ES2108698T3 - Liposomas exentos de sustancias activas, para el tratamiento de aterosclerosis. - Google Patents

Liposomas exentos de sustancias activas, para el tratamiento de aterosclerosis.

Info

Publication number
ES2108698T3
ES2108698T3 ES91109368T ES91109368T ES2108698T3 ES 2108698 T3 ES2108698 T3 ES 2108698T3 ES 91109368 T ES91109368 T ES 91109368T ES 91109368 T ES91109368 T ES 91109368T ES 2108698 T3 ES2108698 T3 ES 2108698T3
Authority
ES
Spain
Prior art keywords
atherosclerosis
treatment
active substances
liposomes
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91109368T
Other languages
English (en)
Inventor
Jurgen Dr Schmitt
Jorg Dr Nehne
Wolfgang Dr Feller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inex Pharmaceuticals Corp
Original Assignee
Inex Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inex Pharmaceuticals Corp filed Critical Inex Pharmaceuticals Corp
Application granted granted Critical
Publication of ES2108698T3 publication Critical patent/ES2108698T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION CONSISTE EN SUSTANCIA ACTIVA LIBRE, PREDOMINANDO LIPOSOMAS -FOSFOLIPIDOS UNILAMELARES COMO MEDIO DE TRATAMIENTO DE ATEROESCLEROSIS.
ES91109368T 1990-06-12 1991-06-07 Liposomas exentos de sustancias activas, para el tratamiento de aterosclerosis. Expired - Lifetime ES2108698T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4018767A DE4018767A1 (de) 1990-06-12 1990-06-12 Wirkstofffreie liposomen zur behandlung von atherosklerose

Publications (1)

Publication Number Publication Date
ES2108698T3 true ES2108698T3 (es) 1998-01-01

Family

ID=6408251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91109368T Expired - Lifetime ES2108698T3 (es) 1990-06-12 1991-06-07 Liposomas exentos de sustancias activas, para el tratamiento de aterosclerosis.

Country Status (6)

Country Link
EP (1) EP0461559B1 (es)
AT (1) ATE157876T1 (es)
DE (2) DE4018767A1 (es)
DK (1) DK0461559T3 (es)
ES (1) ES2108698T3 (es)
GR (1) GR3025368T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231090A (en) * 1990-07-30 1993-07-27 University Of Miami Treatment for hypercholesterolemia
AU1751795A (en) * 1994-03-04 1995-09-18 University Of British Columbia, The Liposome compositions and methods for the treatment of atherosclerosis
US6312719B1 (en) 1994-03-04 2001-11-06 The University Of British Columbia Liposome compositions and methods for the treatment of atherosclerosis
US5746223A (en) 1996-10-11 1998-05-05 Williams; Kevin Jon Method of forcing the reverse transport of cholesterol from a body part to the liver while avoiding harmful disruptions of hepatic cholesterol homeostasis
US6139871A (en) * 1995-07-26 2000-10-31 The University Of British Columbia Liposome compositions and methods for the treatment of atherosclerosis
US6773719B2 (en) 1994-03-04 2004-08-10 Esperion Luv Development, Inc. Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias
EP0767655B1 (en) * 1994-06-10 2004-08-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of treating hypertension
IL123509A (en) * 1995-08-31 2007-05-15 Yissum Res Dev Co Therapeutic lipoprotein composition containing lipid vesicles which bind apoproteins and uses therof
CA2231547A1 (en) * 1995-10-11 1997-04-17 Kevin Jon Williams Liposomal compositions and methods of using them
FR2764507B1 (fr) * 1997-06-11 2000-10-20 Lipogel Sarl Compositions pulverulentes de liposomes unilamellaires, leur procede de preparation et leurs applications comme complements nutritionnels et comme complements nutritionnels et comme medicaments
RU2128991C1 (ru) * 1998-06-23 1999-04-20 Общество с ограниченной ответственностью "ЭМУ-Темп" Биологически активный эмульсионный препарат
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
US20040009216A1 (en) * 2002-04-05 2004-01-15 Rodrigueza Wendi V. Compositions and methods for dosing liposomes of certain sizes to treat or prevent disease
US8697120B2 (en) 2006-05-01 2014-04-15 Johns Hopkins University Method and use of nano-scale devices for reduction of tissue injury in ischemic and reperfusion injury
WO2008106772A1 (en) * 2007-03-07 2008-09-12 Liponex, Inc. Phospholipid compositions with improved bioavailability and methods for their use
EP3632403A4 (en) * 2017-05-23 2021-03-10 TCI Co., Ltd. EMULSIFIED LIPOSOME COMPOSITION AND PROCESS FOR PREPARATION

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
EP0152379A3 (de) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
EP0190343A1 (en) * 1984-08-28 1986-08-13 MIXSON, A. James Method for using nutrient-containing liposomes in hyperalimentation
US4812314A (en) * 1986-02-24 1989-03-14 Yissum Research & Dev. Co. Of The Hebrew Univ. Of Jerusalem And Hadassah Medical Organization Lipid replacement therapy
DE3815473A1 (de) * 1988-05-06 1989-11-16 Karl Heinz Prof Dr Dr Schmidt Wirkstoff-system fuer den lipidaustausch mit zielstrukturen

Also Published As

Publication number Publication date
EP0461559A3 (en) 1992-07-08
GR3025368T3 (en) 1998-02-27
DE59108850D1 (de) 1997-10-16
DE4018767A1 (de) 1991-12-19
EP0461559B1 (de) 1997-09-10
ATE157876T1 (de) 1997-09-15
DK0461559T3 (da) 1998-04-27
EP0461559A2 (de) 1991-12-18

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