ATE429928T1 - Proteinartige adjuvantien - Google Patents

Proteinartige adjuvantien

Info

Publication number: ATE429928T1
Authority: AT; Austria
Prior art keywords: immune response; modulated immune; alum; genetically; antigen
Prior art date: 1994-06-10

Application number

AT01201610T

Other languages

English (en)

Inventor

Diane M Gajewczyk

Heather A Boux

Anton Novak

Michel H Klein

Original Assignee

Sanofi Pasteur Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-10

Filing date

1995-06-08

Publication date

2009-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22979642&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE429928(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-06-08 Application filed by Sanofi Pasteur Ltd filed Critical Sanofi Pasteur Ltd

2009-05-15 Application granted granted Critical

2009-05-15 Publication of ATE429928T1 publication Critical patent/ATE429928T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

AT01201610T 1994-06-10 1995-06-08 Proteinartige adjuvantien ATE429928T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US25822894A	1994-06-10	1994-06-10

Publications (1)

Publication Number	Publication Date
ATE429928T1 true ATE429928T1 (de)	2009-05-15

Family

ID=22979642

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT01201610T ATE429928T1 (de)	1994-06-10	1995-06-08	Proteinartige adjuvantien
AT95924122T ATE219686T1 (de)	1994-06-10	1995-06-08	Proteinartige adjuvantien

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT95924122T ATE219686T1 (de)	1994-06-10	1995-06-08	Proteinartige adjuvantien

Country Status (10)

Country	Link
US (2)	US20030072774A1 (de)
EP (3)	EP1149589B1 (de)
AT (2)	ATE429928T1 (de)
AU (1)	AU2876595A (de)
CA (1)	CA2192454A1 (de)
DE (2)	DE69527202T3 (de)
DK (2)	DK1149589T3 (de)
ES (2)	ES2179105T5 (de)
PT (2)	PT1149589E (de)
WO (1)	WO1995034323A2 (de)

Families Citing this family (37)

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GB9513371D0 (en)	1995-06-30	1995-09-06	Biocine Spa	Immunogenic detoxified mutant toxins
DE69434000T3 (de)	1993-10-05	2008-11-06	UCB Pharma Ltd., Slough	Impfstoffzusammensetzungen
GB9326174D0 (en) *	1993-12-22	1994-02-23	Biocine Sclavo	Mucosal adjuvant
US20030072774A1 (en) *	1994-06-10	2003-04-17	Diane M. Gajewczyk	Proteinaceous adjuvants
GB9500788D0 (en) *	1995-01-16	1995-03-08	Medeva Holdings Bv	Vaccine compositions
US6020182A (en)	1996-07-12	2000-02-01	Connaught Laboratories Limited	Subunit respiratory syncytial virus vaccine preparation
GB9622660D0 (en)	1996-10-31	1997-01-08	Biocine Spa	Immunogenic detoxified mutant toxin
EP1486215A3 (de) *	1997-03-21	2006-04-12	Chiron Corporation	Detoxifizierte Mutanten bakterieller ADP-ribosylierender Toxine als parenterale Adjuvantien
US6818222B1 (en)	1997-03-21	2004-11-16	Chiron Corporation	Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
DE69939943D1 (de) *	1998-10-21	2009-01-02	Kitasato Inst	Attenuierte Toxine als Adjuvantien
NZ512980A (en)	1998-12-17	2003-07-25	Aventis Pasteur	Multivalent immunogenic composition containing RSV subunit composition and influenza virus preparation
US7115730B1 (en)	1999-04-27	2006-10-03	Chiron Srl	Immunogenic detoxified mutant E. coli LT-A-toxin
CA2388337C (en)	1999-10-22	2013-01-08	Aventis Pasteur Limited	Method of inducing and/or enhancing an immune response to tumor antigens
EP1792995A3 (de)	2000-05-08	2007-06-13	Sanofi Pasteur Limited	Chlamydia Antigene, entsprechende DNS Fragmente und ihre Verwendungen
DK1282702T3 (da)	2000-05-10	2007-04-02	Sanofi Pasteur Ltd	Immunogene polypeptider, som er kodet af KAGE-minigener, og anvendelser deraf
ES2284681T3 (es)	2000-08-25	2007-11-16	Aventis Pasteur Limited	Epitopos de oligosacaridos del nucleo de lipopolisacaridos de maemophilus influenzae como vacunas para la prevencion de infecciones por haemophilus influenzae.
AU2002346249B2 (en)	2001-06-07	2007-03-15	The Regents Of The University Of Colorado	Mutant Forms of Cholera Holotoxin as an Adjuvant
US7332174B2 (en) *	2001-06-07	2008-02-19	Wyeth Holdings Corporation	Mutant forms of cholera holotoxin as an adjuvant
US7977314B2 (en)	2005-12-02	2011-07-12	Amorfix Life Sciences Limited	Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
CN101688194B (zh)	2007-05-23	2013-09-11	Uab研究基金会	去毒的肺炎球菌神经氨酸酶及其用途
ES2528648T3 (es)	2007-09-11	2015-02-11	University Of Guelph	Inmunógenos polisacáridos de la Clostridium Difficile
WO2009039125A1 (en) *	2007-09-17	2009-03-26	The Schepens Eye Research Institute, Inc.	Use of ocular neuropeptides as immune adjuvants
US8210944B2 (en) *	2007-10-29	2012-07-03	Igt	Gaming system having display device with changeable wheel
JP5070006B2 (ja) *	2007-11-02	2012-11-07	株式会社オハラ	結晶化ガラス
MX2011006922A (es)	2008-12-24	2012-06-12	Netherlands Vaccine Inst	Polipeptidos de neumolisina (ply) modificada a partir de streptococcus pneumonia.
US20140093556A1 (en)	2011-01-28	2014-04-03	Sanofi Pasteur Sa	Immunological Compositions Against HIV
BR112014014950B1 (pt) *	2011-12-21	2022-03-29	Bionet-Asia, Co. Ltd	Cepa de bordetella pertussis geneticamente modificada, e, métodos para produzir uma cepa de bordetella pertussis modificada e para produzir antígenos de bordetella pertussis
WO2014140938A2 (en)	2013-03-14	2014-09-18	Centre Hospitalier Universitaire Vaudois	Immunological methods
EP3185896B1 (de)	2014-06-20	2025-04-02	University of Saskatchewan	Exotoxin/thermolysinzusammensetzungen sowie verfahren und verwendung zur vorbeugung und behandlung von hufrehe
AU2016353553B2 (en)	2015-11-09	2022-01-20	The University Of British Columbia	Amyloid beta epitopes and antibodies thereto
EP3374381A4 (de)	2015-11-09	2019-05-15	The University Of British Columbia	Epitope in der amyloid-beta-mittelregion und konformativ selektive antikörper dazu
KR102776187B1 (ko)	2015-11-09	2025-03-07	더 유니버시티 오브 브리티쉬 콜롬비아	아밀로이드 베타에서의 n-말단 에피토프 및 이에 형태적으로-선택적인 항체
CN109476729A (zh)	2016-07-18	2019-03-15	英属哥伦比亚大学	淀粉样蛋白β的抗体
US20180125920A1 (en)	2016-11-09	2018-05-10	The University Of British Columbia	Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
US12286469B2 (en)	2017-07-18	2025-04-29	The University Of British Columbia	Humanized antibodies binding to amyloid-beta (A-beta)
IT201900007060A1 (it)	2019-05-21	2020-11-21	St Superiore Di Sanita	Cellule tumorali ingegnerizzate e loro usi
IT201900012540A1 (it)	2019-07-22	2021-01-22	Humanitas Mirasole Spa	Inibitori di CHI3L1 e loro usi

Family Cites Families (20)

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GB2144129B (en) *	1981-08-24	1985-10-09	Vilas V Likhite	Antigens as immunostimulant adjuvants
KR0168039B1 (ko) *	1987-09-04	1999-01-15	로버트 디. 웨스트	재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신
GB8727489D0 (en)	1987-11-24	1987-12-23	Connaught Lab	Detoxification of pertussis toxin
US5244657A (en) *	1987-11-24	1993-09-14	Connaught Laboratories Limited	Genetic detoxification of pertussis toxin
US5332583A (en) *	1987-11-24	1994-07-26	Connaught Laboratories Limited	Vaccine containing genetically-detoxified pertussis holotoxin
US5221618A (en)	1987-11-24	1993-06-22	Connaught Laboratories Limited	Genetic detoxification of pertussis toxin
US5358868A (en) *	1987-11-24	1994-10-25	Connaught Laboratories Limited	Genetic detoxification of pertussis toxin
JP2849632B2 (ja)	1988-04-08	1999-01-20	社団法人北里研究所	ワクチン製剤
AP8900132A0 (en) *	1988-07-22	1991-01-14	Smithkline Biolog	Bordetella pertussis vaccine
JPH03135923A (ja) *	1989-10-20	1991-06-10	Chemo Sero Therapeut Res Inst	百日咳毒素ｂオリゴマーの構成サブユニットを含有する経鼻接種ワクチン
US5786189A (en) *	1989-11-29	1998-07-28	Smithkline Beecham Biologicals (S.A.)	Vaccine
IT1248735B (it) *	1990-06-21	1995-01-26	Sclavo Spa	Vaccini acellulari contro la pertosse
DE69434000T3 (de) *	1993-10-05	2008-11-06	UCB Pharma Ltd., Slough	Impfstoffzusammensetzungen
US20030072774A1 (en) *	1994-06-10	2003-04-17	Diane M. Gajewczyk	Proteinaceous adjuvants
US5932714A (en) *	1995-02-23	1999-08-03	Connaught Laboratories Limited	Expression of gene products from genetically manipulated strains of Bordetella
JPH11121079A (ja) *	1997-10-20	1999-04-30	Yazaki Corp	圧接コネクタ及び圧接コネクタの組立方法
AU2001271268A1 (en) *	2000-05-19	2001-12-03	The Administrators Of The Tulane Educational Fund	Hybrid lt-a/ct-b holotoxin for use as an adjuvant
GB0118249D0 (en) *	2001-07-26	2001-09-19	Chiron Spa	Histidine vaccines
WO2003063759A2 (en) *	2002-01-31	2003-08-07	Peptor Ltd.	Hsp peptides and analogs for modulation of immune responses via antigen presenting cells
US6861410B1 (en) *	2002-03-21	2005-03-01	Chiron Corporation	Immunological adjuvant compositions

1995
- 1995-06-07 US US08/481,878 patent/US20030072774A1/en not_active Abandoned
- 1995-06-08 ES ES95924122T patent/ES2179105T5/es not_active Expired - Lifetime
- 1995-06-08 PT PT01201610T patent/PT1149589E/pt unknown
- 1995-06-08 EP EP01201610A patent/EP1149589B1/de not_active Expired - Lifetime
- 1995-06-08 US US08/750,378 patent/US7105161B1/en not_active Expired - Fee Related
- 1995-06-08 EP EP01201598A patent/EP1149588A1/de not_active Withdrawn
- 1995-06-08 PT PT95924122T patent/PT764029E/pt unknown
- 1995-06-08 EP EP95924122A patent/EP0764029B2/de not_active Expired - Lifetime
- 1995-06-08 DE DE69527202T patent/DE69527202T3/de not_active Expired - Lifetime
- 1995-06-08 ES ES01201610T patent/ES2325475T3/es not_active Expired - Lifetime
- 1995-06-08 CA CA002192454A patent/CA2192454A1/en not_active Abandoned
- 1995-06-08 AU AU28765/95A patent/AU2876595A/en not_active Abandoned
- 1995-06-08 DK DK01201610T patent/DK1149589T3/da active
- 1995-06-08 WO PCT/CA1995/000341 patent/WO1995034323A2/en not_active Ceased
- 1995-06-08 AT AT01201610T patent/ATE429928T1/de active
- 1995-06-08 DE DE69535943T patent/DE69535943D1/de not_active Expired - Lifetime
- 1995-06-08 DK DK95924122T patent/DK0764029T4/da active
- 1995-06-08 AT AT95924122T patent/ATE219686T1/de active

Also Published As

Publication number	Publication date
DK0764029T3 (da)	2002-10-21
WO1995034323A3 (en)	1996-01-18
DK0764029T4 (da)	2008-07-28
PT1149589E (pt)	2009-07-28
DK1149589T3 (da)	2009-08-17
ES2325475T3 (es)	2009-09-07
EP0764029B2 (de)	2008-03-26
ES2179105T3 (es)	2003-01-16
EP1149588A1 (de)	2001-10-31
PT764029E (pt)	2002-10-31
AU2876595A (en)	1996-01-05
EP0764029B1 (de)	2002-06-26
DE69527202T3 (de)	2008-07-31
WO1995034323A2 (en)	1995-12-21
CA2192454A1 (en)	1995-12-21
DE69527202T2 (de)	2002-12-05
EP0764029A1 (de)	1997-03-26
DE69535943D1 (de)	2009-06-10
DE69527202D1 (de)	2002-08-01
EP1149589B1 (de)	2009-04-29
US7105161B1 (en)	2006-09-12
US20030072774A1 (en)	2003-04-17
EP1149589A1 (de)	2001-10-31
ES2179105T5 (es)	2008-06-16
ATE219686T1 (de)	2002-07-15

Legal Events

Date

Code

Title

Description

2009-12-15

UEP

Publication of translation of european patent specification

Ref document number: 1149589

Country of ref document: EP

Publication	Publication Date	Title
ATE219686T1 (de)	2002-07-15	Proteinartige adjuvantien
NO930938L (no)	1993-03-16	Forbedrede vaksiner
AU3526995A (en)	1996-04-26	Vaccine compositions
AU4188100A (en)	2000-11-14	Dry formulation for transcutaneous immunization
IS4518A (is)	1999-01-10	Nýtt lyfjaform fyrir bóluefni
MA25824A1 (fr)	2003-07-01	Compostion de vaccin polyvalente
DK1459766T3 (da)	2008-10-13	Adjuvanssammensætninger til forstærkning af immunresponser på polynukleotidbaserede vacciner
KR950701822A (ko)	1995-05-17	간염B 표면 항원 및 다른 항원으로 구성된 조합 백신(Combined vaccines comprising hepatitis B surface antigen and other antines)
BR9710460A (pt)	1999-08-17	Composi-Æo imunolÄgica multi-valente e seu uso em vacinas
ATE489968T1 (de)	2010-12-15	Proteosom-liposaccharid-vakzine-adjuvans
NO970993D0 (no)	1997-03-04	Mutant enterotoksin som er effektiv som en ikke-toksisk oral adjuvant
BR9510223A (pt)	1997-12-30	Adjuvante para vacinas utilização de um polissacarideo lipidico processo para preparar uma cacina em emulsão e vacina
WO2001068129A3 (de)	2002-03-14	Adjuvans für vakzinen
LU91595I2 (fr)	2009-10-12	Combinaison d'anatoxine diphtérique, d'anatoxine tétanique, d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine et de polyoside capsulaire d'haemophilus influenzae type b (InfanrixHib)
BR0111834A (pt)	2003-07-08	Composições adjuvante e imunogênica, e, método para eliciar uma resposta imune a um antìgeno
PT792165E (pt)	2004-02-27	Composicoes imunogenicas
NO924271L (no)	1993-01-07	Vaksiner med forbedret immunogenisitet
ATE329615T1 (de)	2006-07-15	Borrelia burgdorferi bacterin
DK1223975T3 (da)	2009-08-31	Mukosale DTPa-vacciner
AU7960101A (en)	2002-02-18	Parenteral vaccine formulations and uses thereof
EP0591384A4 (de)	1995-01-18	Abgeschwächter rückmutierter virusimpfstoff gegen mareks krankheit serotyp-1.
ATE177010T1 (de)	1999-03-15	Immunverstärkung von impfstoffen, besonders von impfstoffen gegen schweinepleuropneumonie
RU93005000A (ru)	1996-10-27	Композиция вакцин, способ ее получения, способ исключения иммунной реакции