ATE426025T1 - Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose - Google Patents

Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose

Info

Publication number
ATE426025T1
ATE426025T1 AT03005931T AT03005931T ATE426025T1 AT E426025 T1 ATE426025 T1 AT E426025T1 AT 03005931 T AT03005931 T AT 03005931T AT 03005931 T AT03005931 T AT 03005931T AT E426025 T1 ATE426025 T1 AT E426025T1
Authority
AT
Austria
Prior art keywords
tuberculosis
compounds
diagnosis
methods
immunotherapy
Prior art date
Application number
AT03005931T
Other languages
English (en)
Inventor
Steven G Reed
Yasir A W Skeiky
Antonio Campos-Neto
Raymond L Houghton
Thomas S Vedvick
Daniel R Twardzik
Davin C Dillon
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE426025(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of ATE426025T1 publication Critical patent/ATE426025T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03005931T 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose ATE426025T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52343695A 1995-09-01 1995-09-01
US53363495A 1995-09-22 1995-09-22
US62087496A 1996-03-22 1996-03-22
US65968396A 1996-06-05 1996-06-05
US68057496A 1996-07-12 1996-07-12

Publications (1)

Publication Number Publication Date
ATE426025T1 true ATE426025T1 (de) 2009-04-15

Family

ID=27541835

Family Applications (5)

Application Number Title Priority Date Filing Date
AT96933009T ATE252640T1 (de) 1995-09-01 1996-08-30 Verbindungen zur immunotherapie und diagnose von tuberkulose
AT03021501T ATE337399T1 (de) 1995-09-01 1996-08-30 Zusammensetzungen zur immuntherapie und diagnose von tuberculosis
AT03005931T ATE426025T1 (de) 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose
AT06112509T ATE513915T1 (de) 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose
AT01126628T ATE323165T1 (de) 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT96933009T ATE252640T1 (de) 1995-09-01 1996-08-30 Verbindungen zur immunotherapie und diagnose von tuberkulose
AT03021501T ATE337399T1 (de) 1995-09-01 1996-08-30 Zusammensetzungen zur immuntherapie und diagnose von tuberculosis

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT06112509T ATE513915T1 (de) 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose
AT01126628T ATE323165T1 (de) 1995-09-01 1996-08-30 Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose

Country Status (23)

Country Link
EP (5) EP1203817B9 (de)
JP (5) JP4382160B2 (de)
KR (1) KR100433750B1 (de)
CN (1) CN1117149C (de)
AT (5) ATE252640T1 (de)
AU (1) AU727602B2 (de)
BR (2) BR9610262B1 (de)
CA (3) CA2230885C (de)
CY (2) CY2570B1 (de)
CZ (3) CZ300688B6 (de)
DE (4) DE69637879D1 (de)
DK (4) DK0851927T3 (de)
ES (4) ES2324529T3 (de)
HU (2) HU227778B1 (de)
IL (1) IL123506A (de)
MX (1) MX9801638A (de)
NO (4) NO324372B1 (de)
NZ (1) NZ319377A (de)
PL (1) PL186774B1 (de)
PT (4) PT1347055E (de)
SI (1) SI0851927T1 (de)
TR (5) TR199800411T1 (de)
WO (1) WO1997009428A2 (de)

Families Citing this family (45)

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JP2501135Y2 (ja) 1989-06-10 1996-06-12 エヌティエヌ株式会社 摩擦式無段変速機
JP2501911B2 (ja) 1989-08-15 1996-05-29 日産自動車株式会社 トロイダル型無段変速機
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
CA2268036A1 (en) * 1996-10-11 1998-04-23 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6544522B1 (en) * 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
JP4172598B2 (ja) * 1997-04-02 2008-10-29 スタテンス セールム インスティトゥート 結核菌由来の核酸フラグメント及びポリペプチドフラグメント
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6555653B2 (en) * 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
WO1999004005A1 (en) * 1997-07-16 1999-01-28 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
EP1484405A1 (de) * 1997-11-10 2004-12-08 Statens Serum Institut Nukleinsäure- und polypeptidfragmente von M. Tuberculosis
WO1999024577A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)
BR9909472A (pt) 1998-04-07 2001-09-11 Corixa Corp Polipeptìdeo purificado, processo para prevenir tuberculose, e, composição farmacêutica
GB9808720D0 (en) * 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
DE69941545D1 (de) * 1998-11-04 2009-11-26 Isis Innovation Tuberkulose diagnose test
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
AU2594500A (en) * 1998-12-24 2000-07-31 Corixa Corporation Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
WO2000066157A1 (en) 1999-05-04 2000-11-09 The Public Health Research Institute Of The City Of New York, Inc. Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines
US7009042B1 (en) * 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
WO2001062893A2 (en) 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
PT2133100E (pt) 2000-06-20 2012-01-11 Corixa Corp Antigénio mtb32a de mycobacterium tuberculosis com um local activo inactivado e suas proteínas de fusão
AU2003213118A1 (en) 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
ITRM20040091A1 (it) 2004-02-19 2004-05-19 Istituto Naz Per Le Malattie Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
FI119445B (fi) * 2004-10-29 2008-11-14 Waertsilae Finland Oy Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin
BRPI0518933A2 (pt) 2004-11-16 2008-12-16 Crucell Holland B V E Aeras Gl adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium
PT2426141E (pt) 2005-04-29 2014-11-25 Glaxosmithkline Biolog Sa Método para prevenção ou tratamento de uma infecção por m. tuberculosis
FR2952058B1 (fr) 2009-10-29 2013-10-04 Centre Nat Rech Scient Procede de ligation native de polypeptides
LT2528621T (lt) 2010-01-27 2016-12-12 Glaxosmithkline Biologicals S.A. Modifikuoti tuberkuliozės antigenai
SG190937A1 (en) 2010-12-14 2013-07-31 Glaxosmithkline Biolog Sa Mycobacterium antigenic composition
FR2971509B1 (fr) * 2011-02-16 2013-02-22 Centre Nat Rech Scient Procede de preparation de peptides par assemblage de multiples fragments peptidiques
CN103290030A (zh) * 2012-02-23 2013-09-11 上海交通大学 一种结核分枝杆菌标志物HtdY的重组蛋白及其制备方法和临床应用
PL2844282T3 (pl) * 2012-05-04 2019-11-29 Pfizer Antygeny związane z gruczołem krokowym i schematy immunoterapii oparte na szczepionce
CN111233992B (zh) * 2014-04-04 2024-07-19 韦斯塔隆公司 人工活化的肽
GB201513176D0 (en) 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
FR3048286B1 (fr) * 2016-02-26 2021-01-22 Omunis Peptides immunogenes et leur utilisation
CN107304231B (zh) * 2016-04-18 2021-01-01 华中农业大学 一种结核分枝杆菌融合蛋白及应用
GB201614485D0 (en) * 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition

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FR2244539A1 (en) * 1973-07-13 1975-04-18 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
FR2265402A1 (en) * 1974-03-29 1975-10-24 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
US4876089A (en) * 1984-09-06 1989-10-24 Chiron Corporation Feline leukemia virus protein vaccines
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
FR2677365B1 (fr) * 1991-06-07 1995-08-04 Pasteur Institut Proteines de mycobacterium et applications.
US5330754A (en) * 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
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Also Published As

Publication number Publication date
EP0851927B1 (de) 2003-10-22
WO1997009428A3 (en) 1997-07-17
NZ319377A (en) 2000-01-28
ES2324529T3 (es) 2009-08-10
EP1347055A2 (de) 2003-09-24
TR200901109T1 (tr) 2012-02-21
BR9610262A (pt) 1999-07-06
NO336288B1 (no) 2015-07-13
NO20070618L (no) 1998-04-27
HK1059282A1 (en) 2004-06-25
ATE513915T1 (de) 2011-07-15
DE69636487D1 (de) 2006-10-05
IL123506A0 (en) 1998-10-30
EP1712628B1 (de) 2011-06-22
CY2612B2 (en) 2010-12-22
TR200806259T2 (tr) 2008-10-21
EP1203817A3 (de) 2003-01-29
IL123506A (en) 2004-12-15
EP1203817B1 (de) 2006-04-12
CY2570B1 (en) 2008-07-02
HUP9900902A3 (en) 2001-03-28
HU227778B1 (en) 2012-02-28
DE69630457T2 (de) 2004-11-25
EP1398379A2 (de) 2004-03-17
EP1347055A3 (de) 2003-11-26
CZ300953B6 (cs) 2009-09-23
TR199800411T1 (xx) 1998-05-21
CN1200147A (zh) 1998-11-25
NO980883D0 (no) 1998-02-27
DE69636487T2 (de) 2007-05-03
NO20070621L (no) 1998-04-27
CA2653566A1 (en) 1997-03-13
JP4324596B2 (ja) 2009-09-02
AU7158696A (en) 1997-03-27
DK1398379T3 (da) 2007-01-08
DE69636046T2 (de) 2006-11-23
ATE252640T1 (de) 2003-11-15
TR200403064T2 (tr) 2005-08-22
JP4382160B2 (ja) 2009-12-09
JP2007228972A (ja) 2007-09-13
PT851927E (pt) 2004-03-31
DK0851927T3 (da) 2004-01-26
EP1398379A3 (de) 2004-07-14
PT1398379E (pt) 2007-01-31
ES2271449T3 (es) 2007-04-16
ES2262595T3 (es) 2006-12-01
PT1203817E (pt) 2006-08-31
WO1997009428A2 (en) 1997-03-13
ES2210392T3 (es) 2004-07-01
EP1203817A2 (de) 2002-05-08
JP2009159982A (ja) 2009-07-23
EP1347055B1 (de) 2009-03-18
EP1398379B1 (de) 2006-08-23
PT1347055E (pt) 2009-06-19
CZ62898A3 (cs) 1999-10-13
TR200806258T2 (tr) 2008-10-21
CZ300688B6 (cs) 2009-07-15
JP2006149406A (ja) 2006-06-15
ATE337399T1 (de) 2006-09-15
BR9612997B1 (pt) 2012-01-10
JP4324618B2 (ja) 2009-09-02
BR9610262B1 (pt) 2013-11-26
EP1203817B9 (de) 2006-08-16
EP1712628A2 (de) 2006-10-18
DK1347055T3 (da) 2009-06-29
PL325373A1 (en) 1998-07-20
DE69636046D1 (de) 2006-05-24
MX9801638A (es) 1998-05-31
ATE323165T1 (de) 2006-04-15
SI0851927T1 (en) 2004-02-29
CA2653566C (en) 2013-06-25
NO980883L (no) 1998-04-27
CA2684425A1 (en) 1997-03-13
NO20070619L (no) 1998-04-27
NO324372B1 (no) 2007-10-01
KR19990044347A (ko) 1999-06-25
CZ297406B6 (cs) 2006-12-13
JP4324597B2 (ja) 2009-09-02
CA2230885C (en) 2010-02-02
JP2001517069A (ja) 2001-10-02
HU225979B1 (en) 2008-02-28
AU727602B2 (en) 2000-12-14
PL186774B1 (pl) 2004-02-27
KR100433750B1 (ko) 2004-09-01
CN1117149C (zh) 2003-08-06
DE69637879D1 (de) 2009-04-30
DE69630457D1 (de) 2003-11-27
CA2230885A1 (en) 1997-03-13
DK1203817T3 (da) 2006-08-14
EP0851927A2 (de) 1998-07-08
HUP9900902A2 (hu) 1999-07-28
JP2006187292A (ja) 2006-07-20
EP1712628A3 (de) 2007-05-23

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