ATE417599T1 - Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate - Google Patents

Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Info

Publication number
ATE417599T1
ATE417599T1 AT04743222T AT04743222T ATE417599T1 AT E417599 T1 ATE417599 T1 AT E417599T1 AT 04743222 T AT04743222 T AT 04743222T AT 04743222 T AT04743222 T AT 04743222T AT E417599 T1 ATE417599 T1 AT E417599T1
Authority
AT
Austria
Prior art keywords
proteins
derivatives
pharmaceutical preparation
containing chitosan
intranasal application
Prior art date
Application number
AT04743222T
Other languages
English (en)
Inventor
Ann Margaret Dyer
Peter James Watts
Yu-Hui Cheng
Alan Smith
Original Assignee
Archimedes Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimedes Dev Ltd filed Critical Archimedes Dev Ltd
Application granted granted Critical
Publication of ATE417599T1 publication Critical patent/ATE417599T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04743222T 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate ATE417599T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0315632.0A GB0315632D0 (en) 2003-07-04 2003-07-04 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE417599T1 true ATE417599T1 (de) 2009-01-15

Family

ID=27741549

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743222T ATE417599T1 (de) 2003-07-04 2004-07-02 Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate

Country Status (14)

Country Link
US (2) US7662403B2 (de)
EP (1) EP1641434B1 (de)
AT (1) ATE417599T1 (de)
AU (1) AU2004255515B2 (de)
CA (1) CA2531239C (de)
DE (1) DE602004018496D1 (de)
DK (1) DK1641434T3 (de)
ES (1) ES2319995T3 (de)
GB (1) GB0315632D0 (de)
NZ (1) NZ544718A (de)
PL (1) PL1641434T3 (de)
PT (1) PT1641434E (de)
WO (1) WO2005004838A1 (de)
ZA (1) ZA200600027B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
US20090136505A1 (en) 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
GB2438834A (en) * 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
EP2043603A4 (de) * 2006-07-11 2010-10-27 Arubor Corp Prävention und therapie von rhinosinusitis mit proinflammatorischen zytokinhemmern
US20080182819A1 (en) * 2007-01-29 2008-07-31 Act Iii Licensing, Llc Chitosan compositions and methods for using chitosan compositions in the treatment of health disorders
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
EP2364153B1 (de) * 2008-11-12 2015-05-06 Synedgen, Inc. Chitosan derivate zur optimierung des gewichtszuwachses bei tieren
EP2782590A4 (de) * 2011-11-23 2016-08-03 Durect Corp Biologisch abbaubare und mittels strahlung sterilisierte arzneimittelabgabezusammensetzungen
GB201319437D0 (en) * 2013-11-04 2013-12-18 Nanomerics Ltd Delivery of drugs
EP3079668A1 (de) 2013-12-09 2016-10-19 Durect Corporation Pharmazeutisch aktive wirkstoffkomplexe, polymerkomplexe und zusammensetzungen und verfahren damit
ES2899226T3 (es) 2015-02-01 2022-03-10 Syros Pharmaceuticals Inc Composiciones liofilizadas en superficie específica elevada que comprende el arsénico destinadas a una administración oral en pacientes
US11793758B2 (en) 2018-06-22 2023-10-24 Bioralix B.V. Formulations of biological polymers for oral administration

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
GB8904370D0 (en) 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
JPH07118170A (ja) * 1993-10-19 1995-05-09 Dot:Kk 経鼻吸収薬物用キャリヤ、生理活性ペプチド組成物およびその製造法
US20010053359A1 (en) * 1994-07-26 2001-12-20 Peter Watts Drug delivery composition for the nasal administration of antiviral agents
GB9416884D0 (en) * 1994-08-20 1994-10-12 Danbiosyst Uk Drug delivery compositions
GB9419979D0 (en) 1994-10-04 1994-11-16 Medeva Holdings Bv Vaccine compositions
SE9403905D0 (sv) * 1994-11-14 1994-11-14 Astra Ab New formulations
GB9522351D0 (en) 1995-11-01 1996-01-03 Medeva Holdings Bv Vaccine compositions
GB9525083D0 (en) 1995-12-07 1996-02-07 Danbiosyst Uk Vaccine compositions
US6881423B2 (en) 1996-02-27 2005-04-19 Teijin Limited Powdery composition for nasal administration
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
ATE216264T1 (de) 1996-07-10 2002-05-15 West Pharm Serv Drug Res Ltd Gentherapiesystem zur zielung des endotheliums
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
GB9707934D0 (en) 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
GB9713980D0 (en) 1997-07-03 1997-09-10 Danbiosyst Uk New conjugates
GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
MXPA01000032A (es) * 1998-07-08 2002-10-17 Kirin Amgen Inc Preparacion que contiene farmaco de alto peso molecular en forma de polvo para administracion mucosal.
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
GB9924797D0 (en) 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20020013331A1 (en) 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
KR20080053423A (ko) 2000-07-31 2008-06-12 니코메드 댄마크 에이에스 코 투여용 펜타닐 조성물
EP1458362A4 (de) * 2001-11-19 2006-01-18 Becton Dickinson Co Pharmazeutische zusammensetzungen in teilchenform
US7666876B2 (en) 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations

Also Published As

Publication number Publication date
EP1641434B1 (de) 2008-12-17
US20100021553A1 (en) 2010-01-28
EP1641434A1 (de) 2006-04-05
ZA200600027B (en) 2009-08-26
US7662403B2 (en) 2010-02-16
AU2004255515A1 (en) 2005-01-20
ES2319995T3 (es) 2009-05-18
CA2531239C (en) 2011-05-24
WO2005004838A1 (en) 2005-01-20
CA2531239A1 (en) 2005-01-20
US8481070B2 (en) 2013-07-09
AU2004255515B2 (en) 2009-04-30
GB0315632D0 (en) 2003-08-13
WO2005004838A8 (en) 2005-03-17
DE602004018496D1 (de) 2009-01-29
AU2004255515A2 (en) 2005-01-20
NZ544718A (en) 2009-06-26
PL1641434T3 (pl) 2009-08-31
DK1641434T3 (da) 2009-04-06
PT1641434E (pt) 2009-03-19
US20060120973A1 (en) 2006-06-08

Similar Documents

Publication Publication Date Title
WO2003099771A3 (en) Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
ATE417599T1 (de) Pharmazeutische zubereitung zur intranasalen applikation von proteinen, enthaltend chitosan oder eines seiner derivate
US20230391839A1 (en) Bioactive peptides derived from snakes
ITMI20020399A0 (it) Composizioni dietetiche e/o farmaceutiche per uso umano e/o animale abase di preparati microbici probiotici
ATE330468T1 (de) Lösung zur evaluierung und konservierung
ATE405564T1 (de) 1h-imidazoä4,5-cüchinolinderivate zur behandlung von protein kinase-abhängigen krankheiten
PT749317E (pt) Aplicacoes terapeuticas de produtos dimericos de proteinas bactericidas indutoras da permeabilidade
ATE422356T1 (de) Pharmazeutische zubereitungen
BRPI0416796A (pt) compostos orgánicos
EA200800050A1 (ru) Самобуферирующиеся композиции белков
AR021074A1 (es) COMPOSICIoN FARMACÉUTICA DE MOXIFLOXACINA, PROCEDIMIENTO PARA SU PRODUCCIoN, Y USO DE DICHA COMPOSICIoN PARA PREPARAR UN MEDICAMENTO ANTIBACTERIANO.
FR2866884B1 (fr) Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
IS2310B (is) Nefholssamsetning úr rótigótíni
GEP20063818B (en) Orodispersible pharmaceutical composition comprising agomelatine
BR0314797A (pt) Derivados da pirimidineamida e o uso dos mesmos
DE69806362D1 (de) Therapeutische pulverformulierung zur pulmonaren anwendung, welche kristallines insulin enthält
ATE464878T1 (de) Pharmazeutische zusammensetzung zur nasalen anwendung von fentanyl
EA200602092A1 (ru) Способ и композиция для лечения ринита
AU2003207417A1 (en) Use of tryptophan rich peptides
GEP20063821B (en) Orodispersible pharmaceutical composition comprising perindopril
WO2004016741A3 (en) Prenylation inhibitors containing dimethyl-cyclobutane and methods of their synthesis and use
BG103905A (en) New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine
FR2866886B1 (fr) Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique
WO2007027092A3 (en) Oral composition for moisturising skin
ITMI20030862A1 (it) Prodotto alimentare comprendente estratti o aromi naturali di piante ed amminoacidi e relativo impiego per combattere la dipendenza da fumo

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1641434

Country of ref document: EP