ATE424842T1 - Proteine der bcl-2-familie und fragmente davon, und ihre verwendung bei krebspatienten - Google Patents
Proteine der bcl-2-familie und fragmente davon, und ihre verwendung bei krebspatientenInfo
- Publication number
- ATE424842T1 ATE424842T1 AT04797460T AT04797460T ATE424842T1 AT E424842 T1 ATE424842 T1 AT E424842T1 AT 04797460 T AT04797460 T AT 04797460T AT 04797460 T AT04797460 T AT 04797460T AT E424842 T1 ATE424842 T1 AT E424842T1
- Authority
- AT
- Austria
- Prior art keywords
- fragments
- bcl
- cancer patients
- family proteins
- proteins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52311903P | 2003-11-19 | 2003-11-19 | |
| DKPA200301716 | 2003-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424842T1 true ATE424842T1 (de) | 2009-03-15 |
Family
ID=39149116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04797460T ATE424842T1 (de) | 2003-11-19 | 2004-11-18 | Proteine der bcl-2-familie und fragmente davon, und ihre verwendung bei krebspatienten |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7842294B2 (de) |
| EP (2) | EP1691824B1 (de) |
| JP (2) | JP4926714B2 (de) |
| KR (2) | KR101284237B1 (de) |
| CN (1) | CN1921878B (de) |
| AT (1) | ATE424842T1 (de) |
| AU (1) | AU2004290866B2 (de) |
| CA (1) | CA2546794C (de) |
| DE (1) | DE602004019965D1 (de) |
| DK (2) | DK1691824T3 (de) |
| ES (2) | ES2436429T3 (de) |
| MX (1) | MXPA06005738A (de) |
| PL (2) | PL2087904T3 (de) |
| PT (1) | PT1691824E (de) |
| RU (1) | RU2367468C2 (de) |
| WO (1) | WO2005049073A2 (de) |
| ZA (1) | ZA200604866B (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7892559B2 (en) * | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
| ES2633389T3 (es) * | 2003-01-30 | 2017-09-21 | Survac Aps | Péptidos derivados de survivina y uso de los mismos |
| WO2006034334A2 (en) | 2004-09-21 | 2006-03-30 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Peptide analogs capable of enhancing stimulation of a glioma-specific ctl response |
| JP2008517070A (ja) * | 2004-10-19 | 2008-05-22 | マサチューセッツ インスティテュート オブ テクノロジー | 自己組織化式の可撓性かつ軽量のリチウム電池のためのウイルス骨格 |
| AU2011203535B2 (en) * | 2005-02-04 | 2012-10-11 | Survac Aps | Survivin peptide vaccine |
| CN103143004A (zh) * | 2005-02-04 | 2013-06-12 | 萨瓦克公司 | 存活蛋白肽疫苗 |
| US20100317577A1 (en) * | 2005-09-09 | 2010-12-16 | Department Of Health And Human Services | Methods and Compositions for Inhibiting Cell Death or Enhacing Cell Proliferation |
| EP2361930A3 (de) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimere von peptide-mhc komplexen und deren verwendung in borrelia infektionskrankheiten |
| EP3620465B1 (de) * | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| EP2254592B1 (de) * | 2008-02-28 | 2019-06-05 | Dako Denmark A/S | Mhc-multimere in borrelia-diagnostika und erkrankungen |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| EP2285832B1 (de) | 2008-05-16 | 2020-08-26 | Taiga Biotechnologies, Inc. | Antikörper und herstellungsverfahren dafür |
| WO2010009350A2 (en) * | 2008-07-16 | 2010-01-21 | Burnham Institute For Medical Research | Compositions and methods for modulating nod-like receptor activity and uses thereof |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| EP2318435B1 (de) | 2008-08-28 | 2015-12-23 | Taiga Biotechnologies, Inc. | Myc-modulatoren, verfahren zu ihrer verwendung und verfahren zur identifikation von mitteln zur myc-modulierung |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| WO2010037395A2 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| WO2010037397A1 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cmv immune monitoring |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| WO2010045573A2 (en) * | 2008-10-17 | 2010-04-22 | University Of Miami | Tumor vaccine |
| EP3444333A1 (de) * | 2009-10-22 | 2019-02-20 | Thomas Jefferson University | Zellbasierte antikrebszusammensetzungen sowie verfahren zur herstellung und verwendung davon |
| WO2011111392A1 (en) * | 2010-03-11 | 2011-09-15 | Oncotherapy Science, Inc. | Hjurp peptides and vaccines including the same |
| EP2608799B1 (de) * | 2010-08-24 | 2018-12-12 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Impfstoffe gegen hirntumore auf interleukin-13-rezeptor-alpha 2-peptid-basis |
| DK3536334T3 (da) | 2012-05-16 | 2021-09-13 | Stemline Therapeutics Inc | Cancer stamcelle målrettede cancer vacciner |
| JP6285930B2 (ja) * | 2012-07-20 | 2018-02-28 | タイガ バイオテクノロジーズ,インク. | 造血コンパートメントの再構築及び自家再構築の増進 |
| CN105228640B (zh) * | 2013-02-26 | 2018-01-16 | 王荣福 | Phf20和jmjd3组合物及其在肿瘤免疫治疗中的使用方法 |
| RU2671897C2 (ru) * | 2013-03-01 | 2018-11-07 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Способы получения из опухоли обогащенных популяций реактивных в отношении опухоли т-клеток |
| US9704181B2 (en) * | 2014-05-06 | 2017-07-11 | International Business Machines Corporation | Real-time social group based bidding system |
| KR20190092472A (ko) | 2016-12-02 | 2019-08-07 | 타이가 바이오테크놀로지스, 인코포레이티드 | 나노입자 제제 |
| MA47367B1 (fr) * | 2017-01-27 | 2023-06-28 | Immatics Biotechnologies Gmbh | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers |
| IL299051A (en) * | 2017-01-27 | 2023-02-01 | Immatics Biotechnologies Gmbh | New peptides and their combinations for immunotherapy against ovarian cancer and other cancers |
| EA201991444A1 (ru) | 2017-01-27 | 2019-12-30 | Имматикс Байотекнолоджиз Гмбх | Новые пептиды и комбинации пептидов для применения в иммунотерапии рака яичника и других видов рака |
| KR20210086612A (ko) | 2018-09-04 | 2021-07-08 | 트레오스 바이오 리미티드 | 펩타이드 백신 |
| US12258373B2 (en) | 2018-12-17 | 2025-03-25 | Immudex Aps | Panel comprising Borrelia MHC multimers |
| WO2020210231A1 (en) | 2019-04-08 | 2020-10-15 | Taiga Biotechnologies, Inc. | Compositions and methods for the cry opreservation of immune cells |
| EP3969041A4 (de) | 2019-05-14 | 2023-05-10 | Taiga Biotechnologies, Inc. | Zusammensetzungen und verfahren zur behandlung von t-zell-erschöpfung |
| CN113355432A (zh) * | 2021-05-12 | 2021-09-07 | 甘肃农业大学 | Bmf作为细胞凋亡标志物的应用 |
| WO2022245249A1 (ru) * | 2021-05-17 | 2022-11-24 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Пептидные соединения для индукции апоптоза в опухолевой клетке |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US5342774A (en) | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
| ES2225824T3 (es) | 1992-08-31 | 2005-03-16 | Ludwig Institute For Cancer Research | Nonapeptido aislado derivado del gen mage-3 y presentado por hla-a1, y sus usos. |
| US5470955A (en) | 1993-02-02 | 1995-11-28 | Dartmouth College | Antibodies which specifically bind mcl-1 polypeptide |
| US5646008A (en) * | 1993-06-22 | 1997-07-08 | The Regent Of The University Of Michigan | Vertebrate apoptosis gene: compositions and methods |
| US5700638A (en) * | 1993-08-26 | 1997-12-23 | Washington University | Cell death regulator |
| GB9320597D0 (en) | 1993-10-06 | 1993-11-24 | Proteus Molecular Design | Improvements in and realting to vaccines |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5789201A (en) * | 1996-02-23 | 1998-08-04 | Cocensys, Inc. | Genes coding for bcl-y a bcl-2 homologue |
| US6245523B1 (en) | 1996-11-20 | 2001-06-12 | Yale University | Survivin, a protein that inhibits cellular apoptosis, and its modulation |
| WO1998058541A1 (en) * | 1997-06-24 | 1998-12-30 | Dana-Farber Cancer Institute, Inc. | Modulation of apoptosis |
| AU3471200A (en) | 1999-11-16 | 2001-05-30 | Dartmouth College | Mcl-1 gene regulatory elements and a pro-apoptotic mcl-1 variant |
| CA2390662A1 (en) * | 1999-12-14 | 2001-06-21 | The Burnham Institute | Bcl-g polypeptides, encoding nucleic acids and methods of use |
| WO2002005835A2 (en) * | 2000-07-17 | 2002-01-24 | Washington University | Modulation of apoptosis |
| WO2002072627A2 (en) * | 2001-03-09 | 2002-09-19 | Callistogen Ag | Induction of anti-tumor cytotoxic t-lymphocytes in humans using peptide epitopes found by computer based algorithms for vaccination |
| US7892559B2 (en) * | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
| PL1618130T3 (pl) | 2003-04-11 | 2013-08-30 | Survac Aps | Szczepionka terapeutyczna przeciw nowotworom |
-
2004
- 2004-11-18 WO PCT/DK2004/000799 patent/WO2005049073A2/en not_active Ceased
- 2004-11-18 CN CN2004800407050A patent/CN1921878B/zh not_active Expired - Lifetime
- 2004-11-18 RU RU2006121466/15A patent/RU2367468C2/ru active
- 2004-11-18 DK DK04797460T patent/DK1691824T3/da active
- 2004-11-18 ZA ZA200604866A patent/ZA200604866B/en unknown
- 2004-11-18 EP EP04797460A patent/EP1691824B1/de not_active Expired - Lifetime
- 2004-11-18 CA CA2546794A patent/CA2546794C/en not_active Expired - Lifetime
- 2004-11-18 ES ES09154734.9T patent/ES2436429T3/es not_active Expired - Lifetime
- 2004-11-18 ES ES04797460T patent/ES2323588T3/es not_active Expired - Lifetime
- 2004-11-18 KR KR1020127016885A patent/KR101284237B1/ko not_active Expired - Lifetime
- 2004-11-18 AU AU2004290866A patent/AU2004290866B2/en not_active Expired
- 2004-11-18 PL PL09154734T patent/PL2087904T3/pl unknown
- 2004-11-18 KR KR1020067012186A patent/KR101216655B1/ko not_active Expired - Lifetime
- 2004-11-18 AT AT04797460T patent/ATE424842T1/de active
- 2004-11-18 PT PT04797460T patent/PT1691824E/pt unknown
- 2004-11-18 DK DK09154734.9T patent/DK2087904T3/da active
- 2004-11-18 MX MXPA06005738A patent/MXPA06005738A/es active IP Right Grant
- 2004-11-18 JP JP2006540170A patent/JP4926714B2/ja not_active Expired - Lifetime
- 2004-11-18 DE DE602004019965T patent/DE602004019965D1/de not_active Expired - Lifetime
- 2004-11-18 PL PL04797460T patent/PL1691824T3/pl unknown
- 2004-11-18 EP EP09154734.9A patent/EP2087904B1/de not_active Expired - Lifetime
- 2004-11-18 US US10/580,016 patent/US7842294B2/en active Active
-
2011
- 2011-09-12 JP JP2011198605A patent/JP5502823B2/ja not_active Expired - Lifetime
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