ATE414780T1 - Methoden für gentransfer mit retroviren - Google Patents
Methoden für gentransfer mit retrovirenInfo
- Publication number
- ATE414780T1 ATE414780T1 AT03016618T AT03016618T ATE414780T1 AT E414780 T1 ATE414780 T1 AT E414780T1 AT 03016618 T AT03016618 T AT 03016618T AT 03016618 T AT03016618 T AT 03016618T AT E414780 T1 ATE414780 T1 AT E414780T1
- Authority
- AT
- Austria
- Prior art keywords
- target cells
- binding
- retroviruses
- gene transfer
- methods
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 abstract 3
- 241001430294 unidentified retrovirus Species 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13045—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/10—Vectors comprising a non-peptidic targeting moiety
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/851—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from growth factors; from growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18624098 | 1998-07-01 | ||
| JP5691599 | 1999-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE414780T1 true ATE414780T1 (de) | 2008-12-15 |
Family
ID=26397921
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03016618T ATE414780T1 (de) | 1998-07-01 | 1999-06-25 | Methoden für gentransfer mit retroviren |
| AT99926821T ATE350482T1 (de) | 1998-07-01 | 1999-06-25 | Gentransfermethoden |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926821T ATE350482T1 (de) | 1998-07-01 | 1999-06-25 | Gentransfermethoden |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6787359B1 (de) |
| EP (2) | EP1362918B8 (de) |
| JP (1) | JP3807937B2 (de) |
| KR (1) | KR100608154B1 (de) |
| CN (1) | CN1190496C (de) |
| AT (2) | ATE414780T1 (de) |
| AU (1) | AU4393899A (de) |
| DE (2) | DE69934690T2 (de) |
| ES (2) | ES2277438T3 (de) |
| WO (1) | WO2000001836A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6551843B1 (en) * | 1999-01-29 | 2003-04-22 | Immunivest Corporation | Methods for enhancing binding interactions between members of specific binding pairs |
| CN1225285C (zh) * | 1999-03-23 | 2005-11-02 | 宝生物工程株式会社 | 基因治疗剂 |
| JP2005052001A (ja) * | 2001-07-05 | 2005-03-03 | Takara Bio Inc | 遺伝子治療剤 |
| US20100144038A1 (en) * | 2003-03-04 | 2010-06-10 | Masato Miyake | Composition And Method For Increasing Efficiency Of Introduction Of Target Substance Into Cell |
| WO2005001090A1 (ja) * | 2003-06-26 | 2005-01-06 | National Institute Of Advanced Industrial Science And Technology | 細胞の核酸導入効率を改善する方法および組成物 |
| EP1715052A4 (de) * | 2004-01-29 | 2007-10-03 | Nat Inst Of Advanced Ind Scien | Zusammensetzung und verfahren zur erhöhung der gentransfereffizienz |
| CN101031651B (zh) * | 2004-09-29 | 2010-06-16 | 宝生物工程株式会社 | 用于产生反转录病毒载体的细胞 |
| CN101115830B (zh) * | 2005-02-07 | 2012-09-05 | 宝生物工程株式会社 | 逆转录病毒储存方法 |
| JP4860612B2 (ja) * | 2005-06-15 | 2012-01-25 | タカラバイオ株式会社 | 脂肪細胞あるいは前駆脂肪細胞への遺伝子導入方法 |
| JP5453629B2 (ja) | 2006-08-23 | 2014-03-26 | タカラバイオ株式会社 | 遠心用袋状容器を使用した遺伝子導入方法 |
| AU2007294731B2 (en) | 2006-09-13 | 2014-04-17 | Abbvie Inc. | Cell culture improvements |
| CN102144027B (zh) * | 2008-07-07 | 2016-04-06 | 宝生物工程株式会社 | 生产多能干细胞的方法 |
| WO2011024791A1 (ja) | 2009-08-25 | 2011-03-03 | タカラバイオ株式会社 | レチノイン酸存在下でのｔ細胞集団の製造方法 |
| US9228206B2 (en) | 2010-06-30 | 2016-01-05 | Takara Bio Inc. | Method for gene transfer |
| WO2012002452A1 (ja) * | 2010-06-30 | 2012-01-05 | タカラバイオ株式会社 | 遺伝子導入方法 |
| CN103124787B (zh) | 2010-10-05 | 2015-04-29 | 宝生物工程株式会社 | 制造病毒载体的方法 |
| WO2013051718A1 (ja) | 2011-10-07 | 2013-04-11 | 国立大学法人三重大学 | キメラ抗原受容体 |
| JP6014119B2 (ja) * | 2012-03-22 | 2016-10-25 | タカラバイオ株式会社 | ウイルスベクターの製造方法 |
| WO2017024318A1 (en) | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| US11052111B2 (en) | 2015-12-08 | 2021-07-06 | Chimera Bioengineering, Inc. | Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses |
| CN112481217A (zh) | 2016-09-01 | 2021-03-12 | 嵌合体生物工程公司 | Gold优化的car t-细胞 |
| US11524988B2 (en) * | 2016-09-19 | 2022-12-13 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Artificial antigen presenting cells for genetic engineering of immune cells |
| JP7227912B2 (ja) | 2017-02-08 | 2023-02-24 | ダナ－ファーバー キャンサー インスティテュート，インコーポレイテッド | キメラ抗原受容体の調節 |
| WO2018156735A1 (en) | 2017-02-22 | 2018-08-30 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Bispecific antibody for cancer immunotherapy |
| US20220372516A1 (en) | 2019-10-11 | 2022-11-24 | Takara Bio Inc. | siRNA EXPRESSION VECTOR |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9014294D0 (en) * | 1990-06-27 | 1990-08-15 | Medical Res Council | Assay for cytotoxic t cells |
| JPH05252941A (ja) | 1991-08-12 | 1993-10-05 | Sakai Enetsukusu Kk | 動物細胞培養用担体 |
| NL9101680A (nl) * | 1991-10-04 | 1993-05-03 | Tno | Werkwijze voor het genetisch modificeren van beenmergcellen van primaten, alsmede daarbij bruikbare cellen die recombinante retrovirale vectoren produceren. |
| US5656456A (en) | 1992-07-13 | 1997-08-12 | Bionebraska, Inc. | Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof |
| JPH08504098A (ja) * | 1992-11-20 | 1996-05-07 | ユニバーシティー オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 抗体−エンベロープ融合蛋白を含有するレトロウィルスベクターを用いた細胞種特異的な遺伝子転移 |
| US6013628A (en) * | 1994-02-28 | 2000-01-11 | Regents Of The University Of Minnesota | Method for treating conditions of the eye using polypeptides |
| US5686278A (en) | 1994-03-25 | 1997-11-11 | Indiana University Foundation | Methods for enhanced retrovirus-mediated gene transfer |
| JPH08317785A (ja) * | 1995-03-17 | 1996-12-03 | Kanagawa Kagaku Gijutsu Akad | 糖鎖の固定化法及びそれを用いた細胞培養基材 |
| JP3867160B2 (ja) * | 1995-07-03 | 2007-01-10 | 大日本住友製薬株式会社 | 遺伝子製剤 |
| IL122802A0 (en) | 1995-07-03 | 1998-08-16 | Koken Kk | Gene preparations |
| ATE325533T1 (de) | 1995-09-29 | 2006-06-15 | Univ Indiana Res & Tech Corp | Verfahren zum verbesserten virusvermittelten dns- transfer unter verwendung von molekülen mit virus-und zellbindenden domänen |
| KR100353115B1 (ko) * | 1995-11-13 | 2003-01-06 | 다카라츠죠 가부시키가이샤 | 레트로바이러스를사용한표적세포내로의유전자도입방법 |
| CA2217266A1 (en) * | 1997-05-14 | 1998-11-14 | The General Hospital Corporation | Co-cultivation of cells in a micropatterned configuration |
-
1999
- 1999-06-25 ES ES99926821T patent/ES2277438T3/es not_active Expired - Lifetime
- 1999-06-25 WO PCT/JP1999/003403 patent/WO2000001836A1/ja not_active Ceased
- 1999-06-25 DE DE69934690T patent/DE69934690T2/de not_active Expired - Lifetime
- 1999-06-25 EP EP03016618A patent/EP1362918B8/de not_active Expired - Lifetime
- 1999-06-25 CN CNB99810079XA patent/CN1190496C/zh not_active Expired - Fee Related
- 1999-06-25 AT AT03016618T patent/ATE414780T1/de not_active IP Right Cessation
- 1999-06-25 AT AT99926821T patent/ATE350482T1/de not_active IP Right Cessation
- 1999-06-25 KR KR1020007013820A patent/KR100608154B1/ko not_active Expired - Lifetime
- 1999-06-25 EP EP99926821A patent/EP1094114B1/de not_active Expired - Lifetime
- 1999-06-25 JP JP2000558226A patent/JP3807937B2/ja not_active Expired - Lifetime
- 1999-06-25 ES ES03016618T patent/ES2316675T3/es not_active Expired - Lifetime
- 1999-06-25 US US09/743,354 patent/US6787359B1/en not_active Expired - Lifetime
- 1999-06-25 DE DE69939955T patent/DE69939955D1/de not_active Expired - Lifetime
- 1999-06-25 AU AU43938/99A patent/AU4393899A/en not_active Abandoned
-
2003
- 2003-09-09 US US10/657,076 patent/US20040058447A1/en not_active Abandoned
-
2007
- 2007-07-27 US US11/829,313 patent/US20080044903A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1362918B8 (de) | 2009-08-05 |
| US20040058447A1 (en) | 2004-03-25 |
| JP3807937B2 (ja) | 2006-08-09 |
| DE69939955D1 (de) | 2009-01-02 |
| ES2277438T3 (es) | 2007-07-01 |
| ES2316675T3 (es) | 2009-04-16 |
| EP1094114A1 (de) | 2001-04-25 |
| US20080044903A1 (en) | 2008-02-21 |
| EP1094114A4 (de) | 2002-10-30 |
| EP1362918A1 (de) | 2003-11-19 |
| DE69934690T2 (de) | 2007-11-15 |
| EP1362918B1 (de) | 2008-11-19 |
| ATE350482T1 (de) | 2007-01-15 |
| AU4393899A (en) | 2000-01-24 |
| DE69934690D1 (de) | 2007-02-15 |
| CN1314947A (zh) | 2001-09-26 |
| WO2000001836A1 (en) | 2000-01-13 |
| US6787359B1 (en) | 2004-09-07 |
| KR20010071422A (ko) | 2001-07-28 |
| EP1094114B1 (de) | 2007-01-03 |
| KR100608154B1 (ko) | 2006-08-04 |
| CN1190496C (zh) | 2005-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |