ATE412907T1 - Verfahren zur messung von homocystein - Google Patents
Verfahren zur messung von homocysteinInfo
- Publication number
- ATE412907T1 ATE412907T1 AT04705917T AT04705917T ATE412907T1 AT E412907 T1 ATE412907 T1 AT E412907T1 AT 04705917 T AT04705917 T AT 04705917T AT 04705917 T AT04705917 T AT 04705917T AT E412907 T1 ATE412907 T1 AT E412907T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- reacting
- sample
- homocysteine
- measuring
- Prior art date
Links
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 title abstract 4
- 150000008574 D-amino acids Chemical class 0.000 abstract 7
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 4
- 102000004674 D-amino-acid oxidase Human genes 0.000 abstract 2
- 108010003989 D-amino-acid oxidase Proteins 0.000 abstract 2
- 102000005421 acetyltransferase Human genes 0.000 abstract 2
- 108020002494 acetyltransferase Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000016397 Methyltransferase Human genes 0.000 abstract 1
- 108060004795 Methyltransferase Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- -1 thiol compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
- G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003041585A JP2006149203A (ja) | 2003-02-19 | 2003-02-19 | ホモシステインの測定方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412907T1 true ATE412907T1 (de) | 2008-11-15 |
Family
ID=32905292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04705917T ATE412907T1 (de) | 2003-02-19 | 2004-01-28 | Verfahren zur messung von homocystein |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7135306B2 (de) |
| EP (1) | EP1595950B9 (de) |
| JP (2) | JP2006149203A (de) |
| AT (1) | ATE412907T1 (de) |
| CA (1) | CA2516029A1 (de) |
| DE (1) | DE602004017424D1 (de) |
| WO (1) | WO2004074477A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2085472B1 (de) | 2006-10-18 | 2013-08-21 | National University Corporation Nagoya University | D-serin-dehydratase und verwendung davon |
| CN101413878B (zh) * | 2008-12-16 | 2011-03-30 | 苏州艾杰生物科技有限公司 | 同型半胱氨酸的测定方法与同型半胱氨酸诊断/测定试剂盒 |
| US9216209B1 (en) | 2011-06-06 | 2015-12-22 | Kilmer S. McCully | Compositions and method for utilization of thioretinamide in therapy of degenerative diseases of aging |
| JP5751109B2 (ja) * | 2011-09-20 | 2015-07-22 | ニプロ株式会社 | 生体試料中の馬尿酸およびメチル馬尿酸のそれぞれの濃度を測定する方法 |
| ITRM20130317A1 (it) * | 2013-05-31 | 2014-12-01 | Uni Cattolica Del Sacro Cuor E | Metodo per la determinazione dell'omocisteina. |
| WO2016015060A1 (en) * | 2014-07-25 | 2016-01-28 | Bloodworks | Determination of small-molecule thiols and disulfides: protein bound cys and total cysteine as biomarkers of oxidative stress |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU676480B2 (en) * | 1992-01-22 | 1997-03-13 | Axis Biochemicals As | Homocysteine assay |
| US5478729A (en) * | 1994-04-28 | 1995-12-26 | Syntex (U.S.A.) Inc. | Immunoassay for homocysteine |
| GB9617683D0 (en) * | 1996-08-23 | 1996-10-02 | Univ Glasgow | Homocysteine desulphurase |
| US5985540A (en) * | 1997-07-24 | 1999-11-16 | Anticancer, Inc. | High specificity homocysteine assays for biological samples |
| TW546475B (en) * | 1998-12-07 | 2003-08-11 | Daiichi Pure Chemicals Co Ltd | A method for quantifying hydrogen sulfide or sulfide ion and a method for quantifying homocysteine or cysteine by using the method |
| JP2001017198A (ja) * | 1999-07-01 | 2001-01-23 | Toyobo Co Ltd | ホモシステインの測定方法およびホモシステイン測定用試薬組成物 |
| DE60131281T2 (de) * | 2000-06-30 | 2008-08-28 | Alfresa Pharma Corp. | Verfahren zum messen von gesamt-homocystein |
| US6867012B2 (en) | 2000-12-05 | 2005-03-15 | Toyo Boseki Kabushiki Kaisha | Determination method of biological component and reagent kit used therefor |
| JP4731733B2 (ja) * | 2001-06-07 | 2011-07-27 | 三菱化学メディエンス株式会社 | システイン共存試料中のホモシステインの測定法 |
| JP4008229B2 (ja) * | 2001-11-09 | 2007-11-14 | アルフレッサファーマ株式会社 | 安定なホモシステイン測定用組成物およびこれを用いるホモシステインの測定方法 |
-
2003
- 2003-02-19 JP JP2003041585A patent/JP2006149203A/ja not_active Withdrawn
-
2004
- 2004-01-28 WO PCT/JP2004/000787 patent/WO2004074477A1/ja not_active Ceased
- 2004-01-28 DE DE602004017424T patent/DE602004017424D1/de not_active Expired - Lifetime
- 2004-01-28 US US10/546,089 patent/US7135306B2/en not_active Expired - Fee Related
- 2004-01-28 EP EP04705917A patent/EP1595950B9/de not_active Expired - Lifetime
- 2004-01-28 AT AT04705917T patent/ATE412907T1/de not_active IP Right Cessation
- 2004-01-28 CA CA002516029A patent/CA2516029A1/en not_active Abandoned
- 2004-01-28 JP JP2005502669A patent/JPWO2004074477A1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1595950A4 (de) | 2007-03-07 |
| US7135306B2 (en) | 2006-11-14 |
| DE602004017424D1 (de) | 2008-12-11 |
| JPWO2004074477A1 (ja) | 2006-06-22 |
| EP1595950B1 (de) | 2008-10-29 |
| US20060166300A1 (en) | 2006-07-27 |
| EP1595950A1 (de) | 2005-11-16 |
| WO2004074477A1 (ja) | 2004-09-02 |
| EP1595950B9 (de) | 2009-06-10 |
| JP2006149203A (ja) | 2006-06-15 |
| CA2516029A1 (en) | 2004-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |