ATE423788T1 - Neues tgf-beta-ahnliches cytokin - Google Patents

Neues tgf-beta-ahnliches cytokin

Info

Publication number: ATE423788T1
Authority: AT; Austria
Prior art keywords: cytokine; beta; new tgf; pcl13; tgf
Prior art date: 1995-06-22

Application number

AT96918521T

Other languages

English (en)

Inventor

Samuel Breit

Michelle Bootcov

Original Assignee

St Vincents Hosp Sydney

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-22

Filing date

1996-06-24

Publication date

2009-03-15

1995-06-22 Priority claimed from AUPN3706A external-priority patent/AUPN370695A0/en

1995-08-23 Priority claimed from AUPN4990A external-priority patent/AUPN499095A0/en

1996-02-09 Priority claimed from AUPN7983A external-priority patent/AUPN798396A0/en

1996-06-24 Application filed by St Vincents Hosp Sydney filed Critical St Vincents Hosp Sydney

2009-03-15 Application granted granted Critical

2009-03-15 Publication of ATE423788T1 publication Critical patent/ATE423788T1/de

Links

102000004127 Cytokines Human genes 0.000 title abstract 2
108090000695 Cytokines Proteins 0.000 title abstract 2
239000012634 fragment Substances 0.000 abstract 2
102000040430 polynucleotide Human genes 0.000 abstract 2
108091033319 polynucleotide Proteins 0.000 abstract 2
239000002157 polynucleotide Substances 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT96918521T 1995-06-22 1996-06-24 Neues tgf-beta-ahnliches cytokin ATE423788T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AUPN3706A AUPN370695A0 (en)	1995-06-22	1995-06-22	Novel cytokine
AUPN4990A AUPN499095A0 (en)	1995-08-23	1995-08-23	Novel cytokine
AUPN7983A AUPN798396A0 (en)	1996-02-09	1996-02-09	Novel cytokine

Publications (1)

Publication Number	Publication Date
ATE423788T1 true ATE423788T1 (de)	2009-03-15

Family

ID=27157870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96918521T ATE423788T1 (de)	1995-06-22	1996-06-24	Neues tgf-beta-ahnliches cytokin

Country Status (7)

Country	Link
EP (1)	EP0833912B1 (de)
AT (1)	ATE423788T1 (de)
CA (1)	CA2225377C (de)
DE (1)	DE69637844D1 (de)
ES (1)	ES2324433T3 (de)
NZ (1)	NZ310370A (de)
WO (1)	WO1997000958A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180602B1 (en)	1992-08-04	2001-01-30	Sagami Chemical Research Center	Human novel cDNA, TGF-beta superfamily protein encoded thereby and the use of immunosuppressive agent
US5994102A (en)	1994-12-15	1999-11-30	Human Genome Sciences, Inc.	Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
US6521227B1 (en)	1999-11-18	2003-02-18	Peter L. Hudson	Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
US6524802B1 (en) *	1996-03-29	2003-02-25	The Johns Hopkins University School Of Medicine	Methods of detecting growth differentiation factor-14
WO1998011224A1 (en) *	1996-09-11	1998-03-19	Ortho-Mcneil Pharmaceutical,Inc	Tnf-beta-like protein for treating prostate cancer, and related nucleic acid molecules, pharmaceutical compositions and methods
US6465181B2 (en) *	1999-03-25	2002-10-15	Abbott Laboratories	Reagents and methods useful for detecting diseases of the prostate
ATE348164T1 (de) *	1999-05-17	2007-01-15	Bioph Biotech Entw Pharm Gmbh	Neuroprotektive eigenschaften von gdf-15, ein mitglied der tgf-beta superfamilie
EP1914554B1 (de) *	2000-04-20	2010-06-09	St Vincent's Hospital Sydney Limited	Diagnostischer Assay mit makrophagenhemmendem Zytokin-1 (MIC-1)
SE0002364D0 (sv) *	2000-06-22	2000-06-22	Pharmacia & Upjohn Ab	Growth Factors
WO2002020759A2 (en) *	2000-09-08	2002-03-14	The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	A non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
CA2390820A1 (en)	2002-06-17	2003-12-17	St. Vincent's Hospital Sydney Limited	Methods of diagnosis, prognosis and treatment of cardiovascular disease
US7919084B2 (en)	2002-06-17	2011-04-05	St. Vincent's Hospital Sydney Limited	Methods of diagnosis, prognosis and treatment of cardiovascular disease
US20050191668A1 (en) *	2004-01-14	2005-09-01	Lubing Zhou	Methods of using peroxisome proliferator-activated receptor alpha target genes
ES2518865T3 (es)	2004-04-13	2014-11-05	St Vincent's Hospital Sydney Limited	Agente de inhibición de MIC-1
WO2005116052A2 (en)	2004-04-27	2005-12-08	Research Development Foundation	ANTAGONISM OF TGF-β SUPERFAMILY RECEPTOR SIGNALING
US20070237713A1 (en)	2006-04-04	2007-10-11	Fan Rong A	PCan065 Antibody Compositions and Methods of Use
JP5444363B2 (ja)	2008-10-31	2014-03-19	セントビンセンツホスピタルシドニーリミテッド	慢性腎疾患における予後判定の方法
WO2010144696A1 (en)	2009-06-11	2010-12-16	Burnham Institute For Medical Research	Directed differentiation of stem cells
US9550819B2 (en)	2012-03-27	2017-01-24	Ngm Biopharmaceuticals, Inc.	Compositions and methods of use for treating metabolic disorders
CA2896076C (en)	2012-12-21	2022-12-06	Aveo Pharmaceuticals, Inc.	Anti-gdf15 antibodies
US9161966B2 (en)	2013-01-30	2015-10-20	Ngm Biopharmaceuticals, Inc.	GDF15 mutein polypeptides
EP2950807B1 (de)	2013-01-30	2018-03-28	NGM Biopharmaceuticals, Inc.	Zusammensetzungen und verfahren zur verwendung bei der behandlung von stoffwechselerkrankungen
US10588980B2 (en)	2014-06-23	2020-03-17	Novartis Ag	Fatty acids and their use in conjugation to biomolecules
TN2016000578A1 (en)	2014-07-30	2018-04-04	Ngm Biopharmaceuticals Inc	Compositions and methods of use for treating metabolic disorders
EP3212226B1 (de)	2014-10-31	2020-03-18	NGM Biopharmaceuticals, Inc.	Zusammensetzungen und verfahren zur verwendung zur behandlung von stoffwechselerkrankungen
CN108367053A (zh)	2015-12-22	2018-08-03	诺华股份有限公司	使用生长分化因子15(gdf-15)治疗或改善代谢性疾病的方法
WO2017172260A1 (en)	2016-03-31	2017-10-05	Ngm Bioparmaceuticals, Inc.	Binding proteins and methods of use thereof
CA3045700A1 (en)	2016-12-06	2018-06-14	St Vincent's Hospital Sydney Limited	Treatment of obesity and eating disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994003599A1 (fr) *	1992-08-04	1994-02-17	Sagami Chemical Research Center	ADNc HUMAIN ET PROTEINE POUR LAQUELLE CODE CET ADNc
WO1995014772A1 (en) *	1993-11-12	1995-06-01	Kenichi Matsubara	Gene signature
JPH07250688A (ja) *	1994-01-28	1995-10-03	Sagami Chem Res Center	ＴＧＦ−βスーパーファミリー蛋白質をコードするヒト新規ｃＤＮＡ
JPH07258293A (ja) *	1994-03-23	1995-10-09	Asahi Chem Ind Co Ltd	新規な蛋白質ならびにその製造方法
AU1830195A (en) *	1994-12-15	1996-07-03	Human Genome Sciences, Inc.	Prostatic growth factor
US6524802B1 (en) *	1996-03-29	2003-02-25	The Johns Hopkins University School Of Medicine	Methods of detecting growth differentiation factor-14

1996
- 1996-06-24 EP EP96918521A patent/EP0833912B1/de not_active Expired - Lifetime
- 1996-06-24 ES ES96918521T patent/ES2324433T3/es not_active Expired - Lifetime
- 1996-06-24 NZ NZ310370A patent/NZ310370A/en not_active IP Right Cessation
- 1996-06-24 AT AT96918521T patent/ATE423788T1/de active
- 1996-06-24 DE DE69637844T patent/DE69637844D1/de not_active Expired - Lifetime
- 1996-06-24 WO PCT/AU1996/000386 patent/WO1997000958A1/en not_active Ceased
- 1996-06-24 CA CA2225377A patent/CA2225377C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2225377A1 (en)	1997-01-09
EP0833912A4 (de)	2002-10-02
EP0833912A1 (de)	1998-04-08
EP0833912B1 (de)	2009-02-25
WO1997000958A1 (en)	1997-01-09
DE69637844D1 (de)	2009-04-09
NZ310370A (en)	2001-04-27
ES2324433T3 (es)	2009-08-06
CA2225377C (en)	2013-08-13

Legal Events

Date

Code

Title

Description

2009-11-15

UEP

Publication of translation of european patent specification

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