BRPI0413326A - métodos para tratar doença cardiovasculares empregando-se uma molécula ctla4 solúvel - Google Patents

métodos para tratar doença cardiovasculares empregando-se uma molécula ctla4 solúvel

Info

Publication number
BRPI0413326A
BRPI0413326A BRPI0413326-9A BRPI0413326A BRPI0413326A BR PI0413326 A BRPI0413326 A BR PI0413326A BR PI0413326 A BRPI0413326 A BR PI0413326A BR PI0413326 A BRPI0413326 A BR PI0413326A
Authority
BR
Brazil
Prior art keywords
methods
soluble ctla4
cardiovascular disease
employing
treating cardiovascular
Prior art date
Application number
BRPI0413326-9A
Other languages
English (en)
Inventor
James Rusnak
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BRPI0413326A publication Critical patent/BRPI0413326A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Mycology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"MéTODOS PARA TRATAR DOENçA CARDIOVASCULAR EMPREGANDO-SE UMA MOLéCULA CTLA4 SOLúVEL". A presente invenção refere-se à composições e métodos para tratar doenças do sistema cardiovascular administrando-se a um indivíduo moléculas CTLA4 solúvel que bloqueiam moléculas B7 endógenas de ligarem-se a seus ligandos.
BRPI0413326-9A 2003-08-04 2004-08-03 métodos para tratar doença cardiovasculares empregando-se uma molécula ctla4 solúvel BRPI0413326A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49243003P 2003-08-04 2003-08-04
PCT/US2004/024840 WO2005016266A2 (en) 2003-08-04 2004-08-03 Methods for treating cardiovascular disease using a soluble ctla4 molecule

Publications (1)

Publication Number Publication Date
BRPI0413326A true BRPI0413326A (pt) 2006-10-10

Family

ID=34193123

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413326-9A BRPI0413326A (pt) 2003-08-04 2004-08-03 métodos para tratar doença cardiovasculares empregando-se uma molécula ctla4 solúvel

Country Status (15)

Country Link
US (3) US7307064B2 (pt)
EP (1) EP1670499A4 (pt)
JP (1) JP2007501243A (pt)
KR (2) KR20090087514A (pt)
CN (1) CN1863546A (pt)
AU (2) AU2004264901B2 (pt)
BR (1) BRPI0413326A (pt)
CA (2) CA2762015A1 (pt)
MX (1) MXPA06001225A (pt)
NO (1) NO20060477L (pt)
NZ (2) NZ573652A (pt)
RU (1) RU2353384C2 (pt)
SG (1) SG144925A1 (pt)
WO (1) WO2005016266A2 (pt)
ZA (1) ZA200601031B (pt)

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Also Published As

Publication number Publication date
NZ573652A (en) 2009-11-27
US20050123539A1 (en) 2005-06-09
WO2005016266A2 (en) 2005-02-24
US20090041790A1 (en) 2009-02-12
US20090068203A1 (en) 2009-03-12
MXPA06001225A (es) 2006-04-11
WO2005016266A3 (en) 2005-07-07
CA2534474A1 (en) 2005-02-24
NZ545314A (en) 2009-03-31
NO20060477L (no) 2006-04-04
AU2009243460B2 (en) 2012-03-01
EP1670499A2 (en) 2006-06-21
CA2762015A1 (en) 2005-02-24
KR20060132541A (ko) 2006-12-21
RU2353384C2 (ru) 2009-04-27
JP2007501243A (ja) 2007-01-25
AU2004264901A1 (en) 2005-02-24
ZA200601031B (en) 2007-05-30
US7671022B2 (en) 2010-03-02
KR20090087514A (ko) 2009-08-17
SG144925A1 (en) 2008-08-28
RU2006106636A (ru) 2006-09-10
CA2534474C (en) 2014-09-23
EP1670499A4 (en) 2009-07-22
AU2009243460B9 (en) 2012-03-15
CN1863546A (zh) 2006-11-15
AU2004264901B2 (en) 2009-12-10
AU2009243460A1 (en) 2009-12-24
US7307064B2 (en) 2007-12-11

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