ATE430807T1 - Verfahren zur kultivierung von circovirus - Google Patents

Verfahren zur kultivierung von circovirus

Info

Publication number
ATE430807T1
ATE430807T1 AT02712700T AT02712700T ATE430807T1 AT E430807 T1 ATE430807 T1 AT E430807T1 AT 02712700 T AT02712700 T AT 02712700T AT 02712700 T AT02712700 T AT 02712700T AT E430807 T1 ATE430807 T1 AT E430807T1
Authority
AT
Austria
Prior art keywords
circovirus
cultivation
methods
culturing
present
Prior art date
Application number
AT02712700T
Other languages
English (en)
Inventor
Qiang Liu
Suresh Tikoo
Philip Willson
Lorne Babiuk
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Application granted granted Critical
Publication of ATE430807T1 publication Critical patent/ATE430807T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10051—Methods of production or purification of viral material
    • C12N2750/10052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT02712700T 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus ATE430807T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917301P 2001-03-27 2001-03-27
PCT/CA2002/000413 WO2002077210A2 (en) 2001-03-27 2002-03-27 Methods to culture circovirus

Publications (1)

Publication Number Publication Date
ATE430807T1 true ATE430807T1 (de) 2009-05-15

Family

ID=23067939

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02712700T ATE430807T1 (de) 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus

Country Status (24)

Country Link
US (3) US6794163B2 (de)
EP (1) EP1379671B1 (de)
JP (1) JP4038127B2 (de)
KR (1) KR100876629B1 (de)
CN (2) CN1309836C (de)
AT (1) ATE430807T1 (de)
AU (1) AU2002244584B2 (de)
BR (1) BRPI0208456B8 (de)
CA (1) CA2442135C (de)
CY (1) CY1109267T1 (de)
CZ (1) CZ304525B6 (de)
DE (1) DE60232234D1 (de)
DK (1) DK1379671T3 (de)
ES (1) ES2324466T3 (de)
HU (1) HU228065B1 (de)
MX (1) MXPA03008810A (de)
MY (2) MY146518A (de)
PL (1) PL202951B1 (de)
PT (1) PT1379671E (de)
RU (2) RU2312142C2 (de)
SK (1) SK287969B6 (de)
UA (1) UA82647C2 (de)
WO (1) WO2002077210A2 (de)
ZA (1) ZA200307517B (de)

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US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
CN1309836C (zh) * 2001-03-27 2007-04-11 萨斯喀彻温大学 培养环状病毒的方法
US20030096377A1 (en) * 2001-06-28 2003-05-22 Virginia Tech Intellectual Properties, Inc. Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
EP1968630B1 (de) 2005-12-29 2018-01-24 Boehringer Ingelheim Vetmedica, Inc. Multivalente immunogene pcv2-zusammensetzungen
MX338626B (es) 2005-12-29 2016-04-26 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos.
EP2859900A1 (de) * 2006-12-11 2015-04-15 Boehringer Ingelheim Vetmedica, Inc. Wirksames Verfahren zur Behandlung von Infektionen mit dem porcinen Circovirus und Lawsonia intracellularis
JP5200223B2 (ja) * 2006-12-15 2013-06-05 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド Ｐｃｖ２抗原によるブタの処置
EP1941903A1 (de) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxe und Behandlung von PRDC
EP1958644A1 (de) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Vorbeugung und Behandlung von subklinischer PCVD
CN101688185B (zh) * 2007-05-11 2013-05-22 淡马锡生命科学研究院有限公司 对2型猪环状构象病毒(pcv2)感染高度容许的均质细胞系的产生
WO2008151215A1 (en) * 2007-06-04 2008-12-11 Merial Limited Production of porcine circovirus proteins in plants
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
CA2710247C (en) * 2007-12-21 2014-02-18 Wyeth Llc Methods and compositions for immunizing pigs against porcine circovirus
WO2009088950A2 (en) * 2007-12-31 2009-07-16 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 virus like particle with foreign amino acid insertion
KR20100113582A (ko) * 2008-01-23 2010-10-21 베링거잉겔하임베트메디카인코퍼레이티드 Ｐｃｖ2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법
CN102065890B (zh) * 2008-04-16 2014-04-02 弗吉尼亚科技知识产权公司 嵌合体猪圆环病毒PCV2Gen-1Rep及其用途
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
WO2011091389A2 (en) * 2010-01-25 2011-07-28 Blood Systems, Inc. Cyclovirus and method of use
EP3049106A1 (de) 2013-09-25 2016-08-03 Zoetis Services LLC Divergente impfstoffzusammensetzung gegen pcv2b und verfahren zur verwendung
US9505808B2 (en) 2013-10-02 2016-11-29 Boehringer Ingelheim Vetmedica, Inc. PCV2 ORF2 protein variant and virus like particles composed thereof
HK1252427A1 (zh) * 2015-05-14 2019-05-24 Boehringer Ingelheim Animal Health USA Inc. 猪环状病毒生产方法和pcv2疫苗
WO2018071511A1 (en) * 2016-10-11 2018-04-19 Orion Labs Group communication forwarding to a secondary service
CN114934020B (zh) * 2022-01-30 2024-02-13 山东省滨州畜牧兽医研究院 猪视网膜上皮细胞系及其建立方法和应用

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AU729579B2 (en) * 1996-10-23 2001-02-01 Trustees Of The University Of Pennsylvania, The Immunotherapy and improved vaccines
AUPO856097A0 (en) 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
FR2781159B1 (fr) 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
US6391314B1 (en) 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US7192594B2 (en) 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
EP1064024A4 (de) 1998-03-13 2005-04-06 Univ Georgia Res Found Impfstoffe gegen circovirus infektionen
US6492343B1 (en) 1998-04-15 2002-12-10 University Of Saskatchewan Porcine adenovirus type 3 genome
CN1211387C (zh) 1998-09-08 2005-07-20 布里奇·P·吉利 化学发光的1,2－二氧丁环
US6458586B1 (en) 1998-11-02 2002-10-01 University Of Saskatchewan Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
FR2789695B1 (fr) 1999-02-11 2003-03-07 Merial Sas Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
US6497883B1 (en) 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
US6943152B1 (en) 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
CA2413265A1 (en) 2000-05-03 2001-11-08 University Of Guelph Porcine adenovirus type 5 vector and vaccine
CN1309836C (zh) 2001-03-27 2007-04-11 萨斯喀彻温大学 培养环状病毒的方法

Also Published As

Publication number Publication date
RU2003131342A (ru) 2005-04-20
RU2007110808A (ru) 2008-09-27
US6794163B2 (en) 2004-09-21
CA2442135C (en) 2008-08-19
CY1109267T1 (el) 2014-07-02
AU2002244584B2 (en) 2006-12-14
DK1379671T3 (da) 2009-06-29
UA82647C2 (uk) 2008-05-12
CZ304525B6 (cs) 2014-06-18
US20050239187A1 (en) 2005-10-27
MY148759A (en) 2013-05-31
BRPI0208456B8 (pt) 2021-05-25
US20070128700A1 (en) 2007-06-07
US7560278B2 (en) 2009-07-14
CN1625598A (zh) 2005-06-08
JP2005500822A (ja) 2005-01-13
ZA200307517B (en) 2004-09-27
PL364077A1 (en) 2004-12-13
WO2002077210A2 (en) 2002-10-03
CZ20032584A3 (en) 2004-03-17
HU228065B1 (en) 2012-09-28
US20020177216A1 (en) 2002-11-28
MXPA03008810A (es) 2004-02-17
CA2442135A1 (en) 2002-10-03
EP1379671A2 (de) 2004-01-14
HUP0500161A3 (en) 2010-01-28
MY146518A (en) 2012-08-15
SK12102003A3 (sk) 2004-05-04
PL202951B1 (pl) 2009-08-31
JP4038127B2 (ja) 2008-01-23
BR0208456A (pt) 2004-03-02
CN1309836C (zh) 2007-04-11
US7172899B2 (en) 2007-02-06
WO2002077210A3 (en) 2003-08-21
PT1379671E (pt) 2009-07-20
HUP0500161A2 (hu) 2005-05-30
RU2312142C2 (ru) 2007-12-10
KR20040002881A (ko) 2004-01-07
EP1379671B1 (de) 2009-05-06
ES2324466T3 (es) 2009-08-07
KR100876629B1 (ko) 2009-01-07
CN1840656A (zh) 2006-10-04
SK287969B6 (sk) 2012-08-06
DE60232234D1 (de) 2009-06-18
CN1840656B (zh) 2010-06-02
BRPI0208456B1 (pt) 2016-10-18

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