ATE415623T1 - Verfahren und vorrichtung zur messung der aktivierung von neutrophilen zellen - Google Patents
Verfahren und vorrichtung zur messung der aktivierung von neutrophilen zellenInfo
- Publication number
- ATE415623T1 ATE415623T1 AT05714373T AT05714373T ATE415623T1 AT E415623 T1 ATE415623 T1 AT E415623T1 AT 05714373 T AT05714373 T AT 05714373T AT 05714373 T AT05714373 T AT 05714373T AT E415623 T1 ATE415623 T1 AT E415623T1
- Authority
- AT
- Austria
- Prior art keywords
- mpo
- cells
- sample
- levels
- active
- Prior art date
Links
- 210000000440 neutrophil Anatomy 0.000 title abstract 9
- 230000004913 activation Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000003896 Myeloperoxidases Human genes 0.000 abstract 52
- 108090000235 Myeloperoxidases Proteins 0.000 abstract 52
- 239000000523 sample Substances 0.000 abstract 9
- 230000000694 effects Effects 0.000 abstract 8
- 210000004027 cell Anatomy 0.000 abstract 7
- 239000012472 biological sample Substances 0.000 abstract 6
- 230000020411 cell activation Effects 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 5
- 241000283086 Equidae Species 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 4
- 238000001514 detection method Methods 0.000 abstract 4
- 238000005259 measurement Methods 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 230000001900 immune effect Effects 0.000 abstract 3
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- PKYCWFICOKSIHZ-UHFFFAOYSA-N 1-(3,7-dihydroxyphenoxazin-10-yl)ethanone Chemical compound OC1=CC=C2N(C(=O)C)C3=CC=C(O)C=C3OC2=C1 PKYCWFICOKSIHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000002965 ELISA Methods 0.000 abstract 1
- 238000008157 ELISA kit Methods 0.000 abstract 1
- 102000003992 Peroxidases Human genes 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 108040007629 peroxidase activity proteins Proteins 0.000 abstract 1
- 239000012429 reaction media Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04447027 | 2004-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE415623T1 true ATE415623T1 (de) | 2008-12-15 |
Family
ID=34833847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05714373T ATE415623T1 (de) | 2004-02-06 | 2005-02-07 | Verfahren und vorrichtung zur messung der aktivierung von neutrophilen zellen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8399208B2 (de) |
| EP (1) | EP1711817B1 (de) |
| AT (1) | ATE415623T1 (de) |
| CA (1) | CA2554899C (de) |
| DE (2) | DE202005020939U1 (de) |
| ES (1) | ES2318459T3 (de) |
| NZ (1) | NZ548816A (de) |
| WO (1) | WO2005075986A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008144850A1 (en) * | 2007-05-30 | 2008-12-04 | Advanced Diagnostic Systems Ltd | Assay for determining risk of development of allergic disorders |
| EP2017351B1 (de) * | 2007-07-20 | 2010-10-27 | Université de Liège | Kombination aus Verfahren zur sequentiellen Messung (1.) der enzymatisch aktiven Fraktion und (2.) der Gesamtmenge eines Enzyms |
| US20090053747A1 (en) * | 2007-08-21 | 2009-02-26 | Mattingly Phillip G | Measurement of Haloperoxidase Activity With Chemiluminescent Detection |
| US20090162876A1 (en) * | 2007-12-20 | 2009-06-25 | Abbott Laboratories | Myeloperoxidase assays |
| ES2554231T3 (es) * | 2011-05-19 | 2015-12-17 | Baxalta Incorporated | Detección de complejos de ADAMTS13-anticuerpo en circulación |
| CN102680676B (zh) * | 2011-07-29 | 2015-06-10 | 南京诺尔曼生物技术有限公司 | 髓过氧化物酶(myeloperoxidase MPO)测定试剂盒(胶乳增强免疫比浊法) |
| CA2878094A1 (en) * | 2012-06-27 | 2014-01-03 | Siscapa Assay Technologies, Inc. | Multipurpose mass spectrometric assay panels for peptides |
| CN103727992B (zh) * | 2013-11-11 | 2016-02-10 | 鲁东大学 | 一种测量氧灌水气出流均匀度的系统与方法 |
| CN103604476B (zh) * | 2013-11-11 | 2016-02-10 | 鲁东大学 | 一种测量水气耦合滴灌水气出流量的系统与方法 |
| CN104730019B (zh) * | 2015-04-08 | 2017-04-19 | 安徽中烟工业有限责任公司 | 一种体外评价卷烟及烟草安全性的方法 |
| CN106908601B (zh) * | 2017-03-06 | 2019-02-12 | 海格德生物科技（深圳）有限公司 | 人髓过氧化物酶活性及总量检测试剂盒及检测方法和制备方法 |
| CN108445215A (zh) * | 2018-02-01 | 2018-08-24 | 浙江艾明德生物科技有限公司 | 一种定量检测髓过氧化物酶的试剂盒及制备方法 |
| EP3904876A1 (de) * | 2020-04-28 | 2021-11-03 | Universitat Politècnica De Catalunya | Faltbare fluidische vorrichtung und verfahren zur biomarkendetektion in körperflüssigkeiten |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5460961A (en) * | 1988-06-14 | 1995-10-24 | La Region Wallonne | Human myeloperoxidase and its therapeutic application |
| JP2614155B2 (ja) * | 1991-06-18 | 1997-05-28 | 株式会社三和化学研究所 | ヒト顆粒球エラスターゼの免疫学的測定方法 |
| US5552292A (en) * | 1993-01-18 | 1996-09-03 | Ikagaku Co., Ltd. | Method of screening for colorectal cancer |
| US5698518A (en) * | 1994-03-30 | 1997-12-16 | Oklahoma Medical Research Foundation | Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists |
| GB9811414D0 (en) | 1998-05-28 | 1998-07-22 | Imp College Innovations Ltd | Method of measuring enzyme activity |
| BE1013881A6 (fr) | 2000-12-21 | 2002-11-05 | Univ Bruxelles | Fractions de ldl oxydees, procede d'obtention et utilisation a but diagnostique ou therapeutique. |
| GB0318110D0 (en) * | 2003-08-01 | 2003-09-03 | Isaeo Ltd | Methods and kits for detecting an enzyme capable of modifying a nucleic acid |
| EP2017351B1 (de) * | 2007-07-20 | 2010-10-27 | Université de Liège | Kombination aus Verfahren zur sequentiellen Messung (1.) der enzymatisch aktiven Fraktion und (2.) der Gesamtmenge eines Enzyms |
-
2005
- 2005-02-07 AT AT05714373T patent/ATE415623T1/de not_active IP Right Cessation
- 2005-02-07 ES ES05714373T patent/ES2318459T3/es not_active Expired - Lifetime
- 2005-02-07 CA CA2554899A patent/CA2554899C/en not_active Expired - Fee Related
- 2005-02-07 US US10/597,636 patent/US8399208B2/en not_active Expired - Fee Related
- 2005-02-07 DE DE202005020939U patent/DE202005020939U1/de not_active Expired - Lifetime
- 2005-02-07 DE DE602005011250T patent/DE602005011250D1/de not_active Expired - Lifetime
- 2005-02-07 NZ NZ548816A patent/NZ548816A/en not_active IP Right Cessation
- 2005-02-07 EP EP05714373A patent/EP1711817B1/de not_active Expired - Lifetime
- 2005-02-07 WO PCT/BE2005/000017 patent/WO2005075986A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20080233600A1 (en) | 2008-09-25 |
| WO2005075986A2 (en) | 2005-08-18 |
| DE602005011250D1 (de) | 2009-01-08 |
| EP1711817A2 (de) | 2006-10-18 |
| US8399208B2 (en) | 2013-03-19 |
| CA2554899C (en) | 2013-01-29 |
| NZ548816A (en) | 2009-12-24 |
| WO2005075986A3 (en) | 2006-01-26 |
| CA2554899A1 (en) | 2005-08-18 |
| ES2318459T3 (es) | 2009-05-01 |
| DE202005020939U1 (de) | 2007-03-08 |
| EP1711817B1 (de) | 2008-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |