ATE412734T1 - Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation - Google Patents

Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation

Info

Publication number
ATE412734T1
ATE412734T1 AT96905630T AT96905630T ATE412734T1 AT E412734 T1 ATE412734 T1 AT E412734T1 AT 96905630 T AT96905630 T AT 96905630T AT 96905630 T AT96905630 T AT 96905630T AT E412734 T1 ATE412734 T1 AT E412734T1
Authority
AT
Austria
Prior art keywords
transplantation
myoblasts
preconditioning
vito
pretreatment
Prior art date
Application number
AT96905630T
Other languages
English (en)
Inventor
Jacques Tremblay
Original Assignee
Univ Laval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Laval filed Critical Univ Laval
Application granted granted Critical
Publication of ATE412734T1 publication Critical patent/ATE412734T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96905630T 1995-03-16 1996-03-15 Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation ATE412734T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/404,888 US5833978A (en) 1995-03-16 1995-03-16 Method of in vitro preconditioning healthy donor's myoblasts before transplantation thereof in compatible patients suffering of recessive myopathies like muscular dystrophy, for improving transplantation success

Publications (1)

Publication Number Publication Date
ATE412734T1 true ATE412734T1 (de) 2008-11-15

Family

ID=23601451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96905630T ATE412734T1 (de) 1995-03-16 1996-03-15 Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation

Country Status (7)

Country Link
US (2) US5833978A (de)
EP (1) EP0815205B1 (de)
AT (1) ATE412734T1 (de)
AU (1) AU4934496A (de)
CA (1) CA2215244C (de)
DE (1) DE69637730D1 (de)
WO (1) WO1996028541A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410320B1 (en) 1992-03-02 2002-06-25 The University Of Michigan Method and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules
US20020164313A1 (en) * 1995-03-16 2002-11-07 Tremblay Jacques P. Compositions comprising preconditioned myoblasts having enhanced fusion properties
US6150164A (en) 1996-09-30 2000-11-21 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
US20020012657A1 (en) * 1996-10-18 2002-01-31 Jacques P. Tremblay Method for in vitro preconditioning of myoblasts before transplantation
AU741350B2 (en) * 1996-12-20 2001-11-29 Curis, Inc. Treatment of mammalian myocardium with morphogen locally, or with morphogenically-treated myogenic precursor cells
AU1864999A (en) * 1997-12-15 1999-07-05 Universite Laval Methods and compositions for improving the success of cell transplantation in a host
US20030113303A1 (en) * 1998-02-05 2003-06-19 Yitzhack Schwartz Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances
US20030129750A1 (en) * 1998-02-05 2003-07-10 Yitzhack Schwartz Homing of donor cells to a target zone in tissue using active therapeutics or substances
US7115417B1 (en) 1998-05-01 2006-10-03 Chancellor Michael B Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof
US6866842B1 (en) 1998-05-01 2005-03-15 University Of Pittsburgh Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
US6284242B1 (en) * 1999-04-16 2001-09-04 Regents Of The University Of Michigan Method for enhancing myoblast migration and invasion in the context of gene therapy
CA2386559A1 (en) * 1999-09-14 2001-03-22 The Children's Medical Center Corporation Isolation of muscle-derived stem cells and uses therefor
EP1272204B1 (de) * 2000-04-14 2007-06-20 University of Pittsburgh Vermehrung des weich- sowie des knochengewebes anhand von aus muskeln stammenden vorläuferzellen, sowie damit verbundene zusammensetzungen und behandlungsformen
US6538010B1 (en) * 2000-11-08 2003-03-25 Research Triangle Institute Compounds and methods for promoting smoking cessation
JP4680483B2 (ja) * 2001-02-23 2011-05-11 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組織および臓器の治療および修復に用いるための幹細胞マトリックスの迅速な調製方法
US7332330B2 (en) 2001-09-11 2008-02-19 Renamed Biologics, Inc. Device for maintaining vascularization near an implant
US7442546B2 (en) * 2002-03-15 2008-10-28 The Regents Of The University Of Michigan Method of modulating inflammatory response
WO2003085092A2 (en) * 2002-04-01 2003-10-16 Law Peter K Cellular transplantation for heart regeneration
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
CN1812800B (zh) * 2003-04-25 2013-01-16 匹兹堡大学 用于促进和增强神经修复和再生的肌肉来源的细胞(mdc)
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7828711B2 (en) 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US20060263338A1 (en) * 2005-03-04 2006-11-23 Jacoby Douglas B Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
AU2008205278B2 (en) * 2007-01-11 2014-06-12 University Of Pittsburgh Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same
WO2010022083A2 (en) * 2008-08-18 2010-02-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof
US20100233138A1 (en) * 2008-11-07 2010-09-16 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Vocal Cord Augmentation Utilizing Muscle-Derived Progenitor Compositions, and Treatments Thereof
US10273520B2 (en) 2013-04-03 2019-04-30 Wan Keung Raymond Wong Means and methods for hyper-production of authentic human basic fibroblast growth factor in Escherichia coli
WO2014161405A1 (en) * 2013-04-03 2014-10-09 Gene-Vinate Limited Means and method for expression of authentic human epidermal growth factor and/or basic fibrolast growth factor in cytoplasm and/or culture medium of escherichia coli
US10632305B2 (en) 2013-10-17 2020-04-28 University Of Maryland, Baltimore Methods of generating mature human muscle fibers
ES3039622T3 (en) 2016-03-04 2025-10-23 Univ Leland Stanford Junior Inhibitors of 15-hydroxyprostaglandin dehydrogenase for muscle regeneration
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
WO2018227134A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130141A (en) * 1988-05-24 1992-07-14 Law Peter K Compositions for and methods of treating muscle degeneration and weakness
US5143842A (en) * 1988-11-01 1992-09-01 The University Of Colorado Foundation, Inc. Media for normal human muscle satellite cells
ATE138267T1 (de) * 1989-11-24 1996-06-15 Univ Monash Proliferative wirkung des leukämie- hemmungsfaktors auf satellitzellen

Also Published As

Publication number Publication date
EP0815205B1 (de) 2008-10-29
CA2215244A1 (en) 1996-09-19
DE69637730D1 (de) 2008-12-11
AU4934496A (en) 1996-10-02
US20010051148A1 (en) 2001-12-13
US5833978A (en) 1998-11-10
CA2215244C (en) 2009-12-22
EP0815205A1 (de) 1998-01-07
WO1996028541A1 (en) 1996-09-19

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