ATE515575T1 - Verfahren und sonden für den nachweis von krebs - Google Patents

Verfahren und sonden für den nachweis von krebs

Info

Publication number
ATE515575T1
ATE515575T1 AT02721122T AT02721122T ATE515575T1 AT E515575 T1 ATE515575 T1 AT E515575T1 AT 02721122 T AT02721122 T AT 02721122T AT 02721122 T AT02721122 T AT 02721122T AT E515575 T1 ATE515575 T1 AT E515575T1
Authority
AT
Austria
Prior art keywords
methods
cancer
probe
detecting cancer
probes
Prior art date
Application number
AT02721122T
Other languages
English (en)
Inventor
Larry Morrison
Irina Sokolova
Steven Seelig
Kevin Halling
Original Assignee
Vysis Inc
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vysis Inc, Mayo Foundation filed Critical Vysis Inc
Application granted granted Critical
Publication of ATE515575T1 publication Critical patent/ATE515575T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT02721122T 2001-02-20 2002-02-20 Verfahren und sonden für den nachweis von krebs ATE515575T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27027101P 2001-02-20 2001-02-20
PCT/US2002/005379 WO2002066685A1 (en) 2001-02-20 2002-02-20 Methods and probes for the detection of cancer

Publications (1)

Publication Number Publication Date
ATE515575T1 true ATE515575T1 (de) 2011-07-15

Family

ID=23030623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02721122T ATE515575T1 (de) 2001-02-20 2002-02-20 Verfahren und sonden für den nachweis von krebs

Country Status (7)

Country Link
US (4) US20030087248A1 (de)
EP (1) EP1362124B1 (de)
JP (1) JP4251437B2 (de)
AT (1) ATE515575T1 (de)
CA (2) CA2750033A1 (de)
ES (1) ES2372007T3 (de)
WO (1) WO2002066685A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0878552A1 (de) * 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molekularer Nachweis von chromosomalen Veränderungen
JP2002513587A (ja) * 1998-05-04 2002-05-14 ダコ エー エス 染色体異常を検出するための方法およびプローブ
WO2002012563A2 (en) * 2000-08-04 2002-02-14 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
ES2372007T3 (es) * 2001-02-20 2012-01-12 Vysis, Inc. Métodos y sondas para la detección del cáncer.
EP1456668B1 (de) 2001-12-05 2007-05-02 Sense Proteomic Limited Protein arrays für allelvarianten und deren verwendung
AU2003291281A1 (en) * 2002-11-01 2004-06-07 The Ohio State University Research Foundation Cytogenetic abnormalities that are predictive of response to therapy for chronic lymphocytic leukemia
US20040248107A1 (en) * 2003-06-09 2004-12-09 Sokolova Irina A. Detection of high grade dysplasia in cervical cells
EP1631686B1 (de) 2003-06-09 2012-05-09 Vysis, Inc. Nachweis hochgradiger dysplasie in zervixzellen
ES2537631T3 (es) * 2004-05-27 2015-06-10 The Regents Of The University Of Colorado Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer
EP2789697B1 (de) * 2005-02-18 2017-07-19 Abbott Molecular Inc. Verfahren und Sonden zur Erkennung von Speiseröhrenkrebs
US8105768B2 (en) 2005-03-09 2012-01-31 Abbott Laboratories Methods of identifying patients for treatment with HER-2/neu inhibitors based on detection of HER-2/neu and TOP2A gene copy number
JP2009507227A (ja) * 2005-09-02 2009-02-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア メラノーマを診断するための方法及びプローブ組み合わせ
US20070178503A1 (en) * 2005-12-19 2007-08-02 Feng Jiang In-situ genomic DNA chip for detection of cancer
US20070218480A1 (en) * 2006-01-25 2007-09-20 The Board Of Regents Of The University Of Texas System Detection and diagnosis of smoking related cancers
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
KR20150090278A (ko) * 2006-10-25 2015-08-05 아이코니시스 인코포레이티드 암 또는 고등급 과형성증 세포의 자동화된 스크리닝 방법
US20090208965A1 (en) * 2006-10-25 2009-08-20 Ikonisys, Inc. Automated method for detecting cancers and high grade hyperplasias
US20080113350A1 (en) * 2006-11-09 2008-05-15 Terstappen Leon W M M Blood test to monitor the genetic changes of progressive cancer using immunomagnetic enrichment and fluorescence in situ hybridization (FISH)
US7960110B2 (en) 2006-11-15 2011-06-14 The Regents Of The University Of California Detection of chromosomal region copy number changes to diagnose melanoma
US20100291569A1 (en) * 2006-11-30 2010-11-18 Abbott Laboratories Assay for prediction of response to met antagonists
CN101970451A (zh) * 2007-07-26 2011-02-09 塞雷公司 高度可见的染色体特异性探针及相关方法
WO2009047756A2 (en) * 2007-10-11 2009-04-16 Bioview Ltd. Methods and kits for diagnosing lung cancer
US20090258365A1 (en) * 2008-03-25 2009-10-15 Terstappen Leon W M M METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
EP2313528A4 (de) * 2008-07-21 2012-01-25 Neodiagnostix Inc Verfahren für die zytologische analyse von zervixzellen
US8785131B2 (en) * 2008-11-11 2014-07-22 Abbott Laboratories Prognostic test for early stage non small cell lung cancer (NSCLC)
WO2010083852A1 (en) 2009-01-26 2010-07-29 Tethis S.R.L. Functionalized microfluidic device for immunofluorescence
JP2013507989A (ja) 2009-10-26 2013-03-07 アボット・ラボラトリーズ 非小細胞肺癌の予後に関連する染色体異常の検出
KR101918004B1 (ko) * 2009-10-26 2018-11-13 애보트 모레큘러 인크. 비-소세포 폐암의 예후를 측정하기 위한 진단 방법
TW201120449A (en) * 2009-10-26 2011-06-16 Abbott Lab Diagnostic methods for determining prognosis of non-small-cell lung cancer
WO2013101613A1 (en) * 2011-12-30 2013-07-04 Abbott Molecular Inc. Materials and methods for diagnosis, prognosis, monitoring of recurrence, and assessment of therapeutic/prophylactic treatment of pancreatobiliary cancer
EP2798082B1 (de) * 2011-12-30 2017-04-12 Abbott Molecular Inc. Materialien und verfahren zur diagnose, prognose und beurteilung einer therapeutischen/prophylaktischen behandlung von prostatakrebs
WO2015125027A2 (en) * 2014-02-12 2015-08-27 Leica Biosystems Newcastle Ltd. Kit and method for detecting bladder cancer
US20160083791A1 (en) * 2014-09-18 2016-03-24 Pathadvantage Associated System and method for detecting abnormalities in cervical cells
JP7678424B2 (ja) 2018-05-10 2025-05-16 学校法人順天堂 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法
JP7381003B2 (ja) * 2019-04-26 2023-11-15 学校法人順天堂 疾患解析を支援する方法、装置、及びコンピュータプログラム、並びにコンピュータアルゴリズムを訓練する方法、装置、及びプログラム
WO2023097244A1 (en) * 2021-11-24 2023-06-01 Yale University Methods of determining chromatin alterations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981725A (en) * 1989-09-08 1999-11-09 The Johns Hopkins Univiersity Structural alterations of the EGF receptor gene in human tumors
US5491224A (en) * 1990-09-20 1996-02-13 Bittner; Michael L. Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
US5658792A (en) * 1990-11-14 1997-08-19 The United States Of America As Represented By The Department Of Health And Human Services Antiproliferative protein
US5976790A (en) * 1992-03-04 1999-11-02 The Regents Of The University Of California Comparative Genomic Hybridization (CGH)
US5670314A (en) * 1994-02-22 1997-09-23 Regents Of The University Of California Genetic alterations that correlate with lung carcinomas
US5658730A (en) * 1994-12-23 1997-08-19 Ctrc Research Foundation Methods of human prostate cancer diagnosis
US5919624A (en) * 1997-01-10 1999-07-06 The United States Of America As Represented By The Department Of Health & Human Services Methods for detecting cervical cancer
US6174681B1 (en) * 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
US6613510B2 (en) * 1999-04-28 2003-09-02 Mayo Foundation For Medical Education And Research Methods and probe sets for determining prostate cancer prognosis
US6180349B1 (en) * 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
ES2372007T3 (es) * 2001-02-20 2012-01-12 Vysis, Inc. Métodos y sondas para la detección del cáncer.

Also Published As

Publication number Publication date
US20060063194A1 (en) 2006-03-23
JP2005505241A (ja) 2005-02-24
CA2438267C (en) 2012-05-15
EP1362124B1 (de) 2011-07-06
CA2438267A1 (en) 2002-08-29
ES2372007T3 (es) 2012-01-12
US7998678B2 (en) 2011-08-16
US20030087248A1 (en) 2003-05-08
WO2002066685A1 (en) 2002-08-29
CA2750033A1 (en) 2002-08-29
EP1362124A4 (de) 2005-04-20
EP1362124A1 (de) 2003-11-19
US20090298087A1 (en) 2009-12-03
JP4251437B2 (ja) 2009-04-08
US20120141987A1 (en) 2012-06-07

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