ATE427963T1 - Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern - Google Patents

Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern

Info

Publication number
ATE427963T1
ATE427963T1 AT04775280T AT04775280T ATE427963T1 AT E427963 T1 ATE427963 T1 AT E427963T1 AT 04775280 T AT04775280 T AT 04775280T AT 04775280 T AT04775280 T AT 04775280T AT E427963 T1 ATE427963 T1 AT E427963T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
antigens
antibodies specific
development
kits
Prior art date
Application number
AT04775280T
Other languages
English (en)
Inventor
Vsevolod Ivanovich Kiselev
Petr Georgiyevich Sveshnikov
Original Assignee
Vsevolod Ivanovich Kiselev
Petr Georgiyevich Sveshnikov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vsevolod Ivanovich Kiselev, Petr Georgiyevich Sveshnikov filed Critical Vsevolod Ivanovich Kiselev
Application granted granted Critical
Publication of ATE427963T1 publication Critical patent/ATE427963T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57575—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C07K16/084—Papillomaviridae (F); Polyomaviridae (F), e.g. SV40, BK virus or JC virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2872—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against prion molecules, e.g. CD230
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04775280T 2003-09-25 2004-09-24 Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern ATE427963T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2003128660/15A RU2251699C1 (ru) 2003-09-25 2003-09-25 Способ ранней и доклинической диагностики цервикального рака

Publications (1)

Publication Number Publication Date
ATE427963T1 true ATE427963T1 (de) 2009-04-15

Family

ID=34374510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04775280T ATE427963T1 (de) 2003-09-25 2004-09-24 Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern

Country Status (12)

Country Link
US (1) US20080267982A1 (de)
EP (1) EP1673393B1 (de)
JP (1) JP2007537705A (de)
KR (1) KR20060079239A (de)
CN (1) CN1886425A (de)
AT (1) ATE427963T1 (de)
AU (1) AU2004274368B2 (de)
CA (1) CA2539562A1 (de)
DE (1) DE602004020489D1 (de)
EA (1) EA010506B1 (de)
RU (1) RU2251699C1 (de)
WO (1) WO2005028510A2 (de)

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JP2006333801A (ja) * 2005-06-03 2006-12-14 Obihiro Univ Of Agriculture & Veterinary Medicine イヌ流産菌およびレプトスピラ菌の検出方法およびそれに用いるプライマーセット
GB0519198D0 (en) * 2005-09-20 2005-10-26 Univ Cambridge Tech Tse detection
US8916342B2 (en) 2006-11-13 2014-12-23 Oncohealth Corp. Identification of high grade or ≧ CIN2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (HPV) and HPV-associated cancers
US20100003704A1 (en) 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
RU2343485C1 (ru) * 2007-06-14 2009-01-10 Государственное образовательное учреждение высшего профессионального образования "Владивостокский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ВГМУ Росздрава) Способ диагностики рака шейки матки
RU2379690C1 (ru) * 2008-09-15 2010-01-20 Федеральное государственное учреждение "Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "УрНИИДВиИ Росмедтехнологий") Способ диагностики папилломавирусной инфекции
TWI507524B (zh) * 2009-11-30 2015-11-11 建南德克公司 診斷及治療腫瘤之組合物及方法
JP5819851B2 (ja) * 2010-01-08 2015-11-24 オンコヘルス コーポレーション Ｈｐｖ関連の癌の治療及びスクリーニングのための細胞に基づいた高処理能力ｈｐｖ免疫アッセイ
EP2601298B1 (de) 2010-08-02 2016-11-30 Regeneron Pharmaceuticals, Inc. Maüse, die vl domäne enthaltende bindende proteine machen
CN105861548B (zh) 2011-02-25 2020-01-10 瑞泽恩制药公司 Adam6小鼠
US20140255449A1 (en) * 2011-07-21 2014-09-11 Biotech Tools S.A. Dosage of dnak
ES2872081T3 (es) 2011-08-05 2021-11-02 Regeneron Pharma Ratones con cadena ligera universal humanizada
EP4074833A1 (de) 2011-10-17 2022-10-19 Regeneron Pharmaceuticals, Inc. Mäuse mit eingeschränkten schweren immunglobulinketten
SMT201900296T1 (it) 2011-12-20 2019-07-11 Regeneron Pharma Topi di catena leggera umanizzata
NZ703689A (en) 2012-06-12 2016-05-27 Regeneron Pharma Humanized non-human animals with restricted immunoglobulin heavy chain loci
CN102879584A (zh) * 2012-09-26 2013-01-16 中国人民解放军军事医学科学院基础医学研究所 一种人血液hsp70抗体胶体金标检测试纸条及其制备方法
RS57582B1 (sr) 2013-02-20 2018-11-30 Regeneron Pharma Nehumane životinje sa modifikovanim sekvencama imunoglobulinskog teškog lanca
AU2015230938C1 (en) 2014-03-21 2021-10-14 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
SG10201808083VA (en) 2014-03-21 2018-10-30 Regeneron Pharma Vl antigen binding proteins exhibiting distinct binding characteristics
CN107438622A (zh) 2015-03-19 2017-12-05 瑞泽恩制药公司 选择结合抗原的轻链可变区的非人动物
CN113512107A (zh) * 2021-03-13 2021-10-19 杭州市公安局刑事科学技术研究所 一种杀鼠灵完全抗原及其制备方法
CN122283148A (zh) * 2026-05-26 2026-06-26 天津天海新域生物科技有限公司 一种提升自身免疫性脑炎抗体诊断效能的检测试剂盒及制备方法

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DE4224542A1 (de) * 1992-07-24 1994-01-27 Deutsches Krebsforsch Verfahren zur Herstellung von monoklonalen MHC Klasse I-puls-Peptid-restringierten Antikörpern
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WO1997004080A1 (en) * 1995-07-14 1997-02-06 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel protein and monoclonal antibody specific thereto
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Also Published As

Publication number Publication date
RU2251699C1 (ru) 2005-05-10
EP1673393B1 (de) 2009-04-08
EA010506B1 (ru) 2008-10-30
CA2539562A1 (en) 2005-03-31
KR20060079239A (ko) 2006-07-05
AU2004274368A1 (en) 2005-03-31
US20080267982A1 (en) 2008-10-30
WO2005028510A3 (en) 2005-08-25
WO2005028510A2 (en) 2005-03-31
CN1886425A (zh) 2006-12-27
DE602004020489D1 (de) 2009-05-20
EP1673393A2 (de) 2006-06-28
JP2007537705A (ja) 2007-12-27
EA200600646A1 (ru) 2006-08-25
AU2004274368B2 (en) 2010-06-24

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