ATE418620T1 - Sonde zur herstellung einer polymersonde, verfahren zur herstellung einer polymersonde sowie verwendung derselben - Google Patents
Sonde zur herstellung einer polymersonde, verfahren zur herstellung einer polymersonde sowie verwendung derselbenInfo
- Publication number
- ATE418620T1 ATE418620T1 AT01917537T AT01917537T ATE418620T1 AT E418620 T1 ATE418620 T1 AT E418620T1 AT 01917537 T AT01917537 T AT 01917537T AT 01917537 T AT01917537 T AT 01917537T AT E418620 T1 ATE418620 T1 AT E418620T1
- Authority
- AT
- Austria
- Prior art keywords
- probe
- polymer
- target gene
- producing
- complementary
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 5
- 239000000523 sample Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical group NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 abstract 2
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 229940104302 cytosine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Polymerisation Methods In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000098797 | 2000-03-31 | ||
| JP2000309959 | 2000-10-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE418620T1 true ATE418620T1 (de) | 2009-01-15 |
Family
ID=26589206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01917537T ATE418620T1 (de) | 2000-03-31 | 2001-03-28 | Sonde zur herstellung einer polymersonde, verfahren zur herstellung einer polymersonde sowie verwendung derselben |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7060814B2 (de) |
| EP (1) | EP1188841B1 (de) |
| JP (1) | JP3310662B2 (de) |
| KR (1) | KR100446358B1 (de) |
| CN (1) | CN1364199B (de) |
| AT (1) | ATE418620T1 (de) |
| AU (1) | AU747848B2 (de) |
| CA (1) | CA2387755C (de) |
| DE (1) | DE60137104D1 (de) |
| DK (1) | DK1188841T3 (de) |
| ES (1) | ES2317893T3 (de) |
| PT (1) | PT1188841E (de) |
| WO (1) | WO2001075157A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020065471A (ko) * | 2000-08-30 | 2002-08-13 | 산코 준야쿠 가부시키가이샤 | 유전자의 검출방법 |
| JPWO2003029441A1 (ja) * | 2001-09-28 | 2005-01-13 | 三光純薬株式会社 | Dnaチップのシグナル増幅方法 |
| US7393636B2 (en) | 2001-11-08 | 2008-07-01 | Sanko Junyaku Co., Ltd. | Method for forming self-assembly substance using oligonucleotide synthesized by gene amplification reaction, self-assembly substance and method for detecting gene |
| CA2515734C (en) * | 2003-02-14 | 2013-04-09 | Eisai Co., Ltd. | Signal amplification method for detecting expressed gene |
| WO2004074480A1 (ja) * | 2003-02-21 | 2004-09-02 | Eisai Co., Ltd. | 変異遺伝子検出のためのシグナル増幅方法 |
| JP2005304489A (ja) * | 2004-03-24 | 2005-11-04 | Sysmex Corp | 標的物質検出用プローブセット及び標的物質検出方法。 |
| DE602005023002D1 (de) * | 2004-04-28 | 2010-09-30 | Eisai R&D Man Co Ltd | Hybridisierungsverfahren |
| DE602005020319D1 (de) * | 2004-09-08 | 2010-05-12 | Eisai R&D Man Co Ltd | Verfahren zur bildung eines signalsondenpolymers |
| ATE526402T1 (de) | 2005-02-28 | 2011-10-15 | Eisai R&D Man Co Ltd | Hilfssonden und verfahren zur verwendung davon |
| EP1854883B1 (de) | 2005-02-28 | 2011-09-28 | Eisai R&D Management Co., Ltd. | Hilfssonden und verfahren zur verwendung davon |
| JP3941828B2 (ja) * | 2005-09-15 | 2007-07-04 | トヨタ自動車株式会社 | 内燃機関の空燃比制御装置 |
| US20090117560A1 (en) * | 2005-09-27 | 2009-05-07 | Toshihiko Fujikawa | Method of Forming Self Assembly Substance on Microsphere and Method of Detecting Target Analyte |
| US7927804B2 (en) | 2006-03-15 | 2011-04-19 | Eisai & Managment Co., Ltd. | Method of forming signal probe-polymer |
| SG185315A1 (en) | 2007-10-24 | 2012-11-29 | Eisai R&D Man Co Ltd | Nucleic acid probe, and method of forming probe -polymer |
| EP2213751A1 (de) | 2007-10-31 | 2010-08-04 | Eisai R&D Management Co., Ltd. | Polymer zur erkennung einer zielsubstanz und verfahren zur erkennung einer zielsubstanz |
| JP2012070635A (ja) * | 2009-01-29 | 2012-04-12 | Eisai R & D Management Co Ltd | 核酸の検出方法 |
| US9393309B2 (en) * | 2011-04-19 | 2016-07-19 | Kyoto University | Self-gelatinizable nucleic acid |
| CN102703584B (zh) * | 2012-04-20 | 2013-08-21 | 中国人民解放军第四军医大学 | 自组装聚合分支dna探针的制备方法 |
| JPWO2013172305A1 (ja) | 2012-05-15 | 2016-01-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Rnaの検出方法及び検出用キット |
| US20150105298A1 (en) * | 2013-10-10 | 2015-04-16 | The Research Foundation For The State University Of New York | Multi-oligomer in situ hybridization probes |
| EP3746567A4 (de) * | 2018-02-26 | 2021-11-03 | CY Molecular Diagnostics, Inc | Zusammensetzung und verfahren zur affinitätsgerichteten anreicherung von seltenen spezies |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US5288609A (en) * | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
| US4882269A (en) * | 1985-12-13 | 1989-11-21 | Princeton University | Amplified hybridization assay |
| US4851331A (en) * | 1986-05-16 | 1989-07-25 | Allied Corporation | Method and kit for polynucleotide assay including primer-dependant DNA polymerase |
| US5175270A (en) * | 1986-09-10 | 1992-12-29 | Polyprobe, Inc. | Reagents for detecting and assaying nucleic acid sequences |
| AU8103687A (en) | 1986-10-14 | 1988-05-06 | Beckman Instruments, Inc. | Improved nucleic acid hybridization technique and kit therefor |
| AU2735988A (en) * | 1987-12-21 | 1989-07-13 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| US4895325A (en) * | 1988-11-10 | 1990-01-23 | Safetran Systems Corporation | Railroad gate arm lamp circuit |
| DE69118930T2 (de) * | 1990-01-26 | 1997-01-09 | Abbott Lab | Verbessertes Verfahren zur Amplifikation von Nuklein säurezielsequenz, einsetzbar für die Polymerase und Ligasekettenreaktion |
| CA2039517C (en) * | 1990-04-03 | 2006-11-07 | David Segev | Dna probe signal amplification |
| US5232831A (en) * | 1991-06-28 | 1993-08-03 | Gen-Probe Incorporated | Nucleic acid probes to streptococcus pyogenes |
| US5216143A (en) * | 1991-06-28 | 1993-06-01 | Gen-Probe Products Company | Nucleic acid probes to mycobacterium gordonae |
| FR2710075B1 (fr) * | 1993-09-15 | 1995-10-27 | Bio Merieux | Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal. |
| US5561043A (en) * | 1994-01-31 | 1996-10-01 | Trustees Of Boston University | Self-assembling multimeric nucleic acid constructs |
| US5853993A (en) * | 1996-10-21 | 1998-12-29 | Hewlett-Packard Company | Signal enhancement method and kit |
| JP3947597B2 (ja) * | 1997-06-06 | 2007-07-25 | 栄研化学株式会社 | 核酸配列の増幅方法 |
| EP1005573B1 (de) * | 1997-07-29 | 2006-05-24 | Polyprobe, Inc. | Dendritische nukleinsäuren mit maximaler selbstzusammenlagerung |
| JP3267576B2 (ja) * | 1998-11-09 | 2002-03-18 | 三光純薬株式会社 | プローブ高分子の形成方法 |
| US6277607B1 (en) * | 1999-05-24 | 2001-08-21 | Sanjay Tyagi | High specificity primers, amplification methods and kits |
| WO2002031192A1 (en) * | 2000-10-11 | 2002-04-18 | Sanko Junyaku Co., Ltd. | Method of constructing self-assembly of probes and method of detecting the same |
-
2001
- 2001-03-28 ES ES01917537T patent/ES2317893T3/es not_active Expired - Lifetime
- 2001-03-28 PT PT01917537T patent/PT1188841E/pt unknown
- 2001-03-28 CA CA002387755A patent/CA2387755C/en not_active Expired - Fee Related
- 2001-03-28 DK DK01917537T patent/DK1188841T3/da active
- 2001-03-28 AU AU44583/01A patent/AU747848B2/en not_active Ceased
- 2001-03-28 EP EP01917537A patent/EP1188841B1/de not_active Expired - Lifetime
- 2001-03-28 CN CN018005012A patent/CN1364199B/zh not_active Expired - Fee Related
- 2001-03-28 KR KR10-2001-7011142A patent/KR100446358B1/ko not_active Expired - Fee Related
- 2001-03-28 JP JP2001553955A patent/JP3310662B2/ja not_active Expired - Lifetime
- 2001-03-28 WO PCT/JP2001/002554 patent/WO2001075157A1/ja not_active Ceased
- 2001-03-28 DE DE60137104T patent/DE60137104D1/de not_active Expired - Lifetime
- 2001-03-28 AT AT01917537T patent/ATE418620T1/de active
- 2001-05-28 US US09/979,999 patent/US7060814B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030008294A1 (en) | 2003-01-09 |
| JP3310662B2 (ja) | 2002-08-05 |
| DE60137104D1 (de) | 2009-02-05 |
| CN1364199A (zh) | 2002-08-14 |
| CN1364199B (zh) | 2012-05-09 |
| CA2387755C (en) | 2007-07-03 |
| KR20020033599A (ko) | 2002-05-07 |
| EP1188841B1 (de) | 2008-12-24 |
| DK1188841T3 (da) | 2009-04-20 |
| KR100446358B1 (ko) | 2004-09-01 |
| EP1188841A1 (de) | 2002-03-20 |
| ES2317893T3 (es) | 2009-05-01 |
| AU747848B2 (en) | 2002-05-23 |
| WO2001075157A1 (en) | 2001-10-11 |
| AU4458301A (en) | 2001-10-15 |
| PT1188841E (pt) | 2009-03-24 |
| US7060814B2 (en) | 2006-06-13 |
| EP1188841A4 (de) | 2005-01-05 |
| CA2387755A1 (en) | 2001-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60137104D1 (de) | Sonde zur herstellung einer polymersonde, verfahren zur herstellung einer polymersonde sowie verwendung derselben | |
| CY1108716T1 (el) | Μεθοδος διαγνωσεως της νοσου του alzheimer με βαση μια μορφη μεταγραφης γονιδιου. | |
| ATE423221T1 (de) | Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung | |
| ATE253647T1 (de) | Verfahren und zusammensetzung zur detektion pathogener zustände | |
| ES2165446T3 (es) | Fosfonomonoester-acidos nucleicos, procedimiento para su preparacion y su utilizacion. | |
| ATE333517T1 (de) | Verfahren und sondenset zur erkennung von krebs | |
| DE60044367D1 (de) | Nichtaggregierende, nichtausschaltende oligomere, nukleotid-analoga enthaltend; verfahren zu deren herstellung und verwendung | |
| GB2375539A (en) | Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human adult liver | |
| ATE167680T1 (de) | Pteridin-nukleotidderivate als fluoreszierende sonden | |
| ATE380883T1 (de) | Direkte multiplex charakterisierung von genomischer dna | |
| DE60126006D1 (de) | Sonde, Zelle und Verfahren zur Messung der Konzentration und der Zusammensetzung von Biomasse | |
| DE69927113D1 (de) | Methode zur Genvervielfältigung | |
| WO2002074911A3 (en) | Identification of gene expression alterations underlying the aging process in mammals | |
| ATE341647T1 (de) | Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion | |
| DE3485811D1 (de) | Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird. | |
| DE69815370D1 (de) | Fluoreszend-konjugaten von nukleosiden und von nukleotiden, ihrer verfahren zur herstellung und ihrer verwendungen | |
| ATE402410T1 (de) | Verfahren zur erfassung von komponentenkonzentrationen einer dreikomponentenmischung und prozess zur kontinuierlichen herstellung von fluorwasserstoff unter nutzung des verfahrens | |
| ATE527376T1 (de) | Pna-sonden, sondensätze, verfahren und kits im zusammenhang mit dem nachweis von candida | |
| ATE279534T1 (de) | Verfahren zur bestimmung einer nukleinsäure | |
| DE60136746D1 (de) | Oligonucleotide zur markierung von oligonukleotidsonden und proteine | |
| WO2002018642A1 (fr) | Procede de detection de gene | |
| CN101550448A (zh) | 一种含双硫代核苷寡核苷酸探针在测定dna序列的应用 | |
| ATE526402T1 (de) | Hilfssonden und verfahren zur verwendung davon | |
| DE60237204D1 (de) | Verfahren und sequenzen zur determinierten nukleinsäurehybridisierung | |
| DE60311263D1 (de) | Verfahren zur bestimmung der kopienzahl einer nukleotidsequenz |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification |
Ref document number: 1188841 Country of ref document: EP |