ATE424224T1 - Dezellularisierung von gewebematrixen - Google Patents

Dezellularisierung von gewebematrixen

Info

Publication number
ATE424224T1
ATE424224T1 AT02735577T AT02735577T ATE424224T1 AT E424224 T1 ATE424224 T1 AT E424224T1 AT 02735577 T AT02735577 T AT 02735577T AT 02735577 T AT02735577 T AT 02735577T AT E424224 T1 ATE424224 T1 AT E424224T1
Authority
AT
Austria
Prior art keywords
decellularization
tissue
implantation
matrices
matrixes
Prior art date
Application number
AT02735577T
Other languages
English (en)
Inventor
John Fisher
Catherine Booth
Eileen Ingham
Original Assignee
Univ Leeds
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leeds filed Critical Univ Leeds
Application granted granted Critical
Publication of ATE424224T1 publication Critical patent/ATE424224T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Inorganic Insulating Materials (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Ceramics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AT02735577T 2001-05-24 2002-05-20 Dezellularisierung von gewebematrixen ATE424224T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0112586A GB2375771A (en) 2001-05-24 2001-05-24 Decellularisation of tissue implant material

Publications (1)

Publication Number Publication Date
ATE424224T1 true ATE424224T1 (de) 2009-03-15

Family

ID=9915172

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735577T ATE424224T1 (de) 2001-05-24 2002-05-20 Dezellularisierung von gewebematrixen

Country Status (9)

Country Link
US (1) US7354749B2 (de)
EP (1) EP1392372B1 (de)
AT (1) ATE424224T1 (de)
AU (1) AU2002310589B2 (de)
CA (1) CA2447847C (de)
DE (1) DE60231395D1 (de)
ES (1) ES2322891T3 (de)
GB (1) GB2375771A (de)
WO (1) WO2002096476A1 (de)

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US20050013870A1 (en) * 2003-07-17 2005-01-20 Toby Freyman Decellularized extracellular matrix of conditioned body tissues and uses thereof
DE102004047247B3 (de) * 2004-09-22 2006-03-16 Auto Tissue Gmbh Sterilisationsverfahren zur Herstellung von implantierbarem oder transplantierbarem biologischem Material
US20100093066A1 (en) * 2005-08-26 2010-04-15 Regents Of The University Of Minnesota Decellularization and recellularization apparatuses and systems containing the same
MX369594B (es) 2005-08-26 2019-11-13 Univ Minnesota Descelularizacion y recelularizacion de organos y tejidos.
GB0606231D0 (en) * 2006-03-29 2006-05-10 Univ Leeds Improvements relating to decellurisation of tissue matrices for bladder implantation
US8007992B2 (en) * 2006-10-27 2011-08-30 Edwards Lifesciences Corporation Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C1-C3 alcohol
US8956411B2 (en) * 2006-11-16 2015-02-17 University Of Leeds Preparation of tissue for meniscal implantation
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
JP2009050297A (ja) * 2007-08-23 2009-03-12 Tokyo Medical & Dental Univ 脱細胞処理液、脱細胞化組織の調製方法、移植片、及び培養部材
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
FR2951549B1 (fr) 2009-10-15 2013-08-23 Olivier Schussler Procede d'obtention de bioprotheses medicales implantables
US20110165676A1 (en) * 2009-11-06 2011-07-07 The Children's Mercy Hospital Method for decellularization
CA2791158C (en) 2010-02-26 2020-07-21 Decell Technologies Inc. Methods for tissue decellularization
BR122014006876B1 (pt) 2010-03-23 2020-09-29 Edwards Lifesciences Corporation Método para preparar material de membrana de tecido bioprotético
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
CN102946916B (zh) 2010-06-17 2015-03-18 爱德华兹生命科学公司 通过化学修饰抗原性碳水化合物稳定生物假体组织的方法
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
RU2611361C2 (ru) 2010-09-01 2017-02-21 Риджентс Оф Дзе Юниверсити Оф Миннесота Способы рецеллюляризации ткани или органа для улучшения приживления трансплантата
US9510933B2 (en) 2010-09-27 2016-12-06 Tissue Regenix Limited Acellular vascular products
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
RU2499611C1 (ru) * 2012-09-28 2013-11-27 Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) Способ повышения биосовместимости трансплантатов клапанов сердца и сосудов
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
JP2016513465A (ja) 2013-03-15 2016-05-16 ミロマトリックス メディカル インコーポレイティド 膵島細胞の再細胞化のための灌流型脱細胞化肝臓の使用
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
WO2015066668A1 (en) 2013-11-04 2015-05-07 Lifecell Corporation Methods of removing alpha-galactose
RU2586952C1 (ru) * 2015-07-20 2016-06-10 Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации Способ лечения печеночной недостаточности
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN105709276B (zh) * 2016-01-28 2018-08-10 成都清科生物科技有限公司 一种绒毛膜脱细胞液以及脱细胞方法
US11278643B2 (en) 2016-09-06 2022-03-22 Mayo Foundation For Medical Education And Research Use of resected liver serum for whole liver-engineering
CA3062547A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
CN107596446B (zh) * 2017-09-16 2020-07-28 温州医科大学 一种维持组织超微结构和营养微环境的脱细胞试剂盒
EP3743124B1 (de) 2018-01-23 2024-05-08 Edwards Lifesciences Corporation Verfahren zum vordehnen von implantierbaren biokompatiblen materialien sowie daraus hergestellte materialien und vorrichtungen
RU2678966C1 (ru) * 2018-04-03 2019-02-05 ООО "БиоИн-М" Способ повышения биосовместимости перикардиальных биоматериалов для реконструктивной хирургии
WO2019241499A1 (en) 2018-06-13 2019-12-19 Miromatrix Medical Inc. Fistula filler and deployment system
CN109260517B (zh) * 2018-09-19 2020-10-30 杭州启明医疗器械股份有限公司 一种可预装干燥生物心脏瓣膜及其制备方法
CA3116158A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
EP3965841A1 (de) 2019-12-09 2022-03-16 Edwards Lifesciences Corporation Bioprothetische gewebepräparation
GB202003210D0 (en) 2020-03-05 2020-04-22 Tissue Regenix Ltd A method for producing a decellularized tissue scaffold
US11998662B1 (en) 2021-06-09 2024-06-04 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
US12383657B1 (en) 2021-06-09 2025-08-12 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
CN113368313B (zh) * 2021-06-10 2022-06-03 吾奇生物医疗科技(江苏)有限公司 一种生物膜的制备方法及其产品和应用
CN115006594B (zh) * 2022-06-26 2023-07-11 中国海洋大学 机械增强型脱细胞猪角膜后板层载体支架制备方法及应用
CN115453021B (zh) * 2022-08-15 2023-11-14 首都医科大学附属北京友谊医院 一种sds脱细胞溶液及其在脱细胞处理或细胞外基质不可溶组分鉴定中的应用

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Also Published As

Publication number Publication date
CA2447847A1 (en) 2002-12-05
WO2002096476A1 (en) 2002-12-05
CA2447847C (en) 2011-11-22
EP1392372B1 (de) 2009-03-04
GB0112586D0 (en) 2001-07-18
EP1392372A1 (de) 2004-03-03
DE60231395D1 (de) 2009-04-16
US7354749B2 (en) 2008-04-08
ES2322891T3 (es) 2009-07-01
AU2002310589B2 (en) 2007-01-25
US20040157206A1 (en) 2004-08-12
GB2375771A (en) 2002-11-27

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