ATE414142T1 - Anti-ccr5 antikörper - Google Patents

Anti-ccr5 antikörper

Info

Publication number
ATE414142T1
ATE414142T1 AT03713632T AT03713632T ATE414142T1 AT E414142 T1 ATE414142 T1 AT E414142T1 AT 03713632 T AT03713632 T AT 03713632T AT 03713632 T AT03713632 T AT 03713632T AT E414142 T1 ATE414142 T1 AT E414142T1
Authority
AT
Austria
Prior art keywords
atcc deposit
deposit designation
plasmid designated
designation pta
ccr5
Prior art date
Application number
AT03713632T
Other languages
English (en)
Inventor
William Olson
Paul J Maddon
Maximiliano Vasquez
Paul Hinton
Naoya Tsurushita
Original Assignee
Progenics Pharm Inc
Pdl Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharm Inc, Pdl Biopharma Inc filed Critical Progenics Pharm Inc
Application granted granted Critical
Publication of ATE414142T1 publication Critical patent/ATE414142T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AT03713632T 2002-02-22 2003-02-21 Anti-ccr5 antikörper ATE414142T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8112802A 2002-02-22 2002-02-22

Publications (1)

Publication Number Publication Date
ATE414142T1 true ATE414142T1 (de) 2008-11-15

Family

ID=27765254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03713632T ATE414142T1 (de) 2002-02-22 2003-02-21 Anti-ccr5 antikörper

Country Status (19)

Country Link
EP (2) EP1478738B1 (de)
JP (1) JP2006508631A (de)
KR (1) KR20050004784A (de)
CN (1) CN1780907B (de)
AT (1) ATE414142T1 (de)
AU (1) AU2003217674C1 (de)
CA (1) CA2476901C (de)
CY (1) CY1108799T1 (de)
DE (1) DE60324664D1 (de)
DK (1) DK1478738T3 (de)
ES (1) ES2316740T3 (de)
IL (1) IL163655A0 (de)
MX (1) MXPA04008153A (de)
NO (1) NO20043971L (de)
NZ (2) NZ534947A (de)
PT (1) PT1478738E (de)
RU (1) RU2322454C2 (de)
WO (1) WO2003072766A1 (de)
ZA (1) ZA200406765B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
US7138119B2 (en) 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7060273B2 (en) 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
TW200720289A (en) 2005-04-01 2007-06-01 Hoffmann La Roche Antibodies against CCR5 and uses thereof
CA2616189C (en) * 2005-07-22 2019-03-26 Progenics Pharmaceuticals, Inc. Methods for reducing viral load in hiv-1-infected patients
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
EP2054086A1 (de) 2006-08-17 2009-05-06 F. Hoffmann-Roche AG Konjugat aus einem antikörper gegen ccr5 und einem antifusogenen peptid
CN101516914A (zh) 2006-09-29 2009-08-26 霍夫曼-拉罗奇有限公司 针对ccr5的抗体及其应用
US20090143288A1 (en) 2007-03-13 2009-06-04 Roche Palo Alto Llc Peptide-complement conjugates
JP2012502030A (ja) * 2008-09-05 2012-01-26 デューク ユニバーシティー 抗脂質抗体
NZ602685A (en) 2010-03-01 2014-10-31 Cytodyn Inc Concentrated protein formulations and uses thereof
WO2013024022A1 (en) 2011-08-12 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treatment of pulmonary hypertension
CN107847514A (zh) 2015-06-23 2018-03-27 西托戴恩股份有限公司 炎症、癌症、自身免疫和其它病症中ccl5配体结合ccr5受体的抑制作用和ccr5/ccl5轴信号传导的改变
US20180346571A1 (en) * 2015-11-17 2018-12-06 Oncomed Pharmaceuticals, Inc. Pd-l1-binding agents and uses thereof
AU2021207851A1 (en) * 2020-01-13 2022-07-14 Cytodyn Inc. CCR5 binding agent for treatment of CCR5 positive metastatic cancer
US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
JPH03505579A (ja) * 1988-06-30 1991-12-05 デービス，マイクル，エイチ ヒト免疫不全ウイルス（ｈｉｖ）のインビボにおける活性の阻害方法
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6165793A (en) 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same
US6458355B1 (en) 1998-01-22 2002-10-01 Genentech, Inc. Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates
US6258782B1 (en) 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
US6365408B1 (en) 1998-06-19 2002-04-02 Maxygen, Inc. Methods of evolving a polynucleotides by mutagenesis and recombination
CA2355607A1 (en) * 1998-12-16 2000-06-22 Progenics Pharmaceuticals, Inc. Anti-ccr5 antibody
JP3459386B2 (ja) 1999-10-15 2003-10-20 Ｓｍｃ株式会社 可逆式取付機構を有する流体圧機器
AU2841101A (en) * 1999-12-08 2001-06-18 Novartis Ag Methods and compositions useful for inhibiting ccr5-dependent infection of cellsby hiv-1
AU2265701A (en) * 1999-12-16 2001-06-25 Tanox, Inc. Anti-hiv-1 conjugates for treatment of hiv disease

Also Published As

Publication number Publication date
NZ561465A (en) 2009-04-30
DK1478738T3 (da) 2009-03-09
NZ534947A (en) 2008-03-28
AU2003217674A1 (en) 2003-09-09
EP2058006A1 (de) 2009-05-13
RU2004128252A (ru) 2005-04-10
NO20043971L (no) 2004-11-16
EP1478738B1 (de) 2008-11-12
HK1072272A1 (en) 2005-08-19
CA2476901A1 (en) 2003-09-04
RU2322454C2 (ru) 2008-04-20
CN1780907A (zh) 2006-05-31
AU2003217674C1 (en) 2009-03-26
PT1478738E (pt) 2009-02-16
IL163655A0 (en) 2005-12-18
DE60324664D1 (de) 2008-12-24
JP2006508631A (ja) 2006-03-16
MXPA04008153A (es) 2005-07-05
EP1478738A1 (de) 2004-11-24
CY1108799T1 (el) 2014-04-09
WO2003072766A1 (en) 2003-09-04
CN1780907B (zh) 2011-06-15
AU2003217674B2 (en) 2008-10-30
ZA200406765B (en) 2006-06-28
CA2476901C (en) 2012-10-09
ES2316740T3 (es) 2009-04-16
EP1478738A4 (de) 2006-05-31
KR20050004784A (ko) 2005-01-12

Similar Documents

Publication Publication Date Title
CY1108799T1 (el) Αντισωμα αντι- ccr5
CY1120070T1 (el) Μεθοδοi θεραπευτικης αγωγης με τη χρηση συζευγματων αντισωματος εναντι-erbb-μεϋτανσινοειδους
AR075790A2 (es) Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)
CY1110689T1 (el) Συνθεσεις οι οποιες περιλαμβανουν πολυπεπτιδια
LU92710I2 (fr) Ramucirumab et ses dérivés pharmaceutiquement acceptables (cyramza)
ATE187494T1 (de) Multivalente einkettige antikörper
NZ547157A (en) Interferon Alpha Antibodies and their uses
BR0315161A (pt) Anticorpo isolado, polinicleotìdeo isolado, vetor, célula hospedeira, método de produzir um anticorpo, e, composição
CO5160384A1 (es) Anticuerpo humanizado especifico para 4-1bb humano y composicion farmaceutica que comprende el mismo
ATE479710T1 (de) Bispezifische antikörper
CO4480111A1 (es) Anticuerpos monoclonales de mono especificos para humanos b7. y/o b7.2, formas primatizadas de los mismos, composicio- nes farmaceuticas que los contienen, y uso de los mismos co- mo inmunosupresantes
PT778891E (pt) Anticorpo monoclonal recombinante anti-rhesus d (d7c2)
FI4209510T3 (fi) Anti-PD-L1-vasta-aineita ja niiden käyttö T-solutoiminnan tehostamiseksi
GEP20094829B (en) Fully human antibodies against human 4-1bb (cd137)
CY1107708T1 (el) Ανθρωπινα μονοκλωνικα αντισωματα για υποδοχεα παραγοντα επιδερμικης αναπτυξης
DK1565489T3 (da) Internaliserende antistoffer specifikke for RAAG10-celleoverflademålet
ES2572177T3 (es) Anticuerpos neutralizantes anti-B7RP1 humanos
NZ590690A (en) Antibodies that bind to p-selectin glycoprotein ligand 1
AU628948B2 (en) Monoclonal antibodies (mabs) against tumor-associated antigens, the preparation and use thereof
FR2841905B1 (fr) Fragments fab mutants de l'anticorps anti-cd4 chimere 13b8.2 et leurs applications
WO2004050849A3 (en) Recombinant immunotoxin and use in treating tumors
NO930406D0 (no) Spesifikke antistoffer mot aktiverte blodplater samt fremstilling
CY1117275T1 (el) Μεθοδοι θεραπευτικης αγωγης με τη χρηση συζευγματων αντισωματος enanti-erbb-μεϊτανσινοειδους
TH83706A (th) แอนติ-5t4 แอนติบอดีที่ถูกฮิวมาไนซ์และคอนจูเกตของแอนติ-5t4 แอนติบอดี/คาลิซีอะไมซิน

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1478738

Country of ref document: EP

REN Ceased due to non-payment of the annual fee