ATE429449T1 - Anti-fas-ligand antikörper und testmethode unter verwendung derselben - Google Patents

Anti-fas-ligand antikörper und testmethode unter verwendung derselben

Info

Publication number
ATE429449T1
ATE429449T1 AT96921136T AT96921136T ATE429449T1 AT E429449 T1 ATE429449 T1 AT E429449T1 AT 96921136 T AT96921136 T AT 96921136T AT 96921136 T AT96921136 T AT 96921136T AT E429449 T1 ATE429449 T1 AT E429449T1
Authority
AT
Austria
Prior art keywords
fas ligand
same
testing method
ligand antibodies
hepatitis
Prior art date
Application number
AT96921136T
Other languages
English (en)
Inventor
Kamon Shirakawa
Tomokazu Matsusue
Shigekazu Nagata
Man Co
Maximiliano Vasquez
Original Assignee
Mochida Pharm Co Ltd
Osaka Bioscience Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd, Osaka Bioscience Inst filed Critical Mochida Pharm Co Ltd
Priority claimed from PCT/JP1996/001820 external-priority patent/WO1997002290A1/ja
Application granted granted Critical
Publication of ATE429449T1 publication Critical patent/ATE429449T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT96921136T 1995-06-30 1996-07-01 Anti-fas-ligand antikörper und testmethode unter verwendung derselben ATE429449T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18848095 1995-06-30
US08/649,100 US6114507A (en) 1995-06-30 1996-05-17 Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody
PCT/JP1996/001820 WO1997002290A1 (en) 1995-06-30 1996-07-01 ANTIFas LIGAND ANTIBODIES AND ASSAY METHOD BY USING THE SAME

Publications (1)

Publication Number Publication Date
ATE429449T1 true ATE429449T1 (de) 2009-05-15

Family

ID=16224475

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921136T ATE429449T1 (de) 1995-06-30 1996-07-01 Anti-fas-ligand antikörper und testmethode unter verwendung derselben

Country Status (4)

Country Link
US (1) US6114507A (de)
KR (1) KR100496335B1 (de)
AT (1) ATE429449T1 (de)
DE (1) DE69637909D1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU725329B2 (en) * 1996-09-02 2000-10-12 Ko Okumura Humanized immunoglobulin reacting specifically with Fas ligand or active fragments thereof and region inducing apoptosis originating in Fas ligand
CA2309598A1 (en) * 1997-11-10 1999-05-20 Mochida Pharmaceutical Co., Ltd. Preventives and remedies for diffuse lung disease
US7063960B2 (en) 1997-12-12 2006-06-20 The Rockefeller University Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof
DE10054279A1 (de) * 2000-11-02 2002-05-16 Apotech Res & Dev Ltd Verwendung von Liganden von Todesrezeptoren oder RIP zur Auslösung des Caspase-unabhängigen Zelltods und Verbindungen zur Inhibition des Caspase-unabhängigen Zelltods
CN1283662C (zh) * 2002-03-21 2006-11-08 伊莱利利公司 拮抗性抗hFAS配基人类抗体及其片段
US20070077603A1 (en) * 2005-07-12 2007-04-05 Heeb Mary J Elisa to detect multimeric forms of a protein
LT2631248T (lt) * 2007-06-15 2018-04-25 Medigene Ag Navikų gydymas, naudojant specifinį anti-l1 antikūną
JP2011506371A (ja) * 2007-12-12 2011-03-03 ピンチェル ソチエタ・レスポンサビリタ・リミタータ 抗Ｆａｓリガンド抗体を含有する天疱瘡の治療薬
AU2008201871A1 (en) * 2008-04-16 2009-11-26 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Inhibition of angiogenesis and tumor metastasis
RU2556818C2 (ru) * 2008-12-12 2015-07-20 Пинчел Срл СРЕДСТВА ДЛЯ ЛЕЧЕНИЯ ПУЗЫРЧАТКИ, СОДЕРЖАЩИЕ АНТИТЕЛА ПРОТИВ ЛИГАНДА Fas
JO3437B1 (ar) 2009-10-30 2019-10-20 Esai R & D Man Co Ltd أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
HUE037408T2 (hu) 2011-06-10 2018-08-28 Univ Oregon Health & Science CMV glikoproteinek és rekombináns vektorok
CA2789539A1 (en) 2011-09-12 2013-03-12 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (de) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CA3018792C (en) * 2016-03-31 2023-03-28 Eli Lilly And Company Il-21 antibodies and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08127594A (ja) * 1993-11-10 1996-05-21 Mochida Pharmaceut Co Ltd Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ
ATE387458T1 (de) * 1994-01-07 2008-03-15 Mochida Pharm Co Ltd Fas-antigenbindender ligand
CA2215905A1 (en) * 1995-03-20 1996-09-26 Sumitomo Electric Industries, Ltd. Monoclonal antibody reacting specifically with fas ligand and process for producing the same

Also Published As

Publication number Publication date
KR100496335B1 (ko) 2006-04-17
DE69637909D1 (de) 2009-06-04
US6114507A (en) 2000-09-05
KR19990028638A (ko) 1999-04-15

Similar Documents

Publication Publication Date Title
ATE429449T1 (de) Anti-fas-ligand antikörper und testmethode unter verwendung derselben
EP0914155A4 (de) Spezifische monoklonale antikörperfür die extrazelluläre domäne von protasta-spezifischem membranantigen
EP0314402A3 (de) Monoklonale Antikörper gegen menschliches Interleukin-4 und Hybridomen, die sie produzieren
MX9300913A (es) Cloneo y expresion de anticuerpos monoclonales humanizados contra interleuquina-4 humana.
DE3854496D1 (de) Peptide und antikörper, die die bindung von blutplättchen verhindern.
FI960268L (fi) Menetelmä sairauden diagnosoimiseksi määrittämällä GAGE-tuumorihyljintäantigeenin prekursorien ilmentymistä
ATE464374T1 (de) Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen
FI964862A7 (fi) FLT4-reseptorityrosiinikinaasi ja sen käyttö diagnostiikassa ja terapiassa
DE69333076D1 (de) Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis
ID25978A (id) Antibodi anti-fas
NO163920C (no) Fremgangsmaate for bestemmelse av pivka-ii i fysiologiske proever.
DK0412700T3 (da) Fremgangsmåde til isolering af føtale cytrophoblastceller
WO2004015420A8 (en) Method for diagnosing multiple sclerosis
ES8501630A1 (es) Un metodo para detectar o vigilar el estado de una condicion patologica humana que implica proteina de tejido conjuntivo.
ID20117A (id) Antibodi anti-fas
NO174110C (no) Monoklonalt antistoff til anvendelse in vitro for diagnose av maligne tumor- eller akutte inflammasjonssykdommer, og som er spesifikt for N-acetyl-neuraminsyre i hybridom som produserer antistoffet
EP0245052A3 (de) Feststellung einer Entzündung und Antikörper dazu
DE3684223D1 (de) Monoklonale antikoerper.
SE9602234D0 (sv) A novel diagnostic method utilizing ECP, and reagents to be used in the methods
ES2125248T3 (es) Metodo de deteccion de una infeccion cmv.
EP0721958A3 (de) Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor
WO1990008956A1 (en) Detection of human tissue factor activator
IE882250L (en) Monoclonal antibodies and methods for diagnosis of Phytophthora infection
ATE123309T1 (de) Monoklonale, gegen eca gerichtete antikörper und ihre verwendung.
NL7713952A (nl) Radio-immunologische methode voor het bepalen van de schildklierfunktie door een in vitro onderzoek in bloedserum.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties