ATE427963T1 - Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern - Google Patents

Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern

Info

Publication number
ATE427963T1
ATE427963T1 AT04775280T AT04775280T ATE427963T1 AT E427963 T1 ATE427963 T1 AT E427963T1 AT 04775280 T AT04775280 T AT 04775280T AT 04775280 T AT04775280 T AT 04775280T AT E427963 T1 ATE427963 T1 AT E427963T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
antigens
antibodies specific
development
kits
Prior art date
Application number
AT04775280T
Other languages
English (en)
Inventor
Vsevolod Ivanovich Kiselev
Petr Georgiyevich Sveshnikov
Original Assignee
Vsevolod Ivanovich Kiselev
Petr Georgiyevich Sveshnikov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vsevolod Ivanovich Kiselev, Petr Georgiyevich Sveshnikov filed Critical Vsevolod Ivanovich Kiselev
Application granted granted Critical
Publication of ATE427963T1 publication Critical patent/ATE427963T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57575—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C07K16/084—Papillomaviridae (F); Polyomaviridae (F), e.g. SV40, BK virus or JC virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2872—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against prion molecules, e.g. CD230
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04775280T 2003-09-25 2004-09-24 Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern ATE427963T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2003128660/15A RU2251699C1 (ru) 2003-09-25 2003-09-25 Способ ранней и доклинической диагностики цервикального рака

Publications (1)

Publication Number Publication Date
ATE427963T1 true ATE427963T1 (de) 2009-04-15

Family

ID=34374510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04775280T ATE427963T1 (de) 2003-09-25 2004-09-24 Verfahren, kits und zusammensetzungen zur entwicklung und anwendung von fur antigene niedriger immunogenizitat spezifischen monoklonalen antikírpern

Country Status (12)

Country Link
US (1) US20080267982A1 (de)
EP (1) EP1673393B1 (de)
JP (1) JP2007537705A (de)
KR (1) KR20060079239A (de)
CN (1) CN1886425A (de)
AT (1) ATE427963T1 (de)
AU (1) AU2004274368B2 (de)
CA (1) CA2539562A1 (de)
DE (1) DE602004020489D1 (de)
EA (1) EA010506B1 (de)
RU (1) RU2251699C1 (de)
WO (1) WO2005028510A2 (de)

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JP2006333801A (ja) * 2005-06-03 2006-12-14 Obihiro Univ Of Agriculture & Veterinary Medicine イヌ流産菌およびレプトスピラ菌の検出方法およびそれに用いるプライマーセット
GB0519198D0 (en) * 2005-09-20 2005-10-26 Univ Cambridge Tech Tse detection
US8865162B2 (en) * 2008-06-13 2014-10-21 Oncohealth Corp. Monoclonal antibodies against HPV proteins
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
WO2010129821A1 (en) 2009-05-07 2010-11-11 Oncohealth Corporation Identification of high grade or ≥cin2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (hpv) and hpv-associated cancers
RU2343485C1 (ru) * 2007-06-14 2009-01-10 Государственное образовательное учреждение высшего профессионального образования "Владивостокский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ВГМУ Росздрава) Способ диагностики рака шейки матки
RU2379690C1 (ru) * 2008-09-15 2010-01-20 Федеральное государственное учреждение "Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "УрНИИДВиИ Росмедтехнологий") Способ диагностики папилломавирусной инфекции
TWI537383B (zh) * 2009-11-30 2016-06-11 建南德克公司 診斷及治療腫瘤之組合物及方法
US9128094B2 (en) 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers
EP3960865A1 (de) 2010-08-02 2022-03-02 Regeneron Pharmaceuticals, Inc. Mäuse, die bindeproteine mit vl-domänen produzieren
ME03732B (de) 2011-02-25 2021-01-20 Regeneron Pharma ADAM6 Mäuse
EP2734231A1 (de) * 2011-07-21 2014-05-28 Biotech Tools S.A. Dosierung von dnak
HRP20192255T1 (hr) 2011-08-05 2020-03-06 Regeneron Pharmaceuticals, Inc. Humanizirani miševi s univerzalnim lakim lancem
HRP20220253T1 (hr) 2011-10-17 2022-04-29 Regeneron Pharmaceuticals, Inc. Miševi s ograničenim teškim lancem imunoglobulina
ME03477B (de) 2011-12-20 2020-01-20 Regeneron Pharma Humanisierte leichtkettige mäuse
KR102484480B1 (ko) 2012-06-12 2023-01-04 리제너론 파마슈티칼스 인코포레이티드 제한된 면역글로불린 중쇄 유전자좌를 가지는 인간화된 비-인간 동물
CN102879584A (zh) * 2012-09-26 2013-01-16 中国人民解放军军事医学科学院基础医学研究所 一种人血液hsp70抗体胶体金标检测试纸条及其制备方法
LT2840892T (lt) 2013-02-20 2018-07-25 Regeneron Pharmaceuticals, Inc. Nežmogaus tipo gyvūnai su modifikuotomis imunoglobulino sunkiųjų grandinių sekomis
SG10201808225TA (en) 2014-03-21 2018-10-30 Regeneron Pharma Non-human animals that make single domain binding proteins
BR112016021679A2 (pt) 2014-03-21 2018-12-04 Regeneron Pharmaceuticals, Inc. proteína de ligação ao antígeno, métodos de produção de uma proteína de ligação ao antígeno e de identificação de uma ou mais proteínas de ligação ao antígeno, hibridoma, ácido nucleico, célula, e, animal não humano geneticamente modificado.
HK1250038A1 (zh) 2015-03-19 2018-11-23 瑞泽恩制药公司 选择结合抗原的轻链可变区的非人动物
CN113512107A (zh) * 2021-03-13 2021-10-19 杭州市公安局刑事科学技术研究所 一种杀鼠灵完全抗原及其制备方法

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PT523391E (pt) * 1991-07-13 2003-08-29 Dade Behring Marburg Gmbh Utilizacao dos peptidos derivados dos genes hpv-16 e6 e e7 para fins de diagnostico
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AR004464A1 (es) * 1994-11-14 1998-12-16 Merck Sharp & Dohme Un metodo para producir una proteina de capside de papilomavirus
JPH0984589A (ja) * 1995-07-14 1997-03-31 Fuji Yakuhin Kogyo Kk 新規なタンパク質
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WO1997004080A1 (en) * 1995-07-14 1997-02-06 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel protein and monoclonal antibody specific thereto
JP3174492B2 (ja) * 1995-11-09 2001-06-11 富士薬品工業株式会社 ウサギｍｍｐ−３に対するモノクローナル抗体及びそれを用いた免疫学的測定法
US6319503B1 (en) * 1998-02-19 2001-11-20 Proteinix Company Heat shock fusion-based vaccine system
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Also Published As

Publication number Publication date
WO2005028510A3 (en) 2005-08-25
EA010506B1 (ru) 2008-10-30
US20080267982A1 (en) 2008-10-30
EP1673393A2 (de) 2006-06-28
EA200600646A1 (ru) 2006-08-25
CA2539562A1 (en) 2005-03-31
JP2007537705A (ja) 2007-12-27
AU2004274368A1 (en) 2005-03-31
KR20060079239A (ko) 2006-07-05
RU2251699C1 (ru) 2005-05-10
EP1673393B1 (de) 2009-04-08
DE602004020489D1 (de) 2009-05-20
CN1886425A (zh) 2006-12-27
WO2005028510A2 (en) 2005-03-31
AU2004274368B2 (en) 2010-06-24

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