitirosol a partir de soluciones de aderezo de aceitunas. |
| EP2999354B1 (de) * | 2013-04-26 | 2019-06-26 | The Regents of the University of California | Verfahren zur entbitterung von oliven |
| US9420820B2 (en) | 2013-08-09 | 2016-08-23 | University Of Tsukuba | Method for isolating polyphenols from olive mill water |
| CN104402680B (zh) * | 2014-12-12 | 2016-05-11 | 黑龙江八一农垦大学 | 一种通过离子交换树脂转化橄榄苦苷制备羟基酪醇的方法 |
| CN104744220A (zh) * | 2015-02-05 | 2015-07-01 | 黑龙江八一农垦大学 | 一种通过离子交换树脂转化橄榄苦苷制备羟基酪醇的方法 |
| ES2671137B1 (es) | 2016-11-03 | 2019-03-12 | Consejo Superior Investigacion | Uso del 3,4-dihidroxifenilglicol (dhfg) como fitorregulador |
| ES2685169B1 (es) | 2017-03-31 | 2019-08-06 | Procedimiento para obtener aceite de oliva y al menos un extracto concentrado en polifenoles y un ingrediente funcional | |
| ES3010132T3 (en) | 2018-06-20 | 2025-04-01 | Kellanova | Volatile or semi-volatile natural antioxidants sourced from a comestible byproduct |
| EP3818837B1 (de) | 2019-11-07 | 2023-08-30 | Michel Rumiz | Verfahren zur reduzierung der oleuropeinkonzentration und bildung und erhaltung der hydroxythrosol- und tyrosolkonzentration in oliven |
| CN112608404B (zh) * | 2020-12-01 | 2023-01-10 | 石河子大学 | 一种氨基功能化异质结构多孔微球及其制备方法和应用 |
| CN113860999A (zh) * | 2021-10-12 | 2021-12-31 | 东莞职业技术学院 | 一种利用油橄榄叶制备羟基酪醇的方法 |
| CN120183769B (zh) * | 2025-03-18 | 2026-03-24 | 西安迈斯拓扑科技有限公司 | 一种用于光核反应法制备铅-212和锕-225的分离纯化方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2143939B1 (es) * | 1998-02-26 | 2000-12-16 | Consejo Superior Investigacion | Procedimiento de obtencion de manitol a partir de pulpa extractada de aceitunas. |
| ES2145701B1 (es) * | 1998-03-30 | 2001-02-01 | Consejo Superior Investigacion | Procedimiento de obtencion de hidroxitirosol a partir de hueso de aceituna. |
| US6358542B2 (en) | 1999-12-20 | 2002-03-19 | Usana, Inc. | Antioxidant compositions extracted from olives and olive by-products |
| ES2170006B1 (es) * | 2000-08-11 | 2003-11-01 | Consejo Superior Investigacion | Sintesis enzimatica del antioxidante hidroxitirosol. |
| US6416808B1 (en) * | 2000-09-01 | 2002-07-09 | Creagri, Inc. | Method of obtaining a hydroxytyrosol-rich composition from vegetation water |
-
2002
- 2002-02-08 TN TNPCT/ES2002/000058A patent/TNSN03056A1/fr unknown
- 2002-02-08 DE DE60229501T patent/DE60229501D1/de not_active Expired - Fee Related
- 2002-02-08 EP EP02710893A patent/EP1369407B1/de not_active Expired - Lifetime
- 2002-02-08 PT PT02710893T patent/PT1369407E/pt unknown
- 2002-02-08 WO PCT/ES2002/000058 patent/WO2002064537A1/es not_active Ceased
- 2002-02-08 AT AT02710893T patent/ATE411974T1/de not_active IP Right Cessation
- 2002-02-08 ES ES02710893T patent/ES2315351T3/es not_active Expired - Lifetime
- 2002-02-08 AU AU2002229784A patent/AU2002229784B2/en not_active Ceased
-
2003
- 2003-08-13 US US10/640,408 patent/US6849770B2/en not_active Expired - Fee Related
- 2003-08-13 MA MA27278A patent/MA26001A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20040102657A1 (en) | 2004-05-27 |
| EP1369407B1 (de) | 2008-10-22 |
| US6849770B2 (en) | 2005-02-01 |
| WO2002064537A1 (es) | 2002-08-22 |
| ES2315351T3 (es) | 2009-04-01 |
| DE60229501D1 (de) | 2008-12-04 |
| TNSN03056A1 (fr) | 2005-04-08 |
| EP1369407A1 (de) | 2003-12-10 |
| MA26001A1 (fr) | 2003-12-31 |
| PT1369407E (pt) | 2009-01-22 |
| AU2002229784B2 (en) | 2006-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |