ATE430194T1 - Endgruppenaktivierte polymere mit oligonucleotid- liganden - Google Patents
Endgruppenaktivierte polymere mit oligonucleotid- ligandenInfo
- Publication number
- ATE430194T1 ATE430194T1 AT02733793T AT02733793T ATE430194T1 AT E430194 T1 ATE430194 T1 AT E430194T1 AT 02733793 T AT02733793 T AT 02733793T AT 02733793 T AT02733793 T AT 02733793T AT E430194 T1 ATE430194 T1 AT E430194T1
- Authority
- AT
- Austria
- Prior art keywords
- copolymer
- oligonucleotides
- substrate
- group
- types
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 5
- 239000003446 ligand Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 5
- 229920001577 copolymer Polymers 0.000 abstract 4
- 239000000758 substrate Substances 0.000 abstract 4
- 230000000295 complement effect Effects 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
Landscapes
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26608101P | 2001-02-02 | 2001-02-02 | |
| PCT/US2002/003341 WO2002077159A2 (en) | 2001-02-02 | 2002-02-04 | End group activated polymers with oligonucleotide ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE430194T1 true ATE430194T1 (de) | 2009-05-15 |
Family
ID=23013089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02733793T ATE430194T1 (de) | 2001-02-02 | 2002-02-04 | Endgruppenaktivierte polymere mit oligonucleotid- liganden |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7645721B2 (de) |
| EP (1) | EP1363961B1 (de) |
| JP (1) | JP4328533B2 (de) |
| AT (1) | ATE430194T1 (de) |
| AU (1) | AU2002305924A1 (de) |
| CA (1) | CA2435894C (de) |
| DE (1) | DE60232135D1 (de) |
| WO (1) | WO2002077159A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004037310A2 (en) * | 2002-10-21 | 2004-05-06 | Allvivo, Inc. | Surface coating comprising bioactive compound |
| US7858108B2 (en) * | 2003-10-21 | 2010-12-28 | Richard Nagler | Elutable surface coating |
| SE0401033D0 (sv) * | 2004-04-20 | 2004-04-20 | Amersham Biosciences Ab | Device and method for protein analysis |
| WO2005118020A1 (en) * | 2004-04-21 | 2005-12-15 | Allvivo, Inc. | Surface coating comprising bioactive compound |
| US9295760B2 (en) | 2009-04-09 | 2016-03-29 | The University Of Queensland | Block copolymer blends |
| JP7378212B2 (ja) * | 2019-02-28 | 2023-11-13 | 浜松ホトニクス株式会社 | 細胞接着用組成物及び細胞接着用基材 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0636186B1 (de) | 1992-04-03 | 1998-11-25 | The Perkin-Elmer Corporation | Proben zusammensetzung und verfahren |
| US5470705A (en) * | 1992-04-03 | 1995-11-28 | Applied Biosystems, Inc. | Probe composition containing a binding domain and polymer chain and methods of use |
| US5516703A (en) | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
| US6284503B1 (en) | 1993-08-20 | 2001-09-04 | University Of Utah Research Foundation | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
| US6060246A (en) * | 1996-11-15 | 2000-05-09 | Avi Biopharma, Inc. | Reagent and method for isolation and detection of selected nucleic acid sequences |
| DE19741716A1 (de) * | 1997-09-22 | 1999-03-25 | Hoechst Ag | Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung |
| US6087452A (en) | 1998-06-02 | 2000-07-11 | University Of Utah | Metal-chelating surfacant |
| EP1210607A4 (de) * | 1999-08-13 | 2004-12-22 | Nanogen Inc | Mikroelektronische, molekulare deskriptor-feldvorrichtung, methoden, verfahren und formate zur kombinatorischen auswahl von intermolekularen ligandbindenden strukturen und zur überprüfung von medikamenten |
-
2002
- 2002-02-04 DE DE60232135T patent/DE60232135D1/de not_active Expired - Lifetime
- 2002-02-04 JP JP2002576602A patent/JP4328533B2/ja not_active Expired - Fee Related
- 2002-02-04 AT AT02733793T patent/ATE430194T1/de not_active IP Right Cessation
- 2002-02-04 CA CA2435894A patent/CA2435894C/en not_active Expired - Fee Related
- 2002-02-04 AU AU2002305924A patent/AU2002305924A1/en not_active Abandoned
- 2002-02-04 WO PCT/US2002/003341 patent/WO2002077159A2/en not_active Ceased
- 2002-02-04 US US10/470,296 patent/US7645721B2/en not_active Expired - Fee Related
- 2002-02-04 EP EP02733793A patent/EP1363961B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1363961A2 (de) | 2003-11-26 |
| CA2435894C (en) | 2014-05-13 |
| US20040219541A1 (en) | 2004-11-04 |
| US7645721B2 (en) | 2010-01-12 |
| DE60232135D1 (de) | 2009-06-10 |
| WO2002077159A2 (en) | 2002-10-03 |
| JP2004524038A (ja) | 2004-08-12 |
| AU2002305924A1 (en) | 2002-10-08 |
| EP1363961A4 (de) | 2004-12-22 |
| EP1363961B1 (de) | 2009-04-29 |
| WO2002077159A3 (en) | 2002-11-14 |
| JP4328533B2 (ja) | 2009-09-09 |
| CA2435894A1 (en) | 2002-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |