ATE420945T1 - Chemisch definiertes medium für kultivierte säugerzellen - Google Patents
Chemisch definiertes medium für kultivierte säugerzellenInfo
- Publication number
- ATE420945T1 ATE420945T1 AT02709335T AT02709335T ATE420945T1 AT E420945 T1 ATE420945 T1 AT E420945T1 AT 02709335 T AT02709335 T AT 02709335T AT 02709335 T AT02709335 T AT 02709335T AT E420945 T1 ATE420945 T1 AT E420945T1
- Authority
- AT
- Austria
- Prior art keywords
- chemically defined
- defined medium
- mammal cells
- cultured
- cultured mammal
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26884901P | 2001-02-15 | 2001-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE420945T1 true ATE420945T1 (de) | 2009-01-15 |
Family
ID=23024766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02709335T ATE420945T1 (de) | 2001-02-15 | 2002-02-05 | Chemisch definiertes medium für kultivierte säugerzellen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6900056B2 (de) |
| EP (1) | EP1360314B1 (de) |
| JP (2) | JP2005505240A (de) |
| AT (1) | ATE420945T1 (de) |
| CA (1) | CA2438148A1 (de) |
| DE (1) | DE60230858D1 (de) |
| WO (1) | WO2002066603A2 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003052064A2 (en) * | 2001-12-14 | 2003-06-26 | Centocor Inc. | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |
| CA2417689C (en) * | 2002-03-05 | 2006-05-09 | F. Hoffmann-La Roche Ag | Improved methods for growing mammalian cells in vitro |
| MXPA06003028A (es) * | 2003-09-18 | 2006-06-23 | Raven Biotechnologies Inc | Medios de cultivo de celulas. |
| JP4657108B2 (ja) * | 2003-12-26 | 2011-03-23 | 美保 古江 | Ｅｓ細胞培養用基礎培地 |
| US20080241925A1 (en) * | 2004-09-02 | 2008-10-02 | Angela Paz Judith Cruz | Three-Dimensional Self Assembly in Suspension of Adherent Cells |
| ES2361559T3 (es) * | 2004-11-02 | 2011-06-20 | Ares Trading S.A. | Medio de cultivo de células exento de suero para mamíferos. |
| US8273553B2 (en) * | 2004-11-02 | 2012-09-25 | Ares Trading S.A. | Production of growth hormone in serum-free cell culture medium for mammalian cells |
| WO2007028106A2 (en) | 2005-08-31 | 2007-03-08 | Centocor, Inc. | Host cell lines for production of antibody constant region with enhanced effector function |
| DE102005046225B4 (de) * | 2005-09-28 | 2012-01-05 | Cellca Gmbh | Verbessertes Zellkulturmedium |
| WO2008136398A1 (ja) * | 2007-04-26 | 2008-11-13 | Chugai Seiyaku Kabushiki Kaisha | 高濃度アミノ酸含有培地を用いた細胞の培養方法 |
| CA2687082C (en) | 2007-05-11 | 2014-01-14 | Amgen Inc. | Improved feed media |
| US7723491B1 (en) | 2007-05-25 | 2010-05-25 | Clemson University | Methods of isolating specific compounds from supramammary lymph node tissue |
| KR101594046B1 (ko) * | 2008-01-09 | 2016-02-15 | 첼카 게엠베하 | 개선된 배양 배지 첨가제 및 이를 이용한 방법 |
| HRP20200768T4 (hr) | 2009-08-11 | 2025-03-28 | F. Hoffmann - La Roche Ag | Proizvodnja proteina u mediju za uzgoj stanica bez glutamina |
| US8759098B2 (en) | 2009-12-04 | 2014-06-24 | Boston Biomedical Research Institute, Inc. | Method for cloning pluripotent stem cells |
| CA2797356C (en) | 2010-04-26 | 2020-12-29 | Novartis Ag | Improved cell culture medium |
| US9062106B2 (en) | 2011-04-27 | 2015-06-23 | Abbvie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| WO2012158551A1 (en) | 2011-05-13 | 2012-11-22 | Biogen Idec Ma Inc. | Methods of preventing and removing trisulfide bonds |
| CN103717729B (zh) * | 2011-07-08 | 2017-11-21 | 动量制药公司 | 细胞培养方法 |
| WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| US20130281355A1 (en) * | 2012-04-24 | 2013-10-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US20150267237A1 (en) * | 2012-04-24 | 2015-09-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US20240052392A1 (en) * | 2012-04-24 | 2024-02-15 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| WO2013176754A1 (en) | 2012-05-24 | 2013-11-28 | Abbvie Inc. | Novel purification of antibodies using hydrophobic interaction chromatography |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| HK1211981A1 (en) | 2012-09-02 | 2016-06-03 | Abbvie Inc. | Methods to control protein heterogeneity |
| NO2760138T3 (de) * | 2012-10-01 | 2018-08-04 | ||
| US20140170748A1 (en) * | 2012-12-14 | 2014-06-19 | DePuy Synthes Products, LLC | Nutrient Enriched Media for hUTC Growth |
| HK1207960A1 (en) | 2013-03-12 | 2016-02-19 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9611455B2 (en) | 2013-03-13 | 2017-04-04 | Merck Sharp & Dohme Corp. | Adapted lepidopteran insect cells for the production of recombinant proteins |
| US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
| WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| BR112016017660B1 (pt) | 2014-02-27 | 2022-04-19 | F. Hoffmann-La Roche Ag | Método para a produção de uma glicoproteína recombinante |
| WO2015137640A1 (ko) * | 2014-03-13 | 2015-09-17 | 한양대학교 산학협력단 | 화학 조성 세포 배양 배지 첨가물 |
| KR101714860B1 (ko) | 2014-03-13 | 2017-03-09 | 한양대학교 산학협력단 | 화학 조성 세포 배양 배지 첨가물 |
| US11124760B2 (en) | 2014-03-24 | 2021-09-21 | Biogen Ma Inc. | Methods for overcoming glutamine deprivation during mammalian cell culture |
| US10227559B2 (en) * | 2014-04-10 | 2019-03-12 | Bayer Healthcare Llc | Compounded media powder formulation and method of preparation of liquid medium for cell culture |
| WO2016049363A1 (en) * | 2014-09-24 | 2016-03-31 | Los Alamos National Security, Llc | Bio-assessment device and method of making the device |
| EP3090738A1 (de) * | 2015-05-04 | 2016-11-09 | Universidade de Santiago de Compostela | Riboflavin zur behandlung ischämischer schlaganfälle und/oder anderer glutamatexzitotoxizität-assoziierter erkrankungen |
| CN108603163A (zh) * | 2015-12-03 | 2018-09-28 | 默克专利股份公司 | 用于生长或检测微生物的化学成分确定的培养基 |
| KR102211270B1 (ko) | 2016-01-14 | 2021-02-04 | 디퍼이 신테스 프로덕츠, 인코포레이티드 | Hutc의 동결보존을 위한 조성물 및 방법 |
| WO2017175086A1 (en) | 2016-04-05 | 2017-10-12 | Pfizer Inc. | Cell culture process |
| JP2020127383A (ja) * | 2019-02-08 | 2020-08-27 | 学校法人 東洋大学 | 培養方法、培養装置、廃水処理方法及び廃水処理装置 |
| CA3129732A1 (en) * | 2019-02-14 | 2020-08-20 | North Grove Investments, Inc. | Compositions for maintaining the viability of living and static biological material, methods of making and the uses thereof |
| CN110241090B (zh) * | 2019-05-07 | 2023-10-13 | 江苏南农高科技股份有限公司 | 一种全悬浮细胞培养生产猪伪狂犬病毒抗原的方法 |
| SG11202110968VA (en) | 2019-12-06 | 2021-10-28 | Regeneron Pharma | Anti-vegf protein compositions and methods for producing the same |
| JP7822149B2 (ja) | 2020-10-02 | 2026-03-02 | ファイザー・インク | Ｒｓｖ ｆタンパク質生産のための細胞培養工程 |
| WO2022254319A1 (en) | 2021-06-01 | 2022-12-08 | Pfizer Inc. | Cell culture method for producing sfgfr3 polypeptide |
| CN115386534B (zh) * | 2022-10-26 | 2023-02-21 | 天信和(苏州)生物科技有限公司 | 利用无血清培养基培养bhk21细胞的方法及其在制备疫苗中的用途 |
| WO2026006162A2 (en) | 2024-06-24 | 2026-01-02 | Genentech, Inc. | B vitamin modulation |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4205126A (en) * | 1978-01-01 | 1980-05-27 | Cartaya Oscar A | Serum-free cell culture media |
| US4767704A (en) * | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| CS262822B1 (en) * | 1986-10-03 | 1989-04-14 | Kovar Jan | Synthetic medium for the cultivation of myelomic cells |
| JPH078273A (ja) * | 1993-06-14 | 1995-01-13 | Kurabo Ind Ltd | 接着性動物細胞の無血清培養法 |
| US5650317A (en) * | 1994-09-16 | 1997-07-22 | Michigan State University | Human breast epithelial cell type with stem cell and luminal epithelial cell characteristics |
| EP0802257B1 (de) * | 1996-04-19 | 2002-08-21 | Societe Des Produits Nestle S.A. | Menschliche immortalisierte Colon-Epithelialzellen |
| AU4330597A (en) * | 1996-08-30 | 1998-03-19 | Life Technologies, Inc. | Serum-free mammalian cell culture medium, and uses thereof |
| WO1998016629A1 (en) * | 1996-10-11 | 1998-04-23 | Life Technologies, Inc. | Defined systems for epithelial cell culture and use thereof |
| AU2002316230A1 (en) | 2001-06-13 | 2002-12-23 | Genentech, Inc. | Methods of culturing animal cells and polypeptide production in animal cells |
-
2002
- 2002-02-05 EP EP02709335A patent/EP1360314B1/de not_active Expired - Lifetime
- 2002-02-05 AT AT02709335T patent/ATE420945T1/de not_active IP Right Cessation
- 2002-02-05 CA CA 2438148 patent/CA2438148A1/en not_active Abandoned
- 2002-02-05 JP JP2002566310A patent/JP2005505240A/ja active Pending
- 2002-02-05 DE DE60230858T patent/DE60230858D1/de not_active Expired - Lifetime
- 2002-02-05 WO PCT/US2002/003274 patent/WO2002066603A2/en not_active Ceased
- 2002-02-05 US US10/067,382 patent/US6900056B2/en not_active Expired - Lifetime
-
2008
- 2008-03-25 JP JP2008077561A patent/JP2008178419A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002066603A2 (en) | 2002-08-29 |
| CA2438148A1 (en) | 2002-08-29 |
| US20030096402A1 (en) | 2003-05-22 |
| JP2005505240A (ja) | 2005-02-24 |
| EP1360314A4 (de) | 2004-08-11 |
| JP2008178419A (ja) | 2008-08-07 |
| EP1360314A2 (de) | 2003-11-12 |
| US6900056B2 (en) | 2005-05-31 |
| DE60230858D1 (de) | 2009-03-05 |
| WO2002066603A3 (en) | 2002-12-19 |
| EP1360314B1 (de) | 2009-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |