JO3437B1 - أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها - Google Patents

أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها

Info

Publication number
JO3437B1
JO3437B1 JOP/2010/0374A JOP20100374A JO3437B1 JO 3437 B1 JO3437 B1 JO 3437B1 JO P20100374 A JOP20100374 A JO P20100374A JO 3437 B1 JO3437 B1 JO 3437B1
Authority
JO
Jordan
Prior art keywords
antibodies
human
fractalkin
enhanced anti
enhanced
Prior art date
Application number
JOP/2010/0374A
Other languages
English (en)
Inventor
Nishimura Miyuki
Kawano Tetsu
Imai Toshio
Sakamoto Yoshimasa
Original Assignee
Esai R & D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3437(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Esai R & D Man Co Ltd filed Critical Esai R & D Man Co Ltd
Application granted granted Critical
Publication of JO3437B1 publication Critical patent/JO3437B1/ar

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

يتعلق الاختراع الحالي بتركيبات وطرق تتعلق بأجسام مضادة معدة للاستخدام البشري وأجزاء رابطة لـ FKN منها والتي ترتبط بفراكتالكين.
JOP/2010/0374A 2009-10-30 2010-10-27 أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها JO3437B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25652109P 2009-10-30 2009-10-30

Publications (1)

Publication Number Publication Date
JO3437B1 true JO3437B1 (ar) 2019-10-20

Family

ID=43922220

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2010/0374A JO3437B1 (ar) 2009-10-30 2010-10-27 أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها

Country Status (33)

Country Link
US (1) US8932592B2 (ar)
EP (1) EP2493930B1 (ar)
JP (2) JP5631991B2 (ar)
KR (2) KR102099596B1 (ar)
CN (1) CN102597003B (ar)
AR (2) AR078796A1 (ar)
AU (1) AU2010312408B2 (ar)
BR (1) BR112012010266A2 (ar)
CA (1) CA2778895C (ar)
CL (2) CL2012001143A1 (ar)
CY (1) CY1121167T1 (ar)
DK (1) DK2493930T3 (ar)
ES (1) ES2698389T3 (ar)
HR (1) HRP20181973T1 (ar)
HU (1) HUE041952T2 (ar)
IL (1) IL219470A (ar)
JO (1) JO3437B1 (ar)
LT (1) LT2493930T (ar)
MX (1) MX2012005052A (ar)
MY (1) MY158481A (ar)
NZ (1) NZ599779A (ar)
PE (1) PE20121645A1 (ar)
PH (1) PH12012500828A1 (ar)
PL (1) PL2493930T3 (ar)
PT (1) PT2493930T (ar)
RS (1) RS58142B1 (ar)
RU (1) RU2569109C2 (ar)
SI (1) SI2493930T1 (ar)
SM (1) SMT201800637T1 (ar)
TW (1) TWI414308B (ar)
UA (1) UA105073C2 (ar)
WO (1) WO2011052799A1 (ar)
ZA (1) ZA201203002B (ar)

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MY189836A (en) 2014-11-21 2022-03-11 Bristol Myers Squibb Co Antibodies against cd73 and uses thereof
JP6668345B2 (ja) 2014-11-21 2020-03-18 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 修飾された重鎖定常領域を含む抗体
EP3159007A1 (en) 2015-10-19 2017-04-26 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating rheumatoid arthritis
JP2017154975A (ja) * 2016-02-29 2017-09-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
JP2018070473A (ja) * 2016-10-26 2018-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 関節リウマチを治療するための医薬組成物
JP2018177701A (ja) * 2017-04-14 2018-11-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
US20220196674A1 (en) * 2019-04-17 2022-06-23 Abdolamir Landi Treatment of autoimmune liver disease
US20220205980A1 (en) * 2019-04-23 2022-06-30 Eisai R&D Management Co., Ltd. Biomarker for rheumatoid arthritis treatment
KR20220110827A (ko) * 2019-12-09 2022-08-09 알렉시온 파마슈티칼스, 인코포레이티드 시신경척수염 스펙트럼 장애의 치료를 위한 항-c5 항체
CN113087795B (zh) * 2019-12-23 2025-06-10 上海普铭生物科技有限公司 针对趋化因子cx3cl1的抗体及其应用
WO2022092183A1 (ja) 2020-10-30 2022-05-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 医薬組成物
CN121537534B (zh) * 2026-01-22 2026-04-07 华中科技大学同济医学院附属协和医院 靶向cx3cl1的嵌合抗原受体-巨噬细胞及在gjb2突变相关遗传性耳聋治疗中的应用

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Also Published As

Publication number Publication date
WO2011052799A1 (en) 2011-05-05
DK2493930T3 (en) 2018-12-17
US20120213799A1 (en) 2012-08-23
AU2010312408B2 (en) 2015-07-09
AR078796A1 (es) 2011-12-07
EP2493930B1 (en) 2018-09-19
CL2015000114A1 (es) 2015-04-10
TW201127401A (en) 2011-08-16
PT2493930T (pt) 2018-11-29
US8932592B2 (en) 2015-01-13
CN102597003B (zh) 2016-03-23
HUE041952T2 (hu) 2019-06-28
KR20160066055A (ko) 2016-06-09
CA2778895C (en) 2018-08-07
CA2778895A1 (en) 2011-05-05
SI2493930T1 (sl) 2018-12-31
PH12012500828A1 (en) 2013-01-07
KR101627605B1 (ko) 2016-06-07
AR109533A2 (es) 2018-12-19
ZA201203002B (en) 2013-06-26
TWI414308B (zh) 2013-11-11
IL219470A (en) 2017-10-31
JP2015027304A (ja) 2015-02-12
PE20121645A1 (es) 2012-12-06
CN102597003A (zh) 2012-07-18
JP2013509158A (ja) 2013-03-14
KR20120104560A (ko) 2012-09-21
MY158481A (en) 2016-10-14
PL2493930T3 (pl) 2019-03-29
MX2012005052A (es) 2012-05-29
BR112012010266A2 (pt) 2016-12-06
RS58142B1 (sr) 2019-02-28
KR102099596B1 (ko) 2020-04-10
ES2698389T3 (es) 2019-02-04
CY1121167T1 (el) 2020-05-29
NZ599779A (en) 2014-03-28
EP2493930A4 (en) 2013-12-04
JP5631991B2 (ja) 2014-11-26
SMT201800637T1 (it) 2019-01-11
RU2012122203A (ru) 2013-12-10
HRP20181973T1 (hr) 2019-01-25
IL219470A0 (en) 2012-06-28
AU2010312408A1 (en) 2012-06-21
EP2493930A1 (en) 2012-09-05
CL2012001143A1 (es) 2012-10-05
RU2569109C2 (ru) 2015-11-20
LT2493930T (lt) 2019-01-10
UA105073C2 (uk) 2014-04-10

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