ATE425247T1 - Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen - Google Patents

Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen

Info

Publication number
ATE425247T1
ATE425247T1 AT03702506T AT03702506T ATE425247T1 AT E425247 T1 ATE425247 T1 AT E425247T1 AT 03702506 T AT03702506 T AT 03702506T AT 03702506 T AT03702506 T AT 03702506T AT E425247 T1 ATE425247 T1 AT E425247T1
Authority
AT
Austria
Prior art keywords
metastasis
cancer invasion
therapeutic use
preventive
synthetic peptides
Prior art date
Application number
AT03702506T
Other languages
English (en)
Inventor
Matthias Rath
Shrirang Netke
Aleksandra Niedzwiecki
Original Assignee
Matthias Rath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath filed Critical Matthias Rath
Application granted granted Critical
Publication of ATE425247T1 publication Critical patent/ATE425247T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03702506T 2002-01-23 2003-01-23 Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen ATE425247T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35131702P 2002-01-23 2002-01-23

Publications (1)

Publication Number Publication Date
ATE425247T1 true ATE425247T1 (de) 2009-03-15

Family

ID=27613485

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03702506T ATE425247T1 (de) 2002-01-23 2003-01-23 Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen

Country Status (22)

Country Link
US (1) US8012935B2 (de)
EP (1) EP1468085B1 (de)
JP (1) JP2005515262A (de)
KR (1) KR20040077764A (de)
CN (2) CN1622992A (de)
AT (1) ATE425247T1 (de)
BR (1) BR0302819A (de)
CA (1) CA2472775A1 (de)
DE (1) DE60326539D1 (de)
EE (1) EE200400030A (de)
ES (1) ES2324027T3 (de)
HR (1) HRP20040732A2 (de)
IL (1) IL162714A0 (de)
LV (2) LV13289B (de)
MX (1) MXPA04007170A (de)
NO (1) NO20034146L (de)
NZ (1) NZ533738A (de)
PL (1) PL209827B1 (de)
RU (1) RU2346043C2 (de)
WO (1) WO2003062413A1 (de)
YU (1) YU76403A (de)
ZA (1) ZA200405328B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856598B1 (fr) * 2003-06-25 2005-10-28 Inst Nat Sante Rech Med Peptides derives de la proteine mmp-2 et leur utilisation en immunotherapie antitumorale
JP4911950B2 (ja) * 2005-11-07 2012-04-04 晃 伊東 Mmp−1の部分ペプチドを用いた癌浸潤・転移阻害薬
CA2754635C (en) * 2009-03-06 2018-06-19 Universite Paris Descartes Use of gingival fibroblast conditioned media to treat metastatic cancer
US8593732B1 (en) * 2010-01-23 2013-11-26 Lightsmyth Technologies, Inc. Partially metallized total internal reflection immersion grating
US8003110B1 (en) * 2011-01-24 2011-08-23 Matthias W. Rath Metalloproteinase oligopeptides and their therapeutic use
EP2649985A1 (de) * 2012-04-13 2013-10-16 Lipotec, S.A. Verbindungen zur Hemmung neuronaler Exozytose (III)
US20140017267A1 (en) * 2012-07-13 2014-01-16 Matthias W Rath Metalloproteinase oligopeptides and their therapeutic use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US5280106A (en) * 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
GB8817075D0 (en) * 1988-07-18 1988-08-24 Raychem Ltd Oscillation suppressor
US5646027A (en) * 1994-09-08 1997-07-08 Warner-Lambert Company Process for the production of gelatinase catalytic domain protein
RU2142958C1 (ru) * 1997-12-25 1999-12-20 Товарищество с ограниченной ответственностью "Верта" Пептид, обладающий иммуномодулирующей активностью, и препарат на его основе
JP2004508801A (ja) 1999-10-29 2004-03-25 カイロン ソチエタ ア レスポンサビリタ リミタータ ナイセリア抗原性ペプチド

Also Published As

Publication number Publication date
NO20034146D0 (no) 2003-09-17
ZA200405328B (en) 2006-03-29
CA2472775A1 (en) 2003-07-31
JP2005515262A (ja) 2005-05-26
US20030139345A1 (en) 2003-07-24
PL209827B1 (pl) 2011-10-31
NZ533738A (en) 2006-03-31
PL371254A1 (en) 2005-06-13
HRP20040732A2 (en) 2005-06-30
ES2324027T3 (es) 2009-07-29
LV13289B (en) 2005-11-20
NO20034146L (no) 2003-10-28
DE60326539D1 (de) 2009-04-23
IL162714A0 (en) 2005-11-20
RU2004125599A (ru) 2005-07-10
LV13419B (en) 2006-09-20
EE200400030A (et) 2004-04-15
RU2346043C2 (ru) 2009-02-10
US8012935B2 (en) 2011-09-06
YU76403A (sh) 2006-05-25
KR20040077764A (ko) 2004-09-06
CN101007844A (zh) 2007-08-01
EP1468085B1 (de) 2009-03-11
EP1468085A1 (de) 2004-10-20
WO2003062413A1 (en) 2003-07-31
BR0302819A (pt) 2004-04-27
MXPA04007170A (es) 2004-10-29
CN1622992A (zh) 2005-06-01

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