ATE417667T1 - Vorrichtungen zur probenverarbeitung - Google Patents

Vorrichtungen zur probenverarbeitung

Info

Publication number
ATE417667T1
ATE417667T1 AT01952286T AT01952286T ATE417667T1 AT E417667 T1 ATE417667 T1 AT E417667T1 AT 01952286 T AT01952286 T AT 01952286T AT 01952286 T AT01952286 T AT 01952286T AT E417667 T1 ATE417667 T1 AT E417667T1
Authority
AT
Austria
Prior art keywords
sample processing
devices
conduits
processing devices
carriers
Prior art date
Application number
AT01952286T
Other languages
English (en)
Inventor
William Bedingham
Joel Dufresne
Michael Harms
Christopher Kokaisel
Diane North
Barry Robole
Kenneth Wood
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26909069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE417667(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Application granted granted Critical
Publication of ATE417667T1 publication Critical patent/ATE417667T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N35/00069Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255Multi-well filtration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/142Preventing evaporation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0655Valves, specific forms thereof with moving parts pinch valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0661Valves, specific forms thereof with moving parts shape memory polymer valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F27FURNACES; KILNS; OVENS; RETORTS
    • F27BFURNACES, KILNS, OVENS OR RETORTS IN GENERAL; OPEN SINTERING OR LIKE APPARATUS
    • F27B9/00Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity
    • F27B9/14Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity characterised by the path of the charge during treatment; characterised by the means by which the charge is moved during treatment
    • F27B9/16Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity characterised by the path of the charge during treatment; characterised by the means by which the charge is moved during treatment the charge moving in a circular or arcuate path
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F27FURNACES; KILNS; OVENS; RETORTS
    • F27DDETAILS OR ACCESSORIES OF FURNACES, KILNS, OVENS OR RETORTS, IN SO FAR AS THEY ARE OF KINDS OCCURRING IN MORE THAN ONE KIND OF FURNACE
    • F27D5/00Supports, screens or the like for the charge within the furnace
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Weting (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Finish Polishing, Edge Sharpening, And Grinding By Specific Grinding Devices (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
AT01952286T 2000-06-28 2001-06-28 Vorrichtungen zur probenverarbeitung ATE417667T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21450800P 2000-06-28 2000-06-28
US09/710,184 US6627159B1 (en) 2000-06-28 2000-11-10 Centrifugal filling of sample processing devices

Publications (1)

Publication Number Publication Date
ATE417667T1 true ATE417667T1 (de) 2009-01-15

Family

ID=26909069

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01952286T ATE417667T1 (de) 2000-06-28 2001-06-28 Vorrichtungen zur probenverarbeitung

Country Status (8)

Country Link
US (8) US6627159B1 (de)
EP (4) EP1295101B1 (de)
JP (2) JP4938198B2 (de)
AT (1) ATE417667T1 (de)
AU (4) AU6874501A (de)
CA (3) CA2411518A1 (de)
DE (1) DE60137042D1 (de)
WO (2) WO2002001181A2 (de)

Families Citing this family (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244622B2 (en) * 1996-04-03 2007-07-17 Applera Corporation Device and method for multiple analyte detection
US7195670B2 (en) 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
US7052545B2 (en) * 2001-04-06 2006-05-30 California Institute Of Technology High throughput screening of crystallization of materials
US8709153B2 (en) 1999-06-28 2014-04-29 California Institute Of Technology Microfludic protein crystallography techniques
AU6079500A (en) 1999-07-08 2001-01-30 Lee Angros Antigen recovery and/or staining apparatus and method
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US7951612B2 (en) * 1999-07-08 2011-05-31 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
JP2001281233A (ja) * 2000-03-28 2001-10-10 Inst Of Physical & Chemical Res 水性分配用マイクロチップおよびそれを用いた水性分配方法
US7867763B2 (en) * 2004-01-25 2011-01-11 Fluidigm Corporation Integrated chip carriers with thermocycler interfaces and methods of using the same
AU2001273057A1 (en) * 2000-06-27 2002-01-08 Fluidigm Corporation A microfluidic design automation method and system
US6734401B2 (en) * 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6720187B2 (en) * 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
AU1189702A (en) * 2000-10-13 2002-04-22 Fluidigm Corp Microfluidic device based sample injection system for analytical devices
US8097471B2 (en) 2000-11-10 2012-01-17 3M Innovative Properties Company Sample processing devices
US6875403B2 (en) * 2001-02-09 2005-04-05 Microchem Solutions Method and apparatus for reproducible sample injection on microfabricated devices
DE10108892B4 (de) * 2001-02-23 2005-08-18 Graffinity Pharmaceuticals Ag Synthesevorrichtung und Verfahren zu deren Herstellung
US6743632B2 (en) * 2001-03-14 2004-06-01 Universities Space Research Association Directional acceleration vector-driven displacement of fluids (DAVD-DOF)
WO2002081729A2 (en) 2001-04-06 2002-10-17 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
WO2004058405A1 (en) * 2001-05-02 2004-07-15 3M Innovative Properties Company Sample processing device with resealable process chamber
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
US7128876B2 (en) * 2001-07-17 2006-10-31 Agilent Technologies, Inc. Microdevice and method for component separation in a fluid
WO2003035824A1 (en) * 2001-10-25 2003-05-01 Bar-Ilan University Interactive transparent individual cells biochip processor
US8440093B1 (en) 2001-10-26 2013-05-14 Fuidigm Corporation Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
GB0128350D0 (en) * 2001-11-27 2002-01-16 Lab901 Ltd Non-rigid apparatus for microfluidic applications
US7691333B2 (en) * 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
US7347976B2 (en) * 2001-12-20 2008-03-25 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix
US7192560B2 (en) * 2001-12-20 2007-03-20 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
US6889468B2 (en) 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
US6532997B1 (en) 2001-12-28 2003-03-18 3M Innovative Properties Company Sample processing device with integral electrophoresis channels
EP2666849A3 (de) 2002-04-01 2014-05-28 Fluidigm Corporation Mikrofluidische Partikelanalysesysteme
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
JP4743165B2 (ja) * 2002-04-25 2011-08-10 東ソー株式会社 微小流路構造体
US7083974B2 (en) 2002-07-12 2006-08-01 Applera Corporation Rotatable sample disk and method of loading a sample disk
EP1385006A3 (de) * 2002-07-24 2004-09-01 F. Hoffmann-La Roche Ag System und Patrone zur Verarbeitung einer biologischen Probe
CA2492538A1 (en) 2002-07-26 2004-02-05 Applera Corporation Valve assembly for microfluidic devices, and method for opening and closing same
JP2005533652A (ja) * 2002-07-26 2005-11-10 アプレラ コーポレイション 微小流体サイズ排除デバイス、システム、および方法
US7452509B2 (en) * 2002-07-26 2008-11-18 Applied Biosystems Inc. Microfluidic device including displaceable material trap, and system
US7201881B2 (en) * 2002-07-26 2007-04-10 Applera Corporation Actuator for deformable valves in a microfluidic device, and method
US7135147B2 (en) 2002-07-26 2006-11-14 Applera Corporation Closing blade for deformable valve in a microfluidic device and method
WO2004011365A2 (en) * 2002-07-26 2004-02-05 Applera Corporation Micro-channel design features that facilitate centripetal fluid transfer
US7198759B2 (en) * 2002-07-26 2007-04-03 Applera Corporation Microfluidic devices, methods, and systems
US7214348B2 (en) 2002-07-26 2007-05-08 Applera Corporation Microfluidic size-exclusion devices, systems, and methods
US7041258B2 (en) 2002-07-26 2006-05-09 Applera Corporation Micro-channel design features that facilitate centripetal fluid transfer
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
WO2004028955A2 (en) 2002-09-25 2004-04-08 California Institute Of Technology Microfluidic large scale integration
JP5695287B2 (ja) 2002-10-02 2015-04-01 カリフォルニア インスティテュート オブ テクノロジー 微小流体の核酸解析
EP1419818B1 (de) * 2002-11-14 2013-10-30 Boehringer Ingelheim microParts GmbH Vorrichtung zum schrittweisen Transport von Flüssigkeit unter Ausnutzung von Kapillarkräften
US7169602B2 (en) 2002-12-04 2007-01-30 Applera Corporation Sample substrate for use in biological testing and method for filling a sample substrate
US7507376B2 (en) * 2002-12-19 2009-03-24 3M Innovative Properties Company Integrated sample processing devices
US20040129676A1 (en) * 2003-01-07 2004-07-08 Tan Roy H. Apparatus for transfer of an array of liquids and methods for manufacturing same
US7332129B2 (en) * 2003-01-09 2008-02-19 3M Innovative Properties Company Sample processing device having process chambers with bypass slots
US20040157343A1 (en) * 2003-02-06 2004-08-12 Applera Corporation Devices and methods for biological sample preparation
IL154677A0 (en) * 2003-02-27 2003-09-17 Univ Bar Ilan A method and apparatus for manipulating an individual cell
US7332348B2 (en) 2003-02-28 2008-02-19 Applera Corporation Sample substrate having a divided sample chamber and method of loading thereof
US8828663B2 (en) 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
US20050145496A1 (en) 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US7476363B2 (en) * 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US7666361B2 (en) * 2003-04-03 2010-02-23 Fluidigm Corporation Microfluidic devices and methods of using same
US7981600B2 (en) * 2003-04-17 2011-07-19 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene
JP2004325185A (ja) * 2003-04-23 2004-11-18 Arkray Inc 二段式検体分析用具
JP2005037368A (ja) * 2003-05-12 2005-02-10 Yokogawa Electric Corp 化学反応用カートリッジおよびその作製方法および化学反応用カートリッジ駆動システム
US20040258563A1 (en) * 2003-06-23 2004-12-23 Applera Corporation Caps for sample wells and microcards for biological materials
EP1654347B1 (de) * 2003-06-26 2014-06-04 Seng Enterprises Limited Verbesserte Materialien zur Konstruktion von Zellchips, Zellchip-Abdeckungen, Zellchip-Hüllen, prozessierte Zellchips und Verwendungen davon
US8597597B2 (en) * 2003-06-26 2013-12-03 Seng Enterprises Ltd. Picoliter well holding device and method of making the same
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
US7888110B2 (en) * 2003-06-26 2011-02-15 Seng Enterprises Ltd. Pico liter well holding device and method of making the same
US7238269B2 (en) * 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
US7413712B2 (en) 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
WO2005024436A1 (ja) * 2003-09-02 2005-03-17 Nec Corporation カスタマイズ可能なチップおよびその製造方法
US20050047967A1 (en) * 2003-09-03 2005-03-03 Industrial Technology Research Institute Microfluidic component providing multi-directional fluid movement
US20050112634A1 (en) * 2003-09-19 2005-05-26 Woudenberg Timothy M. High density sequence detection methods and apparatus
US7407630B2 (en) 2003-09-19 2008-08-05 Applera Corporation High density plate filler
US20050069949A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfabricated Fluidic Structures
US20050069462A1 (en) * 2003-09-30 2005-03-31 International Business Machines Corporation Microfluidics Packaging
US7718133B2 (en) * 2003-10-09 2010-05-18 3M Innovative Properties Company Multilayer processing devices and methods
KR100880516B1 (ko) * 2003-10-16 2009-01-28 써드 웨이브 테크놀로지스, 아이앤씨. 체액에서 핵산의 직접 검출법
USD513075S1 (en) * 2003-10-20 2005-12-20 3M Innovative Properties Company Sample processing device
US7322254B2 (en) * 2003-12-12 2008-01-29 3M Innovative Properties Company Variable valve apparatus and methods
US7837947B2 (en) * 2003-12-12 2010-11-23 3M Innovative Properties Company Sample mixing on a microfluidic device
US20050130177A1 (en) 2003-12-12 2005-06-16 3M Innovative Properties Company Variable valve apparatus and methods
US7727710B2 (en) * 2003-12-24 2010-06-01 3M Innovative Properties Company Materials, methods, and kits for reducing nonspecific binding of molecules to a surface
US7939249B2 (en) 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step
US20050142571A1 (en) * 2003-12-24 2005-06-30 3M Innovative Properties Company Methods for nucleic acid isolation and kits using solid phase material
US20050142570A1 (en) * 2003-12-24 2005-06-30 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent
SG152261A1 (en) * 2004-01-25 2009-05-29 Fluidigm Corp Crystal forming devices and systems and methods for making and using the same
CN102778432A (zh) * 2004-05-02 2012-11-14 弗卢丁公司 热反应设备及使用其的方法
JP5502275B2 (ja) * 2004-05-02 2014-05-28 フルイディグム コーポレイション 熱反応デバイスおよびその熱反応デバイスの使用方法
EP1771786B1 (de) * 2004-06-07 2017-12-20 Iquum, Inc. Mehrfachverarbeitung von proben
US7932090B2 (en) * 2004-08-05 2011-04-26 3M Innovative Properties Company Sample processing device positioning apparatus and methods
WO2006021959A2 (en) * 2004-08-25 2006-03-02 Seng Enterprises Ltd. Method and device for isolating cells
US7832429B2 (en) 2004-10-13 2010-11-16 Rheonix, Inc. Microfluidic pump and valve structures and fabrication methods
CA2586246A1 (en) * 2004-11-03 2006-05-11 Third Wave Technologies, Inc. Single step nucleic acid detection assay employing reverse transcription, polymerase chain reaction and endonuclease cleavage
CN100563832C (zh) 2005-01-20 2009-12-02 3M创新有限公司 结构化的聚合物膜以及形成这种膜的方法
ES2352344T3 (es) 2005-01-25 2011-02-17 Seng Enterprises Limited Dispositivo de microfluido para estudio de células.
GB0501590D0 (en) * 2005-01-25 2005-03-02 Ceres Power Ltd Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode
US20060252032A1 (en) * 2005-01-28 2006-11-09 Third Wave Technologies, Inc. Detection of human herpesviruses
US7709249B2 (en) * 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7507575B2 (en) 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
WO2006116616A2 (en) * 2005-04-26 2006-11-02 Applera Corporation Systems and methods for multiple analyte detection
MX2007014655A (es) * 2005-05-24 2008-04-02 Lee H Angros Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor.
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
US7527763B2 (en) * 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
USD564667S1 (en) 2005-07-05 2008-03-18 3M Innovative Properties Company Rotatable sample processing disk
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US20080014124A1 (en) * 2005-08-04 2008-01-17 Third Wave Technologies, Inc. Sample processing devices, systems and methods
US20070053800A1 (en) * 2005-09-02 2007-03-08 Applera Corporation Fluid processing device comprising sample transfer feature
US20070141555A1 (en) * 2005-10-11 2007-06-21 Mordechai Deutsch Current damper for the study of cells
WO2007044974A2 (en) * 2005-10-12 2007-04-19 The Research Foundation Of State University Of New York Absolute pcr quantification
US7482127B2 (en) * 2005-11-03 2009-01-27 Third Wave Technologies, Inc. Nucleic acid detection assays employing blocker oligonucleotides
WO2007052245A1 (en) * 2005-11-03 2007-05-10 Seng Enterprises Ltd. Method and device for studying floating, living cells
US20080181823A1 (en) * 2005-11-08 2008-07-31 Third Wave Technologies, Inc. Plate spinner systems and devices
ES2325740T3 (es) * 2006-02-09 2009-09-15 F. Hoffmann-La Roche Ag Estructura de 3d a base de sustratos de 2d.
US7815868B1 (en) * 2006-02-28 2010-10-19 Fluidigm Corporation Microfluidic reaction apparatus for high throughput screening
US20080131875A1 (en) * 2006-06-07 2008-06-05 Third Wave Technologies, Inc. Multiplex assays
US7759062B2 (en) * 2006-06-09 2010-07-20 Third Wave Technologies, Inc. T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
AU2007264161B2 (en) * 2006-06-28 2012-05-17 Anatrace Products, Llc A device and a method for promoting crystallisation
US7629124B2 (en) * 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
US20100126606A1 (en) * 2006-07-14 2010-05-27 Gordon Robert Green Microfluidic devices
JP4292279B2 (ja) * 2006-07-18 2009-07-08 ファルマ・アクセス株式会社 結晶作製器具
WO2008045251A2 (en) 2006-10-04 2008-04-17 Third Wave Technologies, Inc. Snap-back primers and detectable hairpin structures
US7582433B2 (en) * 2006-10-12 2009-09-01 Fair Isaac Corporation Devices for generating detectable polymers
US7462456B2 (en) * 2006-10-12 2008-12-09 Fair Isaac Corporation Devices for generating detectable polymers
US7521189B2 (en) * 2006-10-12 2009-04-21 Fair Isaac Corporation Devices for generating detectable polymers
US7476505B2 (en) * 2006-10-12 2009-01-13 Fair Isaac Corporation Devices for generating detectable polymers
KR100846501B1 (ko) 2006-11-09 2008-07-17 삼성전자주식회사 밸브 유닛 및 이를 구비한 유체 처리 장치
WO2008057043A1 (en) * 2006-11-09 2008-05-15 Gyros Patent Ab Improved lid
EP2107944B1 (de) * 2006-12-22 2013-03-27 3M Innovative Properties Company Verbesserte probenverarbeitungsvorrichtungen, -systeme und -verfahren
US8128893B2 (en) 2006-12-22 2012-03-06 3M Innovative Properties Company Thermal transfer methods and structures for microfluidic systems
GB2445739A (en) * 2007-01-16 2008-07-23 Lab901 Ltd Polymeric laminates containing heat seals
JP4957260B2 (ja) 2007-01-16 2012-06-20 横河電機株式会社 化学反応用カートリッジ及びその使用方法
GB2445738A (en) * 2007-01-16 2008-07-23 Lab901 Ltd Microfluidic device
KR20100017232A (ko) * 2007-04-25 2010-02-16 쓰리엠 이노베이티브 프로퍼티즈 컴파니 생물학적 물질을 단리하기 위한 조성물, 방법, 및 장치
EP2140001A2 (de) * 2007-04-25 2010-01-06 3M Innovative Properties Company Verfahren zur amplifikation von nukleinsäuren
CN101668590A (zh) 2007-04-25 2010-03-10 3M创新有限公司 化学组分和处理装置组件
WO2008134466A1 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Chemical component and processing device assembly
KR100885267B1 (ko) * 2007-05-09 2009-02-23 삼성전기주식회사 원심력과 관성을 이용한 시료 분석 장치
JP2008284626A (ja) * 2007-05-16 2008-11-27 Miraial Kk マイクロ流路デバイス
IL184183A0 (en) * 2007-06-25 2007-10-31 Benjamin Alspector Bi directional transfer of an aliquot of fluid between compartments
EP2188387A1 (de) * 2007-08-13 2010-05-26 3M Innovative Properties Company Verfahren für den nachweis wirkstoffresistenter mikroben
WO2009025161A1 (ja) * 2007-08-17 2009-02-26 Toppan Printing Co., Ltd. 反応場独立冶具及びそれを用いた反応チップ処理装置
US20090081768A1 (en) * 2007-09-21 2009-03-26 Applera Corporation Devices and Methods for Thermally Isolating Chambers of an Assay Card
CA2700532A1 (en) 2007-09-28 2009-04-02 3M Innovative Properties Company Dual oligonucleotide method of nucleic acid detection
WO2009049268A1 (en) 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
US20100273162A1 (en) * 2007-10-17 2010-10-28 Sailaja Chandrapati Rapid detection of microorganisms
WO2009054473A1 (ja) 2007-10-26 2009-04-30 Toppan Printing Co., Ltd. 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置
TWI447393B (zh) * 2007-10-26 2014-08-01 Toppan Printing Co Ltd 反應晶片及其製造方法
US20100209927A1 (en) * 2007-11-06 2010-08-19 Menon Vinod P Processing device tablet
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
US9975118B2 (en) 2007-11-15 2018-05-22 Seng Enterprises Ltd. Device for the study of living cells
DE102007063102B4 (de) * 2007-12-28 2022-02-10 Robert Bosch Gmbh Verfahren zur Erfassung eines periodisch pulsierenden Betriebsparameters
WO2009085884A1 (en) * 2007-12-28 2009-07-09 3M Innovative Properties Company Sample processing device with optical elements
CN101952727A (zh) * 2007-12-31 2011-01-19 3M创新有限公司 微生物捕获用组合物和方法
CN102301000B (zh) 2008-03-15 2015-04-29 豪洛捷公司 核酸分子扩增反应的分析组分及方法
CA2722484A1 (en) * 2008-04-24 2009-10-29 Peter D. Ludowise Analysis of nucleic acid amplification curves using wavelet transformation
JP5109824B2 (ja) * 2008-06-16 2012-12-26 凸版印刷株式会社 反応チップ処理装置
JP5228797B2 (ja) * 2008-10-28 2013-07-03 藤倉化成株式会社 液体流路装置
US9283562B2 (en) 2008-06-26 2016-03-15 Fujikura Kasei Co., Ltd. Liquid channel device and production method therefor
CA3004416A1 (en) 2008-08-29 2010-03-04 Lee H. Angros Multiplexed microscope slide staining apparatus
US8969029B2 (en) * 2008-10-17 2015-03-03 3M Innovative Properties Company Biological sterilization indicator, system, and methods of using same
CN103341370B (zh) 2008-10-28 2015-04-29 藤仓化成株式会社 液体流道装置及其制作方法
CN102317754B (zh) * 2008-12-19 2015-09-30 3M创新有限公司 用于处理样品的系统和方法
CN102301220B (zh) 2008-12-19 2014-06-25 3M创新有限公司 用于浓缩样品的系统和方法
US10203310B2 (en) 2009-01-26 2019-02-12 Detectachem Llc Chemical detection of substances by utilizing a sample medium impregnated with solid test chemicals
CN102395884A (zh) * 2009-03-23 2012-03-28 红电医学科技股份有限公司 流体检测试片及其制造方法
WO2010113959A1 (ja) 2009-03-31 2010-10-07 凸版印刷株式会社 試料分析チップ、これを用いた試料分析装置及び試料分析方法並びに試料分析チップの製造方法
USD636892S1 (en) * 2009-05-15 2011-04-26 L3 Technology Ltd. Diagnostic instrument
EP3375890B1 (de) 2009-09-10 2020-01-22 DiaSorin S.p.A. Verfahren und vorrichtungen zur bestimmung einer übersprechkorrection bei der nukleinsäureamplifikation
USD638951S1 (en) 2009-11-13 2011-05-31 3M Innovative Properties Company Sample processing disk cover
USD667561S1 (en) 2009-11-13 2012-09-18 3M Innovative Properties Company Sample processing disk cover
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
USD638550S1 (en) 2009-11-13 2011-05-24 3M Innovative Properties Company Sample processing disk cover
US20110117607A1 (en) * 2009-11-13 2011-05-19 3M Innovative Properties Company Annular compression systems and methods for sample processing devices
JP5505041B2 (ja) * 2010-03-31 2014-05-28 凸版印刷株式会社 生化学反応用チップ及びその製造方法
EP2576066A4 (de) * 2010-05-27 2015-01-07 3M Innovative Properties Co Integrierte systeme und anordnungen zur probenverarbeitung
US20130122508A1 (en) * 2010-05-27 2013-05-16 3M Innovative Properties Company Methods and articles for sample processing
EP2431747B1 (de) 2010-09-20 2013-10-23 F. Hoffmann-La Roche AG Instrument und Verfahren zum Lagern und/oder Prozessieren von Flüssigproben
EP2436446B1 (de) 2010-10-04 2016-09-21 F. Hoffmann-La Roche AG Mehrkammerplatte und Verfahren zu ihrer Befüllung mit einer Probenflüssigkeit
FR2966368B1 (fr) * 2010-10-22 2014-02-28 Biomerieux Sa Procede pour isoler un puits a echantillon d'une carte test pour analyse et carte test obtenue
WO2012062651A1 (de) * 2010-11-10 2012-05-18 Boehringer Ingelheim Microparts Gmbh Vorrichtung zur filtration von blut
CA2827614C (en) 2011-03-08 2019-07-02 Universite Laval Fluidic centripetal device
KR101992503B1 (ko) 2011-05-18 2019-06-24 디아소린 에스.피.에이. 샘플 처리 장치에서 선택된 부피의 물질의 존재를 검출하기 위한 시스템 및 방법
KR20140022399A (ko) 2011-05-18 2014-02-24 쓰리엠 이노베이티브 프로퍼티즈 컴파니 샘플 처리 장치 상의 체적 계량을 위한 시스템 및 방법
US9067205B2 (en) 2011-05-18 2015-06-30 3M Innovative Properties Company Systems and methods for valving on a sample processing device
USD672467S1 (en) 2011-05-18 2012-12-11 3M Innovative Properties Company Rotatable sample processing disk
CN103608658B (zh) 2011-06-30 2017-06-09 3M创新有限公司 利用微结构化表面检测样品中的所关注分析物的系统和方法
US9470612B2 (en) 2011-06-30 2016-10-18 3M Innovative Properties Company Systems and methods for detecting an analyte of interest in a sample using filters and microstructured surfaces
TWI582425B (zh) 2011-11-25 2017-05-11 凸版印刷股份有限公司 樣本分析晶片、樣本分析方法及基因解析方法
BR112014020083A8 (pt) 2012-02-16 2017-07-11 3M Innovative Properties Company Dispositivos indicadores biológicos de esterilização e métodos de uso
EP2647435B1 (de) * 2012-04-05 2020-08-05 ThinXXS Microtechnology AG Anordnung aus einer flusszelle und einem temperierelement
WO2013181506A1 (en) 2012-05-31 2013-12-05 The University Of North Carolina At Chapel Hill Dissolution guided wetting of structured surfaces
CN102886280B (zh) * 2012-08-28 2014-06-11 博奥生物有限公司 一种微流控芯片及其应用
US9724689B2 (en) * 2012-11-20 2017-08-08 Detectachem Llc Colorimetric test system designed to control flow of simultaneously released chemicals to a target area
WO2014158628A1 (en) 2013-03-14 2014-10-02 Hologic, Inc. Compositions and methods for analysis of nucleic acid molecules
CN105873681B (zh) * 2013-11-18 2019-10-11 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
WO2015179098A1 (en) 2014-05-21 2015-11-26 Integenx Inc. Fluidic cartridge with valve mechanism
CN106574225B (zh) 2014-08-20 2019-12-17 3M创新有限公司 用于样品分配和分析的装置和方法
US10585518B2 (en) * 2014-10-15 2020-03-10 Microsoft Technology Licensing, Llc Display module support
CN113092563B (zh) 2014-10-22 2024-06-07 尹特根埃克斯有限公司 用于样品制备、处理和分析的系统和方法
EP3302804B1 (de) 2015-05-29 2022-07-13 Illumina, Inc. Probenträger und testsystem zur durchführung bestimmter reaktionen
US10233491B2 (en) 2015-06-19 2019-03-19 IntegenX, Inc. Valved cartridge and system
JP6806374B2 (ja) * 2015-10-23 2021-01-06 国立研究開発法人科学技術振興機構 ナノ流体デバイス及び化学分析装置
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
WO2017112564A1 (en) 2015-12-22 2017-06-29 3M Innovative Properties Company Stem-well films for sample partitioning
EP3481560A4 (de) * 2016-07-08 2020-07-22 MacDonald, Dettwiler and Associates Inc. System und verfahren zur automatisierten künstlichen sichtgesteuerten abgabe von viskosen flüssigkeiten für abdichtungs- und versiegelungsarbeiten
CN109789411A (zh) 2016-10-07 2019-05-21 勃林格殷格翰维特梅迪卡有限公司 用于测试特别是生物样品的储物筒
CN107159329A (zh) * 2017-05-22 2017-09-15 天津微纳芯科技有限公司 一种用于样品检测的芯片及其封装方法
US10046322B1 (en) * 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
CN113195008B (zh) * 2018-12-21 2023-07-21 3M创新有限公司 灭菌化学指示器
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
US20240279736A1 (en) 2020-06-18 2024-08-22 Resolve Biosciences Gmbh Multiplex method for detecting different analytes and different subgroups/variations of an analyte in a sample
WO2024231149A1 (en) * 2023-05-11 2024-11-14 Sefunda Ag Fluidic cartridge with an analyte detection member

Family Cites Families (166)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3555284A (en) 1968-12-18 1971-01-12 Norman G Anderson Multistation, single channel analytical photometer and method of use
US3798459A (en) 1972-10-06 1974-03-19 Atomic Energy Commission Compact dynamic multistation photometer utilizing disposable cuvette rotor
US3856470A (en) 1973-01-10 1974-12-24 Baxter Laboratories Inc Rotor apparatus
US3855470A (en) * 1973-01-22 1974-12-17 Aquitaine Petrole Process and apparatus for x-ray crystallography
US3795451A (en) 1973-04-24 1974-03-05 Atomic Energy Commission Rotor for fast analyzer of rotary cuvette type
US3873217A (en) 1973-07-24 1975-03-25 Atomic Energy Commission Simplified rotor for fast analyzer of rotary cuvette type
US3938958A (en) 1975-03-24 1976-02-17 Corning Glass Works Fluid dispensing device
US4358979A (en) 1980-11-24 1982-11-16 Exxon Research & Engineering Co. Apparatus for cutting plastic film
US4399103A (en) 1981-01-28 1983-08-16 Ferrara Louis T Blood dispenser device
US4390499A (en) 1981-08-13 1983-06-28 International Business Machines Corporation Chemical analysis system including a test package and rotor combination
US4673657A (en) 1983-08-26 1987-06-16 The Regents Of The University Of California Multiple assay card and system
EP0139373A1 (de) * 1983-08-26 1985-05-02 The Regents Of The University Of California System für vielfache Immunoassays
US4632908A (en) 1984-05-03 1986-12-30 Abbott Laboratories Heating system for rotating members
US4580898A (en) 1984-05-31 1986-04-08 Allied Corporation Analytical system
US4708931A (en) * 1984-06-01 1987-11-24 Regents Of University Of California Laminated rod having alternating detection and spacer layers for binding assays
US5214119A (en) 1986-06-20 1993-05-25 Minnesota Mining And Manufacturing Company Block copolymer, method of making the same, dimaine precursors of the same, method of making such diamines and end products comprising the block copolymer
US4806316A (en) * 1987-03-17 1989-02-21 Becton, Dickinson And Company Disposable device for use in chemical, immunochemical and microorganism analysis
FR2634892B1 (fr) 1988-07-28 1990-09-14 Guigan Jean Dispositif pour la realisation d'analyses biologiques par detection immuno-enzymatique d'anticorps ou d'antigenes dans un serum
FR2634894B1 (de) 1988-07-28 1990-09-14 Guigan Jean
JP2502132B2 (ja) 1988-09-30 1996-05-29 三菱重工業株式会社 形状記憶ポリウレタンエラストマ―成形体
JPH0739506B2 (ja) 1988-09-30 1995-05-01 三菱重工業株式会社 形状記憶ポリマー発泡体
JPH066342B2 (ja) 1988-10-14 1994-01-26 三菱重工業株式会社 形状記憶性フィルム及びその使用法
US5135786A (en) 1988-10-14 1992-08-04 Mitsubishi Jukogyo Kabushiki Kaisha Shape memory Transparent body and method of using the same
JPH0723572B2 (ja) 1988-10-17 1995-03-15 三菱重工業株式会社 形状記憶性ポリマーによる織布
US4851371A (en) 1988-12-05 1989-07-25 Xerox Corporation Fabricating process for large array semiconductive devices
US6645758B1 (en) * 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US5229297A (en) * 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
CA2011740A1 (en) 1989-04-07 1990-10-07 Glen Connell Microwave heatable materials
CA1329698C (en) * 1989-06-12 1994-05-24 Mark Joseph Devaney, Jr. Temperature control device
US5089233A (en) * 1989-06-12 1992-02-18 Eastman Kodak Company Processing apparatus for a chemical reaction pack
US5346672A (en) 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5258163A (en) * 1990-04-14 1993-11-02 Boehringer Mannheim Gmbh Test carrier for analysis of fluids
US5219526A (en) * 1990-04-27 1993-06-15 Pb Diagnostic Systems Inc. Assay cartridge
KR0182619B1 (ko) * 1990-06-15 1999-05-01 로버트 피. 블랙버언 내장된 분석 조립체 및 장치
US5154888A (en) * 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
US5248479A (en) * 1990-11-16 1993-09-28 Abbott Laboratories Agglutination reaction device having geometrically modified chambers
US5516581A (en) 1990-12-20 1996-05-14 Minnesota Mining And Manufacturing Company Removable adhesive tape
AU656556B2 (en) 1991-03-13 1995-02-09 Minnesota Mining And Manufacturing Company Radio frequency induction heatable compositions
US5256376A (en) 1991-09-12 1993-10-26 Medical Laboratory Automation, Inc. Agglutination detection apparatus
US5278377A (en) 1991-11-27 1994-01-11 Minnesota Mining And Manufacturing Company Electromagnetic radiation susceptor material employing ferromagnetic amorphous alloy particles
US5254479A (en) * 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5744366A (en) 1992-05-01 1998-04-28 Trustees Of The University Of Pennsylvania Mesoscale devices and methods for analysis of motile cells
US5290518A (en) 1992-08-17 1994-03-01 Eastman Kodak Company Flexible extraction device with burstable sidewall
US5453246A (en) 1992-09-18 1995-09-26 Mitsubishi Yuka Bio-Clinical Laboratories, Inc. Dispensing apparatus
US5422271A (en) * 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5288463A (en) * 1992-10-23 1994-02-22 Eastman Kodak Company Positive flow control in an unvented container
EP0672110B1 (de) 1992-11-06 2000-09-13 Biolog, Inc. Testvorrichtung für flüssig- und suspensionsproben
US5425917A (en) 1992-11-09 1995-06-20 Schmid; Peter Apparatus for attaching a labeled probe and/or antibody to macromolecules
WO1994026414A1 (en) 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
SE501380C2 (sv) 1993-06-15 1995-01-30 Pharmacia Lkb Biotech Sätt att tillverka mikrokanal/mikrokavitetsstrukturer
JPH0715998A (ja) * 1993-06-21 1995-01-17 Alex Denshi Kogyo Kk 誘導電動機用制御装置
JPH0727686A (ja) 1993-07-14 1995-01-31 Shimahisa Yakuhin Kk 破砕分散用器具
DE4444269A1 (de) * 1993-12-20 1995-06-22 Ryobi Co Feuchtevolumen-Steuerungsvorrichtung für eine Offsetpresse
ES2120174T3 (es) 1994-01-11 1998-10-16 Abbott Lab Aparato y procedimiento de ciclado termico de dosificados de acidos nucleicos.
US5639428A (en) 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
KR100314996B1 (ko) 1994-11-10 2002-01-15 윌리암 제이. 버크 액체분배시스템
JPH11502973A (ja) 1995-03-29 1999-03-09 ミネソタ マイニング アンド マニュファクチャリング カンパニー 電磁力吸収複合材
WO1996034028A1 (en) 1995-04-25 1996-10-31 Minnesota Mining And Manufacturing Company Tackified polydiorganosiloxane oligourea segmented copolymers and a process for making same
AU5630296A (en) 1995-04-25 1996-11-18 Minnesota Mining And Manufacturing Company Polydiorganosiloxane polyurea segmented copolymers and a pro cess for making same
WO1996035458A2 (en) 1995-04-25 1996-11-14 Minnesota Mining And Manufacturing Company Tackified polydiorganosiloxane polyurea segmented copolymers and a process for making same
WO1996041864A1 (en) 1995-06-13 1996-12-27 The Regents Of The University Of California Diode laser heated micro-reaction chamber with sample detection means
US5849208A (en) * 1995-09-07 1998-12-15 Microfab Technoologies, Inc. Making apparatus for conducting biochemical analyses
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US20010055812A1 (en) 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
CA2239613A1 (en) 1995-12-05 1997-06-12 Alec Mian Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US6004512A (en) 1995-12-08 1999-12-21 Mj Research Sample cartridge slide block
US6068751A (en) 1995-12-18 2000-05-30 Neukermans; Armand P. Microfluidic valve and integrated microfluidic system
US5833923A (en) * 1995-12-22 1998-11-10 Universal Healthwatch, Inc. Sampling-assay interface system
US5721123A (en) 1996-01-05 1998-02-24 Microfab Technology, Inc. Methods and apparatus for direct heating of biological material
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6825047B1 (en) 1996-04-03 2004-11-30 Applera Corporation Device and method for multiple analyte detection
US6399023B1 (en) * 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5863801A (en) * 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US6429025B1 (en) * 1996-06-28 2002-08-06 Caliper Technologies Corp. High-throughput screening assay systems in microscale fluidic devices
US6143248A (en) 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
US5804141A (en) * 1996-10-15 1998-09-08 Chianese; David Reagent strip slide treating apparatus
DE19749011A1 (de) 1996-11-19 1998-05-20 Lang Volker Mikroventil
EP0946749A1 (de) 1996-11-20 1999-10-06 The Regents Of The University Of Michigan Mikrofabrizierte vorrichtungen sowie verfahren zur isothermen amplifikation von nukleinsäuren
US5811296A (en) * 1996-12-20 1998-09-22 Johnson & Johnson Clinical Diagnostics, Inc. Blocked compartments in a PCR reaction vessel
BR9808653A (pt) 1997-02-28 2001-07-31 Burstein Lab Inc Laboratório em um disco
AUPO652997A0 (en) 1997-04-30 1997-05-29 Kindconi Pty Limited Temperature cycling device and method
JP3469585B2 (ja) 1997-05-23 2003-11-25 ガメラ バイオサイエンス コーポレイション ミクロ流体工学システムでの流動運動を駆動するために向心的加速を使用するための装置および方法
EP0882982A1 (de) 1997-06-04 1998-12-09 Vrije Universiteit Brussel Verfahren und Vorrichtung zur Trennung eines Fluids
US6300138B1 (en) 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
US6375871B1 (en) 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US6426230B1 (en) 1997-08-01 2002-07-30 Qualigen, Inc. Disposable diagnostic device and method
US5876675A (en) * 1997-08-05 1999-03-02 Caliper Technologies Corp. Microfluidic devices and systems
WO1999009394A1 (en) 1997-08-15 1999-02-25 Alexion Pharmaceuticals, Inc. Apparatus for performing assays at reaction sites
US6390791B1 (en) 1997-08-20 2002-05-21 Westonbridge International Limited Micro pump comprising an inlet control member for its self-priming
DE19745373A1 (de) 1997-10-14 1999-04-15 Bayer Ag Optisches Meßsystem zur Erfassung von Lumineszenz- oder Fluoreszenzsignalen
US6013513A (en) 1997-10-30 2000-01-11 Motorola, Inc. Molecular detection apparatus
US6007914A (en) 1997-12-01 1999-12-28 3M Innovative Properties Company Fibers of polydiorganosiloxane polyurea copolymers
US6030513A (en) * 1997-12-05 2000-02-29 Applied Materials, Inc. Full face mask for capacitance-voltage measurements
GB9804483D0 (en) 1998-03-02 1998-04-29 Central Research Lab Ltd Apparatus for and method of controlling the rate of flow of fluid along a pathway
ATE241430T1 (de) * 1998-03-11 2003-06-15 Steag Microparts Gmbh Probenträger
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
US6830729B1 (en) * 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
CA2320296A1 (en) * 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
CN1309769A (zh) * 1998-06-12 2001-08-22 旭化成株式会社 分析仪
WO1999067639A1 (en) 1998-06-25 1999-12-29 Caliper Technologies Corporation High throughput methods, systems and apparatus for performing cell based screening assays
US6375901B1 (en) 1998-06-29 2002-04-23 Agilent Technologies, Inc. Chemico-mechanical microvalve and devices comprising the same
EP1097378A2 (de) 1998-07-21 2001-05-09 Burstein Laboratories Inc. Optische platten-testvorrichtung und verfahren
EP1123499A2 (de) 1998-09-22 2001-08-16 Cellomics, Inc. Miniaturisierte zellmatrixverfahren und vorrichtung für zellbasierte reihenuntersuchungen
DE19848515A1 (de) * 1998-10-21 2000-04-27 November Ag Molekulare Medizin Vorrichtung zur Durchführung biochemischer und mikrobiologischer Reaktionen
US6159368A (en) * 1998-10-29 2000-12-12 The Perkin-Elmer Corporation Multi-well microfiltration apparatus
GB9828785D0 (en) 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
ATE556149T1 (de) 1999-02-23 2012-05-15 Caliper Life Sciences Inc Manipulation von mikropartikeln in mikrofluidischen systemen
US6937330B2 (en) 1999-04-23 2005-08-30 Ppd Biomarker Discovery Sciences, Llc Disposable optical cuvette cartridge with low fluorescence material
EP1177267A1 (de) 1999-05-05 2002-02-06 3M Innovative Properties Company Silikonklebstoffe, produkte und verfahren
AU4713400A (en) 1999-05-14 2000-12-05 Gamera Bioscience Corporation A centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids
ATE272213T1 (de) 1999-06-18 2004-08-15 Gamera Bioscience Corp Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests
ATE395136T1 (de) 1999-06-22 2008-05-15 Tecan Trading Ag Vorrichtungen zur durchfuehrung von miniaturisierten in vitro amplifizierungsassays
US6929030B2 (en) 1999-06-28 2005-08-16 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US6899137B2 (en) 1999-06-28 2005-05-31 California Institute Of Technology Microfabricated elastomeric valve and pump systems
IL147302A0 (en) 1999-06-28 2002-08-14 California Inst Of Techn Microfabricated elastomeric valve and pump systems
WO2001007892A1 (en) 1999-07-27 2001-02-01 Esperion Therapeutics, Inc. Method and device for measurement of cholesterol efflux
KR20020021810A (ko) * 1999-08-11 2002-03-22 야마모토 카즈모토 분석용 카트리지 및 송액 제어 장치
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
US6431212B1 (en) 2000-05-24 2002-08-13 Jon W. Hayenga Valve for use in microfluidic structures
US6494433B2 (en) 2000-06-06 2002-12-17 The Regents Of The University Of Michigan Thermally activated polymer device
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US20020031836A1 (en) * 2000-09-11 2002-03-14 Feldstein Mark J. Fluidics system
US6508988B1 (en) 2000-10-03 2003-01-21 California Institute Of Technology Combinatorial synthesis system
US6623860B2 (en) * 2000-10-10 2003-09-23 Aclara Biosciences, Inc. Multilevel flow structures
WO2002033268A2 (en) 2000-10-18 2002-04-25 Research Foundation Of State University Of New York Microvalve
US6951632B2 (en) 2000-11-16 2005-10-04 Fluidigm Corporation Microfluidic devices for introducing and dispensing fluids from microfluidic systems
CA2431237A1 (en) 2001-01-08 2002-07-11 President And Fellows Of Harvard College Valves and pumps for microfluidic systems and method for making microfluidic systems
US20020100714A1 (en) 2001-01-31 2002-08-01 Sau Lan Tang Staats Microfluidic devices
WO2003015923A1 (en) 2001-08-20 2003-02-27 Biomicro Systems, Inc. Fluid mixing in low aspect ratio chambers
US6750039B1 (en) 2001-03-21 2004-06-15 Boston Probes, Inc. Filtration apparatus and method for the separation of microscopic entities from a fluid
US20020159920A1 (en) 2001-04-03 2002-10-31 Weigl Bernhard H. Multiple redundant microfluidic structures cross reference to related applications
US6457236B1 (en) 2001-06-05 2002-10-01 Agilent Technologies, Inc. Apparatus and method for restricting fluid flow in a planar manifold
US7318912B2 (en) 2001-06-07 2008-01-15 Nanostream, Inc. Microfluidic systems and methods for combining discrete fluid volumes
US7022290B2 (en) 2001-06-19 2006-04-04 Rutgers, The State University System structure for in situ x-ray study of electrochemical cell component performance
US6729599B2 (en) 2001-06-26 2004-05-04 Tini Alloy Company Liquid microvalve
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
KR100421359B1 (ko) 2001-07-24 2004-03-06 엘지전자 주식회사 탄성 재질의 기판 내에서 유체를 이송하는 방법 및 이를위한 장치
US7056475B2 (en) 2002-01-30 2006-06-06 Agilent Technologies, Inc. Fluidically isolated pumping and metered fluid delivery system and methods
US7048893B2 (en) 2002-02-06 2006-05-23 Sebia Mask for depositing and distributing reagents on an analytical support
US20030148537A1 (en) 2002-02-06 2003-08-07 Franck Bellon Mask for depositing and distributing reagents on an analytical support
US7125523B2 (en) 2002-04-29 2006-10-24 Agilent Technologies, Inc. Holders for arrays
US6998271B2 (en) 2002-06-03 2006-02-14 The Hong Kong Polytechnic University Luminescent sensory material for organic-halogen compounds, and methods and apparatus utilizing such
US6886610B2 (en) 2002-06-05 2005-05-03 Techelan Liquid dispenser
CN1671444A (zh) * 2002-07-24 2005-09-21 皇家飞利浦电子股份有限公司 带有检测构件的游戏板和游戏单元
AU2003254174A1 (en) 2002-07-26 2004-02-16 Applera Corporation Size-exclusion ion-exchange particles
JP2006515232A (ja) 2002-07-26 2006-05-25 アプレラ コーポレイション 微小流体デバイスにおける変形可能な弁のための閉鎖ブレードおよび方法
US7214348B2 (en) * 2002-07-26 2007-05-08 Applera Corporation Microfluidic size-exclusion devices, systems, and methods
CA2492538A1 (en) 2002-07-26 2004-02-05 Applera Corporation Valve assembly for microfluidic devices, and method for opening and closing same
US7198759B2 (en) * 2002-07-26 2007-04-03 Applera Corporation Microfluidic devices, methods, and systems
US7201881B2 (en) * 2002-07-26 2007-04-10 Applera Corporation Actuator for deformable valves in a microfluidic device, and method
US7041258B2 (en) 2002-07-26 2006-05-09 Applera Corporation Micro-channel design features that facilitate centripetal fluid transfer
US7135147B2 (en) * 2002-07-26 2006-11-14 Applera Corporation Closing blade for deformable valve in a microfluidic device and method
WO2004011365A2 (en) 2002-07-26 2004-02-05 Applera Corporation Micro-channel design features that facilitate centripetal fluid transfer
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US20040071605A1 (en) 2002-10-10 2004-04-15 Coonan Everett W. Slide-based high-throughput microplate device
US7028168B2 (en) * 2002-12-05 2006-04-11 Hewlett-Packard Development Company, L.P. System and method for performing matrix operations
US7507376B2 (en) * 2002-12-19 2009-03-24 3M Innovative Properties Company Integrated sample processing devices
US20050232818A1 (en) * 2003-09-19 2005-10-20 Donald Sandell Single sheet seal applicator and cartridge
US7056473B2 (en) 2004-04-29 2006-06-06 Response Biomedical Corp. Method and apparatus of quantitative assays
WO2006116616A2 (en) 2005-04-26 2006-11-02 Applera Corporation Systems and methods for multiple analyte detection

Also Published As

Publication number Publication date
WO2002001180A3 (en) 2002-06-27
US8435462B2 (en) 2013-05-07
WO2002001181A3 (en) 2003-01-03
EP1295101B1 (de) 2013-12-18
JP4938198B2 (ja) 2012-05-23
EP1296765B1 (de) 2008-12-17
WO2002001181A2 (en) 2002-01-03
US20060188396A1 (en) 2006-08-24
CA2412220C (en) 2009-09-29
EP2316573A1 (de) 2011-05-04
US7855083B2 (en) 2010-12-21
CA2412220A1 (en) 2002-01-03
AU7305501A (en) 2002-01-08
JP2004502164A (ja) 2004-01-22
EP1296765A2 (de) 2003-04-02
US6814935B2 (en) 2004-11-09
US20060189000A1 (en) 2006-08-24
EP2008718A1 (de) 2008-12-31
CA2680285A1 (en) 2002-01-03
US20050031494A1 (en) 2005-02-10
EP2316573B1 (de) 2012-12-19
AU6874501A (en) 2002-01-08
EP1296765B2 (de) 2013-10-30
JP4927296B2 (ja) 2012-05-09
US20060228811A1 (en) 2006-10-12
AU2001268745B2 (en) 2006-04-27
US7595200B2 (en) 2009-09-29
US7445752B2 (en) 2008-11-04
WO2002001180A2 (en) 2002-01-03
US20020048533A1 (en) 2002-04-25
DE60137042D1 (de) 2009-01-29
EP1295101A2 (de) 2003-03-26
US20060269451A1 (en) 2006-11-30
AU2001273055B2 (en) 2006-05-11
US20020064885A1 (en) 2002-05-30
JP2004516127A (ja) 2004-06-03
CA2411518A1 (en) 2002-01-03
US7026168B2 (en) 2006-04-11
US7678334B2 (en) 2010-03-16
US6627159B1 (en) 2003-09-30
EP2008718B1 (de) 2016-07-20

Similar Documents

Publication Publication Date Title
ATE417667T1 (de) Vorrichtungen zur probenverarbeitung
AU6380001A (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
ATE544776T1 (de) Chimäre dna-bindeproteine
EP0576870A3 (de) Kulturvorrichtung für Mikroorganismen.
AU8580501A (en) Method for carrying out a saliva analysis
DE69939820D1 (de) Internalisierende erbb2 antikörper
NO972455L (no) Cytokin betegnet LERK-7
MXPA03002572A (es) Secuencias de nucleotidos que intervienen en la fertilidad de los machos y metodo de su uso.
NO20004950L (no) Bom for fluidoverföring, med koaksiale fluidkanaler
DE69735929D1 (de) Anlage zur Zellenzusammensetzung und Multiplexierung, und Anlage zur Demultiplexierung
TR199900113A3 (tr) Esnek hücreli malzeme, birlesimi ve hazirlanmasi için usul.
AU2001239279A1 (en) Device and method for performing syntheses, analyses or transport processes
DE69733313D1 (de) Mehrträgerübertragung, kompatibel zum existierenden GSM-System
WO2002037944A3 (en) Multiplexed cell analysis system
FI20012579A7 (fi) Menetelmä palvelun käyttämiseksi, järjestelmä ja päätelaite
AU2001296376A1 (en) Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips
DE69921897D1 (de) Abschaltgerät für unter Druck stehende Flüssigkeitshandhabungs-Anlage
MXPA03006984A (es) Secuencia de nucleotidos que median la fertilidad masculina y metodo de uso de la misma.
GB9911972D0 (en) Module for concentrating pathogenic protozoa and concentration method using the same
WO2000023785A3 (en) Improvements in luminescence assays
AU2001288106A1 (en) Diamond electrode for measuring glucose concentration, and measuring method and apparatus employing the same
WO1999039009A8 (en) Processes for isolating, amplifying and characterizing dna
DE59201078D1 (de) Halteeinrichtung für Rohrleitungen, insbesondere für solche in Kraftwerken.
BR9813914B1 (pt) mÉtodo e aparelho para concentraÇço e pesquisa de espÉcimes microbiolàgicos.
PT1127133E (pt) Polipeptido que proporciona permeabilidade celular

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties