ATE420199T1 - Wirtszellen, die rekombinantes humanes erythropoietin exprimieren - Google Patents

Wirtszellen, die rekombinantes humanes erythropoietin exprimieren

Info

Publication number: ATE420199T1
Authority: AT; Austria
Prior art keywords: gene; epo; human erythropoietin; host cells; cells expressing
Prior art date: 1998-11-06

Application number

AT99971863T

Other languages

English (en)

Inventor

Carlos Carcagno

Marcelo Criscuolo

Carlos Melo

Juan Vidal

Original Assignee

Sterrenbeld Biotechnologie North America Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-06

Filing date

1999-11-08

Publication date

2009-01-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25590826&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE420199(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-11-06 Priority claimed from ARP980105609 external-priority patent/AR008358A1/es

1999-02-23 Priority claimed from ARP990100679 external-priority patent/AR008363A1/es

1999-11-08 Application filed by Sterrenbeld Biotechnologie North America Inc filed Critical Sterrenbeld Biotechnologie North America Inc

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE420199T1 publication Critical patent/ATE420199T1/de

Links

101000987586 Homo sapiens Eosinophil peroxidase Proteins 0.000 title abstract 2
101000920686 Homo sapiens Erythropoietin Proteins 0.000 title abstract 2
102000044890 human EPO Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 4
102000003951 Erythropoietin Human genes 0.000 abstract 2
108090000394 Erythropoietin Proteins 0.000 abstract 2
229940105423 erythropoietin Drugs 0.000 abstract 2
OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 2
108020004705 Codon Proteins 0.000 abstract 1
101150002621 EPO gene Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
210000003527 eukaryotic cell Anatomy 0.000 abstract 1
239000013613 expression plasmid Substances 0.000 abstract 1
230000002068 genetic effect Effects 0.000 abstract 1
239000001963 growth medium Substances 0.000 abstract 1
230000008488 polyadenylation Effects 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
238000001890 transfection Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT99971863T 1998-11-06 1999-11-08 Wirtszellen, die rekombinantes humanes erythropoietin exprimieren ATE420199T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ARP980105609 AR008358A1 (es)	1998-11-06	1998-11-06	Celulas huesped que expresan eritropoyetina humana recombinante y un metodo para producir un polipeptido de epo
ARP990100679 AR008363A1 (es)	1999-02-23	1999-02-23	Linea celular productora de eritropoyetina humana recombinante y la eritropoyetina humana recombinante producida por esta celula.

Publications (1)

Publication Number	Publication Date
ATE420199T1 true ATE420199T1 (de)	2009-01-15

Family

ID=25590826

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99971863T ATE420199T1 (de)	1998-11-06	1999-11-08	Wirtszellen, die rekombinantes humanes erythropoietin exprimieren

Country Status (10)

Country	Link
EP (1)	EP1124984B1 (de)
JP (2)	JP2002529100A (de)
AT (1)	ATE420199T1 (de)
AU (1)	AU1470400A (de)
BR (1)	BR9905867A (de)
CA (1)	CA2350335C (de)
CO (1)	CO5241323A1 (de)
DE (1)	DE69940267D1 (de)
ES (1)	ES2321048T3 (de)
WO (1)	WO2000028066A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9905868A (pt)	1998-11-06	2001-01-23	Bio Sidus S A	Procedimento de cultivo massivo de células de mamìfero para a obtenção de eritropoetina humana, recombinante e a eritropoetina humana recombinante obtida com tal procedimento
BR9917606A (pt)	1998-11-06	2002-12-31	Bio Sidus S A	Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
US6777205B1 (en)	1998-11-06	2004-08-17	Sterrenbeld Biotechnologie North America, Inc.	Host cells expressing recombinant human erythropoietin
AU2006277568B2 (en) *	2005-06-20	2011-06-30	Cadila Healthcare Limited	Expression vector and methods of producing high levels of proteins
SI2592148T1 (sl)	2007-10-12	2018-12-31	F. Hoffmann-La Roche Ag	Izražanje beljakovin iz več nukleinskih kislin
RU2571930C2 (ru) *	2010-02-25	2015-12-27	Дана-Фарбер Кэнсер Инститьют, Инк.	Мутации braf, обеспечивающие резистентность к ингибиторам braf
CN103864913A (zh)	2012-12-18	2014-06-18	联亚生技开发股份有限公司	重组蛋白
CA3052357A1 (en)	2017-03-10	2018-09-13	F. Hoffmann-La Roche Ag	Method for producing multispecific antibodies

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5010002A (en) *	1983-01-19	1991-04-23	Genentech, Inc.	Human t-PA production using vectors coding DHFR protein
US4703008A (en)	1983-12-13	1987-10-27	Kiren-Amgen, Inc.	DNA sequences encoding erythropoietin
NZ210501A (en)	1983-12-13	1991-08-27	Kirin Amgen Inc	Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
IL77081A (en) *	1984-12-04	1999-10-28	Genetics Inst	Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin
JPS62501010A (ja) *	1984-12-04	1987-04-23	ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド	エリトロポエチンの生産方法
US5641663A (en) *	1985-11-06	1997-06-24	Cangene Corporation	Expression system for the secretion of bioactive human granulocyte macrophage colony stimulating factor (GM-CSF) and other heterologous proteins from steptomyces
JPS62171696A (ja) *	1986-01-23	1987-07-28	Sumitomo Chem Co Ltd	ヒトエリスロポエチンの製造方法
JPH02485A (ja) *	1987-08-03	1990-01-05	Yuu Honshiyo	新規なヒトインターロイキン４、該因子を発現させるための組換えベクター及びそのベクターにより形質転換された形質転換体
IL95064A0 (en) *	1990-07-12	1991-06-10	Yeda Res & Dev	Molecular cloning of tnf binding protein
US5997856A (en) *	1988-10-05	1999-12-07	Chiron Corporation	Method and compositions for solubilization and stabilization of polypeptides, especially proteins
AU2309692A (en) *	1991-07-03	1993-02-11	Cryolife, Inc.	Method for stabilization of biomaterials
JPH05194253A (ja) *	1992-01-16	1993-08-03	Kirin Brewery Co Ltd	水溶性ポリペプチドホルモンを含む徐放性微小粒子状製剤及びその製造法
JP3790567B2 (ja) *	1994-09-30	2006-06-28	武田薬品工業株式会社	徐放剤
IL118201A (en) *	1995-05-11	2004-12-15	Roche Diagnostics Gmbh	Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
DE19539574A1 (de) *	1995-10-25	1997-04-30	Boehringer Mannheim Gmbh	Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
JPH09238688A (ja) *	1996-03-11	1997-09-16	Takeda Chem Ind Ltd	ヒトｍｃｐ−１レセプタータンパク質の製造法および用途
US6632648B1 (en) *	1996-05-14	2003-10-14	Elan Drug Delivery Limited	Methods of terminal sterilization of fibrinogen
US5851984A (en) *	1996-08-16	1998-12-22	Genentech, Inc.	Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
EP0935663A2 (de) *	1996-10-25	1999-08-18	G.D. SEARLE & CO.	Multifunktionelle agonisten des chimären hämatopoetischen rezeptors
JPH10273447A (ja) *	1997-01-29	1998-10-13	Takeda Chem Ind Ltd	徐放性マイクロスフィア、その製造法および用途

1999
- 1999-07-07 BR BR9905867-7A patent/BR9905867A/pt not_active Application Discontinuation
- 1999-11-05 CO CO99069968A patent/CO5241323A1/es active IP Right Grant
- 1999-11-08 AT AT99971863T patent/ATE420199T1/de not_active IP Right Cessation
- 1999-11-08 DE DE69940267T patent/DE69940267D1/de not_active Expired - Lifetime
- 1999-11-08 EP EP99971863A patent/EP1124984B1/de not_active Expired - Lifetime
- 1999-11-08 JP JP2000581232A patent/JP2002529100A/ja active Pending
- 1999-11-08 ES ES99971863T patent/ES2321048T3/es not_active Expired - Lifetime
- 1999-11-08 AU AU14704/00A patent/AU1470400A/en not_active Abandoned
- 1999-11-08 CA CA2350335A patent/CA2350335C/en not_active Expired - Fee Related
- 1999-11-08 WO PCT/US1999/026238 patent/WO2000028066A1/en not_active Ceased
2010
- 2010-03-16 JP JP2010059896A patent/JP2010213699A/ja active Pending

Also Published As

Publication number	Publication date
CA2350335C (en)	2013-02-26
EP1124984B1 (de)	2009-01-07
AU1470400A (en)	2000-05-29
CA2350335A1 (en)	2000-05-18
JP2010213699A (ja)	2010-09-30
EP1124984A1 (de)	2001-08-22
WO2000028066A1 (en)	2000-05-18
JP2002529100A (ja)	2002-09-10
BR9905867A (pt)	2001-01-23
CO5241323A1 (es)	2003-01-31
DE69940267D1 (de)	2009-02-26
ES2321048T3 (es)	2009-06-01
EP1124984A4 (de)	2005-05-04

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Legal Events

Date	Code	Title	Description
2009-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties