ATE417116T1 - Chromosomstellen zur stringenten kontrolle von genaktivität durch transkriptionsteuersysteme - Google Patents

Chromosomstellen zur stringenten kontrolle von genaktivität durch transkriptionsteuersysteme

Info

Publication number
ATE417116T1
ATE417116T1 AT03790868T AT03790868T ATE417116T1 AT E417116 T1 ATE417116 T1 AT E417116T1 AT 03790868 T AT03790868 T AT 03790868T AT 03790868 T AT03790868 T AT 03790868T AT E417116 T1 ATE417116 T1 AT E417116T1
Authority
AT
Austria
Prior art keywords
gene activity
chromosome site
control systems
meo
transcription
Prior art date
Application number
AT03790868T
Other languages
English (en)
Inventor
Hermann Bujard
Kai Schoenig
Original Assignee
Tet Systems Holding Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tet Systems Holding Gmbh & Co filed Critical Tet Systems Holding Gmbh & Co
Application granted granted Critical
Publication of ATE417116T1 publication Critical patent/ATE417116T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/072Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
AT03790868T 2002-08-28 2003-08-06 Chromosomstellen zur stringenten kontrolle von genaktivität durch transkriptionsteuersysteme ATE417116T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40634402P 2002-08-28 2002-08-28

Publications (1)

Publication Number Publication Date
ATE417116T1 true ATE417116T1 (de) 2008-12-15

Family

ID=31978290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03790868T ATE417116T1 (de) 2002-08-28 2003-08-06 Chromosomstellen zur stringenten kontrolle von genaktivität durch transkriptionsteuersysteme

Country Status (9)

Country Link
US (1) US7666668B2 (de)
EP (1) EP1532260B1 (de)
AT (1) ATE417116T1 (de)
AU (1) AU2003263199B2 (de)
CA (1) CA2497263A1 (de)
DE (1) DE60325222D1 (de)
DK (1) DK1532260T3 (de)
ES (1) ES2320442T3 (de)
WO (1) WO2004020645A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
WO2005056752A2 (en) 2003-10-24 2005-06-23 Gencia Corporation Methods and compositions for delivering polynucleotides
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
CA2652347A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
EP2364322A1 (de) 2008-10-28 2011-09-14 Pioneer Hi-Bred International Inc. Sulfonylharnstoffreaktive repressorproteine
US9217289B2 (en) 2012-09-24 2015-12-22 Schlumberger Technology Corporation Casing drilling bottom hole assembly having wireless power and data connection
US9206644B2 (en) 2012-09-24 2015-12-08 Schlumberger Technology Corporation Positive displacement motor (PDM) rotary steerable system (RSS) and apparatus
US9217323B2 (en) 2012-09-24 2015-12-22 Schlumberger Technology Corporation Mechanical caliper system for a logging while drilling (LWD) borehole caliper
US9217299B2 (en) 2012-09-24 2015-12-22 Schlumberger Technology Corporation Drilling bottom hole assembly having wireless power and data connection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912411A (en) * 1993-06-14 1999-06-15 University Of Heidelberg Mice transgenic for a tetracycline-inducible transcriptional activator
US5866755A (en) * 1993-06-14 1999-02-02 Basf Aktiengellschaft Animals transgenic for a tetracycline-regulated transcriptional inhibitor

Also Published As

Publication number Publication date
CA2497263A1 (en) 2004-03-11
US7666668B2 (en) 2010-02-23
WO2004020645A2 (en) 2004-03-11
ES2320442T3 (es) 2009-05-22
US20080141386A1 (en) 2008-06-12
EP1532260A2 (de) 2005-05-25
AU2003263199A1 (en) 2004-03-19
WO2004020645A3 (en) 2004-04-22
DE60325222D1 (de) 2009-01-22
DK1532260T3 (da) 2009-03-09
AU2003263199B2 (en) 2008-05-01
EP1532260B1 (de) 2008-12-10

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