ATE415420T1 - Cxcl8-antagonisten - Google Patents

Cxcl8-antagonisten

Info

Publication number: ATE415420T1
Authority: AT; Austria
Prior art keywords: cxcl8; antagonists; interleukin; vivo; prevention
Prior art date: 2003-10-22

Application number

AT04791294T

Other languages

English (en)

Inventor

Amanda Proudfoot

Jeffrey Shaw

Original Assignee

Serono Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-22

Filing date

2004-10-22

Publication date

2008-12-15

2004-10-22 Application filed by Serono Lab filed Critical Serono Lab

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE415420T1 publication Critical patent/ATE415420T1/de

Links

101001055222 Homo sapiens Interleukin-8 Proteins 0.000 title abstract 3
102100026236 Interleukin-8 Human genes 0.000 title abstract 3
239000005557 antagonist Substances 0.000 title abstract 2
102000004890 Interleukin-8 Human genes 0.000 abstract 2
108090001007 Interleukin-8 Proteins 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 1
210000004899 c-terminal region Anatomy 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 abstract 1
229940096397 interleukin-8 Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5421—IL-8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT04791294T 2003-10-22 2004-10-22 Cxcl8-antagonisten ATE415420T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP03103909		2003-10-22

Publications (1)

Publication Number	Publication Date
ATE415420T1 true ATE415420T1 (de)	2008-12-15

Family

ID=34486342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04791294T ATE415420T1 (de)	2003-10-22	2004-10-22	Cxcl8-antagonisten

Country Status (10)

Country	Link
US (1)	US20090022657A1 (de)
EP (1)	EP1673388B1 (de)
JP (1)	JP2007533300A (de)
AT (1)	ATE415420T1 (de)
AU (1)	AU2004283910A1 (de)
CA (1)	CA2534828A1 (de)
DE (1)	DE602004018014D1 (de)
IL (1)	IL175019A0 (de)
NO (1)	NO20062316L (de)
WO (1)	WO2005040210A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2019143566A1 (en) *	2018-01-18	2019-07-25	Third Wave Bioactives, Llc	Fruit and vegetable-based fermentate compositions and methods of making and using the same
TR201811689A2 (tr) *	2018-08-10	2018-09-21	Hacettepe Ueniversitesi	Cxcl8 ami̇no ucu öncül di̇zi̇si̇nden türevlenen i̇mmünmodülatör pepti̇t

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69226649D1 (de) *	1991-12-04	1998-09-17	Biomedical Research Centre Ltd	Analoge des menschlichen Interleukin-8.
AU3681795A (en) *	1994-09-23	1996-04-09	University Of Nebraska Board Of Regents	Polypeptide agonists and antagonists of human interleukin-8
UA77950C2 (en) *	2000-10-04	2007-02-15	Applied Research Systems	Use of mutants of cc chemokines for treatment of multiple sclerosis

2004
- 2004-10-22 US US10/573,726 patent/US20090022657A1/en not_active Abandoned
- 2004-10-22 WO PCT/EP2004/052637 patent/WO2005040210A2/en not_active Ceased
- 2004-10-22 AT AT04791294T patent/ATE415420T1/de not_active IP Right Cessation
- 2004-10-22 JP JP2006536095A patent/JP2007533300A/ja active Pending
- 2004-10-22 CA CA002534828A patent/CA2534828A1/en not_active Abandoned
- 2004-10-22 DE DE602004018014T patent/DE602004018014D1/de not_active Expired - Fee Related
- 2004-10-22 EP EP04791294A patent/EP1673388B1/de not_active Expired - Lifetime
- 2004-10-22 AU AU2004283910A patent/AU2004283910A1/en not_active Abandoned
2006
- 2006-04-20 IL IL175019A patent/IL175019A0/en unknown
- 2006-05-22 NO NO20062316A patent/NO20062316L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2004283910A1 (en)	2005-05-06
WO2005040210A3 (en)	2005-06-23
US20090022657A1 (en)	2009-01-22
CA2534828A1 (en)	2005-05-06
JP2007533300A (ja)	2007-11-22
NO20062316L (no)	2006-06-23
EP1673388A2 (de)	2006-06-28
EP1673388B1 (de)	2008-11-26
IL175019A0 (en)	2006-08-20
DE602004018014D1 (de)	2009-01-08
WO2005040210A2 (en)	2005-05-06

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Legal Events

Date	Code	Title	Description
2009-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties