ATE420945T1 - Chemisch definiertes medium für kultivierte säugerzellen - Google Patents
Chemisch definiertes medium für kultivierte säugerzellenInfo
- Publication number
- ATE420945T1 ATE420945T1 AT02709335T AT02709335T ATE420945T1 AT E420945 T1 ATE420945 T1 AT E420945T1 AT 02709335 T AT02709335 T AT 02709335T AT 02709335 T AT02709335 T AT 02709335T AT E420945 T1 ATE420945 T1 AT E420945T1
- Authority
- AT
- Austria
- Prior art keywords
- chemically defined
- defined medium
- mammal cells
- cultured
- cultured mammal
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26884901P | 2001-02-15 | 2001-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE420945T1 true ATE420945T1 (de) | 2009-01-15 |
Family
ID=23024766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02709335T ATE420945T1 (de) | 2001-02-15 | 2002-02-05 | Chemisch definiertes medium für kultivierte säugerzellen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6900056B2 (de) |
| EP (1) | EP1360314B1 (de) |
| JP (2) | JP2005505240A (de) |
| AT (1) | ATE420945T1 (de) |
| CA (1) | CA2438148A1 (de) |
| DE (1) | DE60230858D1 (de) |
| WO (1) | WO2002066603A2 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1490481A4 (de) * | 2001-12-14 | 2005-12-07 | Centocor Inc | Zur herstellung von proteinen in chemisch definierten medien geeignete klonale myelomzellinien |
| CA2417689C (en) * | 2002-03-05 | 2006-05-09 | F. Hoffmann-La Roche Ag | Improved methods for growing mammalian cells in vitro |
| WO2005028626A2 (en) * | 2003-09-18 | 2005-03-31 | Raven Biotechnologies, Inc. | Cell culture media |
| CA2552229C (en) * | 2003-12-26 | 2013-03-12 | Miho Furue | Basal medium for es cell culturing |
| WO2006024966A2 (en) * | 2004-09-02 | 2006-03-09 | Angela Cruz | Three-dimensional self assembly in suspension of adherent cells |
| US8273553B2 (en) * | 2004-11-02 | 2012-09-25 | Ares Trading S.A. | Production of growth hormone in serum-free cell culture medium for mammalian cells |
| ES2361559T3 (es) * | 2004-11-02 | 2011-06-20 | Ares Trading S.A. | Medio de cultivo de células exento de suero para mamíferos. |
| AU2006287224A1 (en) | 2005-08-31 | 2007-03-08 | Centocor, Inc. | Host cell lines for production of antibody constant region with enhanced effector function |
| DE102005046225B4 (de) * | 2005-09-28 | 2012-01-05 | Cellca Gmbh | Verbessertes Zellkulturmedium |
| WO2008136398A1 (ja) * | 2007-04-26 | 2008-11-13 | Chugai Seiyaku Kabushiki Kaisha | 高濃度アミノ酸含有培地を用いた細胞の培養方法 |
| ES2392701T3 (es) | 2007-05-11 | 2012-12-13 | Amgen Inc. | Medios de alimentación mejorados |
| US7723491B1 (en) | 2007-05-25 | 2010-05-25 | Clemson University | Methods of isolating specific compounds from supramammary lymph node tissue |
| DK2250251T3 (en) * | 2008-01-09 | 2018-01-22 | Sartorius Stedim Cellca Gmbh | Improved culture medium additive and method of using it |
| MX355650B (es) * | 2009-08-11 | 2018-04-26 | Genentech Inc | Produccion de proteinas en medios de cultivo de celulas libres de glutamina. |
| WO2011069091A1 (en) | 2009-12-04 | 2011-06-09 | Boston Biomedical Research Institute, Inc. | Method for cloning pluripotent stem cells |
| AU2011246503B2 (en) | 2010-04-26 | 2013-09-26 | Novartis Ag | Improved cell culture medium |
| WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| US9562252B2 (en) | 2011-05-13 | 2017-02-07 | Biogen Ma Inc. | Methods of preventing and removing trisulfide bonds |
| CN103717729B (zh) | 2011-07-08 | 2017-11-21 | 动量制药公司 | 细胞培养方法 |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
| US20130281355A1 (en) * | 2012-04-24 | 2013-10-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US20150267237A1 (en) * | 2012-04-24 | 2015-09-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US20240052392A1 (en) * | 2012-04-24 | 2024-02-15 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| HK1211981A1 (en) | 2012-09-02 | 2016-06-03 | Abbvie Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| NO2760138T3 (de) * | 2012-10-01 | 2018-08-04 | ||
| US20140170748A1 (en) * | 2012-12-14 | 2014-06-19 | DePuy Synthes Products, LLC | Nutrient Enriched Media for hUTC Growth |
| SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| EP2970916B1 (de) | 2013-03-13 | 2021-04-14 | Merck Sharp & Dohme Corp. | Adaptierte lepidoptera-insektenzellen zur produktion rekombinanter proteine |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
| US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| RS59881B1 (sr) | 2014-02-27 | 2020-03-31 | Hoffmann La Roche | Modulacija ćelijskog rasta i glikozilacije u rekombinantnoj proizvodnji glikoproteina |
| KR101714860B1 (ko) | 2014-03-13 | 2017-03-09 | 한양대학교 산학협력단 | 화학 조성 세포 배양 배지 첨가물 |
| WO2015137640A1 (ko) * | 2014-03-13 | 2015-09-17 | 한양대학교 산학협력단 | 화학 조성 세포 배양 배지 첨가물 |
| DK3122869T3 (da) | 2014-03-24 | 2019-09-09 | Biogen Ma Inc | Fremgangsmåder til afhjælpning af glutamindeprivation under pattedyrecellekultur |
| CA2945390A1 (en) * | 2014-04-10 | 2015-10-15 | Bayer Healthcare Llc | Compounded media powder formulation and method of preparation of liquid medium for cell culture |
| US10634665B2 (en) | 2014-09-24 | 2020-04-28 | Triad National Security, Llc | Bio-assessment device and method of making the device |
| EP3090738A1 (de) * | 2015-05-04 | 2016-11-09 | Universidade de Santiago de Compostela | Riboflavin zur behandlung ischämischer schlaganfälle und/oder anderer glutamatexzitotoxizität-assoziierter erkrankungen |
| US20180355304A1 (en) * | 2015-12-03 | 2018-12-13 | Merck Patent Gmbh | Chemically defined media for the growth or detection of microorganisms |
| KR102211270B1 (ko) | 2016-01-14 | 2021-02-04 | 디퍼이 신테스 프로덕츠, 인코포레이티드 | Hutc의 동결보존을 위한 조성물 및 방법 |
| EP3440190B1 (de) | 2016-04-05 | 2024-08-28 | Pfizer Inc. | Zellkulturverfahren |
| JP2020127383A (ja) * | 2019-02-08 | 2020-08-27 | 学校法人 東洋大学 | 培養方法、培養装置、廃水処理方法及び廃水処理装置 |
| WO2020168191A1 (en) * | 2019-02-14 | 2020-08-20 | North Grove Investments, Inc. | Compositions for maintaining the viability of living and static biological material, methods of making and the uses thereof |
| CN110241090B (zh) * | 2019-05-07 | 2023-10-13 | 江苏南农高科技股份有限公司 | 一种全悬浮细胞培养生产猪伪狂犬病毒抗原的方法 |
| IL309560B2 (en) | 2019-12-06 | 2025-05-01 | Regeneron Pharma | Anti-VEGF protein preparations and methods for their production |
| JP7822149B2 (ja) | 2020-10-02 | 2026-03-02 | ファイザー・インク | Ｒｓｖ ｆタンパク質生産のための細胞培養工程 |
| JP2022184798A (ja) | 2021-06-01 | 2022-12-13 | ファイザー・インク | ｓＦＧＦＲ３ポリペプチドを生産するための細胞培養方法 |
| CN115386534B (zh) * | 2022-10-26 | 2023-02-21 | 天信和(苏州)生物科技有限公司 | 利用无血清培养基培养bhk21细胞的方法及其在制备疫苗中的用途 |
| WO2026006162A2 (en) | 2024-06-24 | 2026-01-02 | Genentech, Inc. | B vitamin modulation |
| WO2026117553A1 (en) | 2024-11-27 | 2026-06-04 | Genentech, Inc. | Eukaryotic cell media |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4205126A (en) * | 1978-01-01 | 1980-05-27 | Cartaya Oscar A | Serum-free cell culture media |
| US4767704A (en) * | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| CS262822B1 (en) * | 1986-10-03 | 1989-04-14 | Kovar Jan | Synthetic medium for the cultivation of myelomic cells |
| JPH078273A (ja) * | 1993-06-14 | 1995-01-13 | Kurabo Ind Ltd | 接着性動物細胞の無血清培養法 |
| US5650317A (en) * | 1994-09-16 | 1997-07-22 | Michigan State University | Human breast epithelial cell type with stem cell and luminal epithelial cell characteristics |
| ATE222598T1 (de) * | 1996-04-19 | 2002-09-15 | Nestle Sa | Menschliche immortalisierte colon- epithelialzellen |
| EP2221361A3 (de) * | 1996-08-30 | 2011-02-09 | Life Technologies Corporation | Methode zur Herstellung eines Polypeptids in vitro in einer Säugerzelle in einem Kulturmedium ohne Serum und ohne Proteine |
| DE69737455T2 (de) * | 1996-10-11 | 2007-12-06 | Invitrogen Corp., Carlsbad | Definierte systeme zur kultivierung epithelialer zellen und anwendung derselben |
| US20030087372A1 (en) | 2001-06-13 | 2003-05-08 | Genentech, Inc. | Methods of culturing animal cells and polypeptide production in animal cells |
-
2002
- 2002-02-05 DE DE60230858T patent/DE60230858D1/de not_active Expired - Lifetime
- 2002-02-05 JP JP2002566310A patent/JP2005505240A/ja active Pending
- 2002-02-05 AT AT02709335T patent/ATE420945T1/de not_active IP Right Cessation
- 2002-02-05 US US10/067,382 patent/US6900056B2/en not_active Expired - Lifetime
- 2002-02-05 CA CA 2438148 patent/CA2438148A1/en not_active Abandoned
- 2002-02-05 EP EP02709335A patent/EP1360314B1/de not_active Expired - Lifetime
- 2002-02-05 WO PCT/US2002/003274 patent/WO2002066603A2/en not_active Ceased
-
2008
- 2008-03-25 JP JP2008077561A patent/JP2008178419A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20030096402A1 (en) | 2003-05-22 |
| WO2002066603A2 (en) | 2002-08-29 |
| DE60230858D1 (de) | 2009-03-05 |
| JP2008178419A (ja) | 2008-08-07 |
| JP2005505240A (ja) | 2005-02-24 |
| CA2438148A1 (en) | 2002-08-29 |
| EP1360314A2 (de) | 2003-11-12 |
| EP1360314A4 (de) | 2004-08-11 |
| US6900056B2 (en) | 2005-05-31 |
| WO2002066603A3 (en) | 2002-12-19 |
| EP1360314B1 (de) | 2009-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |