ATE417068T1 - Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin - Google Patents

Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin

Info

Publication number: ATE417068T1
Authority: AT; Austria
Prior art keywords: von willebrand; willebrand factor; binding; glycoprotein; glycocallidin
Prior art date: 1998-04-23

Application number

AT99900301T

Other languages

English (en)

Inventor

Naoyuki Fukuchi

Fumie Futaki

Morikazu Kito

Seiichi Sato

Takayuki Kajiura

Yukitsugu Ono

Koichi Ishii

Akiko Tanaka

Junko Shinozaki

Yasuko Jojima

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-23

Filing date

1999-01-13

Publication date

2008-12-15

1999-01-13 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE417068T1 publication Critical patent/ATE417068T1/de

Links

238000000034 method Methods 0.000 title abstract 2
230000002785 anti-thrombosis Effects 0.000 title 1
239000000126 substance Substances 0.000 title 1
108010047303 von Willebrand Factor Proteins 0.000 abstract 4
102100036537 von Willebrand factor Human genes 0.000 abstract 4
229960001134 von willebrand factor Drugs 0.000 abstract 4
102000023159 Platelet Glycoprotein GPIb-IX Complex Human genes 0.000 abstract 3
108010045766 Platelet Glycoprotein GPIb-IX Complex Proteins 0.000 abstract 3
108060003951 Immunoglobulin Proteins 0.000 abstract 2
102000018358 immunoglobulin Human genes 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
102000037865 fusion proteins Human genes 0.000 abstract 1
108020001507 fusion proteins Proteins 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/755—Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Zoology (AREA)
Toxicology (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Peptides Or Proteins (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

AT99900301T 1998-04-23 1999-01-13 Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin ATE417068T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP11396298		1998-04-23

Publications (1)

Publication Number	Publication Date
ATE417068T1 true ATE417068T1 (de)	2008-12-15

Family

ID=14625575

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99900301T ATE417068T1 (de)	1998-04-23	1999-01-13	Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin

Country Status (6)

Country	Link
US (3)	US6878811B1 (de)
EP (1)	EP1074564B1 (de)
JP (2)	JP4380067B2 (de)
AT (1)	ATE417068T1 (de)
DE (1)	DE69940058D1 (de)
WO (1)	WO1999054360A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1074564B1 (de) *	1998-04-23	2008-12-10	Ajinomoto Co., Inc.	Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin
AR035779A1 (es) *	2001-02-06	2004-07-14	Genetics Inst Llc	Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos
US7235558B2 (en)	2002-06-06	2007-06-26	Sanofi-Aventis Deutschland Gmbh	Inhibitors of the GPIb—vWF interaction, their preparation and use
BRPI0411289A (pt)	2003-06-11	2006-08-01	Wyeth Corp	polipeptìdeos de fusão da variante da glicoproteìna ib alfa de plaquetas e métodos do seu uso
US7780831B2 (en)	2003-07-07	2010-08-24	The University Of North Carolina At Chapel Hill	Assays for detection of von willebrand factor (vWF) multimers and for degradation of vWF by agents such as ADAMTS13 and related methods
JP2005073528A (ja) *	2003-08-28	2005-03-24	Genetics Inst Llc	生物学的系における生物学的組織への血球の接着を阻害する方法、ならびにその方法に使用するための組成物
AU2006239939A1 (en) *	2005-04-22	2006-11-02	Wyeth	Method for determination of glycoprotein ibalpha (GPibalpha) protein
CN102427823A (zh) *	2009-03-24	2012-04-25	拜耳医药保健有限公司	因子viii变体及使用方法
EP2431739A1 (de) *	2010-09-21	2012-03-21	Sanofi	Verfahren zur Erkennung und/oder Quantifizierung der Interaktion von Plättchen mit Interaktionspartnern
EP2637024A1 (de)	2012-03-05	2013-09-11	Siemens Healthcare Diagnostics Products GmbH	Screeningverfahren zum Auffinden von Proben mit einer Störung der Funktionalität der GPIb-Von Willebrand Faktor-Interaktion
EP3555123B1 (de)	2018-02-20	2024-03-27	F. Hoffmann-La Roche AG	Zusammensetzung mit rekombinantem gpiba-rezeptorprotein

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4444879A (en) *	1981-01-29	1984-04-24	Science Research Center, Inc.	Immunoassay with article having support film and immunological counterpart of analyte
US5340727A (en)	1987-11-17	1994-08-23	The Scripps Research Institute	GPIbα fragments and recombinant DNA expression vectors
US5321127A (en) *	1991-03-18	1994-06-14	Brigham And Women's Hospital	Antiplatelet and antithrombotic activity of platelet glycoprotein Ib receptor fragments
AU3734793A (en) *	1992-02-26	1993-09-13	Scripps Research Institute, The	Mutant gpibalpha fragments and recombinant expression thereof
US5585243A (en) *	1993-09-15	1996-12-17	The Blood Center Of Southeastern Wisconsin, Inc.	Method of detecting cytopenia that is mediated by drug-dependent antibody binding to blood cells
KR960704931A (ko) *	1993-09-28	1996-10-09	이나모리 슌스케	펩타이드 및 항혈전제(Peptide and antithrombotic agent)
JPH07330797A (ja) *	1994-05-31	1995-12-19	Sumitomo Metal Ind Ltd	新規細胞接着活性ペプチド
EP1621206A1 (de)	1994-12-12	2006-02-01	Beth Israel Deaconess Medical Center, Inc.	Chimäre Zytokine und ihre Verwendung
JPH08333400A (ja)	1995-06-09	1996-12-17	Ajinomoto Co Inc	抗血栓活性を有する融合蛋白質及びその製法
SE504496C2 (sv) *	1995-07-03	1997-02-24	Stromsholmens Mek Verkstad	Anordning vid en gasfjäder för avstrykning av en kolvstång
US6369027B1 (en) *	1995-12-22	2002-04-09	Amgen Inc.	Osteoprotegerin
RU2178307C2 (ru)	1995-12-27	2002-01-20	Джинентех Инк.	Производные ов-протеина
US6790823B1 (en) *	1998-04-23	2004-09-14	Amgen Inc.	Compositions and methods for the prevention and treatment of cardiovascular diseases
EP1074564B1 (de) *	1998-04-23	2008-12-10	Ajinomoto Co., Inc.	Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin

1999
- 1999-01-13 EP EP99900301A patent/EP1074564B1/de not_active Expired - Lifetime
- 1999-01-13 US US09/673,245 patent/US6878811B1/en not_active Expired - Fee Related
- 1999-01-13 DE DE69940058T patent/DE69940058D1/de not_active Expired - Lifetime
- 1999-01-13 WO PCT/JP1999/000089 patent/WO1999054360A1/ja not_active Ceased
- 1999-01-13 JP JP2000544698A patent/JP4380067B2/ja not_active Expired - Fee Related
- 1999-01-13 AT AT99900301T patent/ATE417068T1/de not_active IP Right Cessation
2004
- 2004-04-16 US US10/825,127 patent/US7608695B2/en not_active Expired - Fee Related
2008
- 2008-05-15 JP JP2008128186A patent/JP2008224684A/ja active Pending
2009
- 2009-08-27 US US12/548,898 patent/US20100120172A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69940058D1 (de)	2009-01-22
US7608695B2 (en)	2009-10-27
US6878811B1 (en)	2005-04-12
EP1074564B1 (de)	2008-12-10
WO1999054360A1 (en)	1999-10-28
WO1999054360A8 (en)	1999-12-29
EP1074564A4 (de)	2004-10-27
US20100120172A1 (en)	2010-05-13
EP1074564A1 (de)	2001-02-07
JP2008224684A (ja)	2008-09-25
US20040229288A1 (en)	2004-11-18
JP4380067B2 (ja)	2009-12-09

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Legal Events

Date	Code	Title	Description
2009-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties