ATE413862T1 - Stabilisierte natürliche cannabinoid formulierung - Google Patents

Stabilisierte natürliche cannabinoid formulierung

Info

Publication number
ATE413862T1
ATE413862T1 AT03730170T AT03730170T ATE413862T1 AT E413862 T1 ATE413862 T1 AT E413862T1 AT 03730170 T AT03730170 T AT 03730170T AT 03730170 T AT03730170 T AT 03730170T AT E413862 T1 ATE413862 T1 AT E413862T1
Authority
AT
Austria
Prior art keywords
sugar
natural cannabinoid
mixture
glass
drying
Prior art date
Application number
AT03730170T
Other languages
English (en)
Inventor
Anko Eissens
Drooge Dirk Van
Wouter Hinrichs
Henderik FRIJLINK
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Application granted granted Critical
Publication of ATE413862T1 publication Critical patent/ATE413862T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03730170T 2002-04-03 2003-04-02 Stabilisierte natürliche cannabinoid formulierung ATE413862T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36961302P 2002-04-03 2002-04-03
EP02076339 2002-04-04

Publications (1)

Publication Number Publication Date
ATE413862T1 true ATE413862T1 (de) 2008-11-15

Family

ID=28676390

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03730170T ATE413862T1 (de) 2002-04-03 2003-04-02 Stabilisierte natürliche cannabinoid formulierung

Country Status (16)

Country Link
EP (1) EP1492503B1 (de)
JP (1) JP4491241B2 (de)
CN (1) CN100592903C (de)
AT (1) ATE413862T1 (de)
AU (1) AU2003240759B2 (de)
BR (1) BR0308779A (de)
CA (1) CA2480270A1 (de)
DE (1) DE60324668D1 (de)
DK (1) DK1492503T3 (de)
ES (1) ES2316759T3 (de)
HR (1) HRP20040816A2 (de)
MX (1) MXPA04009673A (de)
NO (1) NO20044749L (de)
PL (1) PL209134B1 (de)
RU (1) RU2311178C2 (de)
WO (1) WO2003082246A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1428526A1 (de) * 2002-12-13 2004-06-16 Rijksuniversiteit Groningen Zusammensetzung zur schnellen Freisetzung von lipophilen Stoffen
DE10339197A1 (de) * 2003-08-22 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität
TW200621310A (en) * 2004-11-10 2006-07-01 Univ Groningen A process for preparing formulations of lypophilic active substances by spray freeze drying
GB0523638D0 (en) * 2005-11-21 2005-12-28 Cambridge Biostability Ltd Pharmaceutical device for the administration of substances to patients
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
BR112012024432A2 (pt) 2010-03-29 2016-05-31 Ferring Bv composição farmacêutica de dissolução rápida
JP6174585B2 (ja) 2011-09-16 2017-08-02 フェリング ベスローテン フェンノートシャップ 速溶性医薬組成物
US8741341B2 (en) * 2012-05-07 2014-06-03 Insys Therapeutics, Inc. Manufacturing and packaging room temperature stable dronabinol capsules
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
JP6953414B2 (ja) * 2016-01-20 2021-10-27 フラリー パウダーズ エルエルシーＦｌｕｒｒｙ Ｐｏｗｄｅｒｓ，Ｌｌｃ 親油性成分を含む吸入に好適な分散性の噴霧乾燥粉末を製造する方法
WO2019211772A1 (en) * 2018-05-03 2019-11-07 Radient Technologies Inc. Obtaining extracts in a solid form
CA3106476A1 (en) * 2018-07-10 2020-01-16 Cardinal Advisory Limited Formulation of cannabinoid compounds
CN110200953B (zh) * 2019-06-15 2022-02-08 汉义生物科技（北京）有限公司 大麻素在制备吸入给药药物中的应用
CA3128696C (en) * 2020-08-21 2023-09-26 Organigram Inc. Buccal dosage forms comprising oligosaccharides
WO2023224960A1 (en) * 2022-05-17 2023-11-23 Orcosa Inc. Rapidly infusing cannabinoid compositions, processes of manufacture, and methods of use
WO2023250274A1 (en) 2022-06-22 2023-12-28 Ilera Therapeutics Llc Enhanced capture and dissolution matrix for cannabinoids and methods of making the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
GB9010742D0 (en) * 1990-05-14 1990-07-04 Quadrant Bioresources Ltd Stabilization of biological macromolecular substances
US5955448A (en) * 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
IL117773A (en) * 1996-04-02 2000-10-31 Pharmos Ltd Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
US6509005B1 (en) * 1998-10-27 2003-01-21 Virginia Commonwealth University Δ9 Tetrahydrocannabinol (Δ9 THC) solution metered dose inhaler
NL1012300C2 (nl) * 1999-06-11 2000-12-12 Rijksuniversiteit Stabilisator voor farmaca.

Also Published As

Publication number Publication date
CA2480270A1 (en) 2003-10-09
CN1642527A (zh) 2005-07-20
NO20044749L (no) 2005-01-03
BR0308779A (pt) 2004-12-28
RU2311178C2 (ru) 2007-11-27
HK1078458A1 (zh) 2006-03-17
DE60324668D1 (de) 2008-12-24
PL209134B1 (pl) 2011-07-29
JP2005521710A (ja) 2005-07-21
DK1492503T3 (da) 2009-03-09
WO2003082246A1 (en) 2003-10-09
JP4491241B2 (ja) 2010-06-30
EP1492503B1 (de) 2008-11-12
AU2003240759B2 (en) 2008-02-14
CN100592903C (zh) 2010-03-03
EP1492503A1 (de) 2005-01-05
ES2316759T3 (es) 2009-04-16
MXPA04009673A (es) 2005-01-11
AU2003240759A1 (en) 2003-10-13
HRP20040816A2 (en) 2005-06-30
PL372921A1 (en) 2005-08-08
RU2004132190A (ru) 2005-04-20

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Legal Events

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