ATE426410T1 - Behandlung der oralen und darm mukositis durch verabreichung von menschlichem il-18 - Google Patents

Behandlung der oralen und darm mukositis durch verabreichung von menschlichem il-18

Info

Publication number
ATE426410T1
ATE426410T1 AT05789011T AT05789011T ATE426410T1 AT E426410 T1 ATE426410 T1 AT E426410T1 AT 05789011 T AT05789011 T AT 05789011T AT 05789011 T AT05789011 T AT 05789011T AT E426410 T1 ATE426410 T1 AT E426410T1
Authority
AT
Austria
Prior art keywords
human
treatment
oral
administration
intestinal mucositis
Prior art date
Application number
AT05789011T
Other languages
English (en)
Inventor
Judithann Lee
Kimberly Dede
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE426410T1 publication Critical patent/ATE426410T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05789011T 2004-08-20 2005-08-18 Behandlung der oralen und darm mukositis durch verabreichung von menschlichem il-18 ATE426410T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60301204P 2004-08-20 2004-08-20

Publications (1)

Publication Number Publication Date
ATE426410T1 true ATE426410T1 (de) 2009-04-15

Family

ID=35968167

Family Applications (2)

Application Number Title Priority Date Filing Date
AT09155870T ATE526057T1 (de) 2004-08-20 2005-08-18 Wundheilung durch verabreichung von menschlichem il-18
AT05789011T ATE426410T1 (de) 2004-08-20 2005-08-18 Behandlung der oralen und darm mukositis durch verabreichung von menschlichem il-18

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT09155870T ATE526057T1 (de) 2004-08-20 2005-08-18 Wundheilung durch verabreichung von menschlichem il-18

Country Status (23)

Country Link
US (1) US7595039B2 (de)
EP (2) EP2161032B1 (de)
JP (1) JP4912306B2 (de)
KR (1) KR20070050924A (de)
CN (1) CN101039696B (de)
AT (2) ATE526057T1 (de)
AU (1) AU2005277404A1 (de)
BR (1) BRPI0514445A (de)
CA (1) CA2577777A1 (de)
CY (1) CY1108991T1 (de)
DE (1) DE602005013542D1 (de)
DK (1) DK1793859T3 (de)
ES (2) ES2372728T3 (de)
IL (1) IL181286A0 (de)
MX (1) MX2007002134A (de)
NO (1) NO20071238L (de)
NZ (1) NZ552837A (de)
PL (1) PL1793859T3 (de)
PT (1) PT1793859E (de)
RU (1) RU2387455C2 (de)
SI (1) SI1793859T1 (de)
WO (1) WO2006023623A2 (de)
ZA (1) ZA200700524B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK12942002A3 (sk) * 2000-02-10 2003-05-02 Abbott Laboratories Protilátky viažuce ľudský interleukín-18, spôsoby ich výroby a použitia
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
RU2423971C1 (ru) * 2010-06-01 2011-07-20 Закрытое акционерное общество "Биологические исследования и системы" Способ ускорения заживления кожных повреждений, вызванных денервацией и нарушением кровоснабжения
WO2012174056A1 (en) 2011-06-13 2012-12-20 Neumedicines, Inc. Mitigation of cutaneous injury with il-12
WO2015032932A1 (en) * 2013-09-05 2015-03-12 Ab2 Bio Sa Il-18 binding protein (il-18bp) in inflammatory diseases
CN107660150B (zh) 2015-03-05 2023-10-24 Ab2生物股份有限公司 Il-18结合蛋白(il-18bp)和抗体在炎性疾病中
JP7795181B2 (ja) 2017-09-06 2026-01-07 イェール ユニバーシティー インターロイキン－１８バリアントとその利用法
AU2023226512A1 (en) 2022-02-23 2024-08-29 Bright Peak Therapeutics Ag Immune antigen specific il-18 immunocytokines and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69519454T2 (de) 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP4004088B2 (ja) 1995-09-26 2007-11-07 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
TW581771B (en) 1994-11-15 2004-04-01 Hayashibara Biochem Lab Recombinant production of a polypeptide for inducing interferon-gamma production, and monoclonal antibody against the polypeptide
US5680795A (en) 1995-07-05 1997-10-28 Norco Inc. Mechanical drive assembly incorporating counter-spring biassed radially-adjustable rollers
JP4024366B2 (ja) * 1996-11-29 2007-12-19 株式会社林原生物化学研究所 ポリペプチド
AU6636098A (en) * 1998-03-07 1999-09-20 Dae Woong Pharmaceutical Co., Ltd. Topical composition containing human epidermal growth factor
TWI227136B (en) * 1998-05-21 2005-02-01 Smithkline Beecham Corp Novel pharmaceutical composition for the prevention and/or treatment of cancer
AU2001275166B2 (en) * 2000-06-02 2005-07-28 Smithkline Beecham Corporation Methods of treating viral diseases with il-18 and il-18 combinations
PL208592B1 (pl) * 2000-06-15 2011-05-31 Smithkline Beecham Corp Sposób wytwarzania aktywnego ludzkiego polipeptydu IL-18 z ludzkiego polipeptydu prekursora IL-18
JP4381138B2 (ja) * 2001-07-12 2009-12-09 大鵬薬品工業株式会社 Ｉｌ−１８遺伝子導入動物
DK2298338T3 (da) * 2002-09-16 2012-09-24 Agennix Inc Lactoferrin-sammensætninger og fremgangsmåder til behandling af hudsår
AU2003295331A1 (en) * 2002-09-19 2004-04-23 Centocor, Inc. Method of inducing maturation of dendritic cells and uses therefor
US20050075277A1 (en) * 2003-07-10 2005-04-07 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects

Also Published As

Publication number Publication date
US7595039B2 (en) 2009-09-29
NO20071238L (no) 2007-05-14
PL1793859T3 (pl) 2009-08-31
RU2387455C2 (ru) 2010-04-27
MX2007002134A (es) 2007-09-14
NZ552837A (en) 2009-09-25
SI1793859T1 (sl) 2009-06-30
WO2006023623A3 (en) 2006-08-24
EP1793859A4 (de) 2008-02-13
DE602005013542D1 (de) 2009-05-07
DK1793859T3 (da) 2009-06-22
IL181286A0 (en) 2007-07-04
RU2007110166A (ru) 2008-09-27
AU2005277404A1 (en) 2006-03-02
CA2577777A1 (en) 2006-03-02
ES2372728T3 (es) 2012-01-25
US20060039892A1 (en) 2006-02-23
PT1793859E (pt) 2009-06-04
ATE526057T1 (de) 2011-10-15
JP2008510709A (ja) 2008-04-10
EP2161032B1 (de) 2011-09-28
EP2161032A3 (de) 2010-07-28
BRPI0514445A (pt) 2008-06-10
CN101039696A (zh) 2007-09-19
ES2322605T3 (es) 2009-06-23
KR20070050924A (ko) 2007-05-16
EP1793859B1 (de) 2009-03-25
ZA200700524B (en) 2008-05-28
JP4912306B2 (ja) 2012-04-11
EP1793859A2 (de) 2007-06-13
EP2161032A2 (de) 2010-03-10
HK1109054A1 (en) 2008-05-30
CY1108991T1 (el) 2014-07-02
WO2006023623A2 (en) 2006-03-02
CN101039696B (zh) 2011-08-17

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