ATE423788T1 - Neues tgf-beta-ahnliches cytokin - Google Patents

Neues tgf-beta-ahnliches cytokin

Info

Publication number: ATE423788T1
Authority: AT; Austria
Prior art keywords: cytokine; beta; new tgf; pcl13; tgf
Prior art date: 1995-06-22

Application number

AT96918521T

Other languages

English (en)

Inventor

Samuel Breit

Michelle Bootcov

Original Assignee

St Vincents Hosp Sydney

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-22

Filing date

1996-06-24

Publication date

2009-03-15

1995-06-22 Priority claimed from AUPN3706A external-priority patent/AUPN370695A0/en

1995-08-23 Priority claimed from AUPN4990A external-priority patent/AUPN499095A0/en

1996-02-09 Priority claimed from AUPN7983A external-priority patent/AUPN798396A0/en

1996-06-24 Application filed by St Vincents Hosp Sydney filed Critical St Vincents Hosp Sydney

2009-03-15 Application granted granted Critical

2009-03-15 Publication of ATE423788T1 publication Critical patent/ATE423788T1/de

Links

102000004127 Cytokines Human genes 0.000 title abstract 2
108090000695 Cytokines Proteins 0.000 title abstract 2
239000012634 fragment Substances 0.000 abstract 2
102000040430 polynucleotide Human genes 0.000 abstract 2
108091033319 polynucleotide Proteins 0.000 abstract 2
239000002157 polynucleotide Substances 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT96918521T 1995-06-22 1996-06-24 Neues tgf-beta-ahnliches cytokin ATE423788T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AUPN3706A AUPN370695A0 (en)	1995-06-22	1995-06-22	Novel cytokine
AUPN4990A AUPN499095A0 (en)	1995-08-23	1995-08-23	Novel cytokine
AUPN7983A AUPN798396A0 (en)	1996-02-09	1996-02-09	Novel cytokine

Publications (1)

Publication Number	Publication Date
ATE423788T1 true ATE423788T1 (de)	2009-03-15

Family

ID=27157870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96918521T ATE423788T1 (de)	1995-06-22	1996-06-24	Neues tgf-beta-ahnliches cytokin

Country Status (7)

Country	Link
EP (1)	EP0833912B1 (de)
AT (1)	ATE423788T1 (de)
CA (1)	CA2225377C (de)
DE (1)	DE69637844D1 (de)
ES (1)	ES2324433T3 (de)
NZ (1)	NZ310370A (de)
WO (1)	WO1997000958A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180602B1 (en)	1992-08-04	2001-01-30	Sagami Chemical Research Center	Human novel cDNA, TGF-beta superfamily protein encoded thereby and the use of immunosuppressive agent
US6521227B1 (en)	1999-11-18	2003-02-18	Peter L. Hudson	Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
US5994102A (en) *	1994-12-15	1999-11-30	Human Genome Sciences, Inc.	Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
US6524802B1 (en) *	1996-03-29	2003-02-25	The Johns Hopkins University School Of Medicine	Methods of detecting growth differentiation factor-14
JP2001500732A (ja) *	1996-09-11	2001-01-23	オーソ―マクニール・フアーマシユーチカル・インコーポレーテツド	前立腺がんを治療するためのＴＮＦ―β様タンパク質、ならびに関連する核酸分子、医薬組成物および方法
US6465181B2 (en) *	1999-03-25	2002-10-15	Abbott Laboratories	Reagents and methods useful for detecting diseases of the prostate
JP2002543841A (ja) *	1999-05-17	2002-12-24	バイオファームゲゼルシャフトツアバイオテクノロジシェンエントヴィックルングウントツムフェルトリーブフォンファルマカエムベーハー	ＴＧＦ−βスーパーファミリーの新規のメンバーであるＧＤＦ―１５の神経保護特性
ATE470863T1 (de) *	2000-04-20	2010-06-15	St Vincents Hosp Sydney	Diagnostischer assay mit makrophagenhemmendem zytokin-1 (mic-1)
SE0002364D0 (sv) *	2000-06-22	2000-06-22	Pharmacia & Upjohn Ab	Growth Factors
AU2001288770A1 (en) *	2000-09-08	2002-03-22	The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services	A non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
CA2390820A1 (en)	2002-06-17	2003-12-17	St. Vincent's Hospital Sydney Limited	Methods of diagnosis, prognosis and treatment of cardiovascular disease
US7919084B2 (en)	2002-06-17	2011-04-05	St. Vincent's Hospital Sydney Limited	Methods of diagnosis, prognosis and treatment of cardiovascular disease
JP2007522803A (ja) *	2004-01-14	2007-08-16	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	ペルオキシソーム増殖因子活性化受容体アルファ標的遺伝子を使用する方法
EP2441466B1 (de)	2004-04-13	2014-07-23	St Vincent's Hospital Sydney Limited	MIC-1 inhibierendes Mittel
EP1740609A2 (de)	2004-04-27	2007-01-10	Research Development Foundation	Antagonismus des tgf-beta superfamily signal rezeptors
US20070237713A1 (en)	2006-04-04	2007-10-11	Fan Rong A	PCan065 Antibody Compositions and Methods of Use
JP5444363B2 (ja)	2008-10-31	2014-03-19	セントビンセンツホスピタルシドニーリミテッド	慢性腎疾患における予後判定の方法
WO2010144696A1 (en)	2009-06-11	2010-12-16	Burnham Institute For Medical Research	Directed differentiation of stem cells
CA2862516C (en)	2012-03-27	2023-02-14	Ngm Biopharmaceuticals, Inc.	Compositions and methods of use for treating metabolic disorders
ES2791183T3 (es)	2012-12-21	2020-11-03	Aveo Pharmaceuticals Inc	Anticuerpos anti-GDF15
KR101993714B1 (ko)	2013-01-30	2019-06-28	엔지엠 바이오파마슈티컬스, 아이엔씨.	대사 장애를 치료하는데 이용하기 위한 조성물과 방법
US9161966B2 (en)	2013-01-30	2015-10-20	Ngm Biopharmaceuticals, Inc.	GDF15 mutein polypeptides
US10588980B2 (en)	2014-06-23	2020-03-17	Novartis Ag	Fatty acids and their use in conjugation to biomolecules
AU2015296640B2 (en)	2014-07-30	2020-05-21	Ngm Biopharmaceuticals, Inc.	Compositions and methods of use for treating metabolic disorders
EP3701969A1 (de)	2014-10-31	2020-09-02	NGM Biopharmaceuticals, Inc.	Zusammensetzungen und verfahren zur verwendung zur behandlung von stoffwechselerkrankungen
JP6946304B2 (ja)	2015-12-22	2021-10-06	ノバルティスアーゲー	増殖分化因子１５（ｇｄｆ−１５）を使用して代謝障害を処置するまたは軽快させる方法
MY194669A (en)	2016-03-31	2022-12-12	Ngm Biopharmaceuticals Inc	Binding Proteins and Methods of use Thereof
US20200069774A1 (en)	2016-12-06	2020-03-05	St Vincent's Hospital Sydney Limited	Treatment of obesity and eating disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994003599A1 (fr) *	1992-08-04	1994-02-17	Sagami Chemical Research Center	ADNc HUMAIN ET PROTEINE POUR LAQUELLE CODE CET ADNc
EP0679716A4 (de) *	1993-11-12	1999-06-09	Kenichi Matsubara	Genetische Signaturen.
JPH07250688A (ja) *	1994-01-28	1995-10-03	Sagami Chem Res Center	ＴＧＦ−βスーパーファミリー蛋白質をコードするヒト新規ｃＤＮＡ
JPH07258293A (ja) *	1994-03-23	1995-10-09	Asahi Chem Ind Co Ltd	新規な蛋白質ならびにその製造方法
WO1996018730A1 (en) *	1994-12-15	1996-06-20	Human Genome Sciences, Inc.	Prostatic growth factor
US6524802B1 (en) *	1996-03-29	2003-02-25	The Johns Hopkins University School Of Medicine	Methods of detecting growth differentiation factor-14

1996
- 1996-06-24 ES ES96918521T patent/ES2324433T3/es not_active Expired - Lifetime
- 1996-06-24 DE DE69637844T patent/DE69637844D1/de not_active Expired - Lifetime
- 1996-06-24 WO PCT/AU1996/000386 patent/WO1997000958A1/en not_active Ceased
- 1996-06-24 AT AT96918521T patent/ATE423788T1/de active
- 1996-06-24 CA CA2225377A patent/CA2225377C/en not_active Expired - Lifetime
- 1996-06-24 NZ NZ310370A patent/NZ310370A/en not_active IP Right Cessation
- 1996-06-24 EP EP96918521A patent/EP0833912B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2225377A1 (en)	1997-01-09
CA2225377C (en)	2013-08-13
NZ310370A (en)	2001-04-27
ES2324433T3 (es)	2009-08-06
DE69637844D1 (de)	2009-04-09
EP0833912A4 (de)	2002-10-02
EP0833912B1 (de)	2009-02-25
WO1997000958A1 (en)	1997-01-09
EP0833912A1 (de)	1998-04-08

Legal Events

Date

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Title

Description

2009-11-15

UEP

Publication of translation of european patent specification

Ref document number: 0833912

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Publication	Publication Date	Title
DE69637844D1 (de)	2009-04-09	Neues tgf-beta-ahnliches cytokin
DK1009832T3 (da)	2007-02-12	Cytokin betegnet LERK-6
DE69027990D1 (de)	1996-09-05	Kultur des wachstumsfaktors der vaskularen endothelialzellen und dns, die dafür kodiert
EP1019365A4 (de)	2001-01-17	Zubereitungen zur abgabe von negativ geladenen molekülen
ATE271058T1 (de)	2004-07-15	Mycophenol bisphosponatverbindungen
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DK1149905T3 (da)	2010-11-01	Fremgangsmåder og præparat til polypeptidteknologi
ATE114169T1 (de)	1994-12-15	Morphogenetisches knochenprotein.
ES2101499T3 (es)	1997-07-01	Fibras.
MXPA02004666A (es)	2003-06-24	Gelatinas recombinantes.
NO960767D0 (no)	1996-02-26	Protocadherinproteiner og deres anvendelse
GR890100846A (el)	1991-03-15	Μεθοδος μετατροπης κυτταρικης διαφοροποιησης και λειτουργιας καισυνθεσεις της.
HUT77049A (hu)	1998-03-02	Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok
EA200000196A1 (ru)	2000-10-30	Универсальная плазма крови
FI962247L (fi)	1996-07-22	Uudet apoptoosia muuntavat proteiinit, niitä koodaava DNA ja näiden käyttömenetelmät
DE59410132D1 (de)	2002-07-11	Humanes zirkulierendes cytokin cc-1
DK0785716T3 (da)	2007-04-02	Cytokin betegnet LERK-6
ATE291586T1 (de)	2005-04-15	Humanes antibiotisches protein
ATE341339T1 (de)	2006-10-15	Zusammensetzungen von rekombinanten papillomavirus vakzinen
DK0939769T3 (da)	2006-03-13	Vertebrat-Smoothened-proteiner
KR950700988A (ko)	1995-02-20	미생물, 이들의 제조방법 및 이들의 사용(Micro-organisms, preparation method therefor and uses thereof)
DK0952982T3 (da)	2004-03-29	Hidtil ukendte hepatitis B inhibitorer
WO2001064840A8 (en)	2002-03-21	Novel bone marrow nucleic acids and polypeptides
ITMI931034A1 (it)	1994-11-21	Processo per la preparazione di proteine inibenti i ribosomi
WO1994021273A3 (de)	1994-12-08	VERWENDUNG VON ANGIOGENIN UND/ODER α1-MICROGLOBULIN UND/ODER KOMPLEMENTFAKTOR D ZUR BEGRENZUNG DER SEKRETION VON PROTEINEN