ATE422671T1 - Verfahren zur diagnose von morbus alzheimer - Google Patents
Verfahren zur diagnose von morbus alzheimerInfo
- Publication number
- ATE422671T1 ATE422671T1 AT03771762T AT03771762T ATE422671T1 AT E422671 T1 ATE422671 T1 AT E422671T1 AT 03771762 T AT03771762 T AT 03771762T AT 03771762 T AT03771762 T AT 03771762T AT E422671 T1 ATE422671 T1 AT E422671T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- diagnosing alzheimer
- subject
- methods
- present
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 101150037123 APOE gene Proteins 0.000 abstract 1
- 101100216294 Danio rerio apoeb gene Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40001602P | 2002-07-30 | 2002-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE422671T1 true ATE422671T1 (de) | 2009-02-15 |
Family
ID=31188657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03771762T ATE422671T1 (de) | 2002-07-30 | 2003-07-24 | Verfahren zur diagnose von morbus alzheimer |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7682795B2 (de) |
| EP (1) | EP1543331B1 (de) |
| AT (1) | ATE422671T1 (de) |
| AU (1) | AU2003259222A1 (de) |
| DE (1) | DE60326153D1 (de) |
| WO (1) | WO2004011943A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| GB2408508A (en) | 2003-11-28 | 2005-06-01 | Astrazeneca Ab | Apolipoprotein antibodies |
| US7612179B2 (en) * | 2003-11-28 | 2009-11-03 | Astrazeneca Ab | antibodies binding to a C-terminal fragment of apoliopoprotein E |
| US9335331B2 (en) * | 2005-04-11 | 2016-05-10 | Cornell Research Foundation, Inc. | Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject |
| PT1976877E (pt) | 2005-11-30 | 2014-04-29 | Abbvie Inc | Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações |
| BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| US20090136456A1 (en) * | 2006-12-22 | 2009-05-28 | Yadong Huang | Methods of treating neurodegenerative disorders |
| EP2124952A2 (de) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Verfahren zur behandlung von amyloidosen |
| US20090142766A1 (en) * | 2007-11-09 | 2009-06-04 | Washington University In St. Louis | Methods for measuring the metabolism of cns derived biomolecules in vivo |
| WO2011109246A1 (en) * | 2010-03-01 | 2011-09-09 | The J. David Gladstone Institutes | Antibody specific for apolipoprotein and methods of use thereof |
| EP2558494B1 (de) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta-bindende proteine |
| CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
| US9488666B2 (en) | 2010-08-24 | 2016-11-08 | Helena Laboratories Corporation | Assay for determination of levels of lipoprotein particles in bodily fluids |
| EP2673635A4 (de) * | 2011-02-07 | 2015-08-12 | Neotope Biosciences Ltd | Apnoe-immuntherapie |
| US10830775B2 (en) | 2014-09-30 | 2020-11-10 | Washington University | Tau kinetic measurements |
| WO2016120843A1 (en) * | 2015-01-29 | 2016-08-04 | Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa | Antibody molecules and peptide delivery systems for use in alzheimer's disease and related disorders |
| EP4685158A1 (de) * | 2024-07-22 | 2026-01-28 | Technische Universität München | Fibrilläres apolipoprotein e (apoe) zur verwendung in einem verfahren zur behandlung und/oder prävention einer neurodegenerativen erkrankung |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811310A (en) * | 1986-09-30 | 1998-09-22 | Albert Einstein College Of Medicine Of Yeshiva Univ. | The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease |
| US6287793B1 (en) * | 1988-08-19 | 2001-09-11 | Elan Pharmaceuticals, Inc. | Diagnostic methods for alzheimer's disease |
| AU2414092A (en) * | 1991-08-01 | 1993-03-02 | Paul H. Voorheis | Diagnostic method for alzheimer's disease |
| CA2086165A1 (en) * | 1992-04-09 | 1993-10-10 | Paul P. Tamburini | Diagnostic assay for alzheimer's disease based on the proteolysis of alzheimer's precursor protein |
| WO1994009371A1 (en) * | 1992-10-09 | 1994-04-28 | Massachusetts Institute Of Technology | Antemortem diagnostic test for alzheimer's disease |
| WO1994009155A1 (en) * | 1992-10-13 | 1994-04-28 | Duke University | Methods of detecting alzheimer's disease |
| US6300085B1 (en) * | 1993-05-03 | 2001-10-09 | The United States Of America As Represented By The Department Of Health And Human Services | Diagnostic method for Alzheimer's disease |
| US5849600A (en) * | 1993-11-10 | 1998-12-15 | The Mclean Hospital Corporation | Diagnostic assays for Alzheimer's disease |
| FR2716894B1 (fr) * | 1994-03-07 | 1996-05-24 | Pasteur Institut | Marqueurs génétiques utilisés conjointement pour le diagnostic de la maladie d'Alzheimer, méthode et kit de diagnostic. |
| US5976798A (en) * | 1994-03-30 | 1999-11-02 | Mitokor | Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid |
| US5972634A (en) * | 1994-10-19 | 1999-10-26 | The General Hospital Corporation | Diagnostic assay for Alzheimer's disease: assessment of Aβ abnormalities |
| US5817789A (en) * | 1995-06-06 | 1998-10-06 | Transkaryotic Therapies, Inc. | Chimeric proteins for use in transport of a selected substance into cells |
| US5976817A (en) * | 1996-10-31 | 1999-11-02 | Trustees Of Boston University | Diagnostic method for detecting Alzheimer's disease in living patients |
| US6183981B1 (en) * | 1998-03-05 | 2001-02-06 | Board Of Regents, The University Of Texas System | Diagnostic assay for late-onset Alzheimer's disease |
| JP4399160B2 (ja) * | 2000-11-03 | 2010-01-13 | ザ ジェイ． デビッド グラッドストーン インスティテューツ | ａｐｏＥに関連する疾患を治療する方法 |
| US6766817B2 (en) * | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
-
2003
- 2003-07-24 DE DE60326153T patent/DE60326153D1/de not_active Expired - Lifetime
- 2003-07-24 WO PCT/US2003/023093 patent/WO2004011943A1/en not_active Ceased
- 2003-07-24 US US10/627,447 patent/US7682795B2/en not_active Expired - Fee Related
- 2003-07-24 AU AU2003259222A patent/AU2003259222A1/en not_active Abandoned
- 2003-07-24 AT AT03771762T patent/ATE422671T1/de not_active IP Right Cessation
- 2003-07-24 EP EP03771762A patent/EP1543331B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003259222A1 (en) | 2004-02-16 |
| WO2004011943A1 (en) | 2004-02-05 |
| US7682795B2 (en) | 2010-03-23 |
| US20040157267A1 (en) | 2004-08-12 |
| EP1543331A1 (de) | 2005-06-22 |
| EP1543331B1 (de) | 2009-02-11 |
| EP1543331A4 (de) | 2006-08-02 |
| DE60326153D1 (de) | 2009-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |