ATE421502T1 - Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen - Google Patents

Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Info

Publication number
ATE421502T1
ATE421502T1 AT01981242T AT01981242T ATE421502T1 AT E421502 T1 ATE421502 T1 AT E421502T1 AT 01981242 T AT01981242 T AT 01981242T AT 01981242 T AT01981242 T AT 01981242T AT E421502 T1 ATE421502 T1 AT E421502T1
Authority
AT
Austria
Prior art keywords
pain
treatment
type calcium
calcium channel
channel antagonists
Prior art date
Application number
AT01981242T
Other languages
English (en)
Inventor
Marc Chapdelaine
Lucius Kemp
John Mccauley
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE421502T1 publication Critical patent/ATE421502T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT01981242T 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen ATE421502T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0004056A SE0004056D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain

Publications (1)

Publication Number Publication Date
ATE421502T1 true ATE421502T1 (de) 2009-02-15

Family

ID=20281716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01981242T ATE421502T1 (de) 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Country Status (9)

Country Link
US (1) US6841680B2 (de)
EP (1) EP1339690B1 (de)
JP (1) JP2004513118A (de)
AT (1) ATE421502T1 (de)
AU (1) AU2002212897A1 (de)
DE (1) DE60137534D1 (de)
ES (1) ES2319259T3 (de)
SE (1) SE0004056D0 (de)
WO (1) WO2002036569A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2862301B1 (fr) * 2003-11-17 2007-12-21 Aventis Pharma Sa Nouveau procede de preparation de quinoleines 3-fluorees
EP1871372A4 (de) * 2005-04-08 2010-06-02 Neuromed Pharmaceuticals Ltd Kombinationstherapie mit einem calciumkanalblocker vom n-typ zur schmerzminderung
US8362021B2 (en) * 2006-05-11 2013-01-29 Zalicus Pharmaceuticals Ltd. Method for increasing the bioavailability of benzhydryl piperazine containing compounds
CA2815960C (en) 2010-10-29 2019-01-22 Clino Ltd. Tau imaging probe
EP2654726A1 (de) 2011-03-08 2013-10-30 Zalicus Pharmaceuticals Ltd. Festdispersionsformulierungen und verwendungsverfahren dafür
US8409560B2 (en) 2011-03-08 2013-04-02 Zalicus Pharmaceuticals Ltd. Solid dispersion formulations and methods of use thereof
DE102016125645A1 (de) * 2016-12-23 2018-06-28 Forschungszentrum Jülich GmbH D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504294A (ja) * 1991-08-02 1994-05-19 ファイザー・インコーポレーテッド 免疫刺激剤としてのキノリン誘導体

Also Published As

Publication number Publication date
AU2002212897A1 (en) 2002-05-15
DE60137534D1 (de) 2009-03-12
SE0004056D0 (sv) 2000-11-06
EP1339690A1 (de) 2003-09-03
JP2004513118A (ja) 2004-04-30
WO2002036569A1 (en) 2002-05-10
ES2319259T3 (es) 2009-05-06
US6841680B2 (en) 2005-01-11
US20040053965A1 (en) 2004-03-18
EP1339690B1 (de) 2009-01-21

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Legal Events

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