ATE417577T1 - Vorrichtungen für die spinalfusion - Google Patents

Vorrichtungen für die spinalfusion

Info

Publication number
ATE417577T1
ATE417577T1 AT01988544T AT01988544T ATE417577T1 AT E417577 T1 ATE417577 T1 AT E417577T1 AT 01988544 T AT01988544 T AT 01988544T AT 01988544 T AT01988544 T AT 01988544T AT E417577 T1 ATE417577 T1 AT E417577T1
Authority
AT
Austria
Prior art keywords
osteoinductive
disc space
carrier
adjacent vertebrae
implant
Prior art date
Application number
AT01988544T
Other languages
English (en)
Inventor
William Mckay
Original Assignee
Warsaw Orthopedic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warsaw Orthopedic Inc filed Critical Warsaw Orthopedic Inc
Application granted granted Critical
Publication of ATE417577T1 publication Critical patent/ATE417577T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B2017/564Methods for bone or joint treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30092Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2002/4635Special tools for implanting artificial joints using minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00353Bone cement, e.g. polymethylmethacrylate or PMMA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/38Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT01988544T 2000-10-24 2001-10-24 Vorrichtungen für die spinalfusion ATE417577T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24279400P 2000-10-24 2000-10-24

Publications (1)

Publication Number Publication Date
ATE417577T1 true ATE417577T1 (de) 2009-01-15

Family

ID=22916210

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01988544T ATE417577T1 (de) 2000-10-24 2001-10-24 Vorrichtungen für die spinalfusion

Country Status (9)

Country Link
US (3) US8226729B2 (de)
EP (2) EP1335686B1 (de)
JP (2) JP5236855B2 (de)
AT (1) ATE417577T1 (de)
AU (3) AU2586202A (de)
CA (1) CA2426406A1 (de)
DE (1) DE60137073D1 (de)
ES (2) ES2384405T3 (de)
WO (1) WO2002034116A2 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225021A1 (en) * 2001-11-14 2003-12-04 Mckay William F. Methods of inducing the expression of bone morphogenetic proteins (BMPs) and transforming growth factor-beta proteins (TGF-betas) in cells
NO316115B1 (no) * 1997-12-10 2003-12-15 Akva As Fremgangsmåte og anordning for dosert utmating av et kornet, pelletert eller granulert massegods ut av en beholder
US7435260B2 (en) * 1999-08-13 2008-10-14 Ferree Bret A Use of morphogenetic proteins to treat human disc disease
US7504374B2 (en) * 2000-10-24 2009-03-17 Warsaw Orthopedic, Inc. Method for inducing deposition and maturation of bone comprising a co-therapeutic regimen of LMP-1 and BMP-2
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
EP1610740A4 (de) * 2003-04-04 2009-04-08 Theken Disc Llc Künstliche bandscheibenprothese
CA2545185A1 (en) * 2003-11-07 2005-05-26 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
AU2004317501B2 (en) * 2004-04-13 2011-09-01 Emory University Intracellular delivery of osteoinductive proteins and peptides
US7749268B2 (en) * 2004-05-26 2010-07-06 Warsaw Orthopedic, Inc. Methods for treating the spine
US9078884B2 (en) * 2004-09-21 2015-07-14 Thomas Joseph Lally Bio-material composition and method for spinal fusion
CA2602479A1 (en) * 2005-03-22 2006-09-28 Warsaw Orthopedic, Inc. Mechanisms of osteoinduction by lim mineralization protein-1 (lmp-1)
US8092548B2 (en) * 2005-06-22 2012-01-10 Warsaw Orthopedic, Inc. Osteograft treatment to promote osteoinduction and osteograft incorporation
US20100070043A1 (en) * 2005-08-04 2010-03-18 Kitchen Michael S Shape memory orthopedic joint
US20090112321A1 (en) * 2005-08-04 2009-04-30 Kitchen Michael S Spinal stabilization device and method
US20070077267A1 (en) * 2005-10-03 2007-04-05 Sdgi Holdings, Inc. Bioactive composite implants
WO2007058878A2 (en) * 2005-11-10 2007-05-24 Warsaw Orthopedic, Inc. Mechanisms of osteoinduction by lim mineralization protein-1 (lmp-1)
US7618454B2 (en) * 2005-12-07 2009-11-17 Zimmer Spine, Inc. Transforaminal lumbar interbody fusion spacers
US9439948B2 (en) 2006-10-30 2016-09-13 The Regents Of The University Of Michigan Degradable cage coated with mineral layers for spinal interbody fusion
US8275594B2 (en) * 2006-10-30 2012-09-25 The Regents Of The University Of Michigan Engineered scaffolds for intervertebral disc repair and regeneration and for articulating joint repair and regeneration
US12171904B2 (en) 2006-10-30 2024-12-24 Trs Holdings Llc Mineral coated scaffolds
US20080102097A1 (en) * 2006-10-31 2008-05-01 Zanella John M Device and method for treating osteolysis using a drug depot to deliver an anti-inflammatory agent
US8388626B2 (en) * 2006-11-08 2013-03-05 Warsaw Orthopedic, Inc. Methods of employing calcium phosphate cement compositions and osteoinductive proteins to effect vertebrae interbody fusion absent an interbody device
EP2457539B1 (de) * 2007-04-17 2019-12-25 The Board of Trustees of the Leland Stanford Junior University Hydrogelarthroplastikvorrichtung
WO2009051779A1 (en) * 2007-10-17 2009-04-23 Kitchen Michael S Spinal stabilization device and method
US20090110637A1 (en) * 2007-10-26 2009-04-30 Warsaw Orthopedic, Inc. LMP and Regulation of Tissue Growth
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
EP2323670A4 (de) 2008-08-05 2013-12-25 Biomimedica Inc Polyurethan-gepfropfte hydrogele
US10610364B2 (en) 2008-12-04 2020-04-07 Subchondral Solutions, Inc. Method for ameliorating joint conditions and diseases and preventing bone hypertrophy
EP2523672B1 (de) 2010-01-15 2016-07-13 Rutgers, the State University of New Jersey Verwendung von vanadiumverbindungen für beschleunigte knochenheilung
US8956414B2 (en) 2010-04-21 2015-02-17 Spinecraft, LLC Intervertebral body implant, instrument and method
WO2012023113A2 (en) 2010-08-20 2012-02-23 Wyeth Llc Designer osteogenic proteins
US20170035803A1 (en) * 2010-12-10 2017-02-09 Rutgers, The State University Of New Jersey Insulin-mimetic local therapeutic adjuncts for enhancing spinal fusion
US20140322292A1 (en) 2010-12-10 2014-10-30 Rutgers, The State University Of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
AU2011343995A1 (en) * 2010-12-13 2013-06-20 Biomimetic Therapeutics, Llc Compositions and methods for spine fusion procedures
US9931348B2 (en) 2011-07-06 2018-04-03 Rutgers, The State University Of New Jersey Vanadium compounds as therapeutic adjuncts for cartilage injury and repair
AU2013334111A1 (en) * 2012-10-25 2015-05-28 Rutgers, The State University Of New Jersey Insulin-mimetic local therapeutic adjuncts for enhancing spinal fusion
US9764122B2 (en) 2014-07-25 2017-09-19 Warsaw Orthopedic, Inc. Drug delivery device and methods having an occluding member
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
AU2015374114B2 (en) 2014-12-29 2018-07-26 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
CN108495595B (zh) * 2015-11-25 2022-02-01 软骨解决方案股份有限公司 用于修复解剖关节病症的方法、系统和设备
USD802755S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
US11801143B2 (en) 2021-07-01 2023-10-31 Hyalex Orthopaedics, Inc. Multi-layered biomimetic osteochondral implants and methods of using thereof
US12343444B2 (en) 2021-08-16 2025-07-01 Bone Solutions, Inc. Structural implant to prevent bone defects

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3787900A (en) * 1971-06-09 1974-01-29 Univ Iowa State Res Found Artificial bone or tooth prosthesis material
US4394370A (en) 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4673355A (en) * 1982-10-25 1987-06-16 Farris Edward T Solid calcium phosphate materials
US5286763A (en) * 1983-03-22 1994-02-15 Massachusetts Institute Of Technology Bioerodible polymers for drug delivery in bone
US5290763A (en) 1991-04-22 1994-03-01 Intermedics Orthopedics/Denver, Inc. Osteoinductive protein mixtures and purification processes
US5290764A (en) 1992-01-14 1994-03-01 The Dupont Merck Pharmaceutical Company Stabilization of active plasminogen activator inhibitor-1
WO1993015767A1 (en) * 1992-02-05 1993-08-19 Merck & Co., Inc. Implant therapy for bone growth stimulation
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
DE4216496C2 (de) * 1992-05-19 1994-09-22 Werner Prof Dr Med Sattel Verwendung eines Plombenkörpers zum Einsetzen in eine Knochenhöhle, insbesondere in den Markraum eines Röhrenknochens
JPH06296677A (ja) * 1993-04-16 1994-10-25 Yamanouchi Pharmaceut Co Ltd 骨形成用移植体
US5514180A (en) * 1994-01-14 1996-05-07 Heggeness; Michael H. Prosthetic intervertebral devices
WO1995031947A1 (en) * 1994-05-23 1995-11-30 Spine-Tech, Inc. Intervertebral fusion implant
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US5716413A (en) 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
US6143948A (en) * 1996-05-10 2000-11-07 Isotis B.V. Device for incorporation and release of biologically active agents
DE69729647T2 (de) * 1996-10-16 2005-07-07 Etex Corp., Cambridge Verfahren zur Herstellung von wenigkristallinem Calciumphosphat und Verfahren zu dessen Verwendung
CA2268156C (en) * 1996-10-16 2007-05-29 Etex Corporation Bioceramic compositions
AU732421B2 (en) * 1996-10-23 2001-04-26 Warsaw Orthopedic, Inc. Spinal spacer
AU734950B2 (en) * 1996-10-24 2001-06-28 Warsaw Orthopedic, Inc. Ceramic fusion implants and compositions containing osteoinductive factors
JPH10151188A (ja) * 1996-11-21 1998-06-09 Yamanouchi Pharmaceut Co Ltd 骨形成用移植体
US6679918B1 (en) 1997-02-13 2004-01-20 Centerpulse Biologics Inc. Implantable putty material
DE69821510T2 (de) 1997-04-24 2004-06-24 Takeda Chemical Industries, Ltd. Mit apatit beschichtete feste zusammensetzung
CA2291718A1 (en) * 1997-05-30 1998-12-03 Osteobiologics, Inc. Fiber-reinforced, porous, biodegradable implant device
JP2002502822A (ja) * 1998-02-10 2002-01-29 オレゴン ヘルス サイエンシーズ ユニバーシティー 骨芽細胞の前駆細胞による骨欠損の治療
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
DE19834504A1 (de) * 1998-07-31 2000-02-03 Merck Patent Gmbh Verfahren zum Mischen von Calcium-Phosphat-Zementen
ES2209820T3 (es) * 1999-02-04 2004-07-01 Sdgi Holdings, Inc. Composiciones esponjosas osteogenicas altamente mineralizadas, y usos de las mismas.
US6294187B1 (en) * 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same

Also Published As

Publication number Publication date
JP2004512079A (ja) 2004-04-22
EP1335686B1 (de) 2008-12-17
EP2085055A1 (de) 2009-08-05
WO2002034116A2 (en) 2002-05-02
AU2586202A (en) 2002-05-06
AU2002225862B2 (en) 2005-05-12
US20040034428A1 (en) 2004-02-19
EP1335686A2 (de) 2003-08-20
US20090298777A1 (en) 2009-12-03
US20090298776A1 (en) 2009-12-03
EP1335686A4 (de) 2005-06-01
AU2005203606B2 (en) 2009-01-08
CA2426406A1 (en) 2002-05-02
ES2384405T3 (es) 2012-07-04
WO2002034116A3 (en) 2003-02-27
US8617252B2 (en) 2013-12-31
ES2319506T3 (es) 2009-05-08
JP5236855B2 (ja) 2013-07-17
DE60137073D1 (de) 2009-01-29
JP2010214123A (ja) 2010-09-30
US8226729B2 (en) 2012-07-24
EP2085055B1 (de) 2012-06-06
AU2005203606A1 (en) 2005-09-01

Similar Documents

Publication Publication Date Title
DE60137073D1 (de) Vorrichtungen für die spinalfusion
Gamradt et al. Bone graft for revision hip arthroplasty: biology and future applications.
Cameron et al. Evaluation of a biodegradable ceramic
Berven et al. Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation
WO2001068004A3 (en) Synthetic reinforced interbody fusion implants
US20100076572A1 (en) Device and method for reconstruction of osseous skeletal defects
CA2269342C (en) Spinal spacer
JP2011036690A (ja) 骨移植片複合材料およびスペーサー
US20020107571A1 (en) Spinal bone implant
Linovitz et al. Use of an advanced formulation of β-tricalcium phosphate as a bone extender in interbody lumbar fusion
DK2055267T3 (da) Strålegennemtrængeligt knogletransplantat
WO2001082993A3 (en) Implants for orthopedic applications
de Roeck et al. Impaction bone grafting using freeze-dried allograft in revision hip arthroplasty
ATE296643T1 (de) Osteogene pastenzusammensetzungen und ihre verwendung
ATE357264T1 (de) Keramische implantate und zusammensetzungen mit osteoinduktiven wirkstoffen
DE69609197D1 (de) Zwischenwirbelkörper
EP0361896A3 (de) Verfahren zur Verbesserung der Befestigung von Implantaten
DK1400252T3 (da) Fremgangsmåde og sammensætninger til heling og reparation af ledbrusk
JP2003505205A (ja) 核酸送達ビヒクルとしての軟骨マトリクス又は骨マトリクス
WO2006045330A1 (en) Implant for repairing a cartilage defect
McDonald et al. The enhancement of fixation of a porous-coated femoral component by autograft and allograft in the dog.
Eschenroeder et al. Enhanced stabilization of porous-coated metal implants with tricalcium phosphate granules
Older Bone implant grafting
Garino The use of impaction grafting in revision total knee arthroplasty
Griffon Evaluation of osteoproductive biomaterials: allograft, bone inducing agent, bioactive glass, and ceramics

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties