ATE426671T1 - Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli - Google Patents

Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli

Info

Publication number
ATE426671T1
ATE426671T1 AT03723103T AT03723103T ATE426671T1 AT E426671 T1 ATE426671 T1 AT E426671T1 AT 03723103 T AT03723103 T AT 03723103T AT 03723103 T AT03723103 T AT 03723103T AT E426671 T1 ATE426671 T1 AT E426671T1
Authority
AT
Austria
Prior art keywords
escherichia coli
actinomycete
gene
expression system
ferredoxin
Prior art date
Application number
AT03723103T
Other languages
English (en)
Inventor
Akira Arisawa
Ayako Kumeda
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Application granted granted Critical
Publication of ATE426671T1 publication Critical patent/ATE426671T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0095—Oxidoreductases (1.) acting on iron-sulfur proteins as donor (1.18)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03723103T 2002-04-12 2003-04-11 Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli ATE426671T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002110311 2002-04-12

Publications (1)

Publication Number Publication Date
ATE426671T1 true ATE426671T1 (de) 2009-04-15

Family

ID=29243226

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03723103T ATE426671T1 (de) 2002-04-12 2003-04-11 Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli

Country Status (7)

Country Link
US (1) US20060234337A1 (de)
EP (1) EP1500704B1 (de)
JP (1) JP4251554B2 (de)
AT (1) ATE426671T1 (de)
AU (1) AU2003236095A1 (de)
DE (1) DE60326832D1 (de)
WO (1) WO2003087381A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2546614A1 (en) * 2003-11-27 2005-06-09 Mercian Corporation Dna participating in hydroxylation of macrolide compound
US8008049B2 (en) 2004-07-20 2011-08-30 Eisai R&D Management Co., Ltd. DNA coding for polypeptide participating in biosynthesis of pladienolide
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
TW200716744A (en) * 2005-05-26 2007-05-01 Eisai R&D Man Co Ltd Genetically modified microorganism and process for production of macrolide compound using the microorganism
JP4969448B2 (ja) * 2005-09-13 2012-07-04 日本マイクロバイオファーマ株式会社 シトクロムｐ４５０の生物学的変換反応系
CN101351551A (zh) * 2005-11-29 2009-01-21 协和发酵工业株式会社 新型蛋白质和编码该蛋白质的dna
KR100824541B1 (ko) 2007-02-26 2008-04-24 고려대학교 산학협력단 항산화 효소의 과발현을 통해 환경오염물질 분해능이향상된 균주
WO2008105513A1 (ja) 2007-03-01 2008-09-04 Mercian Corporation 多剤排出蛋白質欠損株由来の形質転換株およびそれらを用いた微生物変換方法
EP2130916B1 (de) * 2007-03-01 2015-09-02 MicroBiopharm Japan Co., Ltd. Zur expression von cytochrom p-450 fähige e. coli und biokonversionsverfahren unter verwendung davon
JP5550041B2 (ja) 2007-09-27 2014-07-16 塩野義製薬株式会社 チトクロームｐ４５０を用いたアダマンタン水酸化体の製造方法
WO2009113099A2 (en) * 2008-02-06 2009-09-17 Biocon Limited Fermentation medias and processes thereof
CN102272304B (zh) 2009-01-07 2013-10-23 三菱化学株式会社 切断固醇侧链的酶蛋白质及其应用
CN106139887A (zh) * 2015-05-13 2016-11-23 三星电子株式会社 包含编码具有羟化酶活性的蛋白质的基因的微生物和使用其降低样品中氟化甲烷浓度的方法
US10150080B2 (en) 2015-10-23 2018-12-11 Samsung Electronics Co., Ltd. Microorganism including gene encoding protein having dehalogenase activity and method of reducing concentration of fluorinated methane in sample using the same
US10358632B2 (en) 2015-12-07 2019-07-23 Samsung Electronics Co., Ltd. Bacterial cytochrome P450 protein variant and method of reducing concentration of fluorinated methane in sample using the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2672551B2 (ja) 1987-03-02 1997-11-05 三共株式会社 チトクロームｐ−４５０遺伝子を含有するｄｎａ
JPH07502650A (ja) 1991-12-16 1995-03-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー ストレプトミセスにおけるＰ４５０ｓｏｙおよびフェレドキシン−ｓｏｙの構成性発現、および組み換え体生物による化学物質の生物変換
JP2517894B2 (ja) 1994-08-12 1996-07-24 住友化学工業株式会社 フェレドキシン及びフェレドキシン還元酵素を同時に発現させるキメラｐ４５０産生菌株
FR2741620B1 (fr) * 1995-11-28 1997-12-26 Oreal Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
JP3353828B2 (ja) 1999-08-06 2002-12-03 富士ゼロックス株式会社 記録装置および記録方法
US6368781B1 (en) 1999-10-20 2002-04-09 Eastman Kodak Company Heat sensitivity improvement with combinations of gold sensitization and spectral sensitizing dye and filter device
US20030068788A1 (en) * 2001-05-16 2003-04-10 Buckel Thomas Gunther Methods and compositions for making emamectin
DK1270722T3 (da) * 2001-06-22 2007-05-14 Inst Francais Du Petrole Cytochrom P-450-klynge fra Rhodococcus ruber og anvendelse deraf til etherbrændstofspaltning
WO2003057830A2 (en) * 2001-12-26 2003-07-17 Bristol-Myers Squibb Company Compositions and methods for hydroxylating epothilones

Also Published As

Publication number Publication date
JPWO2003087381A1 (ja) 2005-08-18
AU2003236095A1 (en) 2003-10-27
EP1500704A1 (de) 2005-01-26
US20060234337A1 (en) 2006-10-19
WO2003087381A1 (en) 2003-10-23
JP4251554B2 (ja) 2009-04-08
EP1500704A4 (de) 2006-04-05
DE60326832D1 (de) 2009-05-07
EP1500704B1 (de) 2009-03-25

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