ATE427499T1 - Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen - Google Patents
Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinenInfo
- Publication number
- ATE427499T1 ATE427499T1 AT05751819T AT05751819T ATE427499T1 AT E427499 T1 ATE427499 T1 AT E427499T1 AT 05751819 T AT05751819 T AT 05751819T AT 05751819 T AT05751819 T AT 05751819T AT E427499 T1 ATE427499 T1 AT E427499T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- methods
- serum glycoproteins
- quantifying serum
- quantifying
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 3
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 102000004506 Blood Proteins Human genes 0.000 abstract 1
- 108010017384 Blood Proteins Proteins 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57359304P | 2004-05-21 | 2004-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE427499T1 true ATE427499T1 (de) | 2009-04-15 |
Family
ID=35429005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05751819T ATE427499T1 (de) | 2004-05-21 | 2005-05-20 | Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20060141528A1 (de) |
| EP (4) | EP1766412B1 (de) |
| AT (1) | ATE427499T1 (de) |
| DE (1) | DE602005013670D1 (de) |
| DK (1) | DK1766412T3 (de) |
| WO (1) | WO2005114221A2 (de) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60124265D1 (de) * | 2000-05-05 | 2006-12-14 | Purdue Research Foundation | Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen |
| EP1432992A2 (de) * | 2001-09-27 | 2004-06-30 | Purdue Research Foundation | Kontrolle von isotopeneffekten während der analytfraktionierung |
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| US7384754B2 (en) * | 2003-10-31 | 2008-06-10 | Agilent Technologies, Inc. | Enrichment and tagging of glycosylated proteins |
| DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| WO2007047796A2 (en) * | 2005-10-17 | 2007-04-26 | Institute For Systems Biology | Tissue-and serum-derived glycoproteins and methods of their use |
| EP1790664A1 (de) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs |
| CA2660286A1 (en) * | 2006-08-09 | 2008-02-21 | Homestead Clinical Corporation | Organ-specific proteins and methods of their use |
| US7879799B2 (en) * | 2006-08-10 | 2011-02-01 | Institute For Systems Biology | Methods for characterizing glycoproteins and generating antibodies for same |
| ES2594281T3 (es) | 2007-01-10 | 2016-12-19 | Purdue Research Foundation | Inhibidores polipeptídicos de HSP27 quinasa y usos de los mismos |
| US20100184049A1 (en) * | 2007-04-27 | 2010-07-22 | Steve Goodison | Glycoprotein Profiling of Bladder Cancer |
| WO2008151238A1 (en) * | 2007-06-04 | 2008-12-11 | The Johns Hopkins University | Biomarkers for prostate cancer |
| EP2171080A4 (de) * | 2007-06-12 | 2010-10-27 | Glaxosmithkline Llc | Verfahren zum nachweis von protein in plasma |
| US20100168382A1 (en) * | 2007-06-12 | 2010-07-01 | Vladimir Berezin | Neuroplastin derived peptides |
| EP2174134B1 (de) * | 2007-07-03 | 2013-10-09 | NorthEastern University | Biomarker für diabetes, obesität und/oder bluthochdruck |
| WO2009014450A1 (en) * | 2007-07-24 | 2009-01-29 | Sanare As | Novel peptides with anti-tumor activity |
| DK2185698T3 (en) | 2007-08-07 | 2015-07-27 | Purdue Research Foundation | Kinase Inhibitors and Uses thereof |
| AU2009208607B2 (en) * | 2008-01-31 | 2013-08-01 | Compugen Ltd. | Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics |
| US9327008B2 (en) | 2008-12-10 | 2016-05-03 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| US8395113B2 (en) | 2009-05-08 | 2013-03-12 | Thermo Finnigan Llc | Methods and systems for matching product ions to precursor in tandem mass spectrometry |
| CN102695716B (zh) * | 2009-07-14 | 2016-03-02 | 独立行政法人产业技术综合研究所 | 肝病病情指标糖链标记物 |
| US9890195B2 (en) | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| JP5756169B2 (ja) * | 2010-05-14 | 2015-07-29 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | タンパク質信頼値を計算するためのシステムおよび方法 |
| PL3260132T3 (pl) * | 2010-10-27 | 2022-08-08 | Takeda Pharmaceutical Company Limited | Peptydy fviii do wywoływania tolerancji immunologicznej oraz immunodiagnostyki |
| US9403889B2 (en) | 2010-11-29 | 2016-08-02 | Integrated Diagnostics, Inc. | Diagnostic lung cancer panel and methods for its use |
| US8772043B2 (en) | 2010-12-23 | 2014-07-08 | Pioneer Hi Bred International Inc | Universal peptide tags for transgene polypeptide analysis by mass spectrometry |
| CA2835806A1 (en) * | 2011-05-13 | 2012-11-22 | King's College London | Methods and compositions relating to platelet sensitivity |
| CA2838053A1 (en) | 2011-06-03 | 2012-12-06 | University Of South Alabama | Methods and compositions for detecting endometrial or ovarian cancer |
| US9506167B2 (en) | 2011-07-29 | 2016-11-29 | Ginkgo Bioworks, Inc. | Methods and systems for cell state quantification |
| US10226238B2 (en) | 2011-09-12 | 2019-03-12 | Creatics Llc | Non-invasive methods of detecting target molecules |
| CN103134874B (zh) * | 2011-12-01 | 2015-05-20 | 成都康弘生物科技有限公司 | 一种测定蛋白中糖基的方法 |
| US9304137B2 (en) | 2011-12-21 | 2016-04-05 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
| US11913957B2 (en) | 2011-12-21 | 2024-02-27 | Biodesix, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
| WO2013096845A2 (en) | 2011-12-21 | 2013-06-27 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
| MX365403B (es) | 2012-01-09 | 2019-05-31 | Serpin Pharma Llc | Peptidos y metodos para usarlos. |
| WO2013134636A1 (en) | 2012-03-09 | 2013-09-12 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| WO2014073708A1 (ja) * | 2012-11-06 | 2014-05-15 | 国立大学法人宮崎大学 | 新規ペプチドおよびその用途 |
| WO2014100717A2 (en) | 2012-12-21 | 2014-06-26 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
| CA2902841A1 (en) | 2013-03-13 | 2014-10-02 | Creatics Llc | Methods and compositions for detecting pancreatic cancer |
| GB201310150D0 (en) * | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Methods and compositions relating to alzheimer's disease |
| CN105793710B (zh) | 2013-07-26 | 2019-04-09 | 佰欧迪塞克斯公司 | 用于肺癌诊断的组合物、方法和试剂盒 |
| US9594085B2 (en) | 2014-02-03 | 2017-03-14 | Integrated Diagnostics, Inc. | Integrated quantification method for protein measurements in clinical proteomics |
| HRP20200967T1 (hr) | 2014-06-20 | 2020-10-16 | Immatics Biotechnologies Gmbh | Nova imunoterapija protiv nekoliko tumora krvi, posebice kronične limfoidne leukemije (cll) |
| GB201411037D0 (en) * | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
| WO2016038608A1 (en) * | 2014-09-08 | 2016-03-17 | Carmel Haifa University Economic Corporation Ltd. | Peptides derived from angiotensin receptor and use thereof |
| WO2016054114A1 (en) | 2014-09-29 | 2016-04-07 | The Regents Of The University Of California | Compositions for expanding regulatory t cells (treg), and treating autoimmune and inflammatory diseases and conditions |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| IL301919A (en) | 2015-03-27 | 2023-06-01 | Immatics Biotechnologies Gmbh | Innovative peptides and a combination of peptides for use in immunotherapy against various tumors |
| AU2016317726B2 (en) | 2015-08-28 | 2022-05-26 | Serpin Pharma, Llc | Methods for treatment of diseases |
| GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
| GB201520559D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| CN110114680A (zh) | 2016-05-05 | 2019-08-09 | 佰欧迪塞克斯公司 | 用于诊断肺癌的组合物、方法和试剂盒 |
| US9960027B2 (en) | 2016-05-25 | 2018-05-01 | Thermo Finnigan Llc | Analyzing a complex sample by MS/MS using isotopically-labeled standards |
| AU2018324195B2 (en) * | 2017-09-01 | 2024-12-12 | Venn Biosciences Corporation | Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring |
| ES2710321A1 (es) | 2017-10-20 | 2019-04-24 | Consejo Superior Investigacion | Adn polimerasas independientes de cebador y su uso para la sintesis de adn |
| WO2020223646A1 (en) | 2019-05-02 | 2020-11-05 | Creatics Llc | Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples |
| CN110563844A (zh) * | 2019-09-04 | 2019-12-13 | 华中农业大学 | 一种抗犬白介素31受体的多克隆抗体及其应用 |
| US12662518B2 (en) | 2019-09-09 | 2026-06-23 | The Wistar Institute Of Anatomy And Biology | Engineered peptide and peptide mimetic compositions and methods |
| ES2984813T3 (es) * | 2020-04-28 | 2024-10-31 | Janssen Pharmaceuticals Inc | Método para la identificación y la cuantificación de polisacáridos en composiciones de glicoconjugados complejas |
| US12105093B2 (en) | 2020-07-28 | 2024-10-01 | University Of Washington | Quantitation of GLA proteins by mass spectrometric analysis |
| EP4053559A1 (de) * | 2021-03-01 | 2022-09-07 | Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER) | Verfahren zur messung von protein c und aktiviertem protein c |
| WO2022232610A2 (en) * | 2021-04-29 | 2022-11-03 | Seer, Inc. | Peptide decorated nanoparticles for enrichment of specific protein subsets |
| CN113480629B (zh) * | 2021-06-16 | 2022-08-19 | 复旦大学 | 区分肝癌和正常人的末端唾液酸化异构糖肽标志物及其筛查方法 |
| CN115490763A (zh) * | 2021-06-18 | 2022-12-20 | 佛山热休生物技术有限公司 | Lum的表位肽及所述表位肽与热休克蛋白的复合物 |
| US11542340B1 (en) | 2021-10-29 | 2023-01-03 | Biodesix, Inc. | Antibodies targeting pulmonary nodule specific biomarkers and uses thereof |
| NL2030990B1 (en) * | 2022-02-17 | 2023-09-01 | Academisch Ziekenhuis Leiden | T cell receptors directed against jchain and uses thereof |
| WO2023164697A2 (en) * | 2022-02-28 | 2023-08-31 | PrognomIQ, Inc. | Glycoprotein assessment |
| EP4605011A2 (de) * | 2022-10-21 | 2025-08-27 | Quantum-Si Incorporated | Polypeptidyllinker |
| CN117969642B (zh) * | 2024-04-02 | 2024-07-23 | 浙江大学 | 一种植物n-糖链的精准相对定量分析方法及应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2226032B (en) * | 1988-12-16 | 1993-08-18 | Urs Heimgartner | Detection of glycoproteins |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5079336A (en) * | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5264563A (en) | 1990-08-24 | 1993-11-23 | Ixsys Inc. | Process for synthesizing oligonucleotides with random codons |
| GB9112504D0 (en) * | 1991-06-11 | 1991-07-31 | Merck Sharp & Dohme | Cell line |
| US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
| US5739386A (en) | 1994-06-23 | 1998-04-14 | Affymax Technologies N.V. | Photolabile compounds and methods for their use |
| EP0909277B2 (de) * | 1996-06-07 | 2008-12-24 | Poniard Pharmaceuticals, Inc. | Humanisierte antikörper die an das gleiche antigen wie antikörper nr-lu-13 binden und deren verwendung in "pretargeting" verfahren |
| US6328969B1 (en) * | 1996-12-10 | 2001-12-11 | Sloan-Kettering Institute For Cancer Research | Method and compositions for stimulation of an immune response to a differentiation antigen stimulated by an altered differentiation antigen |
| US6046013A (en) * | 1997-08-01 | 2000-04-04 | Gti | Process for identifying specific antibodies associated with HLA |
| ATE253126T1 (de) | 1998-08-25 | 2003-11-15 | Univ Washington | Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen |
| US6407210B1 (en) * | 1998-11-09 | 2002-06-18 | University Of Utah Research Foundation | Nematode neuromuscular junction GABA receptors and methods related thereto |
| WO2000073801A2 (en) * | 1999-05-28 | 2000-12-07 | Ludwig Institute For Cancer Research | Breast, gastric and prostate cancer associated antigens and uses therefor |
| WO2002052259A1 (en) | 2000-12-26 | 2002-07-04 | The Institute For Systems Biology | Rapid and quantitative proteome analysis and related methods |
| EP2295550A3 (de) * | 2001-04-30 | 2011-12-14 | Vertex Pharmaceuticals Incorporated | Kristallstrukturen von GSK-3-beta-Protein und -Proteinkomplexen und deren Verwendung |
| EP1432992A2 (de) * | 2001-09-27 | 2004-06-30 | Purdue Research Foundation | Kontrolle von isotopeneffekten während der analytfraktionierung |
| JP4583168B2 (ja) * | 2002-06-03 | 2010-11-17 | ザ インスティテュート フォー システムズ バイオロジー | 糖タンパク質を定量的プロテオ−ム分析する方法 |
| US7794947B2 (en) * | 2003-07-10 | 2010-09-14 | Institute For Systems Biology | Affinity capture of peptides by microarray and related methods |
| US7593336B2 (en) * | 2003-10-31 | 2009-09-22 | Brocade Communications Systems, Inc. | Logical ports in trunking |
| US7348416B2 (en) * | 2003-11-21 | 2008-03-25 | Applera Corporation | Selective capture and enrichment of proteins expressed on the cell surface |
-
2005
- 2005-05-20 EP EP05751819A patent/EP1766412B1/de not_active Expired - Lifetime
- 2005-05-20 US US11/134,871 patent/US20060141528A1/en not_active Abandoned
- 2005-05-20 DK DK05751819T patent/DK1766412T3/da active
- 2005-05-20 DE DE602005013670T patent/DE602005013670D1/de not_active Expired - Lifetime
- 2005-05-20 EP EP10012636A patent/EP2302393A1/de not_active Withdrawn
- 2005-05-20 EP EP09153474A patent/EP2093569A3/de not_active Withdrawn
- 2005-05-20 EP EP10012637A patent/EP2302394A1/de not_active Withdrawn
- 2005-05-20 WO PCT/US2005/017842 patent/WO2005114221A2/en not_active Ceased
- 2005-05-20 AT AT05751819T patent/ATE427499T1/de not_active IP Right Cessation
-
2010
- 2010-03-12 US US12/723,574 patent/US20100279382A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2093569A2 (de) | 2009-08-26 |
| EP2302393A8 (de) | 2011-08-03 |
| EP2302394A1 (de) | 2011-03-30 |
| EP2093569A3 (de) | 2009-11-11 |
| EP2302393A1 (de) | 2011-03-30 |
| DK1766412T3 (da) | 2009-05-25 |
| EP1766412B1 (de) | 2009-04-01 |
| WO2005114221A3 (en) | 2006-12-21 |
| WO2005114221A2 (en) | 2005-12-01 |
| EP1766412A2 (de) | 2007-03-28 |
| WO2005114221A8 (en) | 2006-05-04 |
| DE602005013670D1 (de) | 2009-05-14 |
| US20100279382A1 (en) | 2010-11-04 |
| US20060141528A1 (en) | 2006-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |