ATE431166T1 - System zum transfer von flüssigkeit im innenohr und zur diagnose - Google Patents

System zum transfer von flüssigkeit im innenohr und zur diagnose

Info

Publication number
ATE431166T1
ATE431166T1 AT98929016T AT98929016T ATE431166T1 AT E431166 T1 ATE431166 T1 AT E431166T1 AT 98929016 T AT98929016 T AT 98929016T AT 98929016 T AT98929016 T AT 98929016T AT E431166 T1 ATE431166 T1 AT E431166T1
Authority
AT
Austria
Prior art keywords
cover member
fluid
round window
fluids
niche
Prior art date
Application number
AT98929016T
Other languages
English (en)
Inventor
Irving Arenberg
Michael Arenberg
Original Assignee
Durect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Durect Corp filed Critical Durect Corp
Application granted granted Critical
Publication of ATE431166T1 publication Critical patent/ATE431166T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • A61F11/20—Ear surgery
    • A61F11/202—Surgical middle-ear ventilation or drainage, e.g. permanent; Implants therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00787—Surgery of the ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A61M1/85—Drainage tubes; Aspiration tips with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0662—Ears
    • A61M2210/0668—Middle ear

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Endoscopes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AT98929016T 1997-06-13 1998-06-11 System zum transfer von flüssigkeit im innenohr und zur diagnose ATE431166T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/874,208 US6045528A (en) 1997-06-13 1997-06-13 Inner ear fluid transfer and diagnostic system
PCT/US1998/012194 WO1998056434A1 (en) 1997-06-13 1998-06-11 Inner ear fluid transfer and diagnostic system

Publications (1)

Publication Number Publication Date
ATE431166T1 true ATE431166T1 (de) 2009-05-15

Family

ID=25363233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98929016T ATE431166T1 (de) 1997-06-13 1998-06-11 System zum transfer von flüssigkeit im innenohr und zur diagnose

Country Status (8)

Country Link
US (1) US6045528A (de)
EP (1) EP0989868B1 (de)
AT (1) ATE431166T1 (de)
AU (1) AU737470B2 (de)
CA (1) CA2292408C (de)
DE (1) DE69840829D1 (de)
ES (1) ES2326100T3 (de)
WO (1) WO1998056434A1 (de)

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440102B1 (en) * 1998-07-23 2002-08-27 Durect Corporation Fluid transfer and diagnostic system for treating the inner ear
US8197461B1 (en) 1998-12-04 2012-06-12 Durect Corporation Controlled release system for delivering therapeutic agents into the inner ear
US6629922B1 (en) * 1999-10-29 2003-10-07 Soundport Corporation Flextensional output actuators for surgically implantable hearing aids
SE0100158D0 (sv) * 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
US6770080B2 (en) * 2001-04-26 2004-08-03 Fenestra Medical, Inc. Mechanically registered videoscopic myringotomy/tympanostomy tube placement system
US20050222066A1 (en) * 2001-05-18 2005-10-06 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US20070270579A1 (en) * 2001-05-18 2007-11-22 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
US7517864B2 (en) * 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US20080161256A1 (en) * 2001-05-18 2008-07-03 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US20060241075A1 (en) * 2001-05-18 2006-10-26 Sirna Therapeutics, Inc. RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
US20070042983A1 (en) * 2001-05-18 2007-02-22 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
US20050282188A1 (en) * 2001-05-18 2005-12-22 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
ES2271278T3 (es) * 2001-06-18 2007-04-16 Durect Corporation Dispositivo para administrar microdosis de agentes en el oido.
US6648873B2 (en) 2001-09-21 2003-11-18 Durect Corp. Aural catheter system including anchor balloon and balloon inflation device
EP2226043B1 (de) * 2001-10-24 2014-12-31 MED-EL Elektromedizinische Geräte GmbH Implantierbare Flussigkeits-Verabreichungs-Vorrichtung und implantierbare Elektrode
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US9181551B2 (en) 2002-02-20 2015-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US20030229333A1 (en) * 2002-02-22 2003-12-11 Control Delivery Systems, Inc. Methods for treating otic disorders
US20150150455A9 (en) * 2002-07-03 2015-06-04 Epley Research, Llc Stimulus-evoked vestibular evaluation system, method and apparatus
US20060009739A1 (en) * 2002-09-06 2006-01-12 Durect Corporation Implantable flow regulator with failsafe mode and reserve drug supply
US6694190B1 (en) * 2002-11-05 2004-02-17 Advanced Lochlear Systems, Inc. Apparatus and method for treating strial hearing loss
US7892180B2 (en) * 2002-11-18 2011-02-22 Epley Research Llc Head-stabilized medical apparatus, system and methodology
DE10305349A1 (de) 2003-02-10 2004-08-26 Cell Center Cologne Gmbh Innenohr-Steckverbindung
US7351246B2 (en) * 2004-01-20 2008-04-01 Epley John M Minimally invasive, sustained, intra-tympanic drug delivery system
US20060063802A1 (en) * 2004-03-29 2006-03-23 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US8268866B2 (en) 2004-03-29 2012-09-18 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US9072662B2 (en) 2004-03-29 2015-07-07 Auris Medical Ag Methods for the treatment of tinnitus induced by cochlear excitotoxicity
EP1744660A4 (de) * 2004-05-04 2010-07-07 Epley Research L L C Stabilisiertes medizinisches gerät; system und methodik
US20120253267A1 (en) * 2004-05-24 2012-10-04 Reed Don C Combined otic and medication dispenser and method for treating otic infections
US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US7668325B2 (en) * 2005-05-03 2010-02-23 Earlens Corporation Hearing system having an open chamber for housing components and reducing the occlusion effect
US8295523B2 (en) * 2007-10-04 2012-10-23 SoundBeam LLC Energy delivery and microphone placement methods for improved comfort in an open canal hearing aid
US7867160B2 (en) * 2004-10-12 2011-01-11 Earlens Corporation Systems and methods for photo-mechanical hearing transduction
US8401212B2 (en) 2007-10-12 2013-03-19 Earlens Corporation Multifunction system and method for integrated hearing and communication with noise cancellation and feedback management
TR200403298A1 (tr) * 2004-12-03 2006-02-21 Kutluhan Ahmet Mastoid antral ventilasyon tüpü
JP2008537684A (ja) * 2005-01-24 2008-09-25 ニューロシステック コーポレイション 内耳およびその他の組織へ治療薬および／またはその他の薬剤を送達するための装置および方法
DE102005004343A1 (de) * 2005-01-25 2006-08-10 Eberhard-Karls-Universität Tübingen Universitätsklinikum Behandlung von Phantomphänomenen
US20110077579A1 (en) * 2005-03-24 2011-03-31 Harrison William V Cochlear implant with localized fluid transport
US8956333B2 (en) 2005-04-22 2015-02-17 Alternamedics Llc Medication delivery device
US20060253087A1 (en) * 2005-04-22 2006-11-09 Aner Vlodaver Medication delivery device
US8309057B2 (en) * 2005-06-10 2012-11-13 The Invention Science Fund I, Llc Methods for elevating neurotrophic agents
US20090176725A1 (en) * 2005-08-17 2009-07-09 Sirna Therapeutics Inc. Chemically modified short interfering nucleic acid molecules that mediate rna interference
CA2620374C (en) * 2005-09-28 2012-12-11 Thomas Meyer Pharmaceutical compositions for the treatment of inner ear disorders
US8267905B2 (en) * 2006-05-01 2012-09-18 Neurosystec Corporation Apparatus and method for delivery of therapeutic and other types of agents
US7803148B2 (en) * 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
US20080152694A1 (en) * 2006-07-20 2008-06-26 Neurosystec Corporation Devices, Systems and Methods for Ophthalmic Drug Delivery
WO2008016602A2 (en) * 2006-07-31 2008-02-07 Neurosystec Corporation Free base gacyclidine nanoparticles
US20080065002A1 (en) * 2006-09-07 2008-03-13 Neurosystec Corporation Catheter for Localized Drug Delivery and/or Electrical Stimulation
US8249700B2 (en) 2007-04-19 2012-08-21 Acclarent, Inc. System and method for the simultaneous bilateral integrated tympanic drug delivery and guided treatment of target tissues within the ears
US8192420B2 (en) * 2007-12-20 2012-06-05 Acclarent, Inc. Iontophoresis methods
US8396239B2 (en) 2008-06-17 2013-03-12 Earlens Corporation Optical electro-mechanical hearing devices with combined power and signal architectures
KR101568451B1 (ko) 2008-06-17 2015-11-11 이어렌즈 코포레이션 결합된 전력 및 신호 구조를 갖는 광학 전기기계 듣기 장치
WO2009155358A1 (en) 2008-06-17 2009-12-23 Earlens Corporation Optical electro-mechanical hearing devices with separate power and signal components
WO2010011605A2 (en) 2008-07-21 2010-01-28 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
US8318817B2 (en) 2008-07-21 2012-11-27 Otonomy, Inc. Controlled release antimicrobial compositions and methods for the treatment of otic disorders
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
US8452392B2 (en) * 2008-07-31 2013-05-28 Acclarent, Inc. Systems and methods for anesthetizing ear tissue
US8840602B2 (en) 2008-07-31 2014-09-23 Acclarent, Inc. Systems and methods for anesthetizing ear tissue
CN102301747B (zh) 2008-09-22 2016-09-07 依耳乐恩斯公司 用于听觉的平衡电枢装置和方法
US9078783B2 (en) 2008-12-24 2015-07-14 Acclarent, Inc. Silent effusion removal
DK2438768T3 (en) * 2009-06-05 2016-06-06 Earlens Corp Optically coupled acoustically mellemøreimplantatindretning
US9544700B2 (en) * 2009-06-15 2017-01-10 Earlens Corporation Optically coupled active ossicular replacement prosthesis
WO2010148345A2 (en) 2009-06-18 2010-12-23 SoundBeam LLC Eardrum implantable devices for hearing systems and methods
AU2010263045A1 (en) * 2009-06-18 2012-02-09 Earlens Corporation Optically coupled cochlear implant systems and methods
CN102598715B (zh) 2009-06-22 2015-08-05 伊尔莱茵斯公司 光耦合骨传导设备、系统及方法
US10555100B2 (en) * 2009-06-22 2020-02-04 Earlens Corporation Round window coupled hearing systems and methods
WO2010151636A2 (en) 2009-06-24 2010-12-29 SoundBeam LLC Optical cochlear stimulation devices and methods
WO2010151647A2 (en) 2009-06-24 2010-12-29 SoundBeam LLC Optically coupled cochlear actuator systems and methods
EP3649995A1 (de) * 2009-07-15 2020-05-13 Tusker Medical, Inc. System zur freisetzung einer trommelfelldruckausgleichsröhre
US9770366B2 (en) 2009-07-15 2017-09-26 Tusker Medical, Inc. Tympanic membrane pressure equalization tube delivery system
US9539146B2 (en) 2009-07-15 2017-01-10 Tusker Medical, Inc. Trigger assembly for tympanostomy tube delivery device
WO2011115936A1 (en) * 2010-03-15 2011-09-22 Lev Rosenblum Device and method for delivering medicine into the tympanic cavity, with sliding assist
USD640374S1 (en) 2010-07-15 2011-06-21 Acclarent, Inc. Tube delivery device
WO2012058210A1 (en) 2010-10-29 2012-05-03 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
EP3758394A1 (de) 2010-12-20 2020-12-30 Earlens Corporation Anatomisch angepasstes gehörgangs-hörgerät
WO2012106501A1 (en) * 2011-02-02 2012-08-09 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
JP2014525795A (ja) 2011-07-25 2014-10-02 アクラレント インコーポレイテッド 個人化可能鼓膜麻酔システム及び方法
ES2862673T3 (es) 2011-12-12 2021-10-07 Zilentin AG Tratamiento del tinnitus mediante la modulación del cotransportador de cloruro NKCC1 en el sistema auditivo
US9370510B2 (en) 2012-02-24 2016-06-21 Fate Therapeutics, Inc. Small molecule compounds to treat hearing loss
US9011363B2 (en) * 2012-04-10 2015-04-21 Acclarent, Inc. Tympanic membrane pressure equalization tube
US9364648B2 (en) 2012-05-30 2016-06-14 Tusker Medical, Inc. Adhesive earplugs useful for sealing the ear canal
US10687982B2 (en) 2012-07-05 2020-06-23 Domestic Legacy Limited Partnership One-step tympanostomy tube and method for inserting same
US9907699B2 (en) 2012-07-05 2018-03-06 Domestic Legacy Limited Partnership One step tympanostomy tube and method of inserting same
EP2931196A4 (de) * 2012-12-14 2016-07-13 Univ Columbia System und verfahren zur lokalen verabreichung eines therapeutikums in das innenohr
US10821276B2 (en) * 2012-12-14 2020-11-03 The Trustees Of Columbia University In The City Of New York System and method to locally deliver therapeutic agent to inner ear
BR112015023261A2 (pt) 2013-03-14 2017-07-18 Massachusetts Inst Technology composições e métodos para expansão e cultura de células-tronco epiteliais
US10130808B2 (en) 2013-03-14 2018-11-20 Tusker Medical, Inc. System and method for providing iontophoresis at tympanic membrane
US9320652B2 (en) 2013-03-14 2016-04-26 Tusker Medical, Inc. Features to improve and sense tympanic membrane apposition by tympanostomy tube delivery instrument
US9681891B2 (en) 2013-03-14 2017-06-20 Tusker Medical, Inc. Tympanostomy tube delivery device with cutting dilator
CN105682742A (zh) 2013-08-27 2016-06-15 奥德纳米有限公司 小儿耳部病症的治疗
US10034103B2 (en) 2014-03-18 2018-07-24 Earlens Corporation High fidelity and reduced feedback contact hearing apparatus and methods
CN106794144B (zh) 2014-07-03 2020-07-17 奥德纳米有限公司 环丙沙星组合物的灭菌
WO2016011044A1 (en) 2014-07-14 2016-01-21 Earlens Corporation Sliding bias and peak limiting for optical hearing devices
US20160038341A1 (en) * 2014-08-08 2016-02-11 Acclarent, Inc. Tympanostomy tube delivery device with elastomeric brake
US10195086B2 (en) 2014-08-11 2019-02-05 Tusker Medical, Inc. Tympanostomy tube delivery device with rotatable
US9833360B2 (en) 2014-08-12 2017-12-05 Tusker Medical, Inc. Tympanostomy tube delivery device with replaceable shaft portion
US9833359B2 (en) 2014-08-12 2017-12-05 Tusker Medical, Inc. Tympanostomy tube delivery device with cutter force clutch
CN107073042A (zh) 2014-09-03 2017-08-18 布里格海姆妇女医院公司 用于产生内耳毛细胞来治疗听力损失的组合物、系统和方法
US9924276B2 (en) 2014-11-26 2018-03-20 Earlens Corporation Adjustable venting for hearing instruments
US10016304B2 (en) 2015-07-16 2018-07-10 Tusker Medical, Inc. Earplug assembly for iontophoresis system
WO2017059218A1 (en) 2015-10-02 2017-04-06 Earlens Corporation Wearable customized ear canal apparatus
WO2017100576A1 (en) 2015-12-11 2017-06-15 Otonomy, Inc. Ciprofloxacin otic composition and kits and method for using same
US11350226B2 (en) 2015-12-30 2022-05-31 Earlens Corporation Charging protocol for rechargeable hearing systems
US10178483B2 (en) 2015-12-30 2019-01-08 Earlens Corporation Light based hearing systems, apparatus, and methods
US10492010B2 (en) 2015-12-30 2019-11-26 Earlens Corporations Damping in contact hearing systems
CA3010610A1 (en) 2016-01-08 2017-07-13 The Brigham And Women's Hospital, Inc. Production of differentiated enteroendocrine cells and insulin producing cells
US11260130B2 (en) 2016-03-02 2022-03-01 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV
US9968615B2 (en) 2016-03-02 2018-05-15 Frequency Therapeutics, Inc. Methods for controlled proliferation of stem cells / generating inner ear hair cells using 3-(pyridin-2-yl)-1H-indol-2-ol based compounds
US9913848B2 (en) 2016-03-02 2018-03-13 Frequency Therapeutics, Inc. Methods for controlled proliferation of stem cells / generating inner ear hair cells using 1,2,3,4-tetrahydro-[1,4]diazepino[6,7, 1-hi]indolyl based compounds
US10201540B2 (en) 2016-03-02 2019-02-12 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I
US10213511B2 (en) 2016-03-02 2019-02-26 Frequency Therapeutics, Inc. Thermoreversible compositions for administration of therapeutic agents
US9913835B2 (en) 2016-03-02 2018-03-13 Frequency Therapeutics, Inc. Methods for controlled proliferation of stem cells / generating inner ear hair cells using N-(alkylcarbamoyl)-1H-pyrazol-4-yl)-nicotinamide based compounds
US10016507B2 (en) 2016-03-02 2018-07-10 Frequency Therapeutics, Inc. Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III
US11213430B2 (en) 2016-05-26 2022-01-04 Cochlear Limited Inner ear plug
EP3478269A4 (de) 2016-06-29 2020-04-08 Otonomy, Inc. Triclyceridformulierungen für das ohr und verwendungen davon
EP3510796B1 (de) 2016-09-09 2026-01-14 Earlens Corporation Kontakthörsysteme, vorrichtung und verfahren
EP3512513A4 (de) 2016-09-16 2020-04-15 Otonomy, Inc. Gelformulierungen für das ohr zur behandlung von otitis externa
WO2018093733A1 (en) 2016-11-15 2018-05-24 Earlens Corporation Improved impression procedure
AU2017386417B2 (en) 2016-12-30 2022-07-14 Frequency Therapeutics, Inc. 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells
US11844919B2 (en) 2018-01-03 2023-12-19 The Trustees Of Columbia University In The City Of New York Microneedle for local delivery of therapeutic agent
EP3740111A1 (de) 2018-01-16 2020-11-25 Tusker Medical, Inc. Visualisierungsvorrichtung und verfahren für otologische vorgänge
WO2019173470A1 (en) 2018-03-07 2019-09-12 Earlens Corporation Contact hearing device and retention structure materials
WO2019199680A1 (en) 2018-04-09 2019-10-17 Earlens Corporation Dynamic filter
WO2020037323A1 (en) 2018-08-17 2020-02-20 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by upregulating jag-1
WO2020037326A1 (en) 2018-08-17 2020-02-20 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by downregulating foxo
US20230058189A1 (en) 2019-02-08 2023-02-23 Frequency Therapeutics, Inc. Quinolin-4-one and 4(1h)-cinnolinone compounds and methods of using same
WO2020163812A1 (en) 2019-02-08 2020-08-13 Frequency Therapeutics, Inc. Valproic acid compounds and wnt agonists for treating ear disorders
ES1227773Y (es) * 2019-02-22 2019-06-26 Veciana Carlos Magrina Dispositivo aplicador
US12390098B2 (en) 2019-07-17 2025-08-19 Tusker Medical, Inc. Systems, devices, and methods for visualization during medical procedures
US11890438B1 (en) 2019-09-12 2024-02-06 Cochlear Limited Therapeutic substance delivery
CN115426991A (zh) 2020-01-24 2022-12-02 斯皮拉尔诊疗有限公司 用于治疗耳部疾病的装置、系统和方法
EP4183380A1 (de) * 2021-11-22 2023-05-24 Medizinische Hochschule Hannover Patientenspezifisches, arzneimittelfreisetzendes, komprimierbares implantat mit integriertem handgriff zum einsetzen in eine körperhöhle und verfahren zu seiner herstellung

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE850341C (de) * 1950-04-15 1952-09-25 Gazzoni & Co A Vorrichtung zum Benetzen des aeusseren Gehoerganges mit einer schmerzstillenden Fluessigkeit
GB1204117A (en) * 1966-09-08 1970-09-03 Syntex Corp Devices and methods for administering pharmaceutical preparations
US4034759A (en) * 1975-08-27 1977-07-12 Xomed, Inc. Moisture-expandable prosthesis
US4159719A (en) * 1977-05-09 1979-07-03 Xomed, Inc. Moisture-expandable ear wick
US4175563A (en) * 1977-10-05 1979-11-27 Arenberg Irving K Biological drainage shunt
US4244377A (en) * 1978-10-19 1981-01-13 Grams Guenter A Ear probe for use in closed-loop caloric irrigation
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
US4320758A (en) * 1979-05-07 1982-03-23 Alza Corporation Osmotically driven fluid dispenser
US4297748A (en) * 1980-01-02 1981-11-03 Moloy Peter J Middle ear balloon
US4419092A (en) * 1981-11-06 1983-12-06 Motion Control, Inc. Iontophoretic electrode structure
FR2556586B1 (fr) * 1983-12-20 1988-10-14 Biotrol Sa Lab Dispositif pour l'ecoulement de l'urine des urostomies
NO165378C (no) * 1985-11-22 1991-02-06 Ellingsen O & Co Medikamentavgivende innretning for implantering i menneskekroppen.
US5350395A (en) * 1986-04-15 1994-09-27 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
EP0266474B1 (de) * 1986-11-07 1993-03-31 DENSERT, Barbara Einrichtung zum Behandeln der Menièreschen Krankheit
US4888017A (en) * 1987-07-15 1989-12-19 The Cleveland Clinic Foundation Apparatus of controlling eustachian tube function
SE8703694L (sv) * 1987-09-25 1989-03-26 Barbara Densert Saett att lufta mellanoerat medelst en insaettbar ventilationstub, ventilationstub foer utfoerande av saettet jaemte anvaendning av en dylik ventilationstub
JP2683750B2 (ja) * 1988-06-06 1997-12-03 住友電気工業株式会社 カテーテル用バルーン
US4874368A (en) * 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
US4968297A (en) * 1989-05-09 1990-11-06 Iomec, Inc. Iontophoretic electrode with solution containment system
KR0141688B1 (ko) * 1989-05-24 1998-06-15 스까다 쇼오에이 액체형 약제를 연속적으로 주입하기 위한 기구를 가진 주입기
US5281287A (en) * 1989-07-21 1994-01-25 Iomed, Inc. Method of making a hydratable bioelectrode
US5171216A (en) * 1989-08-28 1992-12-15 Thermedics, Inc. Multi-lumen catheter coupling
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
DE69110467T2 (de) * 1990-06-15 1996-02-01 Cortrak Medical Inc Vorrichtung zur abgabe von medikamenten.
US5176654B1 (en) * 1990-12-07 1999-12-07 Simeon B Schreiber Method and apparatus for otologic administration of medicament
WO1992011895A1 (en) * 1990-12-28 1992-07-23 Boston Scientific Corporation Balloon drug delivery system
US5364343A (en) * 1991-03-06 1994-11-15 D.D. S.R.L. Irrigation device for use in ear canals for therapeutic or hygienic purposes
US5304134A (en) * 1992-01-17 1994-04-19 Danforth Biomedical, Inc. Lubricious yet bondable catheter channel sleeve for over-the-wire catheters
US5419312A (en) * 1993-04-20 1995-05-30 Wildflower Communications, Inc. Multi-function endoscope apparatus
US5417657A (en) * 1993-10-06 1995-05-23 Hauer; Carolyn No-sepsis urinary drainage catheter
US5421818A (en) * 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
DE4408108A1 (de) * 1994-03-10 1995-09-14 Bavaria Med Tech Katheter zur Injektion eines Fluid bzw. eines Arneimittelns
US5776111A (en) * 1996-11-07 1998-07-07 Medical Components, Inc. Multiple catheter assembly

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WO1998056434A1 (en) 1998-12-17
ES2326100T3 (es) 2009-09-30
CA2292408A1 (en) 1998-12-17
EP0989868B1 (de) 2009-05-13
CA2292408C (en) 2009-08-04
EP0989868A4 (de) 2002-02-27
DE69840829D1 (de) 2009-06-25
EP0989868A1 (de) 2000-04-05
AU737470B2 (en) 2001-08-23
AU8068098A (en) 1998-12-30
US6045528A (en) 2000-04-04

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