ATE432359T1 - Modulation der s6-kinaseaktivität zur behandlung von adipositas - Google Patents
Modulation der s6-kinaseaktivität zur behandlung von adipositasInfo
- Publication number
- ATE432359T1 ATE432359T1 AT03773650T AT03773650T ATE432359T1 AT E432359 T1 ATE432359 T1 AT E432359T1 AT 03773650 T AT03773650 T AT 03773650T AT 03773650 T AT03773650 T AT 03773650T AT E432359 T1 ATE432359 T1 AT E432359T1
- Authority
- AT
- Austria
- Prior art keywords
- obesity
- modulation
- treatment
- kinase activity
- kinase
- Prior art date
Links
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 102000009738 Ribosomal Protein S6 Kinases Human genes 0.000 abstract 2
- 108010034782 Ribosomal Protein S6 Kinases Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Child & Adolescent Psychology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0224338.4A GB0224338D0 (en) | 2002-10-18 | 2002-10-18 | Modulation of S6 kinase activity for the treatment of obesity |
| US49722703P | 2003-08-22 | 2003-08-22 | |
| PCT/EP2003/011554 WO2004035815A1 (en) | 2002-10-18 | 2003-10-17 | Modulation of s6 kinase activity for the treatment of obestiy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE432359T1 true ATE432359T1 (de) | 2009-06-15 |
Family
ID=32109253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03773650T ATE432359T1 (de) | 2002-10-18 | 2003-10-17 | Modulation der s6-kinaseaktivität zur behandlung von adipositas |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1556505B1 (de) |
| JP (1) | JP2006502744A (de) |
| AT (1) | ATE432359T1 (de) |
| AU (1) | AU2003282035A1 (de) |
| DE (1) | DE60327793D1 (de) |
| ES (1) | ES2328033T3 (de) |
| WO (1) | WO2004035815A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006020755A2 (en) * | 2004-08-10 | 2006-02-23 | Beth Israel Deaconess Medical Center, Inc. | Methods for identifying inhibitors of the mtor pathway as diabetes therapeutics |
| EP1908465B1 (de) * | 2006-10-04 | 2009-04-29 | Centre National De La Recherche Scientifique (Cnrs) | Chlor enthaltende Guanabenz Derivate zur Behandlung von Prionerkrankungen |
| WO2013017656A1 (en) * | 2011-08-02 | 2013-02-07 | Medizinische Universität Wien | Antagonists of ribonucleases for treating obesity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218136B1 (en) * | 1996-03-12 | 2001-04-17 | Smithkline Beecham Corporation | Methods of the identification of pharmaceutically active compounds |
| EP1100929B1 (de) * | 1998-08-04 | 2011-02-09 | Ludwig Institute For Cancer Research | Identifizierung und funktionelle charakterisierung einer ribosomalen s6 proteinkinase |
| AU4683700A (en) * | 1999-04-30 | 2000-11-17 | Beth Israel Deaconess Medical Center | Decreasing adipose mass by altering rsk2 activity |
| WO2001044497A2 (en) * | 1999-12-02 | 2001-06-21 | University Of Dundee | Protein kinase regulation |
-
2003
- 2003-10-17 DE DE60327793T patent/DE60327793D1/de not_active Expired - Lifetime
- 2003-10-17 EP EP03773650A patent/EP1556505B1/de not_active Expired - Lifetime
- 2003-10-17 WO PCT/EP2003/011554 patent/WO2004035815A1/en not_active Ceased
- 2003-10-17 ES ES03773650T patent/ES2328033T3/es not_active Expired - Lifetime
- 2003-10-17 AU AU2003282035A patent/AU2003282035A1/en not_active Abandoned
- 2003-10-17 AT AT03773650T patent/ATE432359T1/de not_active IP Right Cessation
- 2003-10-17 JP JP2005501296A patent/JP2006502744A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1556505B1 (de) | 2009-05-27 |
| JP2006502744A (ja) | 2006-01-26 |
| AU2003282035A1 (en) | 2004-05-04 |
| DE60327793D1 (de) | 2009-07-09 |
| ES2328033T3 (es) | 2009-11-06 |
| EP1556505A1 (de) | 2005-07-27 |
| WO2004035815A1 (en) | 2004-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1556505 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |