ATE310101T1 - Verfahren und kit zur erkennung von kinase aktivität - Google Patents

Verfahren und kit zur erkennung von kinase aktivität

Info

Publication number
ATE310101T1
ATE310101T1 AT01270619T AT01270619T ATE310101T1 AT E310101 T1 ATE310101 T1 AT E310101T1 AT 01270619 T AT01270619 T AT 01270619T AT 01270619 T AT01270619 T AT 01270619T AT E310101 T1 ATE310101 T1 AT E310101T1
Authority
AT
Austria
Prior art keywords
atp
tested
protein kinase
kit
kinase activity
Prior art date
Application number
AT01270619T
Other languages
English (en)
Inventor
Sharon Patricia Mary Crouch
Kevin John Slater
Original Assignee
Cambrex Bio Science Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9905234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE310101(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cambrex Bio Science Nottingham filed Critical Cambrex Bio Science Nottingham
Application granted granted Critical
Publication of ATE310101T1 publication Critical patent/ATE310101T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT01270619T 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität ATE310101T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0030727.2A GB0030727D0 (en) 2000-12-15 2000-12-15 Methods and kits for detecting kinase activity
PCT/GB2001/005506 WO2002048390A2 (en) 2000-12-15 2001-12-13 Methods and kits for detecting protein kinases

Publications (1)

Publication Number Publication Date
ATE310101T1 true ATE310101T1 (de) 2005-12-15

Family

ID=9905234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01270619T ATE310101T1 (de) 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität

Country Status (12)

Country Link
US (3) US6599711B2 (de)
EP (1) EP1341928B1 (de)
JP (1) JP3854927B2 (de)
AT (1) ATE310101T1 (de)
AU (1) AU2002222193A1 (de)
CA (1) CA2431274C (de)
CH (1) CH694096A5 (de)
DE (2) DE60115090T2 (de)
DK (1) DK1341928T3 (de)
ES (1) ES2256165T3 (de)
GB (2) GB0030727D0 (de)
WO (1) WO2002048390A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0030727D0 (en) 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity
JP5155515B2 (ja) 2002-09-06 2013-03-06 プロメガ コーポレイション トランスフェラーゼ酵素活性を検出する方法
US7799526B2 (en) 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
AU2003300008B2 (en) 2002-12-23 2007-04-05 Promega Corporation Improved luciferase-based assays
US7355010B2 (en) 2003-01-30 2008-04-08 Bellbrook Labs, Llc Assay method for group transfer reactions
US7378505B2 (en) * 2003-01-30 2008-05-27 Bellbrook Labs Llc Assay method for group transfer reactions
US8088897B2 (en) * 2003-01-30 2012-01-03 BellBrook Labs, Inc. Assay method for group transfer reactions
JP2006519013A (ja) * 2003-01-30 2006-08-24 ベル ブルック ラブズ リミテッド ライアビリティ カンパニー 基転移反応のアッセイ方法
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7619059B2 (en) 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
TW200526224A (en) * 2003-12-22 2005-08-16 Alcon Inc Short form c-Maf transcription factor antagonists for treatment of glaucoma
EP1696926A1 (de) * 2003-12-22 2006-09-06 Alcon, Inc. Mittel zur behandlung von diabetischer retinopathie und drusen-bildung bei makuladegeneration
BRPI0417987A (pt) * 2003-12-22 2007-04-27 Alcon Inc agentes para o tratamento de retinopatia glaucomatosa e de neuropatia óptica
WO2005069725A2 (en) 2004-01-16 2005-08-04 Mds Pharma Services Fluorescence-based adp detection system
WO2005075680A1 (ja) * 2004-02-09 2005-08-18 Fuso Pharmaceutical Industries, Ltd. 核酸検出方法およびその利用
US20080096238A1 (en) * 2004-03-30 2008-04-24 Alcon, Inc. High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio
WO2005102345A1 (en) * 2004-03-30 2005-11-03 Alcon, Inc. Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
US20060115870A1 (en) * 2004-03-30 2006-06-01 Alcon, Inc. High throughput assay for human Rho kinase activity
CN101040054A (zh) * 2004-07-02 2007-09-19 普罗美加公司 微生物atp提取及检测系统
WO2006055453A1 (en) * 2004-11-18 2006-05-26 Saladax Biomedical Inc. Enzymatic measurement of imatinib mesylate
US7338775B1 (en) 2005-02-09 2008-03-04 Myriad Genetics, Inc. Enzyme assay and use thereof
US20060234323A1 (en) * 2005-04-18 2006-10-19 Cali James J Luminescent ATP detection with extended linearity
US7348159B2 (en) * 2005-04-20 2008-03-25 Boehringer Ingelheim International Gmbh Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S
AU2006304838B2 (en) * 2005-10-21 2011-07-28 Deere & Company Systems and methods for obstacle avoidance
CA2642201C (en) 2006-02-13 2014-09-02 Olga Ornatsky Kinase and phosphatase assays conducted by elemental analysis
CN107573445B (zh) 2006-05-27 2021-05-25 富鲁达加拿大公司 聚合物骨架元素标签
KR100746961B1 (ko) 2006-07-31 2007-08-07 한국과학기술연구원 단백질 키나아제 ａ 검출용 바이오 센서, 및 이를 포함하는키트
US20080057531A1 (en) * 2006-08-07 2008-03-06 Oregon Health And Science University Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries
US7977043B2 (en) * 2006-11-10 2011-07-12 Boehringer Ingelheim International Gmbh Assays useful in determining CD38 inhibition
DE102006059881A1 (de) * 2006-12-19 2008-07-03 Sanofi-Aventis Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse
JP5753083B2 (ja) 2008-07-22 2015-07-22 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ Ａｄｐ検出に基づく発光ホスホトランスフェラーゼまたはａｔｐヒドロラーゼのアッセイ法
US20140080161A1 (en) * 2010-09-14 2014-03-20 Research And Diagnostic Systems, Inc. Phosphatase coupled kinase assay
GB201017721D0 (en) * 2010-10-20 2010-12-01 Queen Mary & Westfield College Method
NL2013366B1 (en) 2014-08-26 2016-09-23 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Adenylation enzyme inhibitors.
WO2016057084A1 (en) 2014-10-08 2016-04-14 Promega Corporation Bioluminescent succinate detection assay
JP6522556B2 (ja) * 2015-07-06 2019-05-29 富士フイルム株式会社 血液検査キット、及びそれを用いた分析方法
KR101788096B1 (ko) * 2016-04-12 2017-10-19 재단법인 한국파스퇴르연구소 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법
JP7414029B2 (ja) * 2021-02-26 2024-01-16 横河電機株式会社 測定方法及び測定システム

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE428379B (sv) * 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) * 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
DE2908054A1 (de) 1979-03-02 1980-09-11 Boehringer Mannheim Gmbh Verfahren und reagenz zur bestimmung der creatinkinase
SE7905852L (sv) * 1979-07-04 1981-01-05 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas
GB2055200B (en) * 1979-07-24 1984-05-02 Kolehmainen S Luminescent assays with enzymatic cycling enhancement of the sensitivity of bioluminescent and chemi
DE8533854U1 (de) * 1985-12-02 1986-02-27 Lewandoske, Herbert, 8620 Lichtenfels Sitzmöbel, insbesondere Sofa (und Sessel) mit abklappbaren Armlehnen
US5583024A (en) 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase
US4968613A (en) 1987-07-29 1990-11-06 Kikkoman Corporation Luciferase gene and novel recombinant DNA as well as a method of producing luciferase
US5219737A (en) 1990-03-27 1993-06-15 Kikkoman Corporation Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase
US5374534A (en) 1990-07-19 1994-12-20 Charm Sciences, Inc. Method of preparing D-luciferin derivatives
GB9301118D0 (en) 1993-01-21 1993-03-10 Secr Defence Enzyme linked assays
US5648232A (en) * 1993-01-21 1997-07-15 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Microbiological best method and reagents
ATE391769T1 (de) 1994-01-03 2008-04-15 Promega Corp Mutierte luziferasen
AU707243B2 (en) 1995-01-20 1999-07-08 Promega Corporation Mutant luciferases
JP3409962B2 (ja) * 1996-03-04 2003-05-26 キッコーマン株式会社 生物発光試薬及びその試薬を用いたアデノシンリン酸エステルの定量法並びにその試薬を用いたａｔｐ変換反応系に関与する物質の定量法
US5759795A (en) * 1996-03-08 1998-06-02 Schering Corporation Assay for determining inhibitors of ATPase
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US5759787A (en) * 1996-08-26 1998-06-02 Tularik Inc. Kinase assay
GB9626932D0 (en) 1996-12-24 1997-02-12 Lumitech Limited Assay methods and kits therefor
GB9707486D0 (en) 1997-04-11 1997-05-28 Secr Defence Enzyme assays
US6310060B1 (en) * 1998-06-24 2001-10-30 Warner-Lambert Company 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
US6074859A (en) 1997-07-08 2000-06-13 Kikkoman Corporation Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
DE69837612T2 (de) 1997-07-08 2007-12-27 Kikkoman Corp., Noda Mutiertes bioluminiszenz-protein und verfahren für seine herstellung.
WO1999037799A1 (en) 1998-01-21 1999-07-29 The Secretary Of State For Defence Antibiotic sensitivity testing
GB9803156D0 (en) 1998-02-13 1998-04-08 Celsis Int Plc Assay
NL1010224C2 (nl) 1998-09-30 2000-03-31 Packard Biosciene B V Werkwijze voor het detecteren van ATP.
DE19901427C1 (de) * 1999-01-18 2000-08-10 Walter Knoll Gmbh & Co Kg Sitz Sitzmöbel
GB9911095D0 (en) 1999-05-13 1999-07-14 Secr Defence Microbiological test method and reagents
GB0030727D0 (en) * 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity

Also Published As

Publication number Publication date
CA2431274C (en) 2011-05-17
GB2375171B (en) 2003-03-12
DE60115090T2 (de) 2006-07-13
DK1341928T3 (da) 2006-03-27
CA2431274A1 (en) 2002-06-20
CH694096A5 (de) 2004-07-15
US20020172991A1 (en) 2002-11-21
JP3854927B2 (ja) 2006-12-06
EP1341928A2 (de) 2003-09-10
US20040253658A1 (en) 2004-12-16
WO2002048390A3 (en) 2003-06-26
DE10196608T1 (de) 2003-07-31
GB2375171A (en) 2002-11-06
WO2002048390A2 (en) 2002-06-20
ES2256165T3 (es) 2006-07-16
US6599711B2 (en) 2003-07-29
DE60115090D1 (de) 2005-12-22
EP1341928B1 (de) 2005-11-16
JP2004518422A (ja) 2004-06-24
US6911319B2 (en) 2005-06-28
US20040077030A1 (en) 2004-04-22
GB0129889D0 (en) 2002-02-06
GB0030727D0 (en) 2001-01-31
AU2002222193A1 (en) 2002-06-24

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