ATE424224T1 - Dezellularisierung von gewebematrixen - Google Patents

Dezellularisierung von gewebematrixen

Info

Publication number
ATE424224T1
ATE424224T1 AT02735577T AT02735577T ATE424224T1 AT E424224 T1 ATE424224 T1 AT E424224T1 AT 02735577 T AT02735577 T AT 02735577T AT 02735577 T AT02735577 T AT 02735577T AT E424224 T1 ATE424224 T1 AT E424224T1
Authority
AT
Austria
Prior art keywords
decellularization
tissue
implantation
matrices
matrixes
Prior art date
Application number
AT02735577T
Other languages
English (en)
Inventor
John Fisher
Catherine Booth
Eileen Ingham
Original Assignee
Univ Leeds
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leeds filed Critical Univ Leeds
Application granted granted Critical
Publication of ATE424224T1 publication Critical patent/ATE424224T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Magnetic Ceramics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Inorganic Insulating Materials (AREA)
AT02735577T 2001-05-24 2002-05-20 Dezellularisierung von gewebematrixen ATE424224T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0112586A GB2375771A (en) 2001-05-24 2001-05-24 Decellularisation of tissue implant material

Publications (1)

Publication Number Publication Date
ATE424224T1 true ATE424224T1 (de) 2009-03-15

Family

ID=9915172

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735577T ATE424224T1 (de) 2001-05-24 2002-05-20 Dezellularisierung von gewebematrixen

Country Status (9)

Country Link
US (1) US7354749B2 (de)
EP (1) EP1392372B1 (de)
AT (1) ATE424224T1 (de)
AU (1) AU2002310589B2 (de)
CA (1) CA2447847C (de)
DE (1) DE60231395D1 (de)
ES (1) ES2322891T3 (de)
GB (1) GB2375771A (de)
WO (1) WO2002096476A1 (de)

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US20050013870A1 (en) * 2003-07-17 2005-01-20 Toby Freyman Decellularized extracellular matrix of conditioned body tissues and uses thereof
DE102004047247B3 (de) * 2004-09-22 2006-03-16 Auto Tissue Gmbh Sterilisationsverfahren zur Herstellung von implantierbarem oder transplantierbarem biologischem Material
ATE552007T1 (de) * 2005-08-26 2012-04-15 Univ Minnesota Dezellularisierung und rezellularisierung von organen und geweben
US20100093066A1 (en) * 2005-08-26 2010-04-15 Regents Of The University Of Minnesota Decellularization and recellularization apparatuses and systems containing the same
GB0606231D0 (en) * 2006-03-29 2006-05-10 Univ Leeds Improvements relating to decellurisation of tissue matrices for bladder implantation
CN103933612B (zh) * 2006-10-27 2016-06-22 爱德华兹生命科学公司 用于外科植入的生物组织
JP5732197B2 (ja) * 2006-11-16 2015-06-10 ユニヴァーシティ・オヴ・リーズ 半月板インプランテーションのための組織の調製
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
JP2009050297A (ja) * 2007-08-23 2009-03-12 Tokyo Medical & Dental Univ 脱細胞処理液、脱細胞化組織の調製方法、移植片、及び培養部材
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
FR2951549B1 (fr) 2009-10-15 2013-08-23 Olivier Schussler Procede d'obtention de bioprotheses medicales implantables
US20110165676A1 (en) * 2009-11-06 2011-07-07 The Children's Mercy Hospital Method for decellularization
ES2719816T3 (es) 2010-02-26 2019-07-16 Decell Tech Inc Métodos para la descelularización de tejidos
EP3636293A1 (de) 2010-03-23 2020-04-15 Edwards Lifesciences Corporation Verfahren zur bearbeitung eines scheibenförmigen bioprothese-gewebes
CA2794135C (en) * 2010-06-17 2018-01-02 Edwards Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US8906601B2 (en) * 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
SG188369A1 (en) 2010-09-01 2013-04-30 Univ Minnesota Methods of recellularizing a tissue or organ for improved transplantability
ES2628441T3 (es) * 2010-09-27 2017-08-02 Tissue Regenix Limited Productos vasculares acelulares
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
RU2499611C1 (ru) * 2012-09-28 2013-11-27 Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) Способ повышения биосовместимости трансплантатов клапанов сердца и сосудов
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
KR102278652B1 (ko) 2013-03-15 2021-07-19 미로매트릭스 메디칼 인크. 섬 세포 재세포화를 위한 관류 탈세포화된 간의 용도
EP3027235A1 (de) 2013-07-30 2016-06-08 Musculoskeletal Transplant Foundation Aus einem azellulären weichgewebe gewonnene matrizen und verfahren zur herstellung davon
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
ES2846758T3 (es) 2013-11-04 2021-07-29 Lifecell Corp Métodos para eliminar la alfa-galactosa
RU2586952C1 (ru) * 2015-07-20 2016-06-10 Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации Способ лечения печеночной недостаточности
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN105709276B (zh) * 2016-01-28 2018-08-10 成都清科生物科技有限公司 一种绒毛膜脱细胞液以及脱细胞方法
EP3509651B1 (de) 2016-09-06 2022-12-28 Miromatrix Medical Inc. Verwendung von reseziertem leberserum zum engineering der ganzen leber
CA3062547A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
CN107596446B (zh) * 2017-09-16 2020-07-28 温州医科大学 一种维持组织超微结构和营养微环境的脱细胞试剂盒
WO2019147585A1 (en) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
RU2678966C1 (ru) * 2018-04-03 2019-02-05 ООО "БиоИн-М" Способ повышения биосовместимости перикардиальных биоматериалов для реконструктивной хирургии
US12263275B2 (en) 2018-06-13 2025-04-01 Miromatrix Medical Inc. Fistula filler and deployment system
CN109260517B (zh) * 2018-09-19 2020-10-30 杭州启明医疗器械股份有限公司 一种可预装干燥生物心脏瓣膜及其制备方法
WO2020092205A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
AU2020399770B2 (en) 2019-12-09 2026-03-12 Edwards Lifesciences Corporation Bioprosthetic tissue preparation
GB202003210D0 (en) 2020-03-05 2020-04-22 Tissue Regenix Ltd A method for producing a decellularized tissue scaffold
US11998662B1 (en) 2021-06-09 2024-06-04 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
US12383657B1 (en) 2021-06-09 2025-08-12 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
CN113368313B (zh) * 2021-06-10 2022-06-03 吾奇生物医疗科技(江苏)有限公司 一种生物膜的制备方法及其产品和应用
CN115006594B (zh) * 2022-06-26 2023-07-11 中国海洋大学 机械增强型脱细胞猪角膜后板层载体支架制备方法及应用
CN115453021B (zh) * 2022-08-15 2023-11-14 首都医科大学附属北京友谊医院 一种sds脱细胞溶液及其在脱细胞处理或细胞外基质不可溶组分鉴定中的应用

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Also Published As

Publication number Publication date
WO2002096476A1 (en) 2002-12-05
AU2002310589B2 (en) 2007-01-25
CA2447847A1 (en) 2002-12-05
DE60231395D1 (de) 2009-04-16
EP1392372A1 (de) 2004-03-03
CA2447847C (en) 2011-11-22
GB2375771A (en) 2002-11-27
US7354749B2 (en) 2008-04-08
GB0112586D0 (en) 2001-07-18
EP1392372B1 (de) 2009-03-04
ES2322891T3 (es) 2009-07-01
US20040157206A1 (en) 2004-08-12

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