ATE426020T1 - Lichtaktivierte gentransduktion unter verwendung von ultraviolettem licht zur zellengerichteten zufuhrung von genen - Google Patents

Lichtaktivierte gentransduktion unter verwendung von ultraviolettem licht zur zellengerichteten zufuhrung von genen

Info

Publication number
ATE426020T1
ATE426020T1 AT06124972T AT06124972T ATE426020T1 AT E426020 T1 ATE426020 T1 AT E426020T1 AT 06124972 T AT06124972 T AT 06124972T AT 06124972 T AT06124972 T AT 06124972T AT E426020 T1 ATE426020 T1 AT E426020T1
Authority
AT
Austria
Prior art keywords
cell
light
ultraviolet light
vector
genes
Prior art date
Application number
AT06124972T
Other languages
English (en)
Inventor
Edward M Schwarz
Thomas Foster
Regis J O'keefe
Jarod C Finlay
Original Assignee
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rochester filed Critical Univ Rochester
Application granted granted Critical
Publication of ATE426020T1 publication Critical patent/ATE426020T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT06124972T 2002-01-31 2003-01-31 Lichtaktivierte gentransduktion unter verwendung von ultraviolettem licht zur zellengerichteten zufuhrung von genen ATE426020T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35390702P 2002-01-31 2002-01-31
US35384202P 2002-01-31 2002-01-31

Publications (1)

Publication Number Publication Date
ATE426020T1 true ATE426020T1 (de) 2009-04-15

Family

ID=27669127

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03735128T ATE348884T1 (de) 2002-01-31 2003-01-31 Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung
AT06124972T ATE426020T1 (de) 2002-01-31 2003-01-31 Lichtaktivierte gentransduktion unter verwendung von ultraviolettem licht zur zellengerichteten zufuhrung von genen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03735128T ATE348884T1 (de) 2002-01-31 2003-01-31 Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung

Country Status (7)

Country Link
US (2) US7524327B2 (de)
EP (3) EP1472348B1 (de)
AT (2) ATE348884T1 (de)
AU (1) AU2003210820B2 (de)
CA (1) CA2474485A1 (de)
DE (2) DE60310525T2 (de)
WO (1) WO2003064680A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7704272B2 (en) * 2002-01-31 2010-04-27 University Of Rochester Method for introducing an ultraviolet light activated viral vector into the spinal column
AU2003210820B2 (en) * 2002-01-31 2007-12-20 University Of Rochester Light activated gene transduction using ultraviolet light for cell targeted gene delivery
US20040264853A1 (en) * 2003-01-31 2004-12-30 Schwarz Edward M Light probe for ultraviolet light activated gene transduction
WO2006024038A2 (en) * 2004-08-27 2006-03-02 Codman & Shurtleff Light-based implant for treating alzheimer’s disease
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
USRE47266E1 (en) * 2005-03-14 2019-03-05 DePuy Synthes Products, Inc. Light-based implants for treating Alzheimer's disease
US7288108B2 (en) 2005-03-14 2007-10-30 Codman & Shurtleff, Inc. Red light implant for treating Parkinson's disease
US8463439B2 (en) 2009-03-31 2013-06-11 Intuitive Surgical Operations, Inc. Optic fiber connection for a force sensing instrument
US7351253B2 (en) 2005-06-16 2008-04-01 Codman & Shurtleff, Inc. Intranasal red light probe for treating Alzheimer's disease
US7819907B2 (en) * 2005-10-31 2010-10-26 Codman & Shurtleff, Inc. Device and method for fixing adjacent bone plates
JP4761224B2 (ja) * 2006-10-12 2011-08-31 富士電機デバイステクノロジー株式会社 垂直磁気記録媒体
US9320914B2 (en) 2008-03-03 2016-04-26 DePuy Synthes Products, Inc. Endoscopic delivery of red/NIR light to the subventricular zone

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AT395321B (de) * 1983-07-05 1992-11-25 Ebner Ind Ofenbau Verfahren zum abkuehlen von chargen in diskontinuierlich arbeitenden industrieoefen, insbesondere von stahldraht- oder - bandbunden in haubengluehoefen
CA1245726A (en) 1984-01-19 1988-11-29 Francis A. L'esperance Laser incisional device
US4671273A (en) 1984-03-19 1987-06-09 Lindsey Ernest J Laser hand piece, for use in opthalmic, plastic, and ear, nose, and throat surgery
DE3415293C2 (de) 1984-04-24 1987-02-12 Osada Electric Co. Ltd., Tokio/Tokyo Laser-Handgerät
US5188632A (en) * 1984-12-07 1993-02-23 Advanced Interventional Systems, Inc. Guidance and delivery system for high-energy pulsed laser light
US4846172A (en) * 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
WO1989003202A2 (en) 1987-10-14 1989-04-20 Schneider Richard T Method and apparatus for laser emulsification
US5084043A (en) * 1990-01-12 1992-01-28 Laserscope Method for performing a percutaneous diskectomy using a laser
US5201729A (en) * 1990-01-12 1993-04-13 Laserscope Method for performing percutaneous diskectomy using a laser
US5242439A (en) * 1990-01-12 1993-09-07 Laserscope Means for inserting instrumentation for a percutaneous diskectomy using a laser
DE4219626A1 (de) 1992-06-16 1993-12-23 Wehling Peter Priv Doz Dr Med Methode zur Einschleusung therapeutisch relevanter Gene in Körperzellen
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
HK1004920A1 (en) 1993-01-21 1998-12-11 President And Fellows Of Harvard College Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound
DE9317847U1 (de) 1993-10-29 1994-01-20 Elkady, Hesham, Dr., 21682 Stade Kanüle
US5604090A (en) * 1994-06-06 1997-02-18 Fred Hutchinson Cancer Research Center Method for increasing transduction of cells by adeno-associated virus vectors
IL115851A0 (en) * 1995-11-02 1996-01-31 Riklis Emanual Cosmetic compositions
US5883740A (en) * 1995-12-14 1999-03-16 Chubb; Charles R. Skin light exposure control methods
US5843459A (en) * 1996-01-19 1998-12-01 Human Gene Therapy Research Institute Differential inactivation of nucleic acids by chemical modification
ES2320603T3 (es) * 1997-07-30 2009-05-25 Emory University Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
DE29716011U1 (de) 1997-09-06 1997-10-30 Reitenbach, Paul, 48165 Münster Gerät zur ultravioletten intravenösen Bestrahlung des Eigenblutes mit fieberoptischer Lichtsonde
AU3189899A (en) 1998-03-18 1999-10-11 University Of Virginia Patent Foundation Gene therapy vector with osteocalcin promoter and genes for bone morphogenic proteins or growth factors
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EP1349865A2 (de) * 2000-12-15 2003-10-08 Mitokor Cobalt-porphyrin komplexe und deren verwendung als mittel zur bekämpfung von fettleibigkeit
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ATE350010T1 (de) * 2001-02-23 2007-01-15 Richter Chem Lab Zusammensetzung zur topischen anwendung
AU2003210820B2 (en) * 2002-01-31 2007-12-20 University Of Rochester Light activated gene transduction using ultraviolet light for cell targeted gene delivery
US7704272B2 (en) * 2002-01-31 2010-04-27 University Of Rochester Method for introducing an ultraviolet light activated viral vector into the spinal column
US20040264853A1 (en) * 2003-01-31 2004-12-30 Schwarz Edward M Light probe for ultraviolet light activated gene transduction

Also Published As

Publication number Publication date
EP1472348B1 (de) 2006-12-20
EP1867715B1 (de) 2009-03-18
WO2003064680A3 (en) 2004-07-22
WO2003064680A2 (en) 2003-08-07
EP1939285A1 (de) 2008-07-02
CA2474485A1 (en) 2003-08-07
DE60326781D1 (de) 2009-04-30
US7524327B2 (en) 2009-04-28
ATE348884T1 (de) 2007-01-15
DE60310525T2 (de) 2007-10-04
US20090093867A1 (en) 2009-04-09
AU2003210820B2 (en) 2007-12-20
EP1472348A2 (de) 2004-11-03
EP1867715A1 (de) 2007-12-19
US20030236394A1 (en) 2003-12-25
EP1472348A4 (de) 2005-04-13
DE60310525D1 (de) 2007-02-01

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