ATE431400T1 - Chirurgische vorrichtung zur haut-therapie und zum testen - Google Patents

Chirurgische vorrichtung zur haut-therapie und zum testen

Info

Publication number
ATE431400T1
ATE431400T1 AT03713880T AT03713880T ATE431400T1 AT E431400 T1 ATE431400 T1 AT E431400T1 AT 03713880 T AT03713880 T AT 03713880T AT 03713880 T AT03713880 T AT 03713880T AT E431400 T1 ATE431400 T1 AT E431400T1
Authority
AT
Austria
Prior art keywords
matrix
testing
surgical device
cells
cultured
Prior art date
Application number
AT03713880T
Other languages
English (en)
Inventor
Steven Boyce
Original Assignee
Univ Cincinnati
Shriners Hospitals Children
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cincinnati, Shriners Hospitals Children filed Critical Univ Cincinnati
Application granted granted Critical
Publication of ATE431400T1 publication Critical patent/ATE431400T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
AT03713880T 2002-03-06 2003-03-03 Chirurgische vorrichtung zur haut-therapie und zum testen ATE431400T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/092,237 US7741116B2 (en) 2002-03-06 2002-03-06 Surgical device for skin therapy or testing
PCT/US2003/006584 WO2003076604A2 (en) 2002-03-06 2003-03-03 Surgical device for skin therapy or testing

Publications (1)

Publication Number Publication Date
ATE431400T1 true ATE431400T1 (de) 2009-05-15

Family

ID=27804165

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03713880T ATE431400T1 (de) 2002-03-06 2003-03-03 Chirurgische vorrichtung zur haut-therapie und zum testen

Country Status (10)

Country Link
US (4) US7741116B2 (de)
EP (3) EP2302035B1 (de)
JP (3) JP4555576B2 (de)
AT (1) ATE431400T1 (de)
AU (1) AU2003217907A1 (de)
CA (1) CA2478107C (de)
DE (1) DE60327603D1 (de)
DK (1) DK1483373T3 (de)
ES (1) ES2326873T3 (de)
WO (1) WO2003076604A2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3372845B2 (ja) 1997-10-23 2003-02-04 株式会社フジクラ 光コネクタ
US7741116B2 (en) * 2002-03-06 2010-06-22 University Of Cincinnati Surgical device for skin therapy or testing
JP2005270477A (ja) * 2004-03-26 2005-10-06 Kazutaka Soejima 細胞含有人工真皮及びその調製方法
DE102004039537A1 (de) * 2004-08-13 2006-02-23 Phenion Gmbh & Co. Kg Vernetzte Kollagenmatrix zur Herstellung eines Hautäquivalentes
JP4951868B2 (ja) * 2005-03-18 2012-06-13 凸版印刷株式会社 薄膜トランジスタの製造方法
US9259445B2 (en) 2006-06-07 2016-02-16 Universidad Tecnica Federico Santa Maria Integrated implant system (IIS) biocompatible, biodegradable and bioactive, comprising a biocompatible sterile porous polymeric matrix and a gel, integrating in situ the tridimensional matrix structure
EP2152359A2 (de) 2007-05-25 2010-02-17 Compex Medical S.A. Elektrodenset für wundheilung
WO2009020650A2 (en) * 2007-08-08 2009-02-12 Pervasis Therapeutics, Inc. Materials and methods for treating and managing wounds and the effects of trauma
US9535056B2 (en) * 2008-01-10 2017-01-03 L'oreal Immune system modeling devices and methods
DE102009022351A1 (de) * 2009-05-15 2010-11-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Modulares Produktionssystem zur automatischen Herstellung von dreidimensionalen Gewebestrukturen
DE102010023156B4 (de) * 2010-06-02 2012-07-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. In vitro-Testsystem für virale Infektionen
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
ITPD20120390A1 (it) * 2012-12-19 2014-06-20 Univ Degli Studi Trieste Dispositivo comprendente una matrice biocompatibile e cellule endoteliali impiegabile nel trattamento di lesioni cutanee
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10772767B2 (en) 2013-06-28 2020-09-15 3M Innovative Properties Company Fibrin-coated wound dressing
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
EP3199622A4 (de) * 2014-09-23 2018-08-08 The University of Tokyo Dreidimensionales künstliches gewebe, verfahren zur herstellung davon, vorrichtung zur perfusion des dreidimensionalen künstlichen gewebes und arzneimittelbewertungsverfahren mit dreidimensionalem künstlichem gewebe
CN104548209B (zh) * 2015-02-03 2017-01-25 苏州磐升生物技术有限公司 一种组织工程表皮及其制备方法
CN104667352B (zh) * 2015-02-03 2016-11-09 济南磐升生物技术有限公司 一种带有真皮细胞的组织工程表皮的制备方法
EP3072535B1 (de) * 2015-03-26 2017-03-01 Université de Bordeaux Verfahren zur rekonstruktion von haut
JP2018518190A (ja) * 2015-06-25 2018-07-12 オークランド ユニサービシズ リミテッド 組織を培養する装置及び方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP6933855B2 (ja) * 2016-01-20 2021-09-08 国立大学法人 東京大学 人工皮膚組織の製造方法、人工皮膚組織灌流デバイス、人工皮膚組織を用いた薬剤評価方法
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
KR101908030B1 (ko) 2016-06-17 2018-10-15 울산대학교 산학협력단 상처 또는 궤양치료를 위한 3차원 세포시트 및 이의 제조방법
KR102874705B1 (ko) * 2017-12-07 2025-10-23 웨이크 포리스트 유니버시티 헬스 사이언시즈 다층 피부 구조체 및 그의 제조 및 사용 방법
JP6990139B2 (ja) * 2018-03-30 2022-02-03 株式会社 ジャパン・ティッシュ・エンジニアリング 移植材料の製造方法
IT201800010390A1 (it) 2018-11-16 2020-05-16 Diego Furlan Dispositivo medico monouso per la medicazione di lesioni della pelle di un paziente e relativi procedimenti di preparazione e utilizzazione
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
EP3875124A1 (de) * 2020-03-02 2021-09-08 Urgo Recherche Innovation Et Developpement Verfahren zur erzeugung eines prävaskularisierten dermo-epidermischen gewebes
US20240042095A1 (en) * 2020-12-21 2024-02-08 L&C Bio Co., Ltd. Composition for treating wound comprising dermal tissue-derived extracellular matrix and method for preparing same
CN113201481B (zh) * 2021-04-19 2023-10-13 清华大学深圳国际研究生院 皮肤微球及其制备方法和应用

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458678A (en) 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4673649A (en) 1983-07-15 1987-06-16 University Patents, Inc. Process and defined medium for growth of human epidermal keratinocyte cells
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
JPS62246371A (ja) * 1986-04-19 1987-10-27 株式会社　高研 人工皮膚及びその製造方法
JP3050879B2 (ja) 1987-04-28 2000-06-12 ザ・リージエント・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア 複合皮膚代用品の調製方法及び装置
US5273900A (en) 1987-04-28 1993-12-28 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
US5976878A (en) 1987-04-28 1999-11-02 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
GB8907493D0 (en) 1989-04-03 1989-05-17 Crespigny Alexander J D Region selection in nuclear magnetic resonance inspection
IL94611A (en) * 1989-06-05 1994-12-29 Organogenesis Inc Medium for cell cultures containing insulin or growth factor similar to insulin, transferrin or iron ion, triiodothyronine or thyroxine and method of use
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
RU2135191C1 (ru) 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор
ZA922947B (en) * 1991-04-23 1993-01-27 Regeneron Pharma Assay systems for neurotrophin activity
JPH05317406A (ja) 1992-05-20 1993-12-03 Terumo Corp 人工皮膚
US5578314A (en) 1992-05-29 1996-11-26 The Regents Of The University Of California Multiple layer alginate coatings of biological tissue for transplantation
CA2119064A1 (en) 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
US5891558A (en) 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
JP3547209B2 (ja) * 1995-03-08 2004-07-28 日本トムソン株式会社 直動転がり案内ユニット
JP3554412B2 (ja) * 1995-08-07 2004-08-18 株式会社メニコン 培養皮膚用基材、培養皮膚およびその製造法
JP3377354B2 (ja) * 1995-12-25 2003-02-17 株式会社メニコン 人工皮膚
CA2253724A1 (en) 1996-04-26 1997-11-06 Case Western Reserve University Skin regeneration using mesenchymal stem cells
FI107625B (fi) 1996-04-29 2001-09-14 Metso Paper Inc Menetelmä paperirainan kalanteroinnissa ja menetelmää soveltava kalanteri
JPH1043213A (ja) * 1996-08-07 1998-02-17 Menicon Co Ltd 培養皮膚の製造法、該製造法に用いる支持体および容器、ならびに該製造法によりえられる培養皮膚用基材および培養皮膚
FI104089B1 (fi) 1996-11-15 1999-11-15 Borealis As Prosessi propeenin homo- tai kopolymeerien valmistamiseksi
EP1062322A2 (de) 1998-02-24 2000-12-27 Advanced Tissue Sciences, Inc. Lebender chimärer hautersatz
US20010048917A1 (en) * 1998-03-09 2001-12-06 Warren Hoeffler Skin equivalent and methods of forming and using same
JP2000125855A (ja) 1998-10-21 2000-05-09 Gunze Ltd 人工皮膚
JP2002529071A (ja) * 1998-11-09 2002-09-10 コンソルツィオ・ペール・ラ・ジェスティオーネ・デル・チェントロ・ディ・ビオテクノロジー・アヴァンツァテ 軟骨細胞様細胞のための無血清培地
JP4214434B2 (ja) * 1998-11-12 2009-01-28 東洋紡績株式会社 培養皮膚、その製造方法及び用途
US6733530B1 (en) * 1999-08-02 2004-05-11 Eric Sun-Yin Chan Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin
JP4074043B2 (ja) * 2000-03-27 2008-04-09 株式会社資生堂 皮膚基底膜形成促進剤、人工皮膚形成促進剤及び人工皮膚の製造方法
JP4751005B2 (ja) 2000-05-31 2011-08-17 フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー．ファオ． 三次元皮膚モデル
CN1363398A (zh) 2002-01-16 2002-08-14 吉林大学 以壳多糖或其衍生物为基质网架的复层人工皮肤
US7741116B2 (en) * 2002-03-06 2010-06-22 University Of Cincinnati Surgical device for skin therapy or testing
US9184902B2 (en) 2012-04-25 2015-11-10 Nec Laboratories America, Inc. Interference cancellation for full-duplex communications

Also Published As

Publication number Publication date
EP1483373B1 (de) 2009-05-13
WO2003076604A3 (en) 2004-03-04
JP2005518910A (ja) 2005-06-30
JP5535446B2 (ja) 2014-07-02
JP5689023B2 (ja) 2015-03-25
JP2011172592A (ja) 2011-09-08
ES2326873T3 (es) 2009-10-21
US9089417B2 (en) 2015-07-28
EP2302035B1 (de) 2016-05-11
US20130259919A1 (en) 2013-10-03
DK1483373T3 (da) 2009-09-07
AU2003217907A1 (en) 2003-09-22
EP2302035A2 (de) 2011-03-30
US20140287020A1 (en) 2014-09-25
EP1483373A2 (de) 2004-12-08
DE60327603D1 (de) 2009-06-25
WO2003076604A2 (en) 2003-09-18
CA2478107A1 (en) 2003-09-18
US7741116B2 (en) 2010-06-22
US20030170892A1 (en) 2003-09-11
US8450108B2 (en) 2013-05-28
HK1156073A1 (en) 2012-06-01
CA2478107C (en) 2014-05-13
JP2008200520A (ja) 2008-09-04
EP2075330A1 (de) 2009-07-01
US20100254955A1 (en) 2010-10-07
JP4555576B2 (ja) 2010-10-06
EP2302035A3 (de) 2011-06-01
EP2075330B1 (de) 2016-05-11
US8765468B2 (en) 2014-07-01

Similar Documents

Publication Publication Date Title
DE60327603D1 (de) Chirurgische vorrichtung zur haut-therapie und zum testen
DE502004007735D1 (en) Flächiges implantat
BRPI0507812A (pt) sistema de microativação, método para a microativação das células epidérmicas, kit, método para montar o dispositivo de microativação e método para a microativação da pele
BR0210599A (pt) Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
ATE332668T1 (de) Medizinische vorrichtung zur blutstromsteuerung
NO20042357L (no) Syntetisk matriks for kontrollert celleinnvekst og vevsregenering
ATE485065T1 (de) Gewebekonstruktionsvorrichtungen zur reparatur und regeneration von gewebe
DE602005009642D1 (de) Drahtloses Kommunikationssystem
WO2004113513A3 (en) Methods and compositions for modulating stem cell growth and differentiation
DE60238058D1 (de) Verwendung von lysyloxydase inhibitoren zur zellkultur und gewebeaufbau
DK1625212T3 (da) Kunstigt immunorgan
ATE487503T1 (de) Medizinprodukt mit fixiermitteln
DE60327089D1 (de) Systeme zum verschieben und/oder zurückhalten von gewebe in den oberen atemwegen
EP1653807A4 (de) Dermismikroorgane, verfahren und vorrichtungen zur herstellung und verwendung davon
WO2003083070A3 (en) Endothelial cells derived from human embryonic stem cells
ATE445365T1 (de) Gerät zur exzision von hautläsionen und hautverschlussvorrichtung dafür
WO2011094316A3 (en) Highly compression resistant matrix with porous skeleton
ATE308610T1 (de) Dreidimensionales hautmodell
EP1535514A4 (de) Zusammensetzung f r den schutz von organen, geweben oder zellen und ihre verwendung
WO2004054558A3 (en) Reduction of breast density with 4-hydroxy tamoxifen
WO2006018147A3 (de) Vernetzte kollagenmatrix zur herstellung eines hautäquivalentes
ES2479543T1 (es) Poblaciones celulares que tienen actividad inmunorreguladora, métodos para la preparación y usos de las mismas
HU0401385D0 (en) Tissue cultivating method for culturing skin cells
EP1477191A4 (de) Phosphophoryn enthaltendes biologisches verbundmaterial
DE60234250D1 (de) Vorrichtung zur Zell- bzw. Gewebezüchtung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties