ATE419875T1 - Behandlung von sarkom bei menschen mit adenovirus-vektor tnf-alpha - Google Patents

Behandlung von sarkom bei menschen mit adenovirus-vektor tnf-alpha

Info

Publication number
ATE419875T1
ATE419875T1 AT02776411T AT02776411T ATE419875T1 AT E419875 T1 ATE419875 T1 AT E419875T1 AT 02776411 T AT02776411 T AT 02776411T AT 02776411 T AT02776411 T AT 02776411T AT E419875 T1 ATE419875 T1 AT E419875T1
Authority
AT
Austria
Prior art keywords
human
dose
tnf
sarcoma
alpha
Prior art date
Application number
AT02776411T
Other languages
English (en)
Inventor
Henrik Rasmussen
Karen Chu
Original Assignee
Genvec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21693977&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE419875(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genvec Inc filed Critical Genvec Inc
Application granted granted Critical
Publication of ATE419875T1 publication Critical patent/ATE419875T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
AT02776411T 2001-11-02 2002-11-01 Behandlung von sarkom bei menschen mit adenovirus-vektor tnf-alpha ATE419875T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/001,017 US20030086903A1 (en) 2001-11-02 2001-11-02 Therapeutic regimen for treating cancer
US10/151,633 US7214368B2 (en) 2001-11-02 2002-05-17 Therapeutic regimen for treating cancer comprising the administration of adenoviral vectors comprising a TNF-α transgene

Publications (1)

Publication Number Publication Date
ATE419875T1 true ATE419875T1 (de) 2009-01-15

Family

ID=21693977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02776411T ATE419875T1 (de) 2001-11-02 2002-11-01 Behandlung von sarkom bei menschen mit adenovirus-vektor tnf-alpha

Country Status (7)

Country Link
US (5) US20030086903A1 (de)
EP (1) EP1455840B1 (de)
JP (1) JP2005536447A (de)
AT (1) ATE419875T1 (de)
CA (1) CA2465361A1 (de)
DE (1) DE60230807D1 (de)
WO (1) WO2003039458A2 (de)

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US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8034791B2 (en) * 2001-04-06 2011-10-11 The University Of Chicago Activation of Egr-1 promoter by DNA damaging chemotherapeutics
CA2463816C (en) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US20030086903A1 (en) * 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
US20040266713A1 (en) * 2003-04-23 2004-12-30 Shan Lu Methods and compositions for solid tumor treatment
US20050027196A1 (en) * 2003-07-30 2005-02-03 Fitzgerald Loretta A. System for processing patient radiation treatment data
EP2168603A1 (de) * 2003-11-14 2010-03-31 GenVec, Inc. Therapeutisches Programm zur Behandlung von Krebs
US7563222B2 (en) 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
US7744520B2 (en) 2004-02-12 2010-06-29 Neovista, Inc. Method and apparatus for intraocular brachytherapy
EP1781284B1 (de) * 2004-08-25 2010-10-13 The University of Chicago Verwendung der kombination aus temozolomid und tnf-alpha zur behandlung von glioblastoma
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US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
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JPWO2011074564A1 (ja) * 2009-12-15 2013-04-25 タカラバイオ株式会社 アデノウイルスベクターの製造方法
US11111284B2 (en) * 2014-08-21 2021-09-07 The General Hospital Corporation Tumor necrosis factor superfamily and TNF-like ligand muteins and methods of preparing

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Also Published As

Publication number Publication date
EP1455840A2 (de) 2004-09-15
EP1455840B1 (de) 2009-01-07
US20100305199A1 (en) 2010-12-02
US20070166284A1 (en) 2007-07-19
DE60230807D1 (de) 2009-02-26
US20030086903A1 (en) 2003-05-08
JP2005536447A (ja) 2005-12-02
EP1455840A4 (de) 2004-12-15
WO2003039458A3 (en) 2003-11-20
US20120203052A1 (en) 2012-08-09
WO2003039458A2 (en) 2003-05-15
US7214368B2 (en) 2007-05-08
US20030086904A1 (en) 2003-05-08
CA2465361A1 (en) 2003-05-15

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