ATE430165T1 - Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten - Google Patents

Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten

Info

Publication number: ATE430165T1
Authority: AT; Austria
Prior art keywords: peptides; integrin binding; treatment methods; binding motif; sequences
Prior art date: 2000-08-16

Application number

AT01965941T

Other languages

English (en)

Inventor

Yoshinari Kumagai

Russell Blacher

Toshiyuki Yoneda

Original Assignee

Acologix Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-16

Filing date

2001-08-14

Publication date

2009-05-15

2001-08-14 Application filed by Acologix Inc filed Critical Acologix Inc

2009-05-15 Application granted granted Critical

2009-05-15 Publication of ATE430165T1 publication Critical patent/ATE430165T1/de

Links

102000006495 integrins Human genes 0.000 title abstract 2
108010044426 integrins Proteins 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
238000000034 method Methods 0.000 title 1
210000003205 muscle Anatomy 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
150000001413 amino acids Chemical class 0.000 abstract 2
102000005701 Calcium-Binding Proteins Human genes 0.000 abstract 1
108010045403 Calcium-Binding Proteins Proteins 0.000 abstract 1
229920002683 Glycosaminoglycan Polymers 0.000 abstract 1
102100026142 Matrix extracellular phosphoglycoprotein Human genes 0.000 abstract 1
101710184030 Matrix extracellular phosphoglycoprotein Proteins 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
239000002324 mouth wash Substances 0.000 abstract 1
229940051866 mouthwash Drugs 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
229940034610 toothpaste Drugs 0.000 abstract 1
239000000606 toothpaste Substances 0.000 abstract 1
230000002485 urinary effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4728—Calcium binding proteins, e.g. calmodulin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Diabetes (AREA)
Cell Biology (AREA)
Marine Sciences & Fisheries (AREA)
Obesity (AREA)
Oral & Maxillofacial Surgery (AREA)
Birds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Cosmetics (AREA)
Medicinal Preparation (AREA)

AT01965941T 2000-08-16 2001-08-14 Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten ATE430165T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US64103400A	2000-08-16	2000-08-16
US09/812,485 US6911425B2 (en)	2000-08-16	2001-03-19	Integrin binding motif containing peptides and methods of treating skeletal diseases
PCT/US2001/025542 WO2002014360A1 (en)	2000-08-16	2001-08-14	Integrin binding motif containing peptides and methods of treating skeletal diseases

Publications (1)

Publication Number	Publication Date
ATE430165T1 true ATE430165T1 (de)	2009-05-15

Family

ID=27093672

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01965941T ATE430165T1 (de)	2000-08-16	2001-08-14	Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten

Country Status (11)

Country	Link
US (5)	US6911425B2 (de)
EP (1)	EP1309616B1 (de)
JP (3)	JP4318246B2 (de)
CN (1)	CN100488980C (de)
AT (1)	ATE430165T1 (de)
AU (2)	AU8649101A (de)
CA (1)	CA2418716A1 (de)
DE (1)	DE60138552D1 (de)
ES (1)	ES2324153T3 (de)
MX (1)	MXPA03001394A (de)
WO (1)	WO2002014360A1 (de)

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TWI227734B (en) *	1998-05-18	2005-02-11	Univ London	A novel polypeptide hormone phosphatonin
DE60134864D1 (de) *	2000-08-16	2008-08-28	Acologix Inc	Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern
US6911425B2 (en) *	2000-08-16	2005-06-28	Acologix, Inc.	Integrin binding motif containing peptides and methods of treating skeletal diseases
AU2004294673B2 (en) *	2003-12-01	2010-05-20	Arla Foods Amba	Use of osteopontin in dental formulations
US20060193916A1 (en) *	2005-01-07	2006-08-31	Acologix, Inc.	Formulations of peptides for periodontal and dental treatments
EP1928491A4 (de) *	2005-07-18	2009-08-26	Acologix Inc	Proteinformulierung zur förderung der bildung von hartem gewebe
CN100366302C (zh) *	2006-09-14	2008-02-06	清华大学	一种用于骨修复的矿化多肽材料及其制备方法
US7888462B2 (en) *	2007-01-22	2011-02-15	Acologix, Inc.	Peptide composition and a method of promoting cartilage formation
JP5519121B2 (ja) *	2008-06-02	2014-06-11	学校法人東日本学園	新規ｒｇｄ含有ペプチドおよび象牙質再生剤、骨再生剤、歯周組織再生剤
SG186129A1 (en) *	2010-06-01	2013-01-30	Belle Aire Fragrances Inc	Oral odor control method and product
RU2503458C1 (ru) *	2012-08-27	2014-01-10	Сергей Васильевич Чуйкин	Способ местного лечения и профилактики основных стоматологических заболеваний у детей с хронической почечной недостаточностью с применением жевательного фитосубстрата
JP6692676B2 (ja) *	2016-04-12	2020-05-13	学校法人東日本学園	ネフロネクチンを含むう蝕治療剤
CN106943311A (zh) *	2017-04-07	2017-07-14	缪来耿	一种用于预防和或治疗牙周炎的牙膏及其制备方法
WO2018231793A1 (en)	2017-06-14	2018-12-20	Othrotrophix	Method of alleviating joint pain
US11963996B2 (en)	2018-10-24	2024-04-23	Orthotrophix, Inc.	Method of treating knee pain
CN109762069B (zh) *	2018-11-05	2022-01-14	广州领晟医疗科技有限公司	一种融合蛋白、其药物组合物及用途
US20200170939A1 (en)	2018-12-04	2020-06-04	Orthotrophix, Inc.	Method of treating osteoarthritis
CN111265652B (zh) *	2020-02-27	2023-06-27	广州领晟医疗科技有限公司	多肽在制备治疗缺血性脑血管疾病的药物中的应用
CN111358935B (zh) *	2020-02-27	2023-06-27	广州领晟医疗科技有限公司	多肽在制备抗肿瘤和/或抑制肿瘤转移药物中的用途及药物
CN111249446B (zh) *	2020-02-27	2023-06-27	广州领晟医疗科技有限公司	多肽及其盐的新用途
CN111569046B (zh) *	2020-04-14	2023-06-27	广州领晟医疗科技有限公司	多肽在制备治疗胰腺炎药物中的用途及含有其的药物
WO2022072156A1 (en)	2020-10-01	2022-04-07	Orthotrophix, Inc.	Hard tissue therapeutics

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US6673900B2 (en) *	1999-11-04	2004-01-06	University College London	Polypeptide hormone-phosphatonin
TWI227734B (en)	1998-05-18	2005-02-11	Univ London	A novel polypeptide hormone phosphatonin
US6045780A (en)	1998-06-22	2000-04-04	Shemberg Marketing Corporation	Toothpaste composition
AUPP893999A0 (en) *	1999-03-01	1999-03-25	Csl Limited	Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
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DE60134864D1 (de) *	2000-08-16	2008-08-28	Acologix Inc	Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern
US6911425B2 (en) *	2000-08-16	2005-06-28	Acologix, Inc.	Integrin binding motif containing peptides and methods of treating skeletal diseases

2001
- 2001-03-19 US US09/812,485 patent/US6911425B2/en not_active Expired - Lifetime
- 2001-08-14 EP EP01965941A patent/EP1309616B1/de not_active Expired - Lifetime
- 2001-08-14 CN CNB018157939A patent/CN100488980C/zh not_active Expired - Fee Related
- 2001-08-14 DE DE60138552T patent/DE60138552D1/de not_active Expired - Lifetime
- 2001-08-14 MX MXPA03001394A patent/MXPA03001394A/es active IP Right Grant
- 2001-08-14 AU AU8649101A patent/AU8649101A/xx active Pending
- 2001-08-14 JP JP2002519497A patent/JP4318246B2/ja not_active Expired - Fee Related
- 2001-08-14 CA CA002418716A patent/CA2418716A1/en not_active Abandoned
- 2001-08-14 WO PCT/US2001/025542 patent/WO2002014360A1/en not_active Ceased
- 2001-08-14 ES ES01965941T patent/ES2324153T3/es not_active Expired - Lifetime
- 2001-08-14 AT AT01965941T patent/ATE430165T1/de not_active IP Right Cessation
- 2001-08-14 AU AU2001286491A patent/AU2001286491B2/en not_active Ceased
2005
- 2005-01-24 US US11/042,492 patent/US7160862B2/en not_active Expired - Lifetime
2006
- 2006-09-13 US US11/531,583 patent/US20070014742A1/en not_active Abandoned
2007
- 2007-05-15 JP JP2007128730A patent/JP2007302673A/ja not_active Withdrawn
- 2007-10-26 US US11/925,411 patent/US20090042791A1/en not_active Abandoned
2008
- 2008-07-03 US US12/167,491 patent/US20090062201A1/en not_active Abandoned
2010
- 2010-11-11 JP JP2010252426A patent/JP2011032286A/ja active Pending

Also Published As

Publication number	Publication date
WO2002014360A1 (en)	2002-02-21
JP2007302673A (ja)	2007-11-22
US20070014742A1 (en)	2007-01-18
JP2011032286A (ja)	2011-02-17
EP1309616B1 (de)	2009-04-29
JP2004506654A (ja)	2004-03-04
AU2001286491B2 (en)	2006-04-27
CN1458935A (zh)	2003-11-26
DE60138552D1 (de)	2009-06-10
US20090062201A1 (en)	2009-03-05
EP1309616A4 (de)	2004-12-08
AU8649101A (en)	2002-02-25
US7160862B2 (en)	2007-01-09
US20090042791A1 (en)	2009-02-12
US6911425B2 (en)	2005-06-28
CN100488980C (zh)	2009-05-20
MXPA03001394A (es)	2004-12-13
JP4318246B2 (ja)	2009-08-19
ES2324153T3 (es)	2009-07-31
US20050163728A1 (en)	2005-07-28
US20020197267A1 (en)	2002-12-26
CA2418716A1 (en)	2002-02-21
EP1309616A1 (de)	2003-05-14

Legal Events

Date	Code	Title	Description
2009-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60138552D1 (de)	2009-06-10	Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten
CA2596597A1 (en)	2006-08-10	Method for stimulation collagen synthesis and/or kgf expression
MX361694B (es)	2018-12-10	Fragmentos de peptidos para inducir sintesis de proteinas de matriz extra-celular.
BR0309877A (pt)	2005-04-26	Peptìdeos estimuladores de tecido conectivo
DE60045524D1 (de)	2011-02-24	Ein Huhn GnRH-II Analog zur Verwendung in der Reduktion des Tumorzellwachstums
ATE450548T1 (de)	2009-12-15	Rgd-angereicherte gelatineähnliche proteine mit verstärkter zellbindung
CA2213533A1 (en)	1996-08-29	Resorbable extracellular matrix for reconstruction of cartilage tissue
WO2004073616A3 (en)	2004-11-25	Elastin digest compositions and methods utilizing same
EP1661909A4 (de)	2006-08-30	Biologisch nicht-abbaubares peptid, inhibitor des angiotensinumwandelnden enzyms, arzneimittel und funktionelles nahrungsmittel
AU3576597A (en)	1998-01-07	Endoderm, cardiac and neural inducing factors
MXPA02000465A (es)	2002-07-30	Derivados ciclopeptidicos como inhibidores de la integrina alfav beta6.
DK1313440T3 (da)	2008-11-03	Dentalprodukter indeholdende knoglevækstforögende peptider
BR0111506A (pt)	2003-06-24	Complexos de droga macromoleculares e composições contendo os mesmos
WO2002058589A3 (en)	2003-07-17	Agents and methods for promoting bone growth
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